A system and a method for guiding and helping an ultrasound scanner user to acquire the correct projection/cut-plane when acquiring images of a physiological structure for comparison with previously acquired images. The ultrasound scanner screen area is divided in two parts, where one part is showing a reference image loop and the other part is showing the live image loop. The correct reference image loop is automatically retrieved from the image frame memory based on which cell in the stress protocol is active. The reference image loop is cycled with a speed which is automatically set by the software based on the current heart rate given by the live ECG acquisition. The display of the reference loop is "reset" (starting from the first image in the loop) at QRS trigger detection from the live ECG signal.