A system and method of assembling an application for processing image or image-derived data is disclosed. The system includes a base operator configured to interface with one or more derivative operator classes, each operator class including an operator object for executing a processing function on the image or image-derived data. A base multiport node class is provided, which is configured to provide a multiport node for each operator object. The multiport nodes instantiates a pluggable operator for connecting the multiport nodes together at runtime according to user-defined parameters. The connection of multiport nodes implements the processing functions of the operator objects to execute the application.