Thomas L ubbers L orrach DE

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Thomas L ubbers -
City: L orrach State/Country: DE	Email and Contact Information

Thomas L ubbers ( L orrach, DE )

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Thomas L ubbers ( L orrach, DE )

US5594135 - Tricyclic DNA gyrase inhibitors - 01/14/1997

The present invention relates to a compound of the formula ##STR1## wherein X.sup.1, R.sup.1, R.sup.2, OP, R.sup.3, R.sup.4, R.sup.5, R.sup.6, and R.sup.0 are as described herein, and their pharmaceutically acceptable salts thereof carrying an acidic and/or basic substituent. The compound of formula I as well as their pharmaceutically acceptable salts inhibit DNA gyrase activity in bacteria and possess antibiotic, especially antibacterial activity against microorganisms and can be used in the control or prevention of infectious diseases.

US5589473 - Mono- and bicyclic DNA gyrase inhibitors - 12/31/1996