An esophageal perfusion catheter, having an outer housing, a plurality of flexible, tubular channel members within said outer housing, and at least two spaced balloon members encompassing said catheter. Two of the channel members are in fluid communication with each of two balloons. One of the balloons is about 150 millimeters from the distal end of said catheter and about 75 millimeters from the other balloon. A third of the tubular channel members is an esophageal perfusion aspirating channel and is in communication with a port at the distal end of the catheter. A fourth of the tubular channel members serves as a gastric aspirating channel. A fifth of the tubular channel members serves as an aspirating channel. The sixth channel member, serves as an air vent. The esophageal perfusion aspirating channel has a ID of about 3 millimeters. The gastric aspirating channel has a ID of about 2 millimeters. The two channel members which communicate with the balloons have a ID of about 1 millimeter. The interior space between the outer housing and the channel members can be filled with silicone.