A method for reducing allergenicity of natural latex rubber. The natural latex rubber, prior to its vulcanization, is admixed with aluminum hydroxide to denature the antigenic protein thus reducing the total protein level considerably. Lignin or fumed silica can also be mixed with the aluminum hydroxide to reduce the protein value in latex. Ideally, the aluminum hydroxide is characterized as having a density of approximately 2.42 g/cm.sup.3 and molecular weight of 78.00.