A three-dimensional printer includes multiple printheads for printing binder and/or colorant onto a bed of build material in a build chamber. The printheads can be mounted on a gantry that is designed for reciprocal displacement across a build chamber along a slow axis. The printheads, in turn, can reciprocally move across the gantry on a fast axis to enable displacement of the printheads along both the fast and slow axes so that the printheads can deposit binder liquid and/or colorant across the surface of a bed of build material in the build chamber.