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Patent # Description
2017/0143701 CARBOHYDRATE METABOLISM-AMELIORATING AGENT
Provided is a safe carbohydrate metabolism-ameliorating agent having an excellent carbohydrate metabolism-ameliorating action, and a safe GLP-1 secretion...
2017/0143700 SYNTHESIS OF (R)-N-METHYLNALTREXONE
This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof...
2017/0143699 EXTENDED RELEASE, ABSUE DETERRENT PHARMACEUTICAL COMPOSITIONS
Pharmaceutical compositions comprising at least one active pharmaceutical ingredient or a pharmaceutically acceptable salt thereof, at least one hydrophilic...
2017/0143698 Compositions and Methods for Delivery of Poorly Soluble Drugs
Described herein are compositions comprising particles of poorly soluble drugs encapsulated by stabilizers. Further described are pharmaceutical compositions...
2017/0143697 METHODS OF PROVIDING ANALGESIA
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a...
2017/0143696 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS,...
The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, ...
2017/0143695 COATED PARTICLES
Porous particles comprising an active ingredient and a coating exhibiting greater dissolution rate in aqueous media than in alcoholic media are disclosed. A...
2017/0143694 METALLOENZYME INHIBITOR COMPOUNDS
The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by...
2017/0143693 COMPOSITIONS AND METHODS FOR TREATMENT
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and...
2017/0143692 COMPOSITIONS AND METHODS FOR TREATMENT
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and...
2017/0143691 COMPOSITIONS AND METHODS FOR TREATMENT
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and...
2017/0143690 COMPOSITIONS AND METHODS FOR TREATMENT
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and...
2017/0143689 C-Met Modulator Pharmaceutical Compositions
Pharmaceutical compositions and unit dosage forms comprising Compound I are disclosed. ##STR00001##
2017/0143688 Multi-Tyrosine Kinase Inhibitors Derivatives and Methods of Use
The present invention is directed to multi-tyrosine kinase inhibitor compounds. The present invention is further directed to compositions comprising those...
2017/0143687 PPAR GAMMA AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS
Methods of treatment of multiple sclerosis (MS) with PPAR.gamma. agonists, and in particular with the compound of formula (I) known as INT131: ##STR00001##
2017/0143686 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASES
Provided are a pharmaceutical composition for preventing or treating neurodegenerative diseases including an agent capable of suppressing expression or...
2017/0143685 Phosphodiesesterase 4 Inhibitors for the Treatment of a Cognitive Deficit
The present invention provides methods of treating cognitive deficits associated with mental retardation. The methods comprise combining cognitive training...
2017/0143684 NOVEL FXR (NR1H4) BINDING AND ACTIVITY MODULATING COMPOUNDS
The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the...
2017/0143683 PHARMACEUTICAL COMPOSITIONS
The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the...
2017/0143682 COMPOSITION COMPRISING COMBINATION OF RAPAMYCIN AND AN ACTIVATOR OF AMP KINASE AND USE THEREOF FOR TREATING...
A formulation, especially one that is topically administered, comprising a combination of rapamcycin and metformin in a molar ratio of about 20:1, 10:1, 5:1,...
2017/0143681 METHODS AND COMPOSITIONS FOR TREATING PAIN
The invention features combinations of dopaminergic agents and analgesic agents useful for treating pain. In particular, the combinations feature a low ratio...
2017/0143680 MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS
The present application provides for a compound of Formula I, ##STR00001## or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions...
2017/0143679 METHODS FOR IMPROVING MUSCLE AND HEART FUNCTION
The present invention encompasses combinations comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods...
2017/0143678 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
Provided is a pharmaceutical composition for oral administration enabling improved solubility, improved dissolution properties, and improved oral absorbability...
2017/0143677 TREATMENT USING DANTROLENE
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for...
2017/0143676 Compositions and Methods for Treatment of Glaucoma
The invention provides .alpha.-2 adrenergic receptor agonist compositions and methods for treating glaucoma and other intraocular conditions. The preferred...
2017/0143675 FORMULATIONS FOR TREATMENT OF HYPERTHYROIDISM
The present invention relates to compositions, in particular for the treatment of hyperthyreosis (also designated hyperthyroidism), especially in cats. These...
2017/0143674 Use of Glutaryl Histamine for the Treatment of Respiratory Tract Diseases
The invention relates to a medicament for the treatment of respiratory tract diseases selected from the group including rhinosinusitis, sinusitis, tonsillitis,...
2017/0143673 Methods For Treating Heart Failure Using Glucagon Receptor Antagonists
The present invention relates to methods for treating or preventing heart failure using a glucagon receptor antagonist or modulator. In various embodiments,...
2017/0143672 TETRAZOLE-SUBSTITUTED ARYLAMIDES AS PX2 AND PX2/3 ANTAGONISTS
A method of antagonizing P2X.sub.3 and/or P2X.sub.2/3 receptors or treating a disease misregulation of P2X.sub.3 and/or P2X.sub.2/3 receptors treating a...
2017/0143671 APREMILAST FOR THE TREATMENT OF A LIVER DISEASE OR A LIVER FUNCTION ABNORMALITY
Methods of treating, managing or preventing liver disease are disclosed. Specific methods encompass the administration of apremilast, alone or in combination...
2017/0143670 ORALLY DISINTEGRATING TABLET CONTAINING ASENAPINE
The present invention relates to an orally disintegrating tablet (ODT) containing asenapine maleate and to a process for preparing the ODT. In a first aspect,...
2017/0143669 LIQUID ORAL COMPOSITIONS
Aqueous suspensions for oral administration are disclosed that include simvastatin having a d.sub.90 of simvastatin particles of less than about 100 .mu.m as...
2017/0143668 USE OF NOBILETIN IN CANCER TREATMENT
The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic...
2017/0143666 COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODEGENERATIVE DISEASES AND...
Provided are compositions comprising compounds or precursors to compounds which may be used for a. variety of therapeutic applications including, for example,...
2017/0143665 SYNTHESIS AND USE OF AMINE-CONTAINING FLAVONOIDS AS POTENT ANTI-LEISHMANIAL AGENTS
The present invention relates to novel series of amine-containing flavonoids and compositions containing the compounds, as well as the synthesis and the use of...
2017/0143664 CANNABINOID FORMULATION FOR THE SEDATION AND/OR ANAESTHETIZING OF A HUMAN OR ANIMAL
A method of sedating and/or anesthetizing a human or animal recipient by administering a formulation including a cannabinoid to the recipient thereby rendering...
2017/0143663 COATING COMPOSITION AND MEDICAL DEVICE
A coating composition for drug-eluting medical devices, which enables a medical device to be delivered to a target tissue for the purpose of treating an...
2017/0143662 TIGLIEN-3-ONE DERIVATIVES
The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections,...
2017/0143661 METHOD FOR REDUCING THE VIRAL LOAD IN POULTRY CHALLENGED WITH NEWCASTLE DISEASE (ND)/ AVIAN INFLUENZA (AI)
A method of reducing viral load in poultry under viral challenge comprising the supplementation of the poultry with an efficacious dosage of a composition...
2017/0143660 METHODS FOR TREATING INFLAMMATION AND PAIN
The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an ...
2017/0143659 METHOD FOR TREATING BLADDER CANCER
A method for treating bladder cancer including the steps of administering an isothiocyanate functional surfactant to an area affected by bladder cancer,...
2017/0143658 METHODS OF REDUCING THE RISK OF A CARDIOVASCULAR EVENT IN A SUBJECT ON STATIN THERAPY
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in...
2017/0143657 COMPOSITIONS AND METHODS FOR REDUCING A FATTY ACID DESATURATION INDEX IN A SUBJECT IN NEED THEREOF
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in...
2017/0143656 METHODS OF REDUCING THE RISK OF A CARDIOVASCULAR EVENT IN A SUBJECT ON STATIN THERAPY
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in...
2017/0143655 FATTY ACID FORMULATIONS AND METHODS OF USE THEREOF
The present invention provides dietary formulations comprising polyunsaturated fatty acids and vitamin E. The present invention further provides methods of...
2017/0143654 GASTRIC RETENTIVE PHARMACEUTICAL COMPOSITIONS FOR TREATMENT AND PREVENTION OF CNS DISORDERS
The present disclosure is directed to methods and compositions for ameliorating, preventing and treating central nervous system (CNS) disorders. The invention...
2017/0143653 USE OF SULINDAC FOR PROTECTING RETINAL PIGMENT EPITHELIAL CELLS AGAINST OXIDATIVE STRESS
Compositions and methods described herein are based on the use of the drug sulindac, a non steroidal anti-inflammatory drug (NSAID), for protecting retinal...
2017/0143652 METHOD FOR REGULATING RETINAL ENDOTHELIAL CELL VIABILITY
Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a...
2017/0143651 COMPOSITIONS OF ABSCISIC ACID FOR ANIMAL HEALTH
The invention relates to compositions comprising abscisic acid, and/or salts, derivatives and analogs thereof, and methods of using the same for improving the...
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