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Patent # Description
2017/0183658 USE OF miR-199a-5p, TARGETS AND/OR INHIBITORS THEREOF FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF...
The present invention relates to the use of the miRNA expression profile, particularly of miR-199a-5p, and the target genes regulated thereby for the...
2017/0183657 METHOD OF SEPARATING SENESCENT CELLS USING OVEREXPRESSION OF PROTOCADHERIN
Provided is a method of separating senescent cells from a sample including the senescent cells, and a method of removing senescent cells from a sample or a...
2017/0183656 COMPOSITION INCLUDING PINT GENE EXPRESSION INHIBITOR OR PINT ACTIVITY INHIBITOR AND USE THEREOF
Provided are a composition for stimulating DNA damage in cells, the composition including a p53 induced non-coding transcript (PINT) gene expression inhibitor...
2017/0183655 COMPOSITIONS AND USES FOR TREATMENT THEREOF
The invention is directed generally to oligonucleotide compositions for the treatment of DNA repeat expansion diseases. The invention also relates to...
2017/0183654 DNA RECOMBINASE CIRCUITS FOR LOGICAL CONTROL OF GENE EXPRESSION
The invention provides, inter alia, recombinase-based systems that provide for integrated logic and memory in living cells such as mammalian cells. The nucleic...
2017/0183653 Pri-mirna libraries and methods for making and using pri-mirna libraries
Provided are methods for the design, preparation, and use of non-native primicroRNAs (pri-miRNAs), pri-microRNA (pri-miRNA) scaffolds, and libraries of...
2017/0183652 LNCRNAS FOR THERAPY AND DIAGNOSIS OF CARDIAC HYPERTROPHY
The present invention relates to a pharmaceutical composition comprising (i) a compound promoting the expression and/or the activity of one or more long...
2017/0183651 HIGH-YIELD METHOD FOR RAPIDLY CONJUGATING RIBONUCLEIC ACID (RNA) TO DIETHYLENETRIAMINE PENTAACETIC ACID (DTPA)
The invention discloses a high-yield method for preparing a ribonucleic acid (RNA)-diethyltriamine pentaacetic acid (DTPA) conjugate. The conjugate is prepared...
2017/0183650 PHARMACEUTICAL COMPOSITIONS COMPRISING RNA AND USE FOR TREATING CANCER
Methods are provided for making an RNA molecule derived from non-coding chimeric mitochondrial RNAs (ncmtRNAs), in particular antisense non-coding chimeric...
2017/0183648 METHOD, KIT AND ARRAY FOR FUNCTIONAL VALIDATION OF RESULTS DERIVED FROM HIGH THROUGHPUT STUDIES
A method of preparing a biomarker functional validation array includes selecting one or more lists of candidate agents, predicting functions of the one or more...
2017/0183647 MUTANT VIRAL CAPSID LIBRARIES AND RELATED SYSTEMS AND METHODS
Provided are mutant viral capsid cell libraries, individual cells of such libraries, systems, vectors, and methods for generating the cell libraries, and...
2017/0183646 METHOD FOR RAPIDLY SCREENING MICROBIAL HOSTS TO IDENTIFY CERTAIN STRAINS WITH IMPROVED YIELD AND/OR QUALITY IN...
The present invention provides an array for rapidly identifying a host cell population capable of producing heterologous protein with improved yield and/or...
2017/0183645 COMPOSITION AND METHOD FOR DIVERSIFYING POLYPEPTIDE LIBRARIES
Provided, among other things, is a yeast cell comprising: (A) a recombinant DNA that constitutively or inducibly expresses a cytidine deaminase comprising...
2017/0183644 DRUG COCKTAIL ANALYSES USING MICROSCALE VORTEX ASSISTED ELECTROPORATION
A vortex flow based method for electroporating molecules, e g., sequentially, into cells is provided. The invention provides a method to determine the effect...
2017/0183643 Polypeptides Having Mannanase Activity and Polynucleotides Encoding Same
The present invention relates to polypeptides having mannanase activity, catalytic domains, and carbohydrate binding modules, and polynucleotides encoding the...
2017/0183642 PAENIBACILLUS LARVAE TREATMENT WITH PHAGE LYSIN FOR AMERICAN FOULBROOD DISEASE
Materials and methods for treating and preventing American Foulbrood disease in honeybees, such as materials and methods for using phage lysin enzymes to lyse...
2017/0183641 CELLULASE HAVING IMPROVED THERMOSTABILITY
A cellulase having improved thermostability is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is...
2017/0183640 REF NUCLEASE FOR SITE SPECIFIC REF-MEDIATED DNA CLEAVAGE
Purified Ref polypeptides with increased nuclease site-specific targeting activity, recombinant nucleic acids and cells for expression of such Ref ...
2017/0183639 CARDIOTONIC STEROID ANTAGONISTS AND RELATED METHODS
Non-naturally occurring peptides are provided that act as a Src SH2 domain antagonist of cardiotonic steroids. Pharmaceutical compositions comprising the...
2017/0183638 SOLUBLE METHANE MONOOXYGENASE PROTEIN VARIANT AND METHOD OF REDUCING CONCENTRATION OF FLUORINATED METHANE IN...
Provided are a recombinant microorganism including an exogenous gene encoding a soluble methane monooxygenase protein, a composition including the soluble...
2017/0183636 Simian Adenoviruses SAdV-36, -42.1, -42.2, and -44 and Uses Thereof
A recombinant vector comprises simian adenovirus 36, simian adenovirus 42.1, simian adenovirus 42.2 and/or simian adenovirus 44 sequences and a heterologous...
2017/0183635 IN VITRO RECONSTITUTED PLANT VIRUS CAPSIDS FOR DELIVERING RNA GENES TO MAMMALIAN CELLS
The invention provides compositions of matter comprising a cowpea chlorotic mottle virus capsid protein (CCMV CP) and a ribonucleic acid, as well as methods...
2017/0183634 TUNING BACTERIOPHAGE HOST RANGE
Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host...
2017/0183633 METHODS USING REPROGRAMMED CELLS FOR REGENERATIVE, RESTORATIVE, AND REJUVENATIVE THERAPIES
Provided herein are methods of treatment to regenerate, restore or rejuvenate a tissue. Methods include making adult somatic and germ cells pluripotent for...
2017/0183632 System and Method for Cold Atmospheric Plasma Treatment on Cancer Stem Cells
A method for treating cancer stem cells with cold atmospheric plasma using a cold atmospheric plasma system The method comprises the steps of placing an exit...
2017/0183631 METHOD FOR MAKING AND USING COLD ATMOMSPHEREIC PLASMA STIMULATED MEDIA FOR CANCER TREATMENT
A method for preparing cold atmospheric plasma stimulated cell culture media with a cold atmospheric plasma system having a delivery port out of which an inert...
2017/0183630 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS
The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present...
2017/0183629 ENGINEERED TISSUE CONSTRUCTS
A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate...
2017/0183628 NOVEL METHODS AND CULTURE MEDIA FOR CULTURING PLURIPOTENT STEM CELLS
Provided is an isolated population of human pluripotent stem cells comprising at least 50% human pluripotent stem cells characterized by an ...
2017/0183627 FUNCTIONAL OLIGODENDROCYTES DERIVED FROM PLURIPOTENT STEM CELLS AND METHODS OF MAKING AND USING THE SAME
Described is the efficient and robust generation of oligodendrocyte progenitor cells (OPCs) and oligodendrocytes from pluripotent stem cells (PSCs). The...
2017/0183626 DEFINED MEDIA FOR EXPANSION AND MAINTENANCE OF PLURIPOTENT STEM CELLS
The present invention provides methods to promote the proliferation of undifferentiated pluripotent stem cells in defined media. Specifically, the invention...
2017/0183624 DIFFERENTIATION OF PLURIPOTENT STEM CELLS
The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention is directed to methods and...
2017/0183623 PREPRIMITIVE STREAK AND MESENDODERM CELLS
This disclosure relates to compositions comprising human preprimitive streak cells and/or human mesendoderm cells as well as methods for their production....
2017/0183622 BIOPAPERS AS A SUBSTRATE FOR TISSUE CULTURE
A biocompatible membranes made by electrospinning a polymer, having living cells on both surfaces of the membrane, and/or is free of a non-biodegradable...
2017/0183621 CULTURE METHOD AND CELL CLUSTER
The present invention provides a culture method for culturing, in recesses (10), a population including two or more cells including a cell derived from a stem...
2017/0183620 USE OF URIC ACID FOR CULTURING BACTERIA SENSITIVE TO OXYGEN TENSION
The present invention relates to a method for cultivating in vitro in an acellular culture medium, bacteria for which the growth is sensitive to oxygen...
2017/0183619 Cell Separation Devices, Systems, and Methods
Disclosed herein are cell separation devices, methods and systems, as well as compositions and reagents for use in cell separation methods.
2017/0183618 APPARATUS FOR PRODUCING ORGANIC SUBSTANCE FROM WASTE AND METHOD FOR PRODUCING ORGANIC SUBSTANCE FROM WASTE
The present invention provides an apparatus and a method which can be used for producing an organic substance effectively from a synthesis gas obtained from a...
2017/0183617 FLUID MIXING SYSTEM WITH LATERALLY DISPLACED FLEXIBLE DRIVE LINES AND METHODS OF USE
A fluid mixing system includes a container bounding a compartment and extending between a first end and an opposing second end. An elongated first drive line...
2017/0183616 SYSTEMS AND METHODS FOR BIOMIMETIC FLUID PROCESSING
Systems and methods generating physiologic models that can produce functional biological substances are provided. In some aspects, a system includes a...
2017/0183615 BIOMASS PRODUCTION SYSTEM AND APPARATUS
A growth module for growing biomass comprising a plurality of growth columns connected together. Each growth column comprises a vertically oriented, hollow,...
2017/0183613 EMULSIFIED FLAVOR COMPOSITION FOR ALCOHOLIC BEVERAGES
The present invention relates to an emulsified flavor composition for an alcoholic beverage that does not generate a floating matter or a sediment, that...
2017/0183612 ENHANCEMENT OF BEER FLAVOR BY A COMBINATION OF PICHIA YEAST AND DIFFERENT HOP VARIETIES
It has unexpectedly been found that Pichia spp. strains have advantageous properties useful in the beer fermentation process. In particular, Pichia spp. yeast...
2017/0183611 ENERGY SAVING BREWING METHOD
Barley based beverages are produced in large quantities, employing highly energy consuming methods, for example in the malting and brewhouse facilities for...
2017/0183610 MODULAR LIQUID INFUSING, FLAVORING, AND DISPENSING DEVICE
The present invention is directed to a Modular Liquid Infusing, Flavoring and Dispensing Device that provides a means to infuse flavor into liquids for...
2017/0183609 LIQUID LAUNDRY DETERGENT COMPOSITION
The present invention relates to liquid laundry detergent compositions comprising a polyetheramine.
2017/0183608 DISHWASHING PASTES
Described herein, are dishwashing paste compositions comprising: an abrasive; a pH modifying agent in an amount effective to provide a pH greater than 7; a...
2017/0183607 LIQUID COMPOSITION FOR CLEANING SEMICONDUCTOR DEVICE, AND METHOD FOR CLEANING SEMICONDUCTOR DEVICE
A liquid semiconductor device cleaning composition used in a process of fabricating a semiconductor integrated circuit, for removing a hard mask or a dry etch...
2017/0183606 HARD SURFACE CLEANING COMPOSITIONS
Cleaning compositions that include a non-functionalized alkyl polyglycoside, a nonionic surfactant system, and water. In certain embodiments, the cleaning...
2017/0183604 SOLVENT EXTRACTION OF OIL FROM DISTILLERS DRIED GRAINS AND METHODS OF USING EXTRACTION PRODUCTS
A process for extraction of crude oil from distillers dried grain solubles and/or distillers dried grains and producing corn distillers meal that may be used...
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