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Patent # Description
2017/0191049 CARBOHYDRATE-BINDING PROTEIN
The carbohydrate processing enzyme PNGase F was catalytically inactivated through mutation. Additional mutations yielded a catalytically inactive ...
2017/0191048 CELLOBIOHYDROLASE HAVING IMPROVED THERMAL STABILITY
The disclosure provides a polypeptide with a mutation having cellobiohydrolase activity and improved thermal stability.
2017/0191047 ADENOSINE-SPECIFIC RNASE AND METHODS OF USE
Provided herein are proteins having A-specific RNase activity. A protein having A-specific RNAse activity is referred to herein as a Csx1 protein. A Csx1...
2017/0191046 LACTONE HYDROLASE AND METHOD OF DEGRADING ALPHA-ZEARALENOL USING THE SAME
A lactone hydrolase having improved activity towards .alpha.-zearalenol is disclosed. The lactone hydrolase has a modified amino acid sequence of SEQ ID NO: 5,...
2017/0191045 TELOMERASE REVERSE TRANSCRIPTASE-BASED THERAPIES FOR TREATMENT OF CONDITIONS ASSOCIATED WITH MYOCARDIAL INFARCTION
The invention provides compositions and methods useful for the treatment and prevention of conditions associated with myocardial infarction.
2017/0191044 DNA POLYMERASES WITH IMPROVED ACTIVITY
Disclosed are DNA polymerases having increased reverse transcriptase efficiency, mismatch tolerance, extension rate and/or tolerance of RT and polymerase...
2017/0191043 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS
The present disclosure relates to transaminase polypeptides capable of aminating a dicarbonyl substrate, and polynucleotides, vectors, host cells, and methods...
2017/0191042 CYTOKININ SYNTHASE ENZYMES, CONSTRUCTS, AND RELATED METHODS
The present disclosure relates to a new class of cytokinin biosynthetic enzymes, cytokinin synthases, which have two domains: an isopentenyl transfer...
2017/0191041 MATERIALS AND METHODS FOR TREATING DISORDERS ASSOCIATED WITH SULFATASE ENZYMES
The subject invention concerns materials and methods for treating or preventing disease and conditions associated with various sulfatase enzymes that are...
2017/0191040 VACCINE FOR IMMUNOCOMPROMISED HOSTS
The invention provides peptides derived from a ubiquitous protein, and nucleic acids encoding such peptides. The invention extends to various uses of these...
2017/0191039 RECOMBINANT AAVS HAVING USEFUL TRANSCYTOSIS PROPERTIES
The disclosure in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capab- lities. In some aspects, the disclosure...
2017/0191038 TGF SIGNALING INDEPENDENT NA VE INDUCED PLURIPOTENT STEM CELLS, METHODS OF MAKING AND USE
Provided is a cocktail of factors for converting/reprogramming non-naive pluripotent stem cells into TGF.beta. signaling-independent (TSI) naive induced...
2017/0191037 METHOD AND CONTAINER FOR CULTURING UNDIFFERENTIATED INDUCED PLURIPOTENT STEM CELL
Provided are a method of culturing an induced pluripotent stem cell and a method of forming a spheroid of the induced pluripotent stem cell. According to an...
2017/0191036 METHOD FOR CULTURING MESENCHYMAL STEM CELLS
Disclosed is a method for culturing mesenchymal stem cells, comprising culturing mesenchymal stem cells in a medium containing calcium in a concentration of...
2017/0191035 Ex Vivo Browning of Adipose Tissue Therapy for Reversal of Obesity and Type II Diabetes
Provided are methods, apparatus, pharmaceutical compositions, and kits for treatment of a metabolic condition, including obesity and type 2 diabetes, by...
2017/0191034 A METHOD TO UP-REGULATE CANCER STEM CELL MARKERS FOR THE GENERATION OF ANTIGEN SPECIFIC CYTOTOXIC EFFECTOR T CELLS
The invention concerns a method of preparing a composition comprising stimulated immune system cells such as dendritic cells (DC) for use in inducing immune...
2017/0191033 METHOD FOR PREPARATION OF RETINAL GANGLION CELLS
An object of the present invention is to provide a method of inducing pluripotent stem cells to differentiate into clinically applicable retinal ganglion...
2017/0191032 IDENTIFICATION AND ISOLATION OF NEURAL STEM CELLS AND NEUROSPHERE INITIATING CELLS
The disclosure reports on the identification and isolation of adult mouse lateral ventricle subventricular zone (SVZ) neurosphere initiating cells (NICs) by...
2017/0191031 SYSTEMS AND METHODS FOR STEM CELL DIFFERENTIATION
The present invention relates to compositions and method for differentiating stem cells. In particular, the present invention relates to methods of generating...
2017/0191030 IMPROVED CULTURE METHOD FOR ORGANOIDS
The invention relates to improved culture methods for expanding epithelial stem cells and obtaining organoids, to culture media involved in said methods, and...
2017/0191029 METHODS FOR IMPROVEMENT OF SEMEN QUALITY
A method for improving quality of a mammalian semen sample includes providing an insoluble carrier carrying at least one ligand that binds to an indicator of...
2017/0191028 METHODS OF DEVELOPING PLANT SOMATIC EMBRYOS
Methods of developing plant somatic embryos include incubating the plant somatic embryos at a first temperature for a first period of time followed by storing...
2017/0191027 Methods and Compositions For Treating Disease
The present invention relates to methods and compositions for treating a subject comprising destroying diseased cells in the subject. The methods comprise...
2017/0191026 CELL CULTURE SUBSTRATE
The invention provides a substrate for cell culture comprising a polymer, wherein the polymer comprises --a homopolymer formed from a monomer of formula (Ia)...
2017/0191025 COMPOUNDED MEDIA POWDER FORMULATION AND METHOD OF PREPARATION OF LIQUID MEDIUM FOR CELL CULTURE
The present invention provides a compounded cell culture medium powder formulation comprising: a basal medium powder and a cell culture media supplement,...
2017/0191024 METHOD FOR INDUCING THE SYNTHESIS OF PHYCOBILIPROTEINS.
The present invention relates to a method for preparation of a biomass of photosynthetic microalgae having a phycobiliprotein content equal to at least 20% of...
2017/0191023 RECOMBINANT THRAUSTOCHYTRIDS THAT GROW ON XYLOSE, AND COMPOSITIONS, METHODS OF MAKING, AND USES THEREOF
The present invention is directed to recombinant thraustochytrids that grow on xylose and cell cultures comprising the recombinant thraustochytrids as well as...
2017/0191022 BIOREACTOR USING ACOUSTIC STANDING WAVES
A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be...
2017/0191021 CELL CULTURE DEVICE AND METHOD
A cell culture device and a cell culture method that enable living tissues for transplantation having constant qualities to be stably supplied as products are...
2017/0191020 THERMOCHROMIC SENSING DEVICES, SYSTEMS, AND METHODS
A test vessel includes one or more test locations configured to contain a medium suitable for culturing a live substance. A thermochromic material is thermally...
2017/0191019 Cell Dispersion Measurement Mechanism, and Cell Subculture System Utilizing Same
The present invention addresses the problem of providing: a cell dispersion measurement mechanism whereby it becomes possible to fully disperse cells...
2017/0191018 BIOCHEMICAL REACTOR WITH SIDE NOZZLES
This disclosure describes a biochemical reactor with side nozzles. The biochemical reactor may include a tank configured to house immobilized carriers and...
2017/0191017 SYSTEM AND METHOD TO MONITOR VISCOSITY CHANGES OF A FLUID STORED IN A VOLUME
A system and method for monitoring viscosity changes of a fluid stored in a volume are provided. The system includes a flexible chamber configured to receive...
2017/0191016 ADJUSTABLE HEIGHT HARVEST VALVE ASSEMBLY FOR BIOREACTORS
An adjustable harvest valve assembly for a bioreactor system which offers all of the benefits of a harvest port, while allowing cell-free liquid to be...
2017/0191015 GAS HEATING APPARATUS FOR DISPOSABLE BIOREACTOR
The present invention relates to an apparatus comprising a single-use circular bag having a sealed edge, capable of holding a nutrient media and designed to...
2017/0191014 SYSTEMS AND TRAYS FOR PROCESSING SAMPLES BY A ROBOTIC PLATFORM
A system for processing samples by a robotic platform has a tray that defines a well defining a drain. The well has a bottom surface, an access port in fluid...
2017/0191013 CONTAINER FOR CULTURING ORGANISMS, METHOD FOR MONITORING THE CULTURING OF ORGANISMS INSIDE SAID CONTAINER, AND...
A shallow container for culturing organisms includes a holder defining a cavity and a separate lid to close off the cavity. The lid includes a transparent...
2017/0191012 CULTURE FLASK
A culture flask comprising a culture chamber in a flask body comprising an even bottom wall with a growth surface on the top side, an even cover wall at a...
2017/0191011 TISSUE ENGINEERED MODEL
A tissue engineered model (TEM) structure, an apparatus and method for making a TEM structure, and methods of using a TEM structure are disclosed. In an...
2017/0191010 Bactericidal, Fungicidal and Anti-Allergenic Zanthoxylum Schinifolium Skin Care Soap and Method of Preparation
The present invention discloses a method of preparing a bactericidal, fungicidal and anti-allergenic Zanthoxylum schinifolium skin care soap, wherein the...
2017/0191009 SOLID CONCENTRATE COMPOSITIONS CONTAINING ZINC PYRITHIONE
The present invention relates to a solid concentrate composition comprising: (a) from 5% to 25% by weight of zinc pyrithione (ZPT); (b) from 8% to 85% by...
2017/0191008 MICROEMULSIONS AND USES THEREOF
The present disclosure is directed to compositions including a microemulsion comprising a blend of lecithin, a co-surfactant and a salt of an acidifier, an...
2017/0191006 METHOD FOR CLEANING SYSTEMS
A method is provided for cleaning a system by conducting continuously through the system a cleaning composition including at least one oxidizing agent and an...
2017/0191005 AQUEOUS LIQUID DETERGENT FORMULATION COMPRISING ENZYME PARTICLES
The present invention relates to an aqueous liquid laundry formulation comprising an ester based laundry ingredient; an effective cleaning amount of protease...
2017/0191004 Automatic Dishwashing Composition
The present invention relates to an improved detergent composition for use in the protection of non-metallic inorganic materials such as glassware in automatic...
2017/0191003 Structured Liquid Compositions
Microfibrillated cellulose, derived from vegetables or wood, can be used to provide a liquid composition which is compatible with a broad range of ingredients...
2017/0191002 TREATMENT COMPOSITIONS
The present invention relates to treatment compositions containing polymer systems that provide stability and benefit agent deposition as well as methods of...
2017/0191001 Microcapsules Formed From Phosphate Esters And Compositions Containing Same
Microcapsules can be formed of a phosphate ester and a multivalent ion. The microcapsules can encapsulate a core material having a C log P value of about 0 or...
2017/0191000 Starch Benefit Agent Delivery Vehicle
A starch delivery vehicle which includes a starch, a core material, and a lipophilic phosphate ester, wherein the lipophilic phosphate ester at least partially...
2017/0190999 POLYALKYLENE GLYCOL-BASED INDUSTRIAL LUBRICANT COMPOSITIONS
A lubricant composition comprises as a lubricant base, an oil soluble polyalkylene glycol suitable for use as a lubricant in an industrial oil, grease or metal...
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