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Patent # Description
2017/0189382 COMPOUNDS FOR TREATING BRAIN CANCER
There is provided a compound of formula I or a pharmacologically acceptable salt thereof: ##STR00001## for use in the treatment of a brain cancer selected from a...
2017/0189381 PRIMARY AMINES AND DERIVITVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT...
The present invention pertains to certain compounds of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT.sub.2A...
2017/0189380 TRYPTAMINE-BASED SHIP INHIBITORS FOR THE TREATMENT OF CANCER
The present disclosure provides compositions that inhibit the SH2-containing inositol 5'-phosphatase (SHIP), as well as methods using such compositions for use...
2017/0189379 COMBINATION THERAPIES WITH CURAXINS
Provided are methods and compositions that relate to, inter alia, CBL0137 for the treatment of various cancers, optionally in combination with various agents.
2017/0189378 COMPOUNDS FOR THE TREATMENT OF CANCERS ASSOCIATED WITH HUMAN PAPILLOMAVIRUS
The present invention relates to the pyrrolidine substituted with flavone derivatives, represented by the compounds of Formula (I) or a pharmaceutically...
2017/0189377 CHLOROPHYLL C CONTAINING DEGRANULATION SUPPRESSOR
Degranulation suppressors are provided that are effective against allergic disease and osteoarthritis. The degranulation suppressors contain chlorophyll c.
2017/0189376 BUTYROYLOXYMETHYL DIETHYL PHOSPHATE COMPOUNDS AND USES THEREOF
Methods for treating ameliorating, reducing and/or preventing a cutaneous T-cell lymphoma in a subject in need thereof, comprising administration ...
2017/0189375 METHOD OF TREATMENT OF A MUCOPOLYSACCHARIDOSIS
The present invention relates to the use of 4-methyl-2-oxo-2H-1-benzopyran-7-yl-5-thio-.beta.-D-xylopyranoside in the treatment of a mucopolysaccharidosis such...
2017/0189374 ZALTOPROFEN AND MUSCLE RELAXANT COMBINATIONS
The present invention relates to a novel pharmaceutical composition comprising zaltoprofen or a pharmaceutically acceptable salt thereof in combination with...
2017/0189373 Terpene Control in Scaleable Cannabinoid Medicinal Formulations
The present invention administers a cannabinoid medication to a patient followed by observing one or more physiological responses in the patient during a first...
2017/0189372 USE OF SUBSTITUTED CHROMAN COMPOUNDS
A substituted chroman compound includes R.sup.1a and R.sup.1b as substituents selected from hydrogen and phenyl optionally substituted with 1-3 substituents....
2017/0189371 HNF4-alpha ANTAGONIST AND USE THEREOF
Provided is a hepatocyte nuclear factor 4 alpha (HNF4-.alpha.) antagonist and a use thereof. The HNF4-.alpha. antagonist selected in the present invention was...
2017/0189370 FLUORINATED BENZOFURAN DERIVATIVES
The invention relates to fluorinated compounds and their use in the field of pathological syndromes of the cardiovascular system. Novel fluorinated benzofuran...
2017/0189369 MULTI-ARM POLYMERIC ALKANOATE CONJUGATES
Among other aspects, provided herein are multi-armed polymer conjugates comprising an alkanoate-linker, compositions comprising such conjugates, and related...
2017/0189368 STABLE FORMULATIONS FOR LYOPHILIZING THERAPEUTIC PARTICLES
The present disclosure generally relates to lyophilized pharmaceutical compositions comprising polymeric nanoparticles which, upon reconstitution, have low...
2017/0189367 Lobaplatin Crystal, Preparation Method And Pharmaceutical Application
The present invention relates to new crystals A, B and F of lobaplatin as well as preparation methods therefor and pharmaceutical applications thereof....
2017/0189366 METHOD FOR TREATING DISORDERS RELATED TO COMPLEMENT ACTIVATION
A method for treating or preventing a complement activated T-cell mediated disorder in a subject includes administering a therapeutically effective amount of a...
2017/0189365 Treatment and Prevention of Liver Disease Associated with Parenteral Nutrition (PN)
The present invention is based on the discovery that parenteral nutrition (PN) induced liver disease, e.g. fatty liver disease, can be prevented and even...
2017/0189364 COMPOSITIONS COMPRISING ORNITHINE AND PHENYLACETATE OR PHENYLBUTYRATE FOR TREATING HEPATIC ENCEPHALOPATHY
The present invention relates to use of ornithine in the manufacture of a medicament for use in combination with at least one of phenylacetate and ...
2017/0189363 GASTRIC ACID MODULATORS FOR ORAL DELIVERY OF PEPTIDES AND PROTEINS
Described are methods for oral administration of therapeutic proteins and peptides, more specifically to the oral administration of therapeutic proteins and...
2017/0189362 TUNEABLE DELIVERY OF NANOPARTICLE BOUND ACTIVE PLASMIN FOR THE TREATMENT OF THROMBOSIS
Compositions and methods for therapeutic delivery are disclosed. More particularly, the present disclosure relates to nanoparticle compositions that sequester...
2017/0189361 EYE DROPS FOR TREATING DRY EYE
The present invention aims to provide an ophthalmic solution for the treatment of dry eye which is used to inhibit apoptosis caused by tear hyperosmolarity....
2017/0189360 METHOD, COMPOSITION AND PACKAGE FOR BOWEL CLEANSING
The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When...
2017/0189359 Graphene Nanostructure-Based Pharmaceutical Composition for Preventing or Treating Neurodegenerative Diseases
The present disclosure relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases, the pharmaceutical composition including...
2017/0189358 SORBIC AND BENZOIC ACID AND DERIVATIVES THEREOF ENHANCE THE ACTIVITY OF A NEUROPHARMACEUTICAL
Methods and compositions are provided for treating neuropsychiatric disorders such as schizophrenia, depression, attention deficit disorder, mild cognitive...
2017/0189357 METHODS OF LIMITING MORBIDITY IN HEMOGLOBINOPATHIES
Methods of alleviating the symptoms of hemoglobinopathies, including, but not limited to, sickle cell disease, .beta.-thalassemia, and hemoglobin H disease are...
2017/0189356 SOLID ORAL FORMULATION OF FENRETINIDE
Amorphous solid dispersions suitable for oral delivery comprising fenretinide or an analog thereof and at least one matrix polymer, and processes for making...
2017/0189355 USE OF KUKOAMINE A AND KUKOAMINE B
The use of Kukoamine A and Kukoamine B in the preparation of drugs for the prevention and treatment of sepsis and autoimmune disease is disclosed. Bacterial...
2017/0189354 PHARMACEUTICAL COMPOSITION COMPRISING RIMEPORIDE FOR TREATING DISEASES ASSOCIATED WITH INSULIN RESISTANCE AND...
The invention relates to a pharmaceutical composition comprising as active ingredient an effective amount of ...
2017/0189353 DOSAGE REGIMEN FOR A S1P RECEPTOR AGONIST
S1P receptor modulators or agonists are administered following a dosage regimen whereby during the initial days of treatment the daily dosage is lower than the...
2017/0189352 EPINEPHRINE FORMULATIONS
Pharmaceutical compositions comprising epinephrine, methods of administration, and methods of making the same. Compositions may comprise at least one of an...
2017/0189351 CAPSULE DOSAGE FORM OF METOPROLOL SUCCINATE
This disclosure provides an extended-release capsule dosage form of metoprolol succinate in the form of coated discrete units, wherein said capsule dosage form...
2017/0189350 METHODS OF TREATMENT OF TEMOZOLOMIDE-RESISTANT GLIOMA USING COENZYME Q10
The invention provides methods and compositions for treatment of a subject with a glioma that has failed treatment with temozolomide (TMZ) comprising...
2017/0189349 Onychomycosis Treatment System and Method
A system and method includes delivery of a redox gas solution to treat onychomycosis, wherein the redox gas solution comprises a reactive species dissolved in...
2017/0189348 SYSTEMS AND METHODS FOR LONG TERM TRANSDERMAL ADMINISTRATION
Devices, systems, compositions and methods for long term or prolonged transdermal administration of an active agent are provided.
2017/0189347 TRANSDERMAL DELIVERY SYSTEM
Embodiments of the invention relate generally to the field of transdermal delivery and more specifically to transdermal patches containing rasagiline for the...
2017/0189346 UNIFORM FILMS FOR RAPID-DISSOLVE DOSAGE FORM INCORPORATING ANTI-TACKING COMPOSITIONS
The present invention relates to water-soluble films incorporating anti-tacking agents and methods of their preparation. Anti-tacking agents may improve the...
2017/0189345 NANOENCAPSULATION OF ANTIGEN-BINDING MOLECULES
The present invention relates to nanospheres comprising a polymeric matrix and antigen-binding molecules esterase-releasably incorporated therein. The...
2017/0189344 HIGHLY DRUG-LOADED POLY(ALKYL 2-CYANOACRYLATE) NANOCAPSULES
The present invention relates to nanocapsules which are stabilized by a bile acid or salt thereof. The nanocapsules comprise a polymeric shell formed by...
2017/0189343 DRUG CARRIER FOR TUMOR-SPECIFIC TARGETED DRUG DELIVERY AND USE THEREOF
The present disclosure relates to a tumor-targeted drug delivery system, comprising a tumor-targeted drug carrier and a tumor-treating drug, wherein the...
2017/0189342 Methods and Compositions for the Treatment of Seizure-Related Disorders
Compositions and methods are provided for administering a pharmaceutical composition to a human patient. Compositions are administered to a human patient...
2017/0189341 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HELICOBACTER PYLORI
Single oral solid dosage form comprising an immediate release first dosage composition having at least two antibiotic agents and a delayed release second...
2017/0189340 ANTIEMETIC EXTENDED RELEASE SOLID DOSAGE FORMS
A solid oral dosage form includes a core comprising a non-ionic polymer matrix, a first amount of a first antiemetic drug or a pharmaceutically acceptable salt...
2017/0189339 ABUSE DETERRENT IMMEDIATE RELEASE BIPHASIC MATRIX SOLID DOSAGE FORM
An abuse deterrent immediate release biphasic matrix solid dosage form that releases the drug at a desired rate for quick onset of action when a single unit or...
2017/0189338 TABLETING AGENT HAVING A LOW WATER CONTENT, AND METHOD FOR THE PRODUCTION THEREOF
The present invention relates to a Tabletting aid with a low water content and to a process for the preparation thereof. The Tabletting aid composition is a...
2017/0189337 Therapeutic Compositions for Treatment of Human Immunodeficiency Virus
A solid oral dosage form is provided, comprising a compound of Formula I or a pharmaceutically acceptable salt thereof, tenofovir alafenamide or a ...
2017/0189336 CO-GRANULES OF XANTHAN GUM AND ACACIA GUM
The invention relates to a co-granule of xanthan gum and acacia gum having an average diameter of between 50 .mu.m and 1000 .mu.m.
2017/0189335 DOSAGE AND ADMINISTRATION FOR PREVENTING CARDIOTOXICITY IN TREATMENT WITH ERBB2-TARGETED IMMUNOLIPOSOMES...
Methods for determining dosage of HER2-targeted anthracycline-containing immunoliposomes are disclosed, as are methods of treating cancer patients with...
2017/0189334 PEPTIDE HYDROGEL PROPERTIES AND ITS APPLICATIONS
Peptide hydrogels having a self-assembling, 3-dimensional nanofiber matrix are described. The nanofiber matrix comprises an amphiphilic peptide and optionally...
2017/0189333 Aqueous gel composition and its use
An aqueous gel composition comprising a) water, at least one polysaccharide and at least one high molecular weight polyethylene oxide, wherein the water...
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