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Patent # Description
2017/0204476 MICRORNA POLYMORPHISMS CONFERRING ENHANCED DROUGHT TOLERANCE IN A PLANT
Methods of identifying a single nucleotide polymorphism associated with a plant trait and methods of identifying a plant having an improved trait. The plant...
2017/0204474 Bulk Allele Discrimination Assay
A method is described for bulk allele discrimination of multiple single nucleotide polymorphisms in multiple individuals. Also described is a kit for use in...
2017/0204473 MAIZE EVENT DP-032218-9 AND METHODS FOR DETECTION THEREOF
The disclosure provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the...
2017/0204472 GENETIC SIGNATURE OF VULNERABILITY TO INHIBITORS OF BASE EXCISION REPAIR (BER) IN CANCER
The invention relates to the identification of genetic signatures and expression profiles that are a part of the Base Excision Repair (BER) pathway, a major...
2017/0204471 METHODS AND NUCLEOTIDE FRAGMENTS OF PREDICTING OCCURRENCE, METASTASIS OF CANCERS AND PATIENTS' POSTOPERATIVE...
Provided in the present invention are a method using in vitro measurement of the content of methylation or demethylation of GFRa1 CpG islands to estimate a...
2017/0204470 METHODS AND COMPOSITIONS FOR DETECTING GASTROINTESTINAL AND OTHER CANCERS
This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin...
2017/0204469 REPORTER VECTOR FOR EVALUATING CHARACTERISTICS OF SUBJECT CELL, ASSAY KIT, PROCEDURE AND DEVICE
According to one embodiment, a reporter vector includes a first and a second reporter gene expression unit and a replication initiation sequence. The first...
2017/0204468 USE OF H2A.Z.1 AS A HEPATOCELLULAR CARCINOMA BIOMARKER
The present disclosure relates to a use of H2AFZ as a hepatocellular carcinoma (HCC) biomarker and more particularly, to a marker for diagnosing hepatocellular...
2017/0204467 LUNG CANCER DETERMINATIONS USING MIRNA
The present invention provides a method of determining the presence of a pulmonary tumor in a subject is provided. Also provided is a method of determining the...
2017/0204466 BIOMARKERS FOR PIN1-ASSOCIATED DISORDERS
Biomarkers and driver mutations for diagnosis and prognosis of Pin 1-associated diseases are disclosed. In one embodiment, the methods for diagnosis of Pin...
2017/0204465 FETAL CHROMOSOMAL ANEUPLOIDY DIAGNOSIS
The invention relates to prenatal detection methods using non-invasive techniques. In particular, it relates to prenatal diagnosis of a fetal chromosomal...
2017/0204464 PROCESS AND MOLECULAR BIOMARKER
A process and molecular biomarker for platelets stored in blood banks provides for efficient verification of which platelet concentrate bags are in good...
2017/0204463 METHOD FOR PREDICTING RISK OF ANKYLOSING SPONDYLITIS USING DNA COPY NUMBER VARIANTS
The present invention relates to a method of predicting the risk of developing ankylosing spondylitis using DNA copy number variation. It was verified that the...
2017/0204462 MULTIPLEXED NUCLEIC ACID TARGET IDENTIFICATION BY STRUCUTRE BASED PROBE CLEAVAGE
The present invention provides for novel methods and compositions for nucleic acid sequence detection. Unique, identifying cleavage fragments from probes,...
2017/0204461 KITS AND METHODS FOR MULTIPLEX ANALYSIS OF 13 MR Y-STRS
Provided are methods and kits that allow the amplification, in a single multiplex reaction, of the thirteen rapidly mutating Y chromosome short tandem repeats...
2017/0204460 System and Methods for Massively Parallel Analysis of Nucleic Acids in Single Cells
Methods and systems are provided for massively parallel genetic analysis of single cells in emulsion droplets or reaction containers. Genetic loci of interest...
2017/0204459 METHOD FOR IDENTIFICATION AND ENUMERATION OF NUCLEIC ACID SEQUENCE, EXPRESSION, COPY, OR DNA METHYLATION...
The present invention relates to a method for the highly specific, targeted capture of regions of human genomes and transcriptomes from the blood, i.e. from...
2017/0204458 LABELLED NUCLEOTIDES
Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.
2017/0204457 METHOD FOR CHARACTERISING A DOUBLE STRANDED NUCLEIC ACID USING A NANO-PORE AND ANCHOR MOLECULES AT BOTH ENDS OF...
The invention relates to a method for method of characterising, such as sequencing, a target double stranded polynucleotide. The polynucleotide is coupled to a...
2017/0204456 ISOTHERMAL METHODS FOR AMPLIFYING NUCLEIC ACID SAMPLES
The description provides two-stage methods of nucleic acid amplification and detection reactions, which are useful for rapid pathogen detection or disease...
2017/0204455 Method for Detecting a Genetic Variant
The present invention provides a method for detecting a genetic variant in a region of interest in a DNA sample comprising (i) determining, for a given...
2017/0204454 ANTIBODIES THAT BIND THERMOPHILIC DNA POLYMERASES
This disclosure relates to antibodies that bind thermophilic family B DNA polymerases. Related uses, methods, and compositions are also provided.
2017/0204453 Methods for Forensic DNA Quantitation
Described herein are methods and devices for nucleic acid quantification and, in particular, to microfluidic methods and devices for nucleic acid ...
2017/0204452 METHOD FOR THE DETECTION OF SEPSIS
The invention relates to an in vitro method for the detection and/or identification of a human pathogen and/or genetic material thereof comprising subjecting a...
2017/0204451 PREPARATION OF STABILIZER-FREE GOLD SOLS AND THEIR CONFIGURATION INTO A GELATIN-COATED PROTEASE-INDICATING...
A method of detecting protease activity in a sample. The method includes contacting the sample with a composition containing (i) a dispersion of gold...
2017/0204450 METHOD AND ENZYME SOLUTION FOR FLOW-CYTOMETRIC DETECTION OF LIGHT CHAIN RESTRICTION
The invention relates to an enzyme solution, which is used preferably for pre-treating mammalian cells for flow-cytometric detection of light chain restriction...
2017/0204449 METHOD FOR CHARACTERIZING BACTERIAL MUTANTS
Disclosed is a method for characterizing the effect of an antibiotic on a bacterium, the method comprising the steps of: (a) generating a pool of mutant...
2017/0204448 IDENTIFICATION OF MICROORGANISMS USING MALDI-TOF-MS ON-PLATE EXTRACTION
Rapid methods that identify sepsis-causing bacteria or yeast aid the physician in critical therapeutic decision-making, thus decreasing patient mortality...
2017/0204447 COMPOSITIONS AND METHODS FOR CHARACTERIZING AND DIAGNOSING PERIODONTAL DISEASE
The present disclosure relates to methods for characterizing and diagnosing dental diseases. In particular, the present disclosure relates to methods for...
2017/0204446 System for rapid continuous manufacturing of monoclonal antibodies
Described herein is a rapid continuous biomanufacturing platform process that combines a perfusion mammalian cell culture with a synchronized purification of...
2017/0204445 IN VIVO SITE-SPECIFIC PROTEIN TAGGING USING ENGINEERED SORTASE VARIANTS
Engineered sortase variants are shown to have promiscuous activity that allow proteins to be tagged using a diverse array of small, commercially available...
2017/0204444 CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS
The present invention provides a one-pot multi-enzyme method for preparing UDP-sugars from simple sugar starting materials. The invention also provides a...
2017/0204443 BIOTECHNOLOGICAL PRODUCTION OF LNT, LNNT AND THE FUCOSYLATED DERIVATIVES THEREOF
The present invention relates to primarily genetically modified microorganisms for in vivo synthesis of lacto-N-tetrose (LNT) and lacto-N-neotetrose (LNnT),...
2017/0204441 Enzyme Compositions and Uses Thereof
The present invention relates to enzyme compositions and processes of producing and using the compositions for the saccharification of lignocellulosic material.
2017/0204440 METHODS AND SYSTEMS FOR ENZYMATIC HYDROLYSIS OF PRETREATED BIOMASS AT HIGH SOLIDS CONCENTRATIONS
A method of enzymatically hydrolyzing pretreated lignocellulosic biomass at high solids concentration includes introducing pretreated biomass to a hydrolysis...
2017/0204439 Microorganism Having Improved L-Lysine Productivity and Method for Producing L-Lysine Using Same
Provided are a microorganism of the genus Corynebacterium having an enhanced activity to produce L-lysine as a result of inactivating a secretory protein and a...
2017/0204438 METHODS FOR PRODUCING 6-CARBON CHEMICALS VIA METHYL-ESTER SHIELDED CARBON CHAIN ELONGATION
This document describes biochemical pathways for producing adipic acid, 6-aminohexanoic acid, 6-hydroxhexanoic acid, hexamethylenediamine, caprolactam, or...
2017/0204437 PROCESS FOR PRODUCING PENTANOIC ACID AND HEPTANOIC ACID FROM ETHANOL AND PROPIONIC ACID
The present invention relates to a method of producing valeric acid, heptanoic acid, esters and/or salts thereof from a carbon source, the method comprising a...
2017/0204436 MICROBIAL PRODUCTION OF FATTY DIOLS
The disclosure relates to fatty diols and recombinant microorganisms for producing them. More particularly, the disclosure relates to recombinant ...
2017/0204435 Polypeptides Having Glucoamylase Activity and Polynucleotides Encoding Same
The present invention relates to isolated polypeptides having glucoamylase activity and isolated polynucleotides encoding the polypeptides. The invention also...
2017/0204434 Maximizing Production of Hydrogen From Waste Materials by Active Removal of Hydrogen
The present invention provides a method of producing hydrogen from a waste material, comprising steps of fermenting 100 a fermentation mixture comprising the...
2017/0204433 METHOD FOR RECONSTRUCTING A NON-HUMAN ANIMAL EMBRYO
The present invention refers to a method for reconstructing a non-human animal embryo, to a method for generating a nonhuman animal and to a non-human animal...
2017/0204432 METHODS FOR OPTIMIZING ELECTROPORATION
Embodiments of the invention are directed to a technique for electroporation that allows for a delivery of long electrical pulses of high magnitude in highly...
2017/0204431 PRODUCTION OF VIRAL VECTORS
The present invention relates to methods and compositions for the production of viral vectors. In particular, the present invention provides methods and...
2017/0204430 TARGETED MODIFICATION OF RAT GENOME
Compositions and methods are provided for modifying a rat genomic locus of interest using a large targeting vector (LTVEC) comprising various endogenous or...
2017/0204429 ACETYL-CoA CARBOXYLASE HERBICIDE RESISTANT SORGHUM
The present invention provides for compositions and methods for producing crop plants that are resistant to herbicides. In particular, the present invention...
2017/0204427 MODIFYING PROTEIN PRODUCTION IN PLANTS
A method for synthesizing a protein of interest within a plant or a portion of a plant is provided. The method involves treating the plant to increase...
2017/0204426 MODIFIED BRASSICA PLANTS WITH INCREASED SEED OIL CONTENT
Methods and means are provided to increase the seed oil content of Brassica plants by preventing feedback inhibition by phosphoenolpyruvate (PEP) of a...
2017/0204425 ENGINEERED ZINC FINGER PROTEINS TARGETING PLANT GENES INVOLVED IN FATTY ACID BIOSYNTHESIS
The present disclosure relates to engineered zinc finger proteins that target genes in plants involved in fatty acid biosynthesis. Methods of using such zinc...
2017/0204424 INDOLE-DERIVED COMPOUND PRODUCTION
Among the various aspects of the present disclosure is the provision of a transgenic organism, an artificial DNA construct, and methods for producing a...
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