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Patent # Description
2017/0204211 Method of Preparing a Zwitterionic Copolymer
A method for preparing a zwitterionic co-polymer comprising the steps of: a) providing a solution of at least one ethylenically unsaturated polymerizable...
2017/0204210 WATER-SOLUBLE HYDROXYALKYL POLYMER OBTAINED BY A METHOD OF INVERSE SUSPENSION OR INVERSE EMULSION POLYMERISATION
This invention relates to a water-soluble polymer in bead or powder form, characterized in that it has a Brookfield viscosity greater than 100 cps, and in that...
2017/0204209 REACTIVE MONOMERS AS COMONOMERS FOR THE PRODUCTION OF POLYMERS
The present invention relates to the use of reactive monomers as plasticizers in copolymers. The invention further relates to copolymers obtainable by using...
2017/0204208 Producing polyolefin products
Catalyst systems and methods for making and using the same are described herein. A catalyst system can include at least three catalysts. The three catalysts...
2017/0204207 Separation Vessels For Use In Polymerization Processes and Methods For Cleaning Same
Both a system and method for cleaning a low pressure separation vessel of a high pressure polyethylene polymerization plant are provided. The system includes a...
2017/0204206 ETHYLENE POLYMERIZATION PROCESS HAVING IMPROVED HEAT EXCHANGER PERFORMANCE
A process for the preparation of polyethylene by polymerizing in a slurry ethylene and optionally one or more C.sub.3 to C.sub.10 alpha-olefins in a reactor...
2017/0204205 MODIFIED STYRENE-BUTADIENE COPOLYMER, PREPARATION METHOD THEREOF, AND RUBBER COMPOSITION INCLUDING THE SAME
The present invention relates to a modified styrene-butadiene copolymer with a high modification ratio, including a functional group derived from a modifier...
2017/0204204 Processes For The Removal Of Rubber From Non-Hevea Plants
Provided herein are organic solvent-based processes for the removal of rubber from non-Hevea plants such as guayule shrubs. By the use of the processes, solid...
2017/0204203 POLY ALPHA-1,3-GLUCAN SOLUTION COMPOSITIONS
Solution compositions of poly alpha 1,3 glucan useful for making films and other formed objects are disclosed.
2017/0204202 Milling Process
The present invention provides process for treating crop kernels, comprising the steps of a) soaking kernels in water to produce soaked kernels; b) grinding...
2017/0204201 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS PRODUCED IN A CARBOXYLATED IONIC LIQUID PROCESS AND PRODUCTS...
This invention relates to novel compositions comprising regioselectively substituted cellulose esters. One aspect of the invention relates to processes for...
2017/0204200 MULTISPECIFIC ANTIBODY CONSTRUCTS
The present disclosure relates to a multi-specific antibody molecule comprising or consisting of: a) a polypeptide chain of formula (I): ...
2017/0204199 MODIFIED ANTIGEN BINDING POLYPEPTIDE CONSTRUCTS AND USES THEREOF
The present invention provides heterodimer pairs that can comprise a first heterodimer and a second heterodimer wherein each heterodimer comprises an...
2017/0204198 Antibodies to Aripiprazole Haptens and Use Thereof
Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The...
2017/0204197 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes
Disclosed herein are methods for treating type 2 diabetes, limiting development of type 2 diabetes, and treating a pre-diabetic state by administering to a...
2017/0204196 ANTI-NME ANTIBODY
The present application discloses anti-NME antibodies and their use in treating or preventing diseases.
2017/0204195 ANTI-FACTOR XI MONOCLONAL ANTIBODIES AND METHODS OF USE THEREOF
Compositions and methods for inhibiting thrombosis without compromising hemostasis are described. Compositions include anti-factor XI monoclonal antibodies...
2017/0204194 ANTI-CD3 ANTIBODIES AND METHODS OF USE
The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
2017/0204193 Antibody Fc Mutants with Ablated Effector Functions
Antibody and other Fc-containing molecules with variations in the Fc region reduce binding to Fc gamma receptors and resulting activity and can be used in the...
2017/0204192 HUMAN SERUM ALBUMIN LINKERS AND CONJUGATES THEREOF
Disclosed is a human serum albumin (HSA) linker and HSA linker with binding, diagnostic, and therapeutic agents conjugated thereto. Also disclosed is a...
2017/0204191 MUC1* ANTIBODIES
The present describes monoclonal antibody to MUC1*.
2017/0204190 ZCYTOR17 HETERODIMERIC CYTOKINE RECEPTOR MONOCLONAL ANTIBODIES
Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing...
2017/0204189 THERAPEUTIC METHOD AND MEDICAMENT FOR HTLV-1 ASSOCIATED MYELOPATHY
The object of the present invention is to provide a new therapeutic method and a new therapeutic agent that are different from known therapeutic medicines for...
2017/0204188 ANTI-FGFR3 ANTIBODIES AND METHODS USING SAME
The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
2017/0204187 METHODS OF TREATING AND PREVENTING CANCER DRUG RESISTANCE
Provided herein are combination therapies for the treatment of pathological conditions, such as cancer, using an antagonist of FGFR signaling and a B-raf...
2017/0204186 DEPLETION OF PLASMACYTOID DENDRITIC CELLS
The present invention relates to antibodies targeted to BDCA2 that deplete plasmacytoid dendritic cells (pDC) and methods of using the antibodies to treat...
2017/0204185 B7-H3 AND B7-H4, NOVEL IMMUNOREGULATORY MOLECULES
The invention provides novel B7-H3 and B7-H4 polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing...
2017/0204183 MOLECULES WITH SPECIFICITY FOR CD45 AND CD79
The present disclosure relates to a multispecific molecule comprising a binding domain specific to the antigen CD45 and a binding domain specific to the...
2017/0204182 VH-VL-INTERDOMAIN ANGLE BASED ANTIBODY HUMANIZATION
Herein is reported a method for selecting one or more variant antibody Fv fragments derived from a parent antibody Fv fragment comprising the steps of i)...
2017/0204181 ANTI-CD47 ANTIBODIES AND METHODS OF USE
Disclosed herein are anti-CD47 antibody molecules, their manufacture and use in treating disorders associated with CD47 expression, for example, certain...
2017/0204180 CD33 ANTIBODIES AND USE OF SAME TO TREAT CANCER
The invention provides murine, chimeric, and humanized antibodies that specifically hind to CD33. The antibodies are useful for treatment and diagnoses of...
2017/0204179 ANTI-ILT7 ANTIBODY
An antibody binding to IPC was obtained by using an animal cell in which a cell membrane protein associatable with ILT7 was co-expressed as an immunogen. The...
2017/0204178 MOLECULES WITH SPECIFICITY FOR CD79 AND CD22
The present disclosure relates to multispecific molecule comprising a binding domain specific to the antigen CD22 and a binding domain specific to the antigen...
2017/0204177 IMMUNOLOGIC EFFECTOR CELL OF TARGETED CLD18A2, AND PREPARATION METHOD AND USE THEREOF
Disclosed are a chimeric antigen receptor (CAR) targeting CLD18A2, and preparation method and use thereof. The extracellular binding region of the CAR...
2017/0204176 Tri-Specific Binding Molecules That Specifically Bind to Multiple Cancer Antigens and Methods of Use Thereof
The present invention relates to Tri-Specific Binding Molecules, which are multi-chain polypeptide molecules that possess three Binding Domains and are thus...
2017/0204175 ANTI-NOTCH2 NRR ANTIBODIES
The invention provides anti-Notch antibodies, and in particular, antibodies that bind Notch2 NRR, and methods of using the same.
2017/0204174 MONOCLONAL ANTIBODIES TO GROWTH AND DIFFERENTIATION FACTOR 15 (GDF-15), AND USES THEREOF FOR TREATING CANCER...
The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention...
2017/0204173 Antibodies to Alpha Synuclein
The application identifies novel fragments of alpha-synuclein in patients with Lewy Body Disease (LBD) and transgenic animal models thereof. These diseases are...
2017/0204172 MEDICAMENT AND APPARATUS FOR TREATING CHRONIC KIDNEY DISEASE
The present invention provides a novel therapy concept based on a removal of circulation BSP (bone sialoprotein) from the plasma of patients with chronic...
2017/0204171 ANTI-N3pGlu AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF
Antibodies to human N3pGlu A.beta., compositions comprising such N3pGlu A.beta. antibodies, and methods of using such N3pGlu A.beta. antibodies for the...
2017/0204170 ANTIBODY BASED REAGENT THAT SPECIFICALLY RECOGNIZES TOXIC OLIGOMERIC FORM OF BETA-AMYLOID
The invention relates to antibodies, antibody fragments and binding agents that specifically recognizes oligomeric A.beta. that is resistant to denaturation by...
2017/0204169 METHODS, COMPOSITIONS AND KITS FOR TREATING A SUBJECT USING A RECOMBINANT HETEROMULTIMERIC NEUTRALIZING BINDING...
Methods, compositions and kits are provided for treating a subject exposed to or at risk for exposure to a disease agent using a pharmaceutical composition...
2017/0204168 IMMUNOREACTIVE PROTEIN ORTHOLOGS OF EHRLICHIA CANIS AND E. CHAFFEENSIS
The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis. In particular, epitopes...
2017/0204167 NEUTRALIZING ANTI-INFLUENZA A VIRUS ANTIBODIES AND USES THEREOF
The invention relates to antibodies, and antigen binding fragments thereof, that specifically bind to an epitope in the stem region of an influenza A...
2017/0204166 THERAPY FOR FILOVIRUS INFECTION
The present invention addresses a need for improved treatments for filovirus infections. This invention provides an isolated humanized anti-filovirus...
2017/0204165 HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN CYTOMEGALOVIRUS (CMV) GB PROTEIN
Recombinant monoclonal antibodies to human cytomegalovirus (CMV) gB protein are described. The affinities of these antibodies are higher than the best...
2017/0204164 SYNTHETIC IMMUNOGLOBULIN DOMAINS WITH BINDING PROPERTIES ENGINEERED IN REGIONS OF THE MOLECULE DIFFERENT FROM...
Libraries of immunoglobulins which each have one or more amino acid modifications in at least one structural loop region of such immunoglobulins, where the...
2017/0204163 COMPOSITIONS COMPRISING RESURFACED CELL-PENETRATING NANOBODIES AND METHODS OF USE THEREOF
The disclosure encompasses resurfaced cell-penetrating nanobodies and their methods of use. The resurfacing of nanobodies with positively-charged amino acids...
2017/0204162 CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE
Degradable bioprostheses made of collagen-based material having amine-based and ester-based crosslinks are provided, as are methods for their formation and...
2017/0204161 FAST AND EFFICIENT CONJUGATION METHOD BASED ON THIOUREA-CATECHOL COUPLING
The present invention provides novel methods and compositions useful for a fast and efficient chemical conjugation method of making hetero-arm polymers based...
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