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Patent # Description
2017/0202857 17-HYDROXY-17-PENTAFLUOROETHYL-ESTRA-4,9(10)-DIEN-11-ARYL DERIVATIVES, METHOD OF PRODUCTION THEREOF AND USE...
The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of Formula I with progesterone antagonizing action and method of...
2017/0202856 TREATMENT OF ADRENAL INSUFFICIENCY
The disclosure relates to the treatment of adrenal insufficiency with particular but not limiting application to paediatric treatment regimens, the treatment...
2017/0202855 SOLID GANAXOLONE COMPOSITIONS AND METHODS FOR THE MAKING AND USE THEREOF
In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter...
2017/0202853 SUSTAINED RELEASE DELIVERY OF ACTIVE AGENTS TO TREAT GLAUCOMA AND OCULAR HYPERTENSION
A method of decreasing intraocular pressure (IOP) in an eye of a patient in need thereof includes implanting a first lacrimal implant through a firsts punctum...
2017/0202852 TOPICAL DOSAGE REGIMEN
Described herein is a novel dosage regimen, and related uses and methods, for a prostaglandin FP receptor agonist (PFPRA) compound topically administered to...
2017/0202851 PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Compounds of formula (I): ##STR00001## wherein A.sub.1, A.sub.2, R.sub.a, R.sub.b, R.sub.c, R.sub.d, R.sub.3, R.sub.4, R.sub.5 and T are as defined in the...
2017/0202850 OPHTHALMIC COMPOSITIONS OF RIFAMYCINS AND USES THEREOF
Provided herein are ophthalmic pharmaceutical formulations comprising a rifamycin compound. Also provided herein are methods of treating ocular diseases or...
2017/0202849 ANTIPARASITIC COMPOUNDS
The invention relates to 1,2,4-thiadiazole derivatives and their use to treat parasites.
2017/0202847 METHODS FOR THE TREATMENT OF TUMORS
The present invention is directed to methods of treating a tumor, in particular human tumors, including administering an effective amount of a MER tyrosine...
2017/0202846 1H-PYRAZOLO[3,4-B]PYRIDINES AND THERAPEUTIC USES THEREOF
Provided herein are compounds according to Formula I and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various...
2017/0202845 PROPHYLACTIC OR THERAPEUTIC AGENT FOR A POSTERIOR OCULAR DISEASE
Provided is a prophylactic or therapeutic agent for a posterior ocular disease, which comprises a compound represented by formula (1) below: ##STR00001## its...
2017/0202844 PEDIATRIC CHEWABLE TABLET CONTAINING ANTIVIRAL AGENT AND METHOD FOR THE PREPARATION THEREOF
The present invention relates to a pediatric chewable tablet comprising a therapeutically effective amount of an anti-viral agent or pharmaceutical acceptable...
2017/0202843 PEDIATRIC POWDER FOR ORAL SUSPENSION CONTAINING ANTIVIRAL AGENT AND METHOD FOR THE PREPARATION THEREOF
The present invention relates to a pediatric powder for reconstitution as suspension for oral administration comprising a therapeutically effective amount of...
2017/0202842 Method of Adjuvant Cancer Treatment
The present invention provides a method of providing adjuvant treatment to a human patient which comprises administering to such a patient therapeutically...
2017/0202841 QUINAZOLIN-4 (3H)-ONE DERIVATIVES USED AS P13 KINASE INHIBITORS
The present invention relates to the compound of formula (I) ##STR00001## and to compositions comprising the same and to the use of the compound and to...
2017/0202840 TREATMENT OF PANCREATIC CANCER WITH LIPOSOMAL IRINOTECAN
A liposome-encapsulated formulation of irinotecan can be used for the treatment of pancreatic cancer in combination with 5-fluorouracil and leucovorin,...
2017/0202839 Crystalline Form of Pemirolast
There is provided a hemihydrate form of the sodium salt of pemirolast.
2017/0202838 IMMUNOMODULATOR
This invention relates to an immunomodulator comprising, as an active ingredient, (S)--N-(4-amino-5-(quinolin-3-yl)-6,7,8,9-tetrahydropyrimido[5,4-b]indoli- ...
2017/0202837 PHARMACEUTICAL FORMULATIONS
This invention relates to solid oral pharmaceutical formulations or(S)-methyl ((4(4-(3-(5-chtoro-2-fluoro-3-(methyl-sutfonamido)phenyl)-1-isopropyl-1H-- ...
2017/0202835 OSMOLYTE-CONTAINING PREPARATION FOR THE TREATMENT OF DRY MUCOUS MEMBRANES
Osmolyte-containing preparations are provided for the local treatment of dry mucous membranes by enhancing mucus production. Included are the use of osmolytes...
2017/0202834 COMPOSITION FOR REDUCING NERVOUS SYSTEM INJURY AND METHOD OF MAKING AND USE THEREOF
This application discloses a composition comprising an amiloride and/or an amiloride analog which can be used for reducing nerve injury or nervous system...
2017/0202833 ORAL FORMULATION
Provided are an oral formulation capable of improving easy administrability and showing good preservation stability, and a substrate for oral formulation. An...
2017/0202832 USE OF METHYLNALTREXONE TO ATTENUATE TUMOR PROGRESSION
Presented herein are methods for preventing or treating tumor growth, tumor metastasis and/or abnormal proliferation of tumor cells in a subject, wherein the...
2017/0202831 Treating Pain In Patients With Hepatic Impairment
An extended release composition for an analgesic active pharmaceutical ingredient which may be an opioid, preferably hydrocodone as the only active ingredient....
2017/0202830 OXYMORPHONE TRANSDERMAL PATCH
The present invention relates to a transdermal patch comprising oxymorphone. The present invention also relates to processes for the preparation of the...
2017/0202829 Specific Akt3 Inhibitor and Uses Thereof Cross-Reference to Related Applications
Methods of selectively inhibiting Akt3 are provided. It has been discovered that 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide ...
2017/0202828 METHODS AND USES OF QUINOLINE DERIVATIVES IN THE TREATMENT OF SOFT TISSUE SARCOMAS AND PHARMACEUTICAL...
The present invention addresses methods and uses of quinoline derivatives in the treatment of tumours and pharmaceutical compositions for treatment of same....
2017/0202827 Method for Treatment of Primary Hormone Resistant Endometrial and Breast Cancers
The invention provides a method for treatment of primary progesterone receptor-negative (PR-) endometrial cancer comprising administering (i) cridanimod or a...
2017/0202825 APIXABAN FORMULATIONS
Compositions comprising crystalline apixaban particles having a D.sub.90 equal to or less than 89 .mu.m, and a pharmaceutically acceptable carrier, are...
2017/0202824 APIXABAN FORMULATIONS
Compositions comprising crystalline apixaban particles having a D.sub.90 equal to or less than 89 .mu.m, and a pharmaceutically acceptable carrier, are...
2017/0202823 METHOD OF TREATING CANCER USING SELECTIVE ESTROGEN RECEPTOR MODULATORS
Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor...
2017/0202822 METHODS AND COMPOSITIONS FOR ENHANCING CANCER THERAPY
The present invention provides methods and compositions for enhancing efficacy of anti-hormone treatment, or for preventing cancer relapse or progression...
2017/0202821 METHOD OF TREATING C3 GLOMERULOPATHY
Methods of treating a human suffering from or susceptible to C3 glomerulopathy comprising administering to the human an effective amount of a C5aR antagonist...
2017/0202820 SUBLINGUAL FENTANYL SPRAY
The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable...
2017/0202819 PHARMACEUTICAL COMPOSITIONS OF METABOTROPIC GLUTAMATE 5 RECEPTOR (MGLU5) ANTAGONISTS
Pharmaceutical compositions of metabotropic glutamate 5 receptor (mGlu5) antagonists or a pharmacologically acceptable salt thereof are disclosed. The...
2017/0202818 METHODS AND COMPOSITIONS TO MODIFY GSK-3 ACTIVITY
Methods for modulating GSK-3 activity and methods for treating a GSK-3-mediated disorder in a subject in need thereof. The methods include contacting a cell...
2017/0202817 DUAL DRUG DOSAGE FORMS WITH IMPROVED SEPARATION OF DRUGS
Drug tablets that include a prolonged-release core and an immediate-release layer or shell are prepared with a thin barrier layer of drug-free polymer between...
2017/0202815 5-FLUORO-N-(PYRIDIN-2-YL)PYRIDIN-2-AMINE DERIVATIVES CONTAINING A SULFOXIMINE GROUP
The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and...
2017/0202814 AGENTS FOR THE TREATMENT OF RETROVIRAL INFECTIOUS DISEASES
The invention relates to pyridine-3,5-bis-thiocyanates which are new active substances for the treatment and prevention of retroviral infections and secondary...
2017/0202813 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTIBACTERIAL AGENTS
A pharmaceutical compositions comprising: (a) a carbapenem antibacterial agent selected from imipenem, meropenem, ertapenem, doripenem or a pharmaceutically...
2017/0202812 COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES
The present invention relates to novel compounds and pharmaceutical compositions thereof which may be useful in the treatment and/or prevention of various...
2017/0202811 POROUS DOSAGE COMPOSITIONS AND METHODS OF PRODUCTION
The present invention provides a three-dimensionally printed porous dosage composition and a method of producing the same.
2017/0202810 SMALL MOLECULE INHIBITORS OF USP1 DEUBIQUITINATING ENZYME ACTIVITY
Provided are small molecule inhibitors of ubiquitin specific protease 1 (USP1) activity and methods for their use in treating and characterizing cancers. The...
2017/0202809 USE OF 3-(3-[1,2,4]-TRIAZOLO)-OXATRIAZOLIUM-5-OLATE FOR TREATING SEXUAL DISORDERS
The invention belongs to the chemical and pharmaceutical industry, including the creation of a new medicinal agent intended to treat sexual disorders, and can...
2017/0202808 PHARMACEUTICAL DOSAGE FORMS
The present invention relates to pharmaceutical dosage forms for oral administration comprising the drug substance ...
2017/0202807 RAPID DISPERSE DOSAGE FORM
A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of water soluble drug in a porous matrix that disperses in water...
2017/0202805 COMPOSITIONS AND METHODS FOR TREATING ALOPECIA
The present invention is directed to a composition for treating alopecia containing minoxidil, cyclosporine A and a compound that binds FK506 binding protein 4...
2017/0202804 WATER DISPERSIBLE MINI-TABLETS COMPRISING ENALAPRIL FOR TREATMENT OF HYPERTENSION IN A PEDIATRIC POPULATION...
The present invention relates to water dispersible mini-tablets of Enalapril or a pharmaceutically acceptable salt thereof for use in the treatment of...
2017/0202803 COMBINATION/ASSOCIATION OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE
Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical...
2017/0202802 COMPOSITIONS, KITS AND METHODS FOR NUTRITION SUPPLEMENTATION
Kits, compositions and methods are provided which comprise a nutritional composition and an adjuvant composition. The nutritional composition comprises vitamin...
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