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Patent # Description
2017/0226246 CATIONIC PARTICLES COMPRISING CYCLOPROPENIUM, THEIR PREPARATION AND USES
Embodiments of the present invention provides compounds, compositions, and methods for their preparation or synthesis that provide polymer-based cationic...
2017/0226245 COPOLYMER SUITABLE FOR IMPROVING HEAT RESISTANCE OF METHACRYLIC RESIN
Provided is a copolymer that has a heat resistance improvement effect, with respect to a methacrylic resin, superior to that of the prior art, while not...
2017/0226244 VERY LOW DENSITY POLYETHYLENE PRODUCED WITH SINGLE SITE CATALYST
Provided herein are VLDPE polymer compositions suitable for use in the manufacture of flexible films or sheets. In one embodiment, the copolymer comprises a...
2017/0226243 TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME
The present invention relates to tackifier compounds and methods of using the same. In various embodiments, the present invention provides a tackifier compound...
2017/0226242 CATALYST COMPOSITION FOR THE POLYMERIZATION OF OLEFINS
The invention relates to a catalyst composition for the polymerization of olefins, in which the catalyst is produced using a metal-containing compound having...
2017/0226241 CHROMIUM-BASED CATALYST COMPONENT COMPRISING A MODIFIED INORGANIC OXIDE SUPPORT
The present invention relates to a catalyst component comprising an inorganic oxide supported chromium, wherein said inorganic oxide support has been modified...
2017/0226240 Inert Stripping of Volatile Organic Compounds from Polymer Melts
A method of removing VOCs from a molten polymer comprising: (a) polymerizing monomers in a reactor to produce a reaction mixture comprising unreacted monomers...
2017/0226239 POLYMER WITH RELEASABLE GAS
Provided is a method of forming a polymer, comprising (a) providing a reaction mixture comprising (i) one or more vinyl monomers, (ii) one or more pH-sensitive...
2017/0226238 Process for Preparing a Halogenated Elastomer with Improved Mooney Viscosity Stability
This invention relates to a method of preparing a brominated elastomer having a stabilized Mooney viscosity. The method includes polymerizing isomonoolefins...
2017/0226237 METHOD FOR PRODUCING (METH)ACRYLIC RESIN COMPOSITION
A (meth)acrylic resin composition is obtained by a method comprising: continuously feeding a raw material solution essentially comprising methyl methacrylate,...
2017/0226236 METHOD FOR PREPARING DIENE-BASED RUBBER LATEX AND ACRYLONITRILE-BUTADIENE-STYRENE GRAFT COPOLYMER COMPRISING...
The present invention relates to a method for preparing large-sized diene-based rubber latex, and an acrylonitrile-butadiene-styrene graft copolymer comprising...
2017/0226235 BLOCK COPOLYMER
The present application relates to a monomer, a method for preparing a block copolymer, a block copolymer, and uses thereof. Each monomer of the present...
2017/0226234 VULCANIZING COMPOSITION CONTAINING CYCLODODECASULFUR AND IMPROVED CYCLODODECASULFUR COMPOUND
A vulcanizing composition useful for the vulcanization of vulcanizable formulations is disclosed. The vulcanizing composition includes a vulcanizing agent...
2017/0226233 PNEUMATIC TIRE
The present invention provides a pneumatic tire having well-improved rubber tensile strength and abrasion resistance while maintaining or improving good fuel...
2017/0226232 MODIFIED ALGINATES FOR ANTI-FIBROTIC MATERIALS AND APPLICATIONS
Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use...
2017/0226231 MICE THAT MAKE VL BINDING PROTEINS
Genetically modified mice and methods for making an using them are provided, wherein the mice comprise a replacement of all or substantially all immunoglobulin...
2017/0226230 ANTI-COMPLEMENT C1S ANTIBODIES AND USES THEREOF
The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. The present disclosure...
2017/0226229 ANTI-COMPLEMENT C1S ANTIBODIES AND USES THEREOF
The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. In some embodiments, such...
2017/0226228 Compositions and Methods to Regulate Renalase in the Treatment of Diseases and Disorders
The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase...
2017/0226227 Treatment of Leukemias and Chronic Myeloproliferative Diseases with Antibodies to EphA3
The invention provides methods and compositions comprising anti-EphA3 antibodies for the treatment of myeloproliferative disorders.
2017/0226226 Thrombin-Binding Antibody Molecules and Uses Thereof
This invention relates to isolated antibodies which recognise the exosite 1 epitope of thrombin and selectively inhibit thrombin without promoting bleeding....
2017/0226225 ANTI-COAGULATION FACTOR XI ANTIBODIES
Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
2017/0226224 PROTEIN PURIFICATION
A method for purifying a polypeptide by ion exchange chromatography is described which involves changing the conductivity and/or pH of buffers in order to...
2017/0226223 CHIMERIC ANTIGEN RECEPTOR COMPOSITIONS
Provided herein are compositions which exhibit novel diagnostic capabilities and allow to rapidly add functionality to adoptive immunotherapy. The compositions...
2017/0226222 BISPECIFIC ANTIBODY
Provided are bispecific antibodies comprised of a single-chain unit having specificity to an immune cell and a monovalent unit having specificity to a tumor...
2017/0226221 TUMOR ANTIGEN SPECIFIC ANTIBODIES AND TLR3 STIMULATION TO ENHANCE THE PERFORMANCE OF CHECKPOINT INTERFERENCE...
The present disclosure relates to a method for inhibiting cancer tumor growth in a patient by administering to the patient a therapeutic monoclonal antibody...
2017/0226220 METHOD OF TARGETING SPECIFIC CELL POPULATIONS USING CELL-BINDING AGENT MAYTANSINOID CONJUGATES LINKED VIA A...
The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or...
2017/0226219 DISEASE THERAPY BY INDUCING IMMUNE RESPONSE TO TROP-2 EXPRESSING CELLS
The present invention concerns compositions and methods of use of bispecific antibodies comprising at least one binding site for Trop-2 (EGP-1) and at least...
2017/0226218 Method for In Vivo Expansion of T Regulatory Cells
Compositions specific for TNF-receptor superfamily member 25 (TNFRSF25, DR3) modulate the immune response by regulating T regulatory cells.
2017/0226216 BCMA CHIMERIC ANTIGEN RECEPTORS
The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
2017/0226215 Antibody Therapeutics That Bind CD137
There is disclosed compositions and methods relating to or derived from anti-CD137 antibodies. More specifically, there is disclosed fully human antibodies...
2017/0226214 ANTIBODIES AGAINST G-CSFR AND USES THEREOF
The present disclosure provides proteins comprising antigen binding domains of antibodies that bind to human granulocyte-colony stimulating factor receptor.
2017/0226213 Human anti-FGFR4 antibody
The present invention relates to novel antibodies against the FGF receptor 4 (FGFR4) and to the medical use thereof, in particular for the diagnosis prevention...
2017/0226212 ANTI-VEGFR2 ANTIBODY THERAPY FOR HEPATOCELLULAR CARCINOMA
The invention provides for a human antibody that binds to human vascular endothelial growth factor receptor 2, preferably ramucirumab, for the treatment of...
2017/0226211 ANTI-CTLA-4 ANTIBODIES
Anti-CTLA-4 antibodies are disclosed. Also disclosed are compositions comprising such antibodies, and uses and methods using the same.
2017/0226210 Immunological Reagents
This disclosure relates to binding agents with specificity for programmed cell death 1 (PD-1) and to methods for using the same to treat, prevent and/or...
2017/0226209 AN ANTI-CD45RC ANTIBODY FOR USE AS DRUG
The invention relates to an isolated anti-CD45RC antibody for use in preventing or treating transplant rejection, autoimmune diseases, unwanted immune...
2017/0226208 NOVEL ANTIBODIES DIRECTED TO FC GAMMA RECEPTOR IIB AND FC EPSILON RECEPTOR
Disclosed herein are recognition molecules that bind with a first binding domain to the Fc epsilon receptor (Fc.epsilon.eR) and with a second binding domain to...
2017/0226207 NOVEL ANTI-HUMAN IgB ANTIBODY
[Problem] Provided is an anti-human Ig.beta. antibody which crosslinks BCR and Fc.gamma.RIIb and has an immunosuppressive function more enhanced than that of...
2017/0226206 Antibodies With Modified Affinity To FcRn That Promote Antigen Clearance
An objective of the present invention is to provide methods for facilitating antigen-binding molecule-mediated antigen uptake into cells, methods for...
2017/0226205 Therapeutic Use of Anti-CD22 Antibodies for Inducing Trogocytosis
Disclosed are methods and compositions of anti-B cell antibodies, preferably anti-CD22 antibodies, for diagnosis, prognosis and therapy of B-cell associated...
2017/0226204 CD7 NANOBODIES, ENCODING SEQUENCE AND USE THEREOF
Provided is a nanometer antibody for human CD7 molecule and an encoding DNA sequence thereof. The nanometer antibody can be efficiently expressed in...
2017/0226203 Anti-Orai1 Antibody
It is intended to provide a therapeutic and/or prophylactic agent for transplant rejections, immunological diseases, allergic diseases, inflammatory diseases,...
2017/0226202 METHOD FOR SCREENING FOR AUTOPHAGY ACTIVATOR OR INHIBITOR
The present invention provides a method for screening for an autophagy activator or inhibitor comprising the steps of: (a) making a test material to be...
2017/0226201 Methods of diagnosing and treating hyperproliferative disorders
The invention relates to compositions and methods for diagnosing and treating hyperproliferative disorders using ligands which specifically recognize the...
2017/0226200 Dual Variable Domain Immunoglobulins and Uses Thereof
Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are...
2017/0226199 ANTI-TNF ALPHA ANTIBODIES WITH PH-DEPENDEND ANTIGEN BINDING FOR IMPROVED TARGET CLEARENCE
The invention relates to anti-TNFa antibodies which are engineered to exhibit a pH-sensitive antigen binding. The invention is preferably directed to anti-TNFa...
2017/0226198 PREDICTING RESPONSE TO A VEGF ANTAGONIST
The invention describes the use of high CD31 and/or tumor VEGFA as selection criteria for determining patient benefit or responsiveness to a VEGF antagonist,...
2017/0226197 COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND MUSCLE STRENGTH BY SPECIFICALLY ANTAGONIZING GDF8 AND...
The present invention provides compositions and methods which involve specifically antagonizing GDF8 and Activin A. In certain embodiments, compositions are...
2017/0226196 ANTI-COLLAGEN ANTIBODIES FOR TREATMENT AND DIAGNOSIS
The invention relates to the diagnosis and treatment of diseases, including cancer and inflammatory disorders. The invention provides, and involves the use of,...
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