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Patent # Description
2017/0224670 Drug Combination to Treat Melanoma
This invention relates to the combination of vemurafenib and the heat shock protein 90 (HSP90) inhibitor XL888 to treat melanoma, particularly BRAF V600 mutant...
2017/0224669 HYDROALCOHOLIC SYSTEM FOR NAIL TREATMENT
A pharmaceutical composition related to drug delivery systems for the treatment of nail diseases includes (i) poloxamer 407, (ii) at least one penetration...
2017/0224668 OTAMIXABAN FORMULATIONS WITH IMPROVED STABILITY
The invention relates to a pharmaceutical composition comprising methyl (2R.3R)-2-{3-[amino(imino)methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzo- yl]amino}...
2017/0224667 CANCER CHEMOPREVENTIVE AGENT
Provided is a medicine for cancer chemoprevention, the medicine being characterized by containing, as an active ingredient, pirfenidone or a pharmaceutically...
2017/0224666 IMMEDIATE-RELEASE TABLET FORMULATIONS OF A THROMBIN RECEPTOR ANTAGONIST
Immediate-release formulations for oral administration of a thrombin receptor antagonist are provided. Certain formulations of higher API loading demonstrate...
2017/0224665 SELECTIVE HIGH AFFINITY ALFA3BETA4 NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS
Provided herein are novel and selective high affinity .alpha.3.beta.4 nicotinic acetycholine receptor ligands and pharmaceutical compositions thereof. In other...
2017/0224664 POWDER ORAL SUSPENSION FORMULATIONS OF ANTIBACTERIAL AGENTS
Powder oral suspension formulations of antibacterial compounds are described herein. In addition, reconstitutable powders of antibacterial compounds and oral...
2017/0224663 Methods of Use for Trisubstituted Benzotriazole Derivatives as Dihydroorotate Oxygenase Inhibitors
The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme...
2017/0224662 Aqueous Formulations and Methods of Preparation and Use Thereof
Provided herein are stable aqueous formulations of anesthetic compounds, suitable for injection or infusion.
2017/0224661 AMORPHOUS TECOVIRIMAT PREPARATION
Disclosed are methods for the preparation of amorphous N-[(3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-et- ...
2017/0224660 PROCESS FOR PREPARING ERTAPENEM-CONTAINING LYOPHILIZED FORMULATION
The present invention provides a process for preparing an ertapenem-containing lyophilized formulation, comprising the use of hydroxypropyl p-cyclodextrin as...
2017/0224659 A COMPOSITION HAVING A MUSCLE-RELAXANT AND ANTI-INFLAMMATORY ACTIVITY
A pharmaceutical composition or dietary supplement having a muscle-relaxant and anti-inflammatory activity is described, which is effective in the treatment of...
2017/0224658 Mono- or di-substituted indoles as dengue viral replication inhibitors
The present invention concerns mono- or di-substituted indole compounds of formula (I) which are useful to prevent or treat dengue viral infections and also...
2017/0224657 METHODS OF TREATING MUSCULAR DYSTROPHY
Disclosed herein are .alpha.7.beta.1 integrin modulatory agents and methods of using such to treat conditions associated with decreased .alpha.7.beta.1...
2017/0224656 A COMPOSITION FOR THE TREATMENT OF NEUROPATHIES AND/OR NEUROPATHIC PAIN
A pharmaceutical composition or dietary supplement is described that is effective in the treatment of neuropathies and/or neuropathic pain, comprising, as the...
2017/0224655 METHOD OF PREPARING DRUG AGGLOMERATE
A method of preparing drug agglomerates includes adding a drug powder to a first solvent to form a first solution, adding a second solvent to the first...
2017/0224654 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY
This disclosure provides methods and pharmaceutical compositions for reducing or eliminating cardiotoxicity, particularly cardiotoxicity induced by a cancer...
2017/0224653 TLR-INDEPENDENT SMALL MOLECULE ADJUVANTS
A TLR-independent adjuvant compound that corresponds in structure to Formula I, below, or its pharmaceutically acceptable salt is disclosed in ##STR00001## which...
2017/0224652 METHOD OF AMELIORATING UREMIA
A method of ameliorating symptoms of uremia includes administering a therapeutic agent including beraprost or each isomer constituting beraprost, or a salt...
2017/0224651 AROMATIC FARNESYL COMPOUND AND APPLICATION THEREOF
Aromatic farnesyl compound and application of a pharmaceutical salt thereof as an inhibitor of .alpha.-glucosidase, dipeptidyl peptidase-4, aldose reductase,...
2017/0224650 Methods for Making Compound Particles
Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a...
2017/0224649 METHOD FOR TREATING OVARIAN CANCER AND/OR HODGKIN LYMPHOMIA WITH A GOLD(III) COMPLEX
A method for treating cancer and gold(III) complexes with diaminocyclohexane ligand as anticancer agents. Also described are a pharmaceutical composition...
2017/0224648 PHORBOL ESTER COMPOSITIONS AND METHODS OF USE FOR TREATING OR REDUCING THE DURATION OF CYTOPENIA
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester in combination with G-CSF or in combination with EPO, are provided for...
2017/0224647 NEW MDR1 INHIBITORS FOR OVERCOMING MULTIDRUG RESISTANCE
New inhibitors of the activity of the multidrug resistance receptor 1 (MDR1), which are highly active to the MDR1 transporter, and showing a medium/high...
2017/0224646 COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISEASE
The present invention provides a method and composition for treating a neurodegenerative disease. In particular, the present invention provides a method and...
2017/0224645 MIXTURE OF FATTY ACIDS AND PALMITOYLETHANOLAMIDE FOR USE IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC PATHOLOGIES
The present invention relates to a mixture containing up to two fatty acids selected from palmitic acid, oleic acid, stearic acid, linoleic acid,...
2017/0224644 METHOD OF PRODUCING EGG YOLK BASED FUNCTIONAL FOOD PRODUCT AND PRODUCTS OBTAINABLE THEREBY
The present invention relates to the field of food products, especially food products specifically designed for providing health benefits beyond the basic...
2017/0224643 METHOD FOR AVOIDING OR INHIBITION OF DYSKINESIA
Certain neurological disorders are treated with dopamine agonists (e.g. L-Dopa) but these treatments unintentionally cause Levodopa-induced dyskinesias (LIDs)...
2017/0224642 Applicator-Based Transdermal Drug Delivery System for Administration of Drugs in Combination with Topical...
An applicator-based transdermal drug delivery system (ABTDS) for administration of drugs to a patient to treat ailments in combination with a wide range of...
2017/0224641 Methods and Compositions for Administration of 3-Halopyruvate and Related Compounds for the Treatment of Cancer
The present disclosure relates to the discovery that compounds of the invention, particularly 3-bromopyruvate and related compounds, can be safely administered...
2017/0224640 Compounds For Use In Treatment Of Mucositis
The present invention provides methods for treating and/or preventing mucostitis with one or more compounds, or pharmaceutically acceptable salts thereof,...
2017/0224639 4-HYDROXY TAMOXIFEN GEL FORMULATIONS
Pharmaceutical compositions comprising 4-hydroxy tamoxifen in an amount of 0.105-0.950% by weight effectively deliver the 4-hydroxy tamoxifen. Such...
2017/0224638 METHODS FOR THE TREATMENT OF TINNITUS INDUCED BY COCHLEAR EXCITOTOXICITY
The invention relates to methods for the prevention and/or treatment of tinnitus induced by cochlear excitotoxicity. In these methods, a pharmaceutical...
2017/0224637 INTRANSAL DELIVERY OF CURCUMIN
The present invention is directed to the intranasal delivery of curcumin adapted so as to target the brain.
2017/0224636 CURCUMIN-SOPHOROLIPID COMPLEX
The present invention relates to a complex comprising acidic sophorolipid and curcumin ((SL(A)+Cur), wherein, curcumin is solubilized and nano-encapsulated in...
2017/0224635 METHODS FOR TREATING ACUTE ACOUSTIC TRAUMA
The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The...
2017/0224634 STABLE CANNABINOID FORMULATIONS
The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
2017/0224633 HYDROXYTYROSOL AND OLEUROPEIN COMPOSITIONS FOR INDUCTION OF DNA DAMAGE, CELL DEATH AND LSD1 INHIBITION
Compositions comprising hydroxytyrosol-containing formulations and treatment regiments comprising hydroxytyrosol and/or oleuropein and chemotherapeutic agents...
2017/0224632 Microparticle Enabled Delivery Structures, Methods of Preparing and Using Same
The disclosed subject matter relates to the delivery of hydroxyl-containing compounds as microparticles for a variety of pharmaceutical, biomedical, cosmetics...
2017/0224631 MONOPOLYMER MULTIFUNCTIONAL SEQUENCED CAST POLYURETHANE MATRIX AND PRODUCTION THEREOF
The invention relates to a monopolymer multifunctional sequenced cast polyurethane matrix produced simply and efficiently, by sequentially pouring various...
2017/0224630 PATCH
A patch including: a support; and an adhesive layer disposed on at least one surface of the support, in which the adhesive layer includes: at least one...
2017/0224629 COMPOSITIONS FOR NAIL AND SKIN TREATMENT
Novel topical compositions for the treatment of nail and skin afflictions comprising at least one active agent, at least one volatile solvent, at least one...
2017/0224628 UNIFORM FILMS FOR RAPID DISSOLVE DOSAGE FORM INCORPORATING TASTE-MASKING COMPOSITIONS
The present invention relates to rapid dissolve thin film drug delivery compositions for the oral administration of active components. The active components...
2017/0224627 USE OF POLYMERIC EXCIPIENTS FOR LYOPHILIZATION OR FREEZING OF PARTICLES
Provided herein are use of polymeric excipients, specifically polyvinyl alcohols, optionally in conjunction with sugars, as cryoprotectants to prevent...
2017/0224626 ENTERIC-COATED HEMOGLOBIN MULTIPARTICULATE FOR ORAL DELIVERY OF HEMOGLOBIN BASED OXYGEN CARRIERS
The present invention provides an enteric-coated hemoglobin multiparticulate comprising a core, a hemoglobin formulation coating, an inner or sub-coating, and...
2017/0224625 REGULATED GENETIC SUICIDE MECHANISM COMPOSITIONS AND METHODS
Embodiments of the present invention relates to the incorporation and use of a regulated genetic suicide mechanism for use in the improved purification of...
2017/0224624 FORMULATIONS OF ENZALUTAMIDE
This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
2017/0224623 APPLICATION OF ANDROGRAPHOLIDE IN THE PREPARATION OF A PHARMACEUTICAL FOR TREATMENT OF INFLAMMATORY BOWEL...
The present invention relates to an andrographolide enteric targeting micropellet and method for preparation thereof; furthermore, the present invention also...
2017/0224622 APPLICATION OF ANDROGRAPHOLIDE IN THE PREPARATION OF A PHARMACEUTICAL FOR TREATMENT OF INFLAMMATORY BOWEL...
The present invention relates to an andrographolide enteric targeting micropellet and method for preparation thereof; furthermore, the present invention also...
2017/0224621 Compositions For Treating Acute, Post-Operative, Or Chronic Pain and Methods of Using the Same
Provided herein are compositions for treating acute, chronic, or post-operative pain in a subject, said compositions comprising an anticonvulsant agent and a...
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