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Patent # Description
2017/0258957 Medical Dressing
A medical dressing (30) is disclosed, comprising an adhesive layer (3) having a skin-facing surface (6) to adhere the medical dressing to a dermal surface,...
2017/0258956 Medical Dressing
A medical dressing is disclosed, comprising a substrate comprising a first chemical compound, said substrate having a first surface, wherein said medical...
2017/0258955 ABSORBENT ARTICLE WITH ACTIVATABLE MATERIAL
Material webs suitable for use in conjunction with disposable absorbent articles are disclosed herein. The material webs comprise a melt additive that when...
2017/0258954 FLOWABLE COLLAGEN-BASED HEMOSTAT AND METHODS OF USE
The invention relates to methods for fabricating a flowable hemostatic composition. The invention also relates to hemostatic compositions and methods for...
2017/0258953 ELECTRONEGATIVE FIBRE FOR USE IN THE HEALING OF WOUNDS
A subject of the present invention is a material comprising at least one electronegative fiber having a negative charge density of between 0.01 and 5 mmol/g...
2017/0258952 BODY FLUID DRAINAGE DEVICE AND METHOD
Method for sterilising a body fluid drainage system for handling a body fluid ex vivo. The body fluid drainage system comprises a chamber. The method comprises...
2017/0258951 STERILISATION CONTAINER, METHOD OF STERILISATION AND STERILISATION APPARATUS
Disclosed is a steam sterilizer, and a single use/disposable container for use in the steriliser and a sterilisation method. The container is a rigid or...
2017/0258950 LIPID STERILISATION METHOD
The present invention relates to a method for sterilisation of phospholipid suspensions, useful in the preparation of ultrasound contrast agent precursors...
2017/0258949 RADIOACTIVE COMPOSITIONS AND METHODS FOR THEIR THERAPEUTIC USE
This invention concerns a pharmaceutically-acceptable composition of radioactive metals, which are used for treating various diseases in animals or humans,...
2017/0258948 NOVEL PD-L1 BINDING POLYPEPTIDES FOR IMAGING
Provided herein are novel .sup.10Fn3 domains which specifically bind to PD-L1, as well as imaging agents based on the same for diagnostics.
2017/0258947 METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF
The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved...
2017/0258945 LANTHANIDE COMPLEX FORMULATIONS
The present invention relates to a method of removal of metal ion impurities, such as calcium, from lanthanide metal complexes of macrocyclic chelators. The...
2017/0258944 Formulations of Metal Complexes
The present invention relates to a method of preparation of formulations of gadolinium metal complexes of the macrocyclic chelator DOTA, which further comprise...
2017/0258943 Using Heavy Water as a Contrast Agent for Hydrogen Magnetic Resonance Imaging
A method of using an imaging contrast agent is provided for hydrogen magnetic resonance imaging (H MRI). The agent uses replacement and chemical exchange of...
2017/0258942 METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES
This invention relates to, in part, methods and compositions that are useful for the diagnosis, treatment, or prevention of a blinding eye disease, including...
2017/0258941 TOPICAL APPLICATION OF NERVE LABELING DYES FOR IMAGE-GUIDED SURGERY
The present invention relates to a topical agent that binds specifically to myelin basic protein and its method of use and determining myelination in the...
2017/0258940 TRANSGENIC MOUSE MODEL FOR CONDITIONAL FKBP51 EXPRESSION AND RELATED METHODS
The subject invention pertains to transgenic non-human animals comprising a transgenic nucleotide sequence, integrated into the genome of the animals,...
2017/0258939 Staining Composition
The invention is directed to a staining composition and to the use of the staining composition in staining ocular tissue. In a first aspect, the invention...
2017/0258938 EXOSOME TRANSFER OF NUCLEIC ACIDS TO CELLS
Methods for introducing nucleic acids to cells via exosomes for use in gene modulation and therapy, such as for gene silencing and to introduce genetic...
2017/0258937 PHARMACEUTICAL COMPOSITION, PREPARATION AND USES THEREOF
The invention relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle, said biocompatible...
2017/0258936 Tunable pH-Sensitive Linker for Controlled Drug Release
A novel acid labile linker for targeted delivery and/or controlled phosphoryl hydroxypropylglycine release of agents is introduced herein. There is further...
2017/0258935 COMPOUNDS AND METHODS FOR THE TREATMENT OF ERB B2/NEU POSITIVE DISEASES
Disclosed herein are anti-ERB B2/NEU antibodies conjugated with maytansinoid drugs for targeted delivery to disease tissues. Methods relating to the...
2017/0258934 PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES
The present disclosure relates to the use of antibody-drug conjugates (ADCs) comprising pyrrolobenzodiazepine (PBD) dimers and anti-CD25 antibodies for use in...
2017/0258933 COMPOSITIONS AND METHODS FOR THE DELIVERY OF MOLECULES INTO LIVE CELLS
The present disclosure provides methods and compositions related to the cytosolic delivery of proteins and cell-impermeable small molecules into live cells...
2017/0258932 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS
The invention described herein pertains to the diagnosis, imaging, and/or treatment of pathogenic cell populations. In particular, the invention described...
2017/0258931 STABLE PEPTIDE-CONJUGATED ASCORBIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION...
The present invention provides a stable peptide-conjugated, ascorbic acid derivative, a method for preparing the same, and a cosmetic composition comprising...
2017/0258930 SKIN PENETRATING PEPTIDES (SPPS) AND METHODS OF USE THEREFOR
The present disclosure provides peptides and peptide compositions, optionally in the from of a vaccine, which facilitate the delivery of an active agent or an...
2017/0258929 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES
The invention provides combinations and formulations including a luteinizing hormone-releasing hormone (LHRH) or a LHRH analog; and curcumin or a curcumin...
2017/0258928 CELL PENETRATING PEPTIDES FOR INTRACELLULAR DELIVERY OF MOLECULES
A cell-penetrating peptide characterized in that it comprises an amino acid sequence ...
2017/0258927 FORMULATIONS AND DOSES OF PEGYLATED URICASE
Provided herein are methods and compositions and kits related to uricase compositions and/or compositions comprising synthetic nanocarriers comprising an...
2017/0258926 MICELLAR NANOCOMPLEX
The present invention relates to micellar nanocomplexes and a method of forming the same. The micellar nanocomplex comprises a micelle and an agent...
2017/0258925 POLYMER-CONJUGATED METAP2 INHIBITORS, AND THERAPEUTIC METHODS OF USE THEREOF
One aspect of the invention provides polymer conjugated MetAP2 inhibitors. While not being bound by any particular theory, it is believed that coupling the...
2017/0258924 Ester of a Phospholipid With Conjugated Linoleic Acid for the Treatment of Psychiatric Disorders With...
An ester of a phospholipid with conjugated linoleic acid for use in the therapeutic treatment of or as a food supplement for psychiatric disorders with...
2017/0258923 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING
Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents....
2017/0258922 MICELLE CONTAINING EPIRUBICIN-COMPLEXED BLOCK COPOLYMER AND ANTI-CANCER AGENT, AND PHARMACEUTICAL COMPOSITION...
The problem addressed by the present invention is to develop a pharmaceutical having therapeutic efficacy against epirubicin-resistant tumors. The present...
2017/0258921 Protease Triggered Release Of Molecules From Hydrogels
The invention relates to compositions comprising (i) biocompatible hydrogel and (ii) one or more therapeutic agents contained within said hydrogel; wherein the...
2017/0258920 STABILIZER FOR HYALURONIDASE AND LIQUID FORMULATION COMPRISING HYALURONIDASE
This invention relates to a stable liquid formulation comprising hyaluronidase and a stabilizer for hyaluronidase and more particularly, to a stable liquid...
2017/0258919 Compositions
The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and...
2017/0258918 AERATED CONFECTIONARIES COMPRISING SHELF-STABLE ACTIVE INGREDIENTS
In one embodiment, a confectionary comprises at least one sweetener, at least one stabilizer, at least one emulsifier, water, a first active ingredient, and an...
2017/0258917 SOLUBILITY OF THERAPEUTIC AGENTS
Disclosed herein are methods and compositions to improve the solubility of therapeutic agents. In one embodiment, a method of improving solubility of a...
2017/0258916 Pharmaceutical Composition Containing Sympathomimetic Amine Salt and Co-distillable Additive
A pharmaceutical composition is provided which contains a water soluble acid salt of a sympathomimetic amine, e.g., pseudoephedrine, and an additive, e.g., a...
2017/0258915 Delivery and Formulation of Engineered Nucleic Acids
Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein...
2017/0258914 NOVEL ANTIFUNGAL COMPOSITION
There is provided a pharmaceutical composition for the treatment of fungal infection of the nail comprising a anti-fungal allylamine compound present in an...
2017/0258913 SHELF-STABLE FOAM-LIKE CONFECTIONARIES COMPRISING ERYTHRITOL AND ACTIVE INGREDIENTS
In one embodiment, a confectionary comprises 50 to 75 wt. % erythritol, 0 to 75 wt. % of at least one additional sweetener, at least one stabilizer, water, and...
2017/0258912 COMPOSITIONS AND METHODS FOR REDUCING OVERDOSE
Drug delivery formulations, uses thereof and methods of making same are provided in order to reduce the potential for abuse, misuse or improper administration...
2017/0258911 STABLE PHARMACEUTICAL FORMULATIONS OF METHYLNALTREXONE
Stable pharmaceutical compositions useful for administering methylnaltrexone are described, as are methods for making the same. Kits, including these...
2017/0258910 COMPOSITIONS AND METHODS FOR PROTECTING SAPONIN ACTIVITY
The invention is related to compositions including saponins and saponin-protective agents and related methods. In an embodiment, a composition is included...
2017/0258909 USE OF OPIOID ANTAGONISTS TO ATTENUATE ENDOTHELIAL CELL PROLIFERATION AND MIGRATION
The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation...
2017/0258908 METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS
Methods for the treatment of a cell proliferation disorder in a subject, involving: (1) administering to the subject at least one activatable pharmaceutical...
2017/0258907 MULTIMODE DEGRADABLE HYDROGELS FOR CONTROLLED RELEASE OF CARGO SUBSTANCES
A responsive hydrogel-based material may be used as a carrier system for the in situ delivery of various cargo substances, including bioactive moieties. The...
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