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Patent # Description
2017/0258906 VIRUS-PCION COMPLEX HAVING ENHANCED ANTITUMOR EFFECT BY USING ELECTROMAGNETIC FIELD
The present disclosure relates to a composition for transduction of a virus in a cell by using a crosslinked product of PEGylated magnetic nanoparticles and...
2017/0258905 METHODS AND COMPOSITIONS FOR ENHANCING THE POTENCY OF SUPERANTIGEN MEDIATED CANCER IMMUNOTHERAPY
The invention provides methods or compositions for enhancing the potency of a targeted cancer immunotherapy in a subject by using a superantigen in combination...
2017/0258904 Antagonism of the VIP Signaling Pathway
Inhibition of the VIP signaling pathway with VIP antagonist is contemplated. In certain embodiments, the disclosure relates to methods of enhancing the immune...
2017/0258903 COMBINATION THERAPIES FOR TREATING HER2-POSITIVE CANCERS THAT ARE RESISTANT TO HER2-TARGETED THERAPIES
Methods for treating cancer patients (e.g., cancer patients resistant or intolerant to pertuzumab and ado-trastuzumab emtansine) with HER2-positive tumors are...
2017/0258902 IMMUNOGENIC PEPTIDE CONJUGATE AND METHOD FOR INDUCING AN ANTI-INFLUENZA THERAPEUTIC ANTIBODY RESPONSE THEREWITH
Immunogenic influenza hemagglutinin-derived peptide conjugates described herein induce a specific therapeutic antibody response against influenza virus. The...
2017/0258901 LOCALIZED IMMUNOSUPPRESSION OF ALLOGRAFTS FOR PERIPHERAL NERVE REPAIR
Embodiments described herein relate to restorative solutions for segmental peripheral nerve (PN) defects using allografted PNs for stimulating PN repair. More...
2017/0258900 Immunostimulating Polyphosphazene Compounds
Polyphosphazene polymers having immunomodulating activity, and the biomedical use of such polyphosphazene polymers, in conjunction with an antigen or an...
2017/0258899 EMULSIFIED VACCINE TO OBTAIN FORMULATIONS OF CONCENTRATED IGY IMMUNOGLOBULINS; PROCESSES AND USES FOR THE SAME
The present invention relates to a therapy for treating or preventing several diseases in animals, based on the administration of a highly concentrated avian...
2017/0258898 VERSIKINE FOR INDUCING AND POTENTIATING AN IMMUNE RESPONSE
Disclosed are methods, kits, polypeptides, and pharmaceutical compositions for inducing an immune response in a subject, which may include a T-cell mediated...
2017/0258896 ENDOTOXIN NANOVESICLES: HYDROPHILIC GOLD NANODOTS CONTROL LIPOPOLYSACCHARIDE ASSEMBLY FOR MODULATING...
An endotoxin nanovesicle for enhancing type 1 T helper cell-induced immunological responses is disclosed. The endotoxin nanovesicle comprises: (a)...
2017/0258895 DNA-PEPTIDE COMBINATION VACCINE
The present invention provides a combination preparation for inducing a specific immune response to an antigenic peptide, which contains (I) the antigenic...
2017/0258894 NOVEL MUCOSAL VACCINATION APPROACH FOR HERPES SIMPLEX VIRUS TYPE-2
The invention provides methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. The protective...
2017/0258893 MERS-CoV Vaccine
Disclosed herein is a vaccine comprising a Middle East Respiratory Syndrome coronavirus (MERS-CoV) antigen. The antigen can be a consensus antigen. The...
2017/0258892 COMPOSITIONS AND METHODS TO TREAT AIDS
Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV are disclosed. The compositions and methods described herein...
2017/0258891 OPTIMIZED HIV ENVELOPE GENE AND EXPRESSION THEREOF
The present invention relates to a vector(s) containing and expressing an optimized HIV EnvF gene, methods for making the same and cell substrates qualified...
2017/0258890 GENETICALLY STABLE REPLICATION COMPETENT SENDAI VIRUS VECTOR(S) CONTAINING AND EXPRESSING OPTIMIZED HIV GENES
The present invention relates to genetically stable replication competent Sendai virus vector(s) containing optimized HIV genes, methods for making the same...
2017/0258889 COMPOSITIONS AND METHODS FOR STABILIZATION OF ACTIVE AGENTS
Provided herein are methods and compositions for stabilization of active agents. The active agents are distributed, mixed or embedded in a silk fibroin matrix,...
2017/0258888 INFLUENZA B VIRUS REPLICATION FOR VACCINE DEVELOPMENT
The invention provides a composition useful to prepare high titer influenza B viruses, e.g., in the absence of helper virus, which includes internal genes from...
2017/0258887 POLYSACCHARIDE COMPOSITION AND USE THEREOF
The present invention relates to the field of food or health care product, in particular a polysaccharide composition and use thereof. In the present...
2017/0258886 Production of an Immunogen Using a Plant Virus
Provided herein is a recombinant rod-shaped viral particle comprising a fusion protein comprising a coat protein for a rod-shaped plant virus and a epitope...
2017/0258885 FUSION PROTEIN COMPRISING STREPTOCOCCAL ANTIGEN
The disclosure provides a fusion protein comprising at least one antigenic fragment of a protein from a bacterium from genus Streptococcus, as well as means...
2017/0258884 Vaccine for Falciparum Malaria
The invention provides compositions and methods for preventing or reducing the severity of malaria.
2017/0258883 Protease-engineered Cancer Cell Spheres as an Immunotherapy to Treat Cancer and non-Cancer Diseases
Disclosed is a method of making a proteinase-engineered cancer vaccine or cancer-cell-derived spheres for treating a cancer patient, especially for cancer...
2017/0258882 CELL POPULATION FOR USE IN TRETING CANCER
The invention pertains to a cell population for use in treating cancer in a patient, comprising CD1c (BDCA-1).sup.+/CD19.sup.- dendritic cells, wherein...
2017/0258881 ANNEXIN A2 AS IMMUNOLOGICAL TARGET
AnnexinA2 (ANXA2), a member of the Annexin family of calcium-dependent, phospholipid binding proteins, is one of a panel of identified antigens recognized by...
2017/0258880 PEPTIDE CONJUGATED PARTICLES
The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles In particular, PLG particles...
2017/0258879 METHOD OF TREATING SEASONAL AFFECTIVE DISORDER
Methods are provided for treating or preventing seasonal affective disorder caused by the onset of a specific season in a subject. The method include...
2017/0258878 BLADDER INJECITON PARADIGM FOR ADMINISTRATION OF BOTULINUM TOXINS
Methods for treating a bladder dysfunction by injecting a clostridial derivative to a target site below the bladder midline are described.
2017/0258877 SYSTEMS AND METHODS FOR PREPARING A THROMBIN SERUM
A system for preparing a thrombin serum includes a containment device, a cage received within the containment device, a cap attachable to the containment...
2017/0258876 Viral Conjunctivitis Treatment Using Ranpirnase and/or Amphinase
The present specification discloses Ranpirnase and Amphinase, compositions comprising Ranpirnase and/or Amphinase, and methods and uses to treat a viral...
2017/0258875 AGENT FOR PREVENTING OR TREATING DEMYELINATING DISEASE
An object of the present invention is to provide a pharmaceutical preparation that can promote the proliferation of oligodendrocyte precursor cells to...
2017/0258874 FGF-8 FOR USE IN TREATING DISEASES OR DISORDERS OF ENERGY HOMEOSTASIS
The present invention relates to polypeptides for use in treating diseases or disorders of energy homeostasis such as obesity, dyslipidemia, diabetes, insulin...
2017/0258873 METHODS FOR DIAGNOSING, PROGNOSING AND TREATING MUSCULAR DYSTROPHY
Disclosed herein are methods for diagnosing, prognosing and treating muscular dystrophy. The disclosed methods can be used to diagnosis, prognosis or treat a...
2017/0258872 DPEP-1 BINDING COMPOSITIONS AND METHODS OF USE
Pharmaceutical compositions and methods of their use are provided for reducing inflammation in a subject, blocking leukocyte recruitment, inhibiting tumor...
2017/0258871 COMBINED USE OF A TRKA INHIBITOR AND AN EPHA2 INHIBITOR FOR USING IN THE TREATMENT OF SOLID CANCERS, AND METHOD...
The invention relates to an EphA2 inhibitor for the use thereof in the treatment of solid cancer treated with a TrkA inhibitor, and a TrkA inhibitor for the...
2017/0258870 LIMP-2 BASED PEPTIDES AND RELATED USES
Disclosed are LIMP-2 peptides, LIMP-2 polypeptides, variants thereof, and pharmaceutical compositions comprising the LIMP-2 peptides, LIMP-2 polypeptides, or...
2017/0258869 Pharmaceutical Compositions for Colon-Specific Delivery
Disclosed are pharmaceutical particulates which release a pharmaceutical compound into the colon following oral administration. A particulate comprises a core...
2017/0258868 Peptides for Inhibiting Angiogenesis
The present invention relates to peptides for inhibiting angiogenesis. The present invention also relates to methods of inhibiting angiogenesis and methods of...
2017/0258867 METHODS, AGENTS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATORY CONDITIONS
The present invention relates to the screening, diagnosis, prognostic evaluation, and treatment or prevention of age associated inflammation, chronic...
2017/0258866 MARINE PEPTIDES AND NUCLEOTIDES
Provided herein is a method of reducing postprandial concentrations of glucose in a subject's blood comprising administering to the subject, prior to or during...
2017/0258865 PHARMACEUTICAL COMPOSITION FOR TREATING OR ALLEVIATING AN AUTOIMMUNE DISEASE AND/OR COMPLICATION THEREOF AND/OR...
The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis,...
2017/0258864 COMPOSITION FOR THE PREVENTION AND/OR TREATMENT OF ALLERGY SYMPTOMS
The present invention relates to a pharmaceutical composition or a food supplement composition and use thereof in the prevention and/or treatment of allergy...
2017/0258863 THERMO-MODIFIED NUTSHELLS AND METHODS OF TREATING DIARRHEA, ADSORBING TOXINS, PROMOTING GROWTH AND IMPROVING...
Compositions comprising thermo-modified nutshells, for example hazelnut shells, are described herein. The compositions can also comprise one or more feed...
2017/0258862 COMPOSITIONS FOR THE TREATMENT OF AGE RELATED DISORDERS
The invention is directed to compositions for the prophylaxis, treatment and recovery of age related disorders. Compositions comprising a combination of parts...
2017/0258861 Treatment of Herpes, Pseudomonas, Staph, and Hepatitis
An improved method (process) is provided to treat herpes, pseudomonas, staphylococcus (staph), and hepatitis and help treat or alleviate cold sores, rashes,...
2017/0258860 THERAPEUTIC AND NUTRITIONAL COMPOSITIONS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
The present invention relates to nutritional compositions containing balanced amount of substance having anti-inflammatory activity, as curcumin, and substance...
2017/0258859 COMPOSITION FOR PREVENTING OR TREATING OSTEOARTHRITIS CONTAINING AN EXTRACT OF ANGELICA GIGAS NAKAI
Provided are a pharmaceutical composition for preventing and/or treating osteoarthritis comprising an extract of Angelica gigas Nakai, a pharmaceutical...
2017/0258858 NEW PROBIOTIC AND NEW BIOMARKER
The present invention relates to a new probiotic with immune modulating properties and to a new biomarker.
2017/0258857 Process for Producing a Soft Gel Capsule Comprising Viable Probiotic Bacteria and a Soft Gel Capsule Comprising...
The present invention provides a method for producing a soft gel capsule comprising uncoated probiotic bacteria, the method comprising gentle mixing the...
2017/0258856 LACTOBACILLUS RHAMNOSUS AND BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS FOR USE IN PREVENTION OR TREATMENT OF UPPER...
The present invention relates to a composition comprising Lactobacillus rhamnosus, preferably strain ATCC53103, and Bifidobacterium animalis subsp. lactis,...
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