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Patent # Description
2017/0260588 METHODS FOR DETECTING INACTIVATION OF THE HOMOLOGOUS RECOMBINATION PATHWAY (BRCA1/2) IN HUMAN TUMORS
The invention relates to methods for detecting inactivation of the DNA Homologous Recombination pathway in a patient, and in particular for detecting BRCA1...
2017/0260587 SQSTM1 MUTATIONS IN AMYOTROPHIC LATERAL SCLEROSIS
Provided herein is technology relating to diagnosing, monitoring, and treating disease and particularly, but not exclusively, to methods, compositions, and...
2017/0260586 GENE EXPRESSION MONITORING FOR RISK ASSESSMENT OF APPLE AND PEAR FRUIT STORAGE STRESS AND PHYSIOLOGICAL DISORDERS
The present invention is a tool for diagnosis and prediction using biomarker-based risk assessment for chilling-related disorders of Rosaceous fruit crops...
2017/0260585 DETECTION METHOD
The present invention relates generally to an array of nucleic acid molecules, the expression profiles of which characterise the anatomical origin of a cell or...
2017/0260584 CELL POPULATION ANALYSIS USING SINGLE NUCLEOTIDE POLYMORPHISMS FROM SINGLE CELL TRANSCRIPTOMES
The disclosure provides methods and systems for producing single cell RNA sequencing data. Single nucleotide polymorphisms (SNPs) identified in such data can...
2017/0260583 METHODS FOR VARIANT DETECTION
The invention can be used to provide a more efficient and less error-prone method of detecting variants in DNA, such as SNPs and indels. The invention also...
2017/0260582 HYBRID NANOPORE SENSORS
The disclosure provides detection apparatus having one or more nanopores, methods for making apparatus having one or more nanopore and methods for using...
2017/0260581 PRESERVATION OF INFORMATION RELATED TO GENOMIC DNA METHYLATION
The present invention relates to compositions, methods and systems for analyzing the methylation state of nucleic acids. Some embodiments relate to a...
2017/0260580 GENETIC DETECTION PLATFORM
Disclosed herein are methods, compositions, apparatus, systems and kits for performing polynucleotide amplification utilizing a pure polynucleotide polymerase....
2017/0260579 SEQUENCING REACTIONS WITH LITHIUM FOR PULSE WIDTH CONTROL
Compositions, kits, methods and systems for single molecule nucleotide sequencing comprising producing polymerase reactions having lithium that control the...
2017/0260578 METHOD FOR IMPROVING NUCLEIC ACID SYNTHESIS REACTION
Provided are the following: a method, for improving reactivity of an acid synthesis reaction, comprising a step for adding an .omega.-amino acid to a reaction...
2017/0260577 ARRAYS OF MICROPARTICLES AND METHODS OF PREPARATION THEREOF
This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be...
2017/0260576 TD PROBE AND ITS USES
The present invention relates to a target discriminative probe (TD probe) and its uses or applications. The TD probe is hybridized with a target nucleic acid...
2017/0260575 Devices and Methods Useful for Detecting Mechanical Forces of Ligand Receptor Interactions
This disclosure related to methods of detecting mechanical forces required to separate ligand and receptor interactions. In certain embodiments, this...
2017/0260574 Rapid Gene Sensors from Carbon Nanotube-DNA Systems
Methods, devices, and/or systems for providing carbon nanotube material that interacts with nucleotides to form CNT-nucleotide nanostructures wherein the...
2017/0260573 SPOT ARRAY SUBSTRATE, METHOD FOR PRODUCING SAME, AND NUCLEIC ACID POLYMER ANALYSIS METHOD AND DEVICE
In order to reduce the cost of producing a spot array substrate and reduce the cost of nucleic acid polymer analysis, a spot array substrate is used which is...
2017/0260572 DETECTION METHOD FOR NEISSERIA GONORRHOEAE
A method of detecting the presence of Neisseria gonorrhoeae in a sample. The method involves detecting a first target sequence taken from the NGO1642 gene...
2017/0260571 METHODS AND MATERIALS FOR TREATING ENDOMETRIAL CANCER
This document provides methods and materials for detecting and/or treating endometrial hyperplasia and/or endometrial cancer. For example, this document...
2017/0260570 ANTIBIOTIC RESISTANCE PROFILE FOR NEISSERIA GONORRHOEAE AND USE OF SAME IN DIAGNOSIS AND TREATMENT OF GONORRHEA
The present invention relates to an antibiotic resistance profile for Neisseria gonorrhoeae by assessing the presence of mutations (e.g., SNP) in antibiotic...
2017/0260569 PRESERVATION OF CELL-FREE NUCLEIC ACIDS
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic...
2017/0260568 Method For The Colorimetric Detection Of The Amplification Of A Target Nucleic Acid Sequence
The invention relates to methods and kits for the detection of the amplification of a target nucleic acid. The methods and kits of the invention are based on...
2017/0260567 Unitary Biochip Providing Sample-in to Results-out Processing and Methods of Manufacture
A biochip for the integration of all steps in a complex process from the insertion of a sample to the generation of a result, performed without operator...
2017/0260566 Analyte Detection on a Solid Support by Nucleic Acid Amplification Coupled to an Immunoassay
Embodiments of the invention provides a method for detection of at least one analyte derived from a sample, comprising the steps of: a) depositing the sample...
2017/0260565 PROPEPTIDE-LUCIFERASE FUSION PROTEINS AND METHODS OF USE THEREOF
The present invention provides nucleic acid constructs that encode fusion peptides comprising a bioluminescent protein and a precursor of a secreted peptide or...
2017/0260564 Method, System and Computer Program Product for Determining Microorganism Growth
A method for determining microorganism growth in a biological sample likely to contain microorganisms, said biological sample being contained in an analysis...
2017/0260563 TESTING TOXICITY OF A TEST SAMPLE
Invention describes a method and a device for testing toxicity of a test sample. The method comprises at least the steps of: providing an aliquot or a volume...
2017/0260562 PETRI DISH AND METHOD FOR THE MICROBIOLOGICAL EXAMINATION OF LIQUIDS BY MEMBRANE FILTRATION
The invention relates to a medium-filled Petri dish into which filters can be introduced particularly simply, and to a method for the microbiological...
2017/0260561 SYSTEM AND METHODS FOR DETECTING AND REMEDIATING MOLD
The present disclosure relates to systems for detecting, treating, comparing and testing for mold, mold spores and mold fragments physically present or in the...
2017/0260560 Amperometric Creatinine Biosensor With Immobilized Enzyme-Polymer Composition And Systems Using Same, And Methods
An amperometric biosensor is provided for determination of creatinine in a sample fluid. The biosensor can be an enzyme-polymer composition having at least one...
2017/0260559 FUNGAL HOST STRAINS , DNA CONSTRUCTS , AND METHODS OF USE
Provided are fungal host strains and recombinant DNA constructs for creation and use thereof, wherein the fungal host strains are particularly stable and...
2017/0260558 SYNTHESIS OF LONG NUCLEIC ACID SEQUENCES
The invention provides methods for the synthesis of long oligonucleotides, genes and gene fragments. The methods include the manufacture of genes or gene...
2017/0260557 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And An Organic Compound And Uses...
The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and an organic compound. The present invention...
2017/0260556 MICROORGANISM PRODUCING O-PHOSPHOSERINE AND A METHOD FOR PRODUCING O-PHOSPHOSERINE OR L-CYSTEINE USING THE SAME
The present invention relates to a microorganism, wherein the activity of a polypeptide capable of exporting O-phosphoserine (OPS) is enhanced, and a method of...
2017/0260555 METHOD FOR BIOSYNTHESIS OF ACETAMINOPHEN
The present disclosure provides methods for biosynthesis of acetaminophen. The present disclosure provides host cells genetically modified to provide for...
2017/0260553 Method of Producing Nylon
There is provided a method of producing aminohexanoic acid and/or aminohexanoic acid ester from synthesis gas, the method comprising: A. contacting the...
2017/0260552 Method of Producing Organic Compounds
There is provided a mixed culture of a first and second microorganism in an aqueous medium, wherein the first microorganism is an acetogenic microorganism...
2017/0260551 MICROORGANISMS AND METHODS FOR THE CO-PRODUCTION OF ETHYLENE GLYCOL AND THREE CARBON COMPOUNDS
The present application relates to recombinant microorganisms useful in the biosynthesis of monoethylene glycol (MEG) and one or more three-carbon compounds...
2017/0260550 LYASE AND METHOD FOR ASYMMETRIC SYNTHESIS OF (S)-PHENYLACETYLCARBINOL
A lyase has an amino acid sequence selected from SEQ ID NOs: 1, 2 and 3, wherein the amino acid isoleucine in position no. 468 in the protein ApPDC-E469G,...
2017/0260549 MODIFIED BACTERIA FOR THE PRODUCTION OF BIOALCOHOL
The present invention provides a modified bacterial strain capable of fermenting both hexose and pentose sugars for production of bioalcohol wherein a promoter...
2017/0260548 METHOD FOR PRODUCING ISOBUTENE FROM 3-METHYLCROTONYL-COA
Described is a method for the production of isobutene from 3-methylcrotonyl-CoA comprising the steps of: (a) enzymatically converting 3-methylcrotonyl-CoA into...
2017/0260547 METHODS AND COMPOSITIONS FOR GENE EDITING
Compositions and methods are provided for enhancing the efficiency of gene editing by timing the expression and activity of a nuclease to correspond with...
2017/0260546 TARGETED ELIMINATION OF BACTERIAL GENES
Provided is a kit or a system including two elements or components. The first component (i) is a selective component including a nucleic acid sequence and at...
2017/0260545 METHODS FOR PRODUCING PREPARATIONS OF RECOMBINANT AAV VIRIONS SUBSTANTIALLY FREE OF EMPTY CAPSIDS
Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography...
2017/0260544 Compositions and Methods for Modifying Cells
A method for engineering and utilizing large DNA vectors to target, via homologous recombination, and modify, in any desirable fashion, endogenous genes and...
2017/0260543 COMPOSITIONS AND METHODS FOR FLUORESCENT GENETIC BAR-CODING IN MAMMALIAN CELLS FOR ENHANCED MULTIPLEXING...
The invention provides cells or populations of cells, including non-human animals or non-human mammals having these cells, where the cells or populations of...
2017/0260542 BACTERIAL RESISTANT TRANSGENIC PLANTS HAVING DYSFUNCTIONAL T3SS PROTEINS
A nucleic acid expression vector comprising a nucleic acid sequence encoding a dominant negative T3SS protein is disclosed. The nucleic acid expression vector...
2017/0260541 PLANT REGULATORY ELEMENTS AND USES THEREOF
The invention provides recombinant DNA molecules and constructs, as well as their nucleotide sequences, useful for modulating gene expression in plants. The...
2017/0260540 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES
The present invention refers to a plant or plant part comprising a polynucleotide encoding a wildtype or mutated cellulose synthase (CESA) polypeptide, the...
2017/0260539 USE OF THE RD29 PROMOTER OR FRAGMENTS THEREOF FOR STRESS-INDUCIBLE EXPRESSION OF TRANSGENES IN COTTON
In one aspect, the present application discloses a chimeric gene comprising (a) a first nucleic acid sequence comprising at least 400 consecutive nucleotides...
2017/0260538 PLANT NITRATE TRANSPORTERS AND USES THEREOF
Methods and compositions that affect yield and other agronomic characteristics in plants are disclosed. Methods of transgenic modulation and marker-assisted...
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