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Patent # Description
2017/0274018 ARTIFICIAL CARTILAGE CONTAINING CHONDROCYTES OBTAINED FROM COSTAL CARTILAGE AND PREPARATION PROCESS THEREOF
The present invention relates to an artificial cartilage containing mesenchymal stem cell (MSC)-like dedifferentiated cells obtained by passage culturing...
2017/0274017 BONE FRACTURE HEALING WITH PRIMED DISTAL BONE MARROW MESENCHYMAL STROMAL CELLS
Methods, systems and activated human mesenchymal stromal cells (hMSCs) from bone marrow regions distal from bone fractures, the hMSCs enhanced for encouraging...
2017/0274016 METHODS FOR INCREASING OSTEOBLASTIC FUNCTION
The present disclosure provides methods of increasing osteoblastic function in a subject, the method comprising systemically administering to the subject a...
2017/0274015 PLATELET RICH PLASMA FORMULATIONS AND USE THEREOF
Compositions for platelet rich plasma (PRP) are provided. Generally, these compositions comprise a higher concentration of platelets than whole blood....
2017/0274014 COMBINATIONS OF LOW, IMMUNE ENHANCING, DOSES OF MTOR INHIBITORS AND CARS
The invention relates, in part, to a method of treating a subject comprising administering to the subject a low, immune enhancing of a mTOR inhibitor and an...
2017/0274013 WOUND FLUID ELEVATED PROTEASE ENZYME INHIBITION THROUGH CAMELID BLOOD PRODUCTS
Camelid blood products their peptide isolates and synthetic sequences for wound fluid elevated protease enzyme inhibition. The present invention provides...
2017/0274012 Acceleration of Reconstitution of Plasma Powder by Mixing with Small Beads
Methods of accelerating the reconstitution of plasma powder by mixing the powder with small beads is disclosed. The beads can be, for example, glass and/or...
2017/0274011 INJECTABLE SLURRIES AND METHODS OF MANUFACTURING AND USING THE SAME
One aspect of the invention provides a slurry comprising: a plurality of sterile ice particles having a largest cross-sectional dimension less than about 1.5...
2017/0274010 IMMUNE MODULATION USING PEPTIDES AND OTHER COMPOSITIONS
The present invention generally relates to compositions and methods for topical or transdermal delivery for immune modulation. In some cases, the composition...
2017/0274009 COMPOSITIONS AND METHODS TO AFFECT SKIN IRRITATION
Compositions are described that contain treated chitosan, modified chitosan and/or modified and treated chitosan for use in formulations for skin, hair and...
2017/0274008 Use of polysaccharide in Dendrobium officinale for anti-fatigue
The present invention relates to a glucomannan with a molecular size of 730 kDa, called DOP, which was previously identified as the unique authentication...
2017/0274007 PREBIOTIC INULIN BASED PREPARATION
The present invention relates to an inulin-based prebiotic complex enriched with vitamin B12 and selenium, which finds use in the field of food, nutraceutical,...
2017/0274006 NASAL COMPOSITION COMPRISING MIXTURE OF HYALURONIC ACIDS AND SALINE SOLUTION
The invention relates to a nasal composition comprising a saline base, an active agent and a mixture of a first hyaluronic acid having a molecular weight of at...
2017/0274005 TREATMENT OF RETINITIS PIGMENTOSA USING HYALURONIC ACID-CARBON NANOMATERIAL-PHOTOSENSITIZER COMPLEX
Disclosed is a complex for remedying or treating a retinal disease. The complex includes a hyaluronic acid or a derivative thereof, a carbon nanomaterial...
2017/0274004 TREATMENT OF CANCER USING TLR9 AGONIST WITH CHECKPOINT INHIBITORS
The invention provides methods of inducing an immune response to cancer comprising co-administering to a cancer patient one or more TLR9 agonists and one or...
2017/0274003 BLOCKING PIRB UPREGULATES SPINES AND FUNCTIONAL SYNAPSES TO UNLOCK VISUAL CORTICAL PLASTICITY AND FACILITATE...
Targeting and disrupting paired-immunoglobulin-like receptor B (PirB) function increases synaptic connectivity and plasticity even after the critical period,...
2017/0274002 MULTIPLE FOLATE FORMULATION AND USE THEREOF
A multiple folate composition comprising the following three different forms of folate: a folic acid (a salt or ester thereof); a folinic acid (a salt or ester...
2017/0274001 Compositions and Methods for Increasing Red Blood Cells
The invention relates generally to a composition and method for increasing the frequency, amount, or presence of red blood cells in peripheral blood. In one...
2017/0274000 TRIGGERING RNA INTERFERENCE WITH RNA-DNA AND DNA-RNA NANOPARTICLES
The instant invention provides RNA nanocubes, DNA nanocubes and R/DNA chimeric nanocubes comprising one or more functionalities. The multifunctional RNA...
2017/0273999 METHOD FOR PRODUCING SOLID DISPERSION CONTAINING HARDLY SOLUBLE POLYPHENOL
Provided is a method of producing a solid dispersion that can improve solubility of a hardly soluble polyphenol in water. Specifically, provided is a method of...
2017/0273998 COMPOSITIONS BASED ON SAFFRON FOR THE PREVENTION AND/OR TREATMENT OF CORNEAL DYSTROPHIES
The present invention relates to a pharmaceutical, dietary and/or food composition, comprising saffron for use in the prevention and/or treatment of corneal...
2017/0273997 PREBIOTICS FOR REDUCING THE RISK OF OBESITY LATER IN LIFE
The invention proposes a nutritional composition comprising selected oligosaccharides that reduces the abundance of Streptococcus bacteria in the gut of...
2017/0273996 Dosing Regimens for Treating And/Or Preventing Cerebral Amyloidoses
Described herein are dosing regimens and kits for the treatment and/or prevention of cerebral amyloidoses such as Alzheimer's disease (AD) and/or cerebral...
2017/0273995 ETHANOLAMINE-BASED LIPID BIOSYNTHETIC COMPOUNDS, METHOD OF MAKING AND USE THEREOF
A method for treating cancer is disclosed. The method comprises administering to a subject in need thereof, an effective amount of a pharmaceutical composition...
2017/0273994 Compositions and Methods for Combination Antiviral Therapy
The present invention relates to therapeutic combinations of [2-(6-amino-purin-9 yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester...
2017/0273993 PHARMACEUTICAL COMPOSITION CONTAINING GINKGOLIDE B AND BLOOD PLATELET PROSTAGLANDIN CYCLOOXYGENASE INHIBITOR...
Provided is a pharmaceutical composition containing ginkgolide B and the blood platelet prostaglandin cyclooxygenase inhibitor aspirin, a method for...
2017/0273992 PHARMACEUTICAL COMPOSITIONS FOR PREVENTING GLUCOCORTICOID-INDUCED CORNEAL OR SKIN THINNING
The present invention relates to method and pharmaceutical compositions for preventing glucocorticoid-induced corneal or skin thinning. In particular, the...
2017/0273991 TREATMENT OF CONGESTION USING STEROIDS AND ADRENERGICS
A decongestant composition is provided comprising: (a) a safe and effective amount of an adrenergic compound; (b) a safe and effective amount of a steroid; and...
2017/0273990 METHODS FOR THE SEPARATION AND DETECTION OF AN OXYSTEROL
Assay methods for determining purity of a sample of a sterol are provided. These methods include providing an HPLC eluent including a sterol, other compounds...
2017/0273989 PHARMACEUTICAL FORMULATIONS AND USES THEREOF IN THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION
The present invention relates to the use of a combination of a PDE5-inhibitor and testosterone for the preparation of a medicament for the treatment of Female...
2017/0273988 METHODS OF TREATING LYMPHOMA USING THIENOTRIAZOLODIAZEPINE COMPOUNDS
A method of treating lymphoma in a mammal comprises the step of: administering to a patient a pharmaceutical acceptable amount of a compound being a...
2017/0273987 Methods for Treating GI Syndrome and Graft versus Host Disease
We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing...
2017/0273986 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS
Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds ("diaminophenothiazinium compounds") including...
2017/0273985 TRICYCLIC DERIVATIVE
Disclosed are compounds useful as inhibitors of phosphodiesterase 1 (PDE1), compositions thereof, and methods of using the same. ##STR00001##
2017/0273984 COMPOSITION COMPRISING (6S)-5-METHYL TETRAHYDROFOLIC ACID OR SALT THEREOF, AND PREPARATION AND USE THEREOF
Disclosed are a composition including (6S)-5-methyl tetrahydrofolic acid or a salt thereof, and preparation and use thereof. In the composition, the content of...
2017/0273983 PYRROLOPYRIMIDINE COMPOUNDS USED AS TLR7 AGONIST
The present invention relates to a pyrrolopyrimidine compound as TLR7 agonist, and particularly relates to a compound of formula (I) or a pharmaceutically...
2017/0273982 PULSE DOSING REGIMEN AND METHODS OF TREATMENT
A novel dosing regimen for erlotinib or a pharmaceutically acceptable salt thereof is described herein. The dosing regimen demonstrates impressive control of...
2017/0273981 HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS
The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
2017/0273980 BENZYL SUBSTITUTED INDAZOLES AS BUB1 INHIBITORS
Compounds of formula (I) as defined herein and their use as pharmaceuticals. ##STR00001##
2017/0273979 NOVEL PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF URINARY INCONTINENCE
The problem to be solved by the present invention is to provide a novel pharmaceutical composition for prevention and/or treatment of urinary incontinence,...
2017/0273978 IMIDAZOYL ANILIDE DERIVATIVES AND METHODS OF USE
The present invention provides kinase inhibitor analogs with improved properties, such as improved efficacy, pharmacokinetics, safety, and specificity. In some...
2017/0273977 SUBSTITUTED 5-FLUORO-1H-PYRAZOLOPYRIDINES AND THEIR USE
The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations...
2017/0273976 6,7-DIHYDROPYRAZOLO[1,5-a]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2...
The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic...
2017/0273975 PHARMACEUTICAL COMPOSITION HAVING ABUSE DETERRENT PROPERTIES
An object of the present invention is to provide a pharmaceutical composition having abuse deterrent properties and thereby prevent the abuse of a...
2017/0273974 PATCH PREPARATIONS WITH MISUSE PREVENTION FEATURES
The present disclosure provides a patch preparation having features that prevent misuse. In some embodiments, a patch preparation containing a plaster on a...
2017/0273973 Novel Alpha-Hydroxy Carboxylic Acid and Derivatives and Other GRAS-Based Prodrugs of Oxymorphone and Uses Thereof
The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxymorphone, in a manner that substantially...
2017/0273972 HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS
The present invention provides heteroaryl ketone fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.
2017/0273971 Epimorphic Regeneration and Related Hydrogel Delivery Systems
Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a...
2017/0273970 Treatment and/or prophylaxis of TSPO mediated diseases and/or disorders
The invention relates to certain compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders that are, at least partially, mediated...
2017/0273969 Antidiabetic Solid Pharmaceutical Compositions
Provided are pharmaceutical compositions in solid form comprising a selective modulator of PPAR-.gamma. suitable for oral dosage to treat subjects having...
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