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Patent # Description
2017/0275642 NUCLEOTIDE SEQUENCES ENCODING FASCIATED EAR3 (FEA3) AND METHODS OF USE THEREOF
Methods and compositions for modulating shoot apical meristem size are provided. Methods are provided for modulating the expression of fea3 sequence in a host...
2017/0275641 COMPOSITIONS AND METHODS FOR IMPROVING ABIOTIC STRESS TOLERANCE
The present invention relates to compositions and methods for improving yield, yield stability, and/or drought stress tolerance in plants. Plants and/or plant...
2017/0275640 DOMINANT NEGATIVE MUTANT KRP PROTEIN PROTECTION OF ACTIVE CYCLIN-CDK COMPLEX INHIBITION BY WILD-TYPE KRP
Disclosed are mutant CDK inhibitor (CKI) polypeptides having dominant negative antagonist activity against wild-type CKI proteins, as well as related...
2017/0275639 PLANT-DERIVED ANTIBODIES AND DERIVATIVES THAT REDUCE RISK OF ANTIBODY-DEPENDENT ENHANCEMENT (ADE) OF INFECTION
The present invention describes the plant-based production of a therapeutic anti-virus antibody.
2017/0275638 ISOLATED POLYNUCLEOTIDES AND POLYPEPTIDES AND METHODS OF USING SAME FOR INCREASING PLANT UTILITY
Provided are isolated polypeptides comprising the amino acid sequence at least 80% homologous to SEQ ID NO:68, 51-66, 69-100, 379-656, 707-715, 720-723,...
2017/0275637 NOVEL MAIZE UBIQUITIN PROMOTERS
The Zea mays c.v. B73 Ubiquitin-1 (Z. mays c.v. B73 Ubi-1) promoter drives high levels of constitutive transgene expression in plants. Repeated use of the same...
2017/0275636 Methods and Vectors for Producing Transgenic Plants
Methods of, and compositions for, assembling one or more transcription units in a genome without a linked selectable marker or other unwanted transcription...
2017/0275635 INDUCIBLE PRODUCTION-PHASE PROMOTERS FOR COORDINATED HETEROLOGOUS EXPRESSION IN YEAST
Inducible promoters for the coordinated expression of at least one heterologous gene in yeast and methods of using them are disclosed. In particular, the...
2017/0275634 Protease Deficient Filamentous Fungal Cells and Methods of Use Thereof
The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.
2017/0275633 BIOLOGICAL INDICATOR
This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene...
2017/0275632 BIOLOGICAL INDICATOR
This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene...
2017/0275631 BIOLOGICAL INDICATOR
This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene...
2017/0275630 APTAMER CAPABLE OF BINDING TO HGF RECEPTOR
Provided is an aptamer including a polynucleotide of any of the following (a) to (c) and capable of binding to an HGF receptor to exhibit an activity of...
2017/0275629 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.
2017/0275628 ANTISENSE DESIGN
A novel class of pharmaceuticals which comprises a Locked Nucleic Acid (LNA) which can be used in antisense therapy. These novel oligonucleotides have improved...
2017/0275627 CHIMERIC SINGLE-STRANDED ANTISENSE POLYNUCLEOTIDES AND DOUBLE-STRANDED ANTISENSE AGENT
Chimeric single-stranded polynucleotides and double-stranded antisense agents useful for modifying the expression of a target gene by means of an antisense...
2017/0275626 MODIFIED DOUBLE-STRANDED RNA AGENTS
One aspect of the present invention relates to double-stranded RNA (dsRNA) agent capable of inhibiting the expression of a target gene. The sense strand of the...
2017/0275625 Methods Of Inhibiting Tumorigenesis In Colon Adenocarcinoma And Compositions Therefor
Described herein are methods and compositions for the treatment of colon cancers.
2017/0275624 Methods of Inducing Exon Skipping
Oligonucleotides for inducing exon skipping, including exon 51 of the dystrophin gene. Compositions are disclosed for treating Duchenne Muscular Dystrophy....
2017/0275623 CANCER TREATMENT AND IMMUNE SYSTEM REGULATION THROUGH FAT10 PATHWAY INHIBITION
Described herein are methods of inhibiting mitosis, treating cancer and/or treating immune disorders through the use of agents that inhibit FAT10 and/or the...
2017/0275622 ALTERATION OF NEURONAL GENE EXPRESSION BY SYNTHETIC piRNAs AND BY ALTERATION OF piRNA FUNCTION
Provided herein are compositions and methods for the alteration of neuronal methylation by synthetic piRNAs or by alteration of piRNA function. Such...
2017/0275621 CHIRAL CONTROL
The present invention relates to chirally controlled oligonucleotides, chirally controlled oligonucleotide compositions, and the method of making and using the...
2017/0275620 MODULATION OF APOLIPOPROTEIN C-III EXPRESSION
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to...
2017/0275619 COMPOSITIONS AND METHODS FOR TREATING VASCULAR DISORDERS
The present disclosure provides compositions and methods of their use to impair angiogenesis in a patient to treat indications including, but not limited to,...
2017/0275618 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF MYC BY DOUBLE-STRANDED RNA
This invention relates to compounds, compositions, and methods useful for reducing MYC target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate...
2017/0275617 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING LUPUS
The present disclosure provides methods for inhibiting and/or reducing self-reactive IgE and/or basophils, thereby treating or preventing lupus, lupus...
2017/0275616 PRIMER FOR NUCLEIC ACID RANDOM FRAGMENTATION AND NUCLEIC ACID RANDOM FRAGMENTATION METHOD
The present invention provides a primer for nucleic acid random fragmentation and a nucleic acid random fragmentation method. The primer consists of a...
2017/0275615 METHODS AND COMPOSITIONS FOR TREATING LEBER CONGENITAL AMAUROSIS
Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the...
2017/0275614 DEVICE FOR NUCLEIC ACID EXTRACTION USING MAGNETIC BEAD METHOD
The present invention provides a device for nucleic acid extraction using a magnetic bead method. The device includes a disc turntable, an arc arch bridge...
2017/0275613 METHOD AND APPARATUS FOR ENRICHING PATHOGEN DNA
A method and apparatus for enrichment and detection of low abundance pathogens are provided. The method includes adding one or more proteins containing...
2017/0275612 APPARATUS AND METHOD FOR EXTRACTING MICROBIAL CELLS
Methods and devices are provided for pre-treatment of a sample containing microbial cells. In some embodiments, the pre-treatment of the sample is performed...
2017/0275611 METHODS, CELLS & ORGANISMS
The invention relates to an approach for introducing one or more desired insertions and/or deletions of known sizes into one or more predefined locations in a...
2017/0275610 PROCESS FOR SEPARATION OF OLIGONUCLEOTIDE OF INTEREST FROM A MIXTURE
A method for separation of an oligonucleotide from a mixture using a biphasic mobile phase/stationary phase liquid-liquid chromatography system. A first mobile...
2017/0275609 Isolated oligonucleotide and use thereof in nucleic acid sequencing
Provided are an isolated oligonucleotide and a use thereof in nucleic acid sequencing, wherein the isolated oligonucleotide comprises a first strand, wherein...
2017/0275608 USE OF GALERINA MARGINATA GENES AND PROTEINS FOR PEPTIDE PRODUCTION
The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in...
2017/0275607 CARRIER FOR TARGETING NERVE CELLS
The present invention relates to a transport protein which can be obtained by modifying the heavy chain of the neurotoxin formed by Clostridium botulinum...
2017/0275606 THERMOSTABLE CELLOBIOHYDROLASE
A thermostable cellobiohydrolase, having a cellulose-binding motif domain including (A1) a polypeptide including an amino acid sequence represented by SEQ ID...
2017/0275605 THERMOSTABLE CELLOBIOHYDROLASE
A thermostable cellobiohydrolase, having a cellobiohydrolase catalytic domain including: (A) a polypeptide including the amino acid sequence represented by SEQ...
2017/0275604 Polypeptides Having Beta-Xylosidase Activity and Polynucleotides Encoding Same
The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also...
2017/0275603 Anti-Inflammatory Peptides and Composition Comprising the Same
The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises any one amino acid sequence of SEQ ID NO:1 to SEQ ID...
2017/0275602 Polymerases
Modified DNA polymerases have an affinity for DNA such that the polymerase has an ability to incorporate one or more nucleotides into a plurality of separate...
2017/0275601 RECOMBINASE MUTANTS
Presented herein are recombinases for improved recombinase-mediated amplification of nucleic acids, such as a PCR-library having single-stranded adapter...
2017/0275599 PLANT CELLS AND PLANTS EXPRESSING FUCOSYL TRANSFERASE FOR ANIMAL-TYPE SUGAR CHAIN ADDING FUNCTION
A plant cell having an animal-type sugar chain adding function is provided. The plant cell has an introduced gene encoding an enzyme derived from an animal,...
2017/0275598 NOVEL P450-BM3 VARIANTS WITH IMPROVED ACTIVITY
The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a...
2017/0275597 PHENAZINE DEGRADING AGENTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS FOR INTERFERING WITH VIABILITY OF BACTERIA
Provided herein are phenazine degrading agents, methods and systems for interfering with viability of bacteria and related antimicrobial and compositions.
2017/0275596 COMPOSITION AND METHOD FOR TREATING ANDROGEN-DEPENDENT DISORDERS
Chimeric polypeptides comprising a dihydrotestosterone (DHT) reductase moiety, such as 3 alpha-hydroxysteroid dehydrogenase (3.alpha.-HSD), fused to a signal...
2017/0275595 Bionanomaterials and Their Synthesis
The use of biomaterials, such as viruses and virus-like particles, to form nanostructures is generally disclosed. For instance, rod-like viruses can be used to...
2017/0275594 METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS USING SYNTHETIC PEPTIDE
Provided is a method of preparing induced pluripotent stem cells using a synthetic peptide, and more particularly, to a method of preparing induced pluripotent...
2017/0275593 MEDIA FOR CULTURING PLURIPOTENT STEM CELLS
A culture medium is disclosed which comprises STAT3 activator, an ERK1/2 inhibitor and an Axin stabilizer, and optionally also a PKC inhibitor. Cell cultures...
2017/0275592 CULTURE MEDIUM
The invention relates to improved culture methods for expanding epithelial stem cells and obtaining organoids, to culture media involved in said methods, and...
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