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Patent # Description
2017/0283405 PYRAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS
The present invention relates to compounds of formula I ##STR00001## wherein P is selected from P1 and P2, or P and R.sup.5 together are P3 ##STR00002## or P is...
2017/0283404 CRYSTALLINE FORMS OF 2-(4-(4-ETHOXY-6-OXO-1,6-DIHYDROPYRIDIN-3-YL)-2-FLUOROPHENYL)-N-(5-(1,1,1- ...
Disclosed are novel crystalline forms of 2-(4-(4-ethoxy-6-oxo-1,6-dihydropyridin-3-yl)-2-fluorophenyl)-N-(5-(1,1,1- ...
2017/0283403 DIAMIDE MACROCYCLES THAT ARE FXIA INHIBITORS
The present invention provides compounds of Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables...
2017/0283402 Poly(ADP-Ribose) Polymerase 1 Inhibitors Structurally Unrelated to NAD
Compounds that are not related to NAD, and which target PARP1-histone H4 interaction are provided, as well as compositions of these compounds, and methods for...
2017/0283401 THERAPEUTIC COMPOSITIONS AND RELATED METHODS OF USE
Compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that...
2017/0283400 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF
Provided herein are various compounds, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, useful for inhibiting arginine...
2017/0283399 Crystalline Forms of 6-((6,7-Dimethoxyquinazolin-4-yl)oxy)-N,2-Dimethylbenzofuran-3-Carboxamid- e
The present invention relates to the pharmaceutical field, provides novel crystalline forms, solvates and the crystalline forms thereof of compound ...
2017/0283398 2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Disclosed are a 2-aminopyrimidine compound and pharmaceutical composition and use thereof. The structure of the 2-aminopyrimidine compound is as represented by...
2017/0283397 SUBSTITUTED 1-H-INDOL-3-YL-BENZAMIDE AND 1, 1'-BIPHENYL ANALOGS AS HISTONE DEMETHYLASE INHIBITORS
Substituted 1-H-indol-3-yl-benzamide and 1, 1'-biphenyl analogs derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific...
2017/0283396 DIAMINOHETEROARYL SUBSTITUTED INDAZOLES
Compounds of formula (I) which are inhibitors of Bub 1 kinase, processes for their production and their use as pharmaceuticals.
2017/0283395 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
Chemical entities that are quinoxaline kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
2017/0283394 NOVEL INTERMEDIATE AND PROCESS USEFUL IN THE PREPARATION OF -(2-CHLOROPHENYL)-METHANONE
The present invention relates to novel compounds, (2-chlorophenyl)-[2-(2-hydroxy-2-pyridin-4-yl-vinyl)pyridin-3-yl]methanon- e benzoate, and ...
2017/0283393 Bruton's Tyrosine Kinase Inhibitors
Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (BTK). Methods for the preparation of the compounds are disclosed. Also...
2017/0283392 DIBENZAZEPINE DERIVATIVES AND USE THEREOF
The present disclosure provides dibenzazepine derivatives having Formula I or I(A): ##STR00001## and the pharmaceutically acceptable salts and solvates thereof,...
2017/0283391 CHIRAL SEPARATION OF delta8-THC, delta9-THC, AND RELATED ENANTIOMERS USING CO2-BASED CHROMATOGRAPHY
The present disclosure generally relates to methods for separating .DELTA..sup.8-THC, .DELTA..sup.9-THC, and related enantiomers using CO.sub.2-based...
2017/0283390 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS
The present disclosure provides processes for the preparation of a compound of formula: ##STR00001## which is useful as an antiviral agent. The disclosure also...
2017/0283389 Synthesis of Isoflavanes and Intermediates Thereof
Subject of the invention is a method for enantioselective production of an isoflavane from an isoflavone, comprising the steps: (a) selectively reducing the...
2017/0283388 14-HYDROXY-DOCOSAHEXAENOIC ACID COMPOUNDS
The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogues, their preparation, isolation, identification, purification and uses thereof.
2017/0283387 METABOLISM PROBES FOR THERAPY AND DIAGNOSIS
Novel 2-substituted glutamylanides useful as modulators of ASCT2 inhibitors. Compounds of the present invention can be used to treat patients suffering from...
2017/0283386 NOVEL AMINOALKYLBENZOTHIAZEPINE DERIVATIVES AND USES THEREOF
The present invention relates to a novel aminoalkylbenzothiazepine derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition...
2017/0283385 Proxisome Proliferator Activated Receptor (PPAR) Compounds and Methods of Using the Same
Peroxisome proliferator activated receptor (PPAR) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic...
2017/0283384 PSMA TARGETED FLUORESCENT AGENTS FOR IMAGE GUIDED SURGERY
Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain,...
2017/0283383 PRODUCTION METHOD OF 1, 2, 4-TRIAZOLE COMPOUND
A method for producing a 1,2,4-triazole compound involves reacting an amide compound represented by formula (2) with a hydrazide compound represented by...
2017/0283382 METHOD FOR PRODUCING PURE L-HERCYNINE
The invention relates to a method for the purification of L-hercynine. Said method for the purification of L-hercynine, from a reaction mixture resulting from...
2017/0283381 DIHYDROPYRIDINONE MGAT2 INHIBITORS
The present invention provides compounds of Formula (I): ##STR00001## or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the...
2017/0283380 Intermediate for Synthesizing Paroxetine, Method for Preparing the same, and Uses Thereof
A paroxetine intermediate, a method for preparing the same, and uses thereof are provided. Specifically, the method includes: reacting a compound of formula I...
2017/0283379 NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME (AS AMENDED)
The present specification provides a multicyclic compound including nitrogen and an organic light emitting device using the same.
2017/0283378 INDOLE DERIVATIVES FOR THE PREVENTION AND/OR TREATMENT OF DIABETES AND ASSOCIATED METABOLIC DISORDERS
The invention relates to substituted heterocyclic indole derivatives of Formula (I), which act as activators of the AMP-activated protein kinase (AMPK) and to...
2017/0283377 ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE
Compounds having a structure of Structure I: ##STR00001## or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R.sup.1, R.sup.2,...
2017/0283376 SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS
The present invention is directed to novel compounds of formula (I) and their use in treating and/or preventing metabolic diseases. ##STR00001##
2017/0283375 ABSCISIC ACID DERIVATIVE
The compound represented by formula (IV) or a salt thereof has an inhibitory action on an abscisic acid receptor. The compound or the salt thereof can be used...
2017/0283374 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA
Disclosed herein are 1,4-naphthoquinone analogs, pharmaceutical compositions that include one or more of such 1,4-naphthoquinone analogs, and methods of...
2017/0283373 Acid Mist Mitigation Agents for Electrolyte Solutions
Sulfonate-, sulfate-, or carboxylate-capped, alkoxylated anti-misting agents having the stricture: R(AO).sub.nX).sub.m((AO).sub.nH).sub.p, and methods of...
2017/0283372 PROCESS FOR PRODUCING HIGH-PURITY AQUEOUS UREA SOLUTION IN UREA PRODUCTION PROCESS
The present invention relates to a method for producing a high-purity aqueous urea solution, utilizing a urea production process at least including a urea...
2017/0283371 PROCESS FOR PRODUCTION OF AMMONIA AND DERIVATIVES, IN PARTICULAR UREA
A process for producing ammonia and a derivative of ammonia from a natural gas feed comprising conversion of natural gas into a make-up synthesis gas;...
2017/0283370 METHOD FOR PRODUCING 1,5-PENTANEDIISOCYANATE IN THE GAS PHASE
The invention relates to a method for producing 1,5-pentanediisocyanate (PDI) by reacting 1,5-pentanediamine (PDA) with phosgene in the gas phase.
2017/0283369 METHOD FOR CONTINUOUS PRODUCTION OF ADIPONITRILE
A process for the continuous preparation of adiponitrile by hydrocyanation of 3-pentenenitrile is described, wherein a) 3-pentenenitrile is hydrocyanated to...
2017/0283368 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS
Methods of synthesizing substituted tetracycline compounds are provided.
2017/0283367 NOVEL LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS
Compounds are provided having the following structure: ##STR00001## or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R.sup.1a,...
2017/0283366 Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives
The present invention benzoquinone derivatives of the formula (I): ##STR00001## and to pharmaceutically acceptable salts or solvates thereof. In formula (I) one...
2017/0283365 NITROGEN CONTAINING HYDROFLUOROETHERS AND METHODS OF USING SAME
A hydrofluoroether compound is represented by the following general formula (1): wherein n is 1-2. ##STR00001##
2017/0283364 METHOD FOR PREPARING ALPHA-HYDROXYCARBOXYLIC ACID ESTERS IN WHICH AMMONIA IS RECYCLED
The present invention relates to a process for preparing alpha-hydroxycarboxylic esters proceeding from hydrogen cyanide, wherein the ammonia formed in the...
2017/0283363 METHOD FOR PRODUCING DIESTERS OF TEREPHTHALIC ACID
The present invention relates to a process for preparing a terephthalic diester by reacting terephthalic acid with at least one alcohol, wherein terephthalic...
2017/0283362 Process For The Production Of Dialkyl Succinate From Maleic Anyhdride
In a process for the production of dialkyl succinate from a feedstock comprising maleic anhydride, feed in the liquid phase is provided to a reactor operated...
2017/0283361 A SINGLE STEP PROCESS FOR THE PREPARATION OF BUTYL ACETATE
The present invention discloses a single step, environmentally and economical viable process for the preparation of butyl acetate from ethyl acetate and...
2017/0283360 CLEAN PROCESS FOR PREPARING CHLOROFORMYL-SUBSTITUTED BENZENE
Clean process for preparing a chloroformyl-substituted benzene by oxidation of a tail gas hydrogen chloride from a chlorination reaction and a chloroacylation...
2017/0283359 PROCESS FOR LARGE SCALE PRODUCTION OF 1-ISOPROPYL-3--1H-INDAZOLE OXALATE
The present invention relates to a process suitable for adoption to large scale manufacture of ...
2017/0283358 (METH)ACRYLIC ACID PRODUCTION PROCESS
The invention relates to the production of (meth)acrylic acid, and to implementation of a step of condensing water contained in a recycled gas effluent and/or...
2017/0283357 ACRYLIC ACID PRODUCTION EQUIPMENT, METHOD FOR PRODUCING ACRYLIC ACID, AND METHOD FOR STOPPING PRODUCTION OF...
The present invention relates to an acrylic acid production equipment which includes a raw material gasification apparatus for converting liquefied propylene...
2017/0283356 Methods for the Production of alpha, beta-Unsaturated Carboxylic Acids and Salts Thereof
Processes for producing an .alpha.,.beta.-unsaturated carboxylic acid, such as acrylic acid, or a salt thereof, using treated solid oxides are disclosed. The...
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