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Patent # Description
2017/0281783 LOW PROTEIN PERCENTAGE GELLING COMPOSITIONS
Described herein are low protein concentration gelling compositions comprising keratin proteins.
2017/0281782 CARBOSILANE DENDRIMER AND AGGREGATABLE CARRIER OBTAINED USING SAID DENDRIMER FOR DRUG DELIVERY SYSTEM
The object of the present invention is to provide an aggregatable carrier material for drug delivery system and a micelle formed thereof. The present invention...
2017/0281781 INJECTABLE TISSUE ADHESIVE HYDROGEL INCLUDING GAMMA-CYCLODEXTRIN AND BIOMEDICAL USE THEREOF
Provided are an injectable tissue adhesive hydrogel including gamma-cyclodextrin (.gamma.-CD). When such an injectable tissue adhesive hydrogel including the...
2017/0281780 COLLOIDAL DISPERSION COMPRISING HPMCAS
The present disclosure relates to compositions of an aqueous colloidal dispersion of hydroxypropyl methyl cellulose acetate succinate (HPMCAS), and methods for...
2017/0281779 METHOD OF TREATING PATIENTS NON-RESPONSIVE TO PALONOSETRON
A method for treating chemotherapy-induced nausea and vomiting in individuals undergoing chemotherapy and previously treated with, and whom failed to respond...
2017/0281778 LONG-ACTING POLYMERIC DELIVERY SYSTEMS
Compositions comprised of a delivery vehicle or delivery system and an active agent dispersed within the delivery vehicle or system, wherein the delivery...
2017/0281777 LIQUID CONCENTRATED VITAMIN E COMPOSITIONS
The present patent application relates to liquid concentrated vitamin E (and/or vitamin E derivatives) compositions. The liquid composition comprises vitamin E...
2017/0281776 STEROID HORMONE COMPOSITIONS IN MEDIUM CHAIN OILS
This disclosure provides a novel pharmaceutical composition capable of forming micelles upon exposure to the gastric environment. The pharmaceutical...
2017/0281775 MODIFICATIONS OF SOLID 3-SN-PHOSPHOGLYCERIDES
Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase A.sub.2 are provided. Also disclosed are methods for making a lipid...
2017/0281774 LINACLOTIDE COMPOSITIONS
The present invention is directed to stable linaclotide compositions and methods of treating gastrointestinal disorders in patients in need thereof by...
2017/0281773 BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME
Inhibitors of BET bromodomains and compositions containing the same are disclosed. Methods of using the BET bromodomain inhibitors in the treatment of diseases...
2017/0281772 A NEURAL SUBSTRATE FOR SUGAR PREFERENCE
This invention concerns a composition and a method of modulating the craving and/or desire for natural sugar in a subject comprising: agonizing or stimulating...
2017/0281771 METHODS OF USING ADIPOSE TISSUE-DERIVED CELLS IN THE TREATMENT OF CARDIOVASCULAR CONDITIONS
Adipose derived regenerative cells are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating...
2017/0281770 SYNTHESIS OF NANOCOMPOUNDS COMPRISING ANATASE-PHASE TITANIUM OXIDE AND COMPOSITIONS CONTAINING SAME FOR THE...
This invention relates to novel nanocompounds that are cytotoxic to tumor cells when combined with ultraviolet light, the nanocompounds comprising multilayered...
2017/0281769 STABLE ANTI-IL-4Ra FORMULATION
The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL4R antibody. In...
2017/0281768 NOVEL NUCLEIC ACID MOLECULES WITH ANTITUMORAL ACTIVITY
The present invention relates to a binding molecule that specifically binds to two different epitopes of an antigen expressed on tumor cells, wherein the...
2017/0281767 COMBINATION THERAPY FOR INDUCING IMMUNE RESPONSE TO DISEASE
The present invention concerns compositions and methods of use of bispecific antibodies comprising at least one binding site for Trop-2 (EGP-1) and at least...
2017/0281766 CHIMERIC ANTIGEN AND T CELL RECEPTORS AND METHODS OF USE
The invention provides a chimeric antigen receptor (CAR) or a T cell receptor (TCR) comprising extracellular domain disclosed herein. Some aspects of the...
2017/0281765 ANTIGEN BINDING PROTEINS THAT BIND PD-L1
There is disclosed compositions and methods relating to or derived from anti-PD-L1 antibodies. More specifically, there is disclosed fully human antibodies...
2017/0281764 ANTIBODIES TO TIGIT
The invention provides monoclonal antibodies that specifically bind to TIGIT. The monoclonal antibodies have the capacity for substantial activation of T cells...
2017/0281763 Methods for treating and/or limiting development of diabetes in subjects with amyotrophic lateral sclerosis
Methods for treating and/or limiting development of diabetes in a subject with amyotrophic lateral sclerosis (ALS) by inhibiting IgG-mediated activation of...
2017/0281762 USE OF IL-17 ANTAGONISTS TO INHIBIT THE PROGRESSION OF STRUCTURAL DAMAGE IN PSORIATIC ARTHRITIS PATIENTS
The present disclosure relates to methods, uses, medicaments, pharmaceutical formulations, dosage forms, and kits for inhibiting the progression of structural...
2017/0281761 METHOD OF TREATING ALVELOR BONE LOSS THROUGH THE USE OF ANTI-SCLEROSTIN ANTIBODIES
The invention provides a method of treating alveolar bone loss involving administration of a sclerostin inhibitor to a subject in need thereof.
2017/0281760 COMBINED CANCER THERAPY WITH IMMUNE CHECKPOINT MODULATORS AND FERMENTATION PRODUCTS BY SYMBIOTIC MICROBIOTA
Combined therapy of cancer using an immune check point modulators (e.g., an immune checkpoint inhibitor) and a fermented product, which may be prepared using...
2017/0281759 BISPHOSPHONATE-CONTAINING VACCINE PHARMACEUTICAL COMPOSITION FOR HUMORAL IMMUNITY
The present invention aims to provide a vaccine pharmaceutical composition universally usable for induction of humoral immunity against various antigens and...
2017/0281758 CALICHEAMICIN ANTIBODY DRUG CONJUGATES LINKING AN AMIDOACETYL GROUP TO A SUGAR MOIETY ON CALICHEAMICIN
There is disclosed a calicheamicin antibody drug conjugate comprising a linking amidoacetyl group covalently bound to a sugar moiety on calicheamicin or...
2017/0281757 PROBIOTICS, SECRETORY IgA AND INFECTION
Ways to increase the effectiveness of probiotics are disclosed. One embodiment relates to a combination of probiotics with secretory IgA and possible uses of...
2017/0281756 COMPOSITIONS AND METHODS TO SELECTIVELY BLOCK PAIN INDUCED BY COLD
Tissue injury prompts the release of a number of proalgesic molecules that induce acute and chronic pain by sensitizing pain-sensing neurons (nociceptors) to...
2017/0281755 ORAL ADMINISTRATION OF AT LEAST ONE PHARMACEUTICAL AND/OR ANTIGENIC ACTIVE SUBSTANCE
Disclosed is a gastro-resistant vector for the oral administration of at least one pharmaceutical and/or antigenic active substance including an aqueous phase...
2017/0281754 Compositions and Methods for Enhanced Innate Immunity
The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes; a mixture of toll like...
2017/0281753 LOW, IMMUNE ENHANCING, DOSE MTOR INHIBITORS AND USES THEREOF
The present invention relates, in part, to compositions and methods for enhancement of an immune response by partial mTOR inhibition, e.g., with low, immune...
2017/0281752 Antigen Delivery System
A minimal antigen delivery system consists essentially of PEGylated stealth liposomes loaded with an immunogenic human leukocyte antigen (HLA) class restricted...
2017/0281751 EQUINE DISEASE MODEL FOR HERPESVIRUS NEUROLOGIC DISEASE AND USES THEREOF
The present invention relates to an in vivo equine disease model for equine herpesvirus-1 neurological disease comprising a horse having a low pre-exposure...
2017/0281750 Peptide Sequences and Compositions
The present specification discloses an immunogenic composition comprising polypeptide, wherein each of the polypeptides has no more than 100 amino acids, which...
2017/0281749 COMPOSITIONS COMPRISING CH505 ENVELOPES, AND TRIMERS
In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens to induce...
2017/0281748 Multi-CBV Vaccine for Preventing or Treating Type I Diabetes
The invention is directed to a vaccine comprising: i) coxsackie B virus CBV1 and CBV2, and ii) at least one coxsackie B virus selected from CBV3, CBV4, CBV5...
2017/0281747 THERAPEUTIC HPV16 VACCINES
Provided is designer nucleic acid constructs and polypeptides that can be used as therapeutic vaccines against HPV16.
2017/0281746 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELLAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM
The present disclosure relates to surface proteins of Moraxella catarrhalis and their ability to interact with epithelial cells via cell-associated fibronectin...
2017/0281745 LPS VACCINE
A vaccine composition for birds comprising as an active ingredient a structure containing O-antigen derived from Gram-negative bacteria, provided that said...
2017/0281744 METHOD OF TREATMENT
The application discloses a method of immunising against Staphylococcus aureus infection comprising a step of administering to a human patient a single dose of...
2017/0281743 Th1 vaccination priming for active immunotherapy
The present invention includes vaccine compositions and methods for using these vaccine compositions in active immunotherapy. The vaccine compositions include...
2017/0281742 H3.3 CTL Peptides and Uses Thereof
Peptides that generate an immune response to glioma-related H3.3 proteins and methods of their use are provided.
2017/0281741 PEPTIDE AND METHOD FOR REDUCING THE PHOSPHATE REQUIREMENT AND EXCRETIION FROM FARM ANIMALS
Disclosed are methods of altering metabolism of phosphate in a livestock via an antibody. The methods involve the development of an antibody against FGF-23 for...
2017/0281740 SERODIAGNOSIS OF SALMON POISONING DISEASE
Neorickettsia helminthoeca is an obligate intra-cytoplasmic bacterium that causes salmon poisoning disease (SPD), an acute, febrile, fatal disease of dogs....
2017/0281739 ALPHA-1 ANTI-TRYPSIN FOR TREATING LIVER DISEASES
Methods of treating liver diseases are provided. Accordingly there is provided a method of treating a liver disease selected from the group consisting of fatty...
2017/0281738 COMPOSITIONS AND METHODS RELATING TO ARGININOSUCCINATE SYNTHETASE
Processes and compositions for the therapeutic treatment of pathogenic Gram-negative bacterial infection are provided whereby argininosuccinate synthetase or...
2017/0281737 UNIVERSAL PLATFORM FOR TARGETING THERAPIES TO TREAT NEUROLOGICAL DISEASES
The present invention provides a universal delivery platform of functional, heterologous compounds to specific cells using toxins modified to include a...
2017/0281736 CHOLIX TOXIN-DERIVED FUSION MOELCULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO
The present disclosure relates to pharmaceutical compositions comprising a non-naturally occurring fusion molecule and one or more pharmaceutically acceptable...
2017/0281735 Compositions and Methods for the Treatment of Photoaging and Other Conditions
Compositions and methods for the treatment of skin disorders or disease are provided.
2017/0281734 FACTOR VIII POLYPEPTIDE FORMULATIONS
The present invention provides a formulation of a Factor VIII polypeptide, e.g., FVIII-Fc, and methods of using the same. The FVIII polypeptide can be a...
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