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Patent # Description
2017/0281631 PHARMACEUTICAL FORMULATION OF PALBOCICLIB AND A PREPARATION METHOD THEREOF
The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation...
2017/0281630 METHOD OF TREATMENT AND COMPOSITIONS COMPRISING A DUAL PI3K DELTA-GAMMA KINASE INHIBITOR AND A CORTICOSTEROID
This present disclosure relates to a method of treating autoimmune, respiratory and/or inflammatory diseases or conditions, e.g., asthma, COPD, rheumatoid...
2017/0281629 DOSING REGIMEN FOR MISSED DOSES FOR LONG-ACTING INJECTABLE PALIPERIDONE ESTERS
The present application provides a method for treating patients in need of psychiatric treatment, wherein said patient is being treated with the 3-month...
2017/0281628 MOLECULAR TARGETS FOR THE TREATMENT OF WOUNDS, IN PARTICULAR CHRONIC WOUNDS
The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting...
2017/0281627 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS
The present disclosure relates generally to toll like receptor modulator compounds, such as diamino pyrido[3,2 D] pyrimidine compounds and pharmaceutical...
2017/0281626 PYRIMIDINEDIONE COMPOUNDS
Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy...
2017/0281625 METHODS OF TREATING HEART FAILURE
Methods of treating heart failure include administering to a subject having heart failure an effective amount of a triazole compound that is an agonist of the...
2017/0281624 COMBINATION THERAPIES OF ALK INHIBITORS
A method of treating a cancer in a subject is disclosed, comprising administering to the subject an immunomodulator and a second therapeutic agent, wherein:...
2017/0281623 SOLID FORMS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR
The present invention provides a solid form and composites thereof, which are useful as an inhibitor of EGFR kinases and which exhibit desirable ...
2017/0281622 DERIVATIVES OF MACROCYCLIC N-ARYL-2-AMINO-4-ARYL-PYRIMIDINE POLYETHERS AS INHIBITORS OF FTL3 AND JAK
The present invention relates to a compound with the following formula: formula (I) or a salt and/or a pharmaceutically acceptable solvate thereof, in...
2017/0281621 SUBSTITUTED PYRIDAZINES AS SKELETAL MUSCLE MODULATORS
Provided are compounds of Formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6,...
2017/0281620 CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY
A very stable, selective and renally safe sodium channel blocker represented by the formula: ##STR00001## The invention also includes a variety of compositions,...
2017/0281619 COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH A SELECTIVE BCL-2 INHIBITOR
The present invention is directed to a combination therapy involving a type II anti-CD20 antibody and a selective BCL-2 inhibitor for the treatment of a...
2017/0281618 INJECTABLE FLOWABLE COMPOSITION COMPRISING BUPRENORPHINE
The present invention is directed to a buprenorphine sustained release delivery system capable of delivering buprenorphine, a metabolite, or a prodrug thereof...
2017/0281617 COMPOSITIONS AND METHODS FOR INCREASING THE METABOLIC LIFETIME OF DEXTROMETHORPHAN AND RELATED PHARMACODYNAMIC...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
2017/0281616 MORPHINAN COMPOUNDS
This invention relates to novel morphinan compounds and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a...
2017/0281615 EXTENDED RELEASE, ABUSE DETERRENT DOSAGE FORMS
Extended release, abuse deterrent dosage forms comprising crush-resistant controlled-release particles that provide abuse deterrent properties to the dosage...
2017/0281614 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
Chemical entities that modulate PI3 kinase activity, pharmaceutical compositions containing the chemical entities, and methods of using these chemical entities...
2017/0281613 Combination Therapy
Described herein are compounds and compositions for treating glaucoma and/or reducing introcular pressure. Compositions may comprise an isoquinoline compound...
2017/0281612 Methods for the Treatment of Cystic Fibrosis
The present invention is directed to a method of treating or lessening the severity of cystic fibrosis in a patient, comprising the step of administering to...
2017/0281611 QUINOLINES AND THEIR USE FOR TREATING ENDOPLASMIC RETICULUM STRESS-CAUSED DISEASES
Provided herein are quinolines, e.g., a compound of Formula (I) or (IB), pharmaceutical compositions thereof, and methods of their use for treating,...
2017/0281610 TOPICAL RETINOID COMPOSITIONS
The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active...
2017/0281609 Granulate Formulation of 5-methyl-1-phenyl-2-(1H)-pyridone and Method of Making the Same
The disclosure relates to granulate formulations of pirfenidone and methods of making such formulations.
2017/0281608 Use of 4-Aminopyridine to Improve Neuro-Cognitive and/or Neuro-Psychiatric Impairment in Patients with...
Disclosed herein are methods and compositions related to use of aminopyridines, such as 4-aminopyridine, to improve the neuro-cognitive impairments and related...
2017/0281607 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF DIABETES
This invention relates to compositions and methods for treating type I diabetes. Compositions of the invention include active compounds such as harmine, INDY,...
2017/0281606 METHODS OF TREATING HEPATIC ENCEPHALOPATHY
The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific...
2017/0281605 COMPOSITIONS AND METHODS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS IN RESPONDERS
A method for treating amyotrophic lateral sclerosis (ALS) in a subject in need thereof comprising administering to said subject an effective amount of...
2017/0281604 COMPOSITIONS AND METHODS FOR TREATING PLASMA CELL DISORDERS AND B-CELL PROLYMPHOCYTIC DISORDERS
Disclosed herein are methods of treating conditions, which may be associated with elevated levels of plasma cells and/or B-cells, with a therapeutically...
2017/0281603 THIAZOLIDE COMPOUNDS FOR TREATING VIRAL INFECTIONS
Thiazolide compounds, such as nitazoxanide and/or tizoxanide, may be used against viruses belonging to the Picornaviridae family or the Paramyxoviridae family.
2017/0281602 SOLID FORMS OF (S)-2-METHOXY-3--PROPIONIC ACID AND OF SALTS THEREOF
The present invention relates to solid forms of (S)-2-methoxy-3-{442-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxyl-benzo[b]thio- phen-7-yl}-propionic acid, and of...
2017/0281601 NOVEL COMPOUNDS AND COMPOSITIONS AND METHODS OF USE
Described herein are compounds useful in the modulation of blood uric acid levels, formulations containing them and methods of using them. In some embodiments,...
2017/0281600 INTRAVENOUS FORMULATION AND LC/MS/MS ANALYSIS METHOD FOR GMC1
Certain embodiments are directed to a GMC1 co-solvent formulation. The GMC1 co-solvent formulation described herein can be used for the treatment of prostate...
2017/0281598 METHODS AND COMPOSITIONS FOR TREATING CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE
The present invention provides methods for treating and preventing the reoccurrence of C. diff infection by administering an immunoglobulin concentrate in...
2017/0281597 METHODS OF USING (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOI- ...
Stereomerically pure (+)-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoiso- indoline-1,3-dione, substantially free of its (-) isomer, and...
2017/0281596 PHARMACEUTICAL COMBINATION CONTAINING AN ANALGESIC AGENT AND AN ANTISPASMODIC AGENT
"PHARMACEUTICAL COMBINATION CONTAINING AN ANALGESIC AGENT AND AN ANTISPASMODIC AGENT", whose analgesic agent is the Ketorolac Tromethamine, which is physically...
2017/0281595 FORMULATION AND METHOD TO INDUCE A DEEP STATE OF RELAXATION
A relaxation formulation structured to induce a deep state of relaxation in a person comprises amounts of tryptophan, melatonin, vitamin B3, and vitamin B6....
2017/0281594 METHODS FOR TREATING FIBROPROLIFERATIVE DISORDERS IN A MAMMAL
A topical drug composition for treating a .beta.-catenin-mediated disorder in a mammal is provided comprising a Nefopam compound selected from Nefopam, or a...
2017/0281593 Methods of Treating Fatty Liver Disease
The disclosure provides methods for treating fatty liver disease and associated conditions by inhibiting the synthesis of glucosphingolipids, as exemplified by...
2017/0281592 METHOD OF TREATING NEURODEGENERATIVE DISORDERS
The present disclosure is directed, at least in part, to disease-modifying treatments for neurodegenerative disorders. In one embodiment, a method of delaying...
2017/0281591 PRODRUG OF GREEN TEA EPIGALLOCATECHIN-3-GALLATE (PRO-EGCG) FOR USE IN THE TREATMENT OF ENDOMETRIOSIS
Method of treating endometriosis and related indications, comprising the administration of Pro-EGCG, a synthetic and derivative product of ...
2017/0281590 Methods of Reducing Blood Lactate Concentration
The present invention is directed to methods for reducing blood lactate concentration during exercise, physical activity or athletic performance.
2017/0281589 USE OF STING AGONISTS TO TREAT CHRONIC HEPATITIS B VIRUS INFECTION
Provided herein are methods of treating a subject having hepatitis B viral (HBV) infection. More specifically, disclosed herein are methods of stimulating the...
2017/0281588 Compositions and Methods for Treating Epithelial Cancer
The present invention provides the eutomeric isomer of the compound of formula (I), or a salt or solvate thereof, which can be used to treat epithelial cancer...
2017/0281587 ERYTHROCYTE FUNCTION IMPROVING AGENT
An object of the present invention is to provide an agent for improving red blood cell function which has both high antioxidant action and high ability to...
2017/0281586 SOLID MOLECULAR DISPERSION OF FESOTERODINE HYDROGEN FUMARATE AND POLYMERIC BINDER
The present invention relates to solid molecular dispersion of fesoterodine hydrogen fumarate and a polymeric binder. The invention also relates to an inert...
2017/0281585 METHODS FOR THE TREATMENT OF SIALORRHEA
The present invention provides safe and effective methods for the treatment of sialorrhea (excessive drooling) by administering an effective amount of...
2017/0281584 Misoprostol Dispersible Tablet
The present invention relates to a solid pharmaceutical formulation comprising misoprostol or a pharmaceutically acceptable salt thereof. In particular, the...
2017/0281583 METHODS FOR TREATING BRAIN INJURY
The treatment options for treating blast-induced and noise-induced traumatic brain injury and tinnitus are limited. Thus, the current invention provides...
2017/0281582 ENHANCER FOR EATING ACTIVITY AND/OR GASTROINTESTINAL ACTIVITY
An agent for secreting ghrelin, comprising ornithine or a salt thereof as an active ingredient, an agent for enhancing eating activity, comprising ornithine or...
2017/0281581 SPORTS HEALTH PERFORMANCE COMPOSITION BACKGROUND
A topical composition that includes L-arginine that is used as a sports health composition. The composition can further include forskolin. Disclosed is a...
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