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Patent # Description
2017/0290843 METHOD OF ADJUVANT TREATMENT WITH CHLOROPHYLLIN CONTAINING THERAPEUTIC PREPARATION INCLUDING FOR...
A method of increasing abundance of hematopoietic stem cells and progenitor cells and an adjuvant method of radiotherapy based treatment for radioprotection of...
2017/0290842 RNA POLYMERASE I INHIBITORS AND USES THEREOF
Provided are novel compounds which are capable of inhibiting an activity of RNA polymerase I, and uses thereof in treating diseases or disorders modulated by...
2017/0290841 AQUEOUS COMPOSITION
An aqueous composition having an excellent antiseptic effect is provided. An aqueous composition comprising a compound represented by Formula (1), wherein X...
2017/0290840 CORNEAL THICKNESS ADJUSTMENT AGENT
The present invention provides a novel corneal thickness modulating agent. The present invention pertains to a corneal thickness modulating agent containing ...
2017/0290839 BICYCLIC HETEROCYCLES AS FGFR4 INHIBITORS
The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR3 and/or FGFR4 enzyme and...
2017/0290838 QUINAZOLINES AND AZAQUINAZOLINES AS DUAL INHIBITORS OF RAS/RAF/MEK/ERK AND PI3K/AKT/PTEN/MTOR PATHWAYS
The present application provides novel quinazolines and azaquinazolines and pharmaceutically acceptable salts thereof. Also provided are methods for preparing...
2017/0290837 SUBSTITUTED BENZENE COMPOUNDS
The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds...
2017/0290836 ARYLQUINAZOLINES
The invention relates to novel compounds of the formula (I) which can be used for the inhibition of serine-threonine protein kinases and for the sensitisation...
2017/0290835 COMPOSITIONS AND METHODS FOR INCREASING NEUROTROPHIC PEPTIDES
A pharmaceutical composition is provided which includes a pharmaceutically acceptable excipient and a pharmaceutically and physically acceptable amount of a...
2017/0290834 Naphthyridinone derivatives and their use in the treatment, amelioration or prevention of a viral disease
The present invention relates to a compound having the general formula (V), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph,...
2017/0290833 SOLID STATE FORMS OF A QUINAZOLINE DERIVATIVE AND ITS USE AS A BRAF INHIBITOR
This application relates to various salts and solid state forms of Compound (I). This application also relates to pharmaceutical compositions and therapeutic...
2017/0290832 IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER
The present invention is directed to imidazolin-5-one derivatives, pharmaceutical compositions containing them, and their use as FASN inhibitors, in for...
2017/0290831 MODIFIED MICROBUBBLE
A modified microbubble is provided. The modified microbubble includes an albumin microbubble and a plurality of chitosan oligosaccharide lactates. The albumin...
2017/0290830 SMALL MOLECULE REGULATORS OF STEROID RECEPTOR COACTIVATORS AND METHODS OF USE THEREOF
Small molecule regulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing...
2017/0290829 USE OF PIMOBENDAN FOR THE REDUCTION OF HEART SIZE AND/OR THE DELAY OF ONSET OF CLINICAL SYMPTOMS IN PATIENTS...
The invention relates to pimobendan for use in a method of reducing the heart size and/or delaying the onset of clinical symptoms in a patient suffering from...
2017/0290828 1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; ##STR00001## a method for manufacturing the compounds of...
2017/0290827 INHIBITORS OF HEPATITIS C VIRUS
Compounds of Formula I are disclosed ##STR00001## As well as pharmaceutically acceptable salts thereof. Methods of using said compounds and pharmaceutical...
2017/0290826 CANCER TREATMENT METHOD
Invented is a method of treating cancer or a pre-cancerous syndrome in a mammal, including a human, in need thereof which comprises the administration of an...
2017/0290825 PYRUVATE KINASE ACTIVATORS FOR USE IN THERAPY
Described herein are methods for using compounds that activate pyruvate kinase.
2017/0290824 2-AMINOTHIAZOLE DERIVATIVE OR SALT THEREOF
A compound which is useful as an active ingredient for a pharmaceutical composition for treating urine storage dysfunction, voiding dysfunction, lower urinary...
2017/0290823 METHOD OF TREATING PARKINSON'S DISEASE WITH A DIARYLMETHYLPIPERAZINE COMPOUNDS EXHIBITING DELTA OPIOID RECEPTOR...
Compositions and methods for treatment of Parkinson's disease to reduce the negative side effects of the disease by administering a therapeutically effective...
2017/0290822 USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNF THERAPY
This application provides for a method of treating a human patient afflicted with anti-TNF.alpha. refractory Crohn's disease, of treating a human patient...
2017/0290821 ANTI-INFLUENZA VIRUS AGENT AND SCREENING METHOD FOR ANTI-INFLUENZA VIRUS AGENT
The present invention provides an anti-influenza virus agent that targets biomolecules of host cells including human cells and a method of screening a...
2017/0290819 SMALL MOLECULE THERAPIES FOR PULMONARY HYPERTENSION
The present disclosure relates to pirfenidone (5-methyl-1-phenyl-2-(1H)-pyridone) and its derivatives and pharmaceutically acceptable salts thereof, use of...
2017/0290818 NOVEL COMPOUNDS ALPHA v BETA 6 INTEGRIN ANTAGONISTS
A compound according to formula (I) ##STR00001## wherein R.sub.1 is hydrogen, cyclopropyl, or pyrazolyl, wherein said pyrazolyl is optionally substituted by one...
2017/0290817 NOVEL COMPOUNDS ALPHA v BETA 6 INTEGRIN ANTAGONISTS
A compound of formula (I): ##STR00001## which is 4-(3-fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl- ...
2017/0290816 BENZOMORPHAN ANALOGS AND THE USE THEREOF
In one aspect, the invention provides compounds of Formula (I) or (II): (I) or (II) and pharmaceutically acceptable salts and solvates thereof, wherein...
2017/0290815 GLUTAMINASE INHIBITORS
A compound, or a pharmaceutically acceptable salt thereof, having a structure of: ##STR00001## wherein A is a ring; Y.sup.1 and Y.sup.2 are each independently...
2017/0290814 METHODS OF TREATMENT OF CHOLESTASIS AND FIBROSIS
The present invention relates compounds useful and their use for treating cholestatic and fibrotic diseases.
2017/0290813 METHODS OF TREATMENT FOR CHOLESTATIC AND FIBROTIC DISEASES
The present invention relates to a synergistic combination of active ingredients for use in the treatment of fibrotic diseases.
2017/0290812 METHODS OF TREATMENT FOR CHOLESTATIC AND FIBROTIC DISEASES
The present invention relates to the compound [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) or...
2017/0290811 ORAL FORMULATIONS OF DEFERASIROX
Orally administerable deferasirox formulations are disclosed having reduced release under gastric conditions and fast release at near neutral pH or at neutral pH.
2017/0290810 ANTI-FUNGAL COMPOSITIONS FOR TREATING NAILS AND METHODS FOR FABRICATING AND USING THEREOF
Pharmaceutical compositions for treating, mitigating or preventing fungal nail diseases, disorders or pathologies are described, the compositions comprising at...
2017/0290809 ANTIVIRAL AGENTS AND USES THEREOF
The present invention relates to compounds which are found to exhibit an antiviral effect. The compounds are modulators of the activity of the viral...
2017/0290808 REDUCING TUMOR BURDEN BY ADMINISTERING CCR1 ANTAGONISTS IN COMBINATION WITH PD-1 INHIBITORS OR PD-L1 INHIBITORS
The present invention provides methods for reducing tumor burden, tumor growth, tumor progression, and/or metastasis in a subject suffering from a solid tumor...
2017/0290807 PHARMACEUTICAL FILM COMPOSITION
The present invention relates to Film Compositions of Ondansetron or its pharmaceutically acceptable salt thereof, which dosage forms are useful for the...
2017/0290806 PCSK9 Inhibitors and Methods of Use Thereof
The present invention relates to compositions and methods for treating lipid disorders in a subject. In one embodiment, the compositions of the present...
2017/0290805 EXTENDED RELEASE PHARMACEUTICAL FORMULATIONS WITH CONTROLLED IMPURITY LEVELS
The present invention provides extended release pharmaceutical formulations of valsartan with controlled impurity levels. Particularly, the present invention...
2017/0290804 TREATMENT OF ATOPIC DERMATITIS WITH INDIGO NATURALIS OR INDIGO PRODUCING PLANT EXTRACT
A pharmaceutical or cosmetic composition comprising an Indigo Naturalis or Indigo-producing plant extract for treating atopic dermatitis and any form of...
2017/0290803 PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF
The invention relates to oral, topical or injectable compositions for combating liver fluke parasites in mammals, comprising at least one indole derivative...
2017/0290802 Novel Small Fibre Neuropathy Treatment
The present invention is directed to the treatment of small fibre neuropathy comprising administering to a subject in need thereof, a therapeutically effective...
2017/0290801 Pet Food Compositions Including a Sustained-Release Lipoic Acid and Methods of Manufacture and Use Thereof
The invention encompasses pet food composition that delivers a slow, sustained-release amount of lipoic acid or a salt thereof when fed orally to a companion...
2017/0290800 GPR40 AGONISTS IN ANTI-DIABETIC DRUG COMBINATIONS
Disclosed are compositions comprising (a) a GPR40 agonist and (b) an SGLT2 inhibitor, and methods for treating of disorders that are affected by the modulation...
2017/0290799 PHARMACEUTICAL COMPOSITION FOR USE IN INCREASING THE TROPHISM OF NASAL MUCOSA
Composition for topical application, for use in increasing the trophism of nasal mucosa, comprising an ester of vitamin E with a carboxylic acid of formula...
2017/0290798 Methods of Reducing Blood Lactate Concentration
The present invention is directed to methods for reducing blood lactate concentration during exercise, physical activity or athletic performance.
2017/0290797 COMBINATION THERAPIES FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS
The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising...
2017/0290796 COMBINATION THERAPY WITH AN ANTI-HYALURONAN AGENT AND THERAPEUTIC AGENT
Provided herein is combination cancer therapy effected by administering a polymer-conjugated hyaluronidase, and a tumor-targeted taxane, and optionally a...
2017/0290795 URAT1 INHIBITOR
Provided are a compound represented by the following Formula (III), a tautomer or stereoisomer of the compound, or a pharmaceutically acceptable salt or...
2017/0290794 Method for Treating Eczema
A method for treating eczema including the steps of applying an isothiocyanate functional surfactant to an area affected by eczema, wherein the isothiocyanate...
2017/0290793 FORMULATIONS FOR TREATING PAIN
Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The...
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