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Patent # Description
2017/0298028 Process for Producing Fluorocytosine and Fluorocytosine Derivatives
The present invention relates to a method of manufacturing a fluorocytosine-based compound of Formula I. ##STR00001## The invention also relates to a compound...
2017/0298027 PYRIMIDINES AS SODIUM CHANNEL BLOCKERS
The present disclosure provides substituted pyrimidine compounds of Formula (I), and the pharmaceutically acceptable salts, prodrugs, and solvates thereof,...
2017/0298026 ALL PURPOSE RAFT AGENT
The present invention relates to a RAFT agent of formula (I) where R.sub.1, R.sub.2 and R.sub.3 are each independently selected from H and optionally...
2017/0298025 HISTONE DEMETHYLASE INHIBITORS
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine...
2017/0298024 CYCLOHEXYL PYRIDINE DERIVATIVE
A problem of the present invention is to provide a new compound which has NK.sub.1 receptor antagonist activity, whose CYP3A4 inhibitory activity is reduced...
2017/0298023 4-(METHYLAMINOPHENOXY)PYRDIN-3-YL-BENZAMIDE DERIVATIVES FOR TREATING CANCER
The present invention provides a novel compound having an excellent antitumor effect, stability and metabolic stability. The compound of the present invention...
2017/0298022 Diamino-Pyridine, Pyrimidine, and Pyridazine Modulators of the Histamine H4 Receptor
Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H.sub.4 receptor modulators, and in pharmaceutical compositions and methods for the...
2017/0298021 2-Aminopyridine-based Selective Neuronal Nitric Oxide Synthase Inhibitors
Aminopyridine compounds, as can be used in conjunction with methods for modulation of nitric oxide synthase activity.
2017/0298020 METHODS AND COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS AND VIRAL INFECTIONS
The invention generally relates to methods and compounds for treating proliferative disorders, viral infections, or both. In some embodiments, the invention...
2017/0298019 PROLYL HYDROXYLASE INHIBITORS
Disclosed herein are prolyl hydroxylase inhibitors that can stabilize hypoxia inducible factor-1 alpha (HIF-1.alpha.), as well as hypoxia inducible factor-2...
2017/0298018 STABLE APREMILAST CRYSTALLINE FORM II FREE OF SOLVATE AND METHOD OF MAKING THE SAME
A stable Crystalline Form II of non-solvate of Apremilast (Formula I), methods of making Form II, pharmaceutical compositions comprising Form II, and their...
2017/0298017 Mono- or di-substituted indole derivatives as dengue viral replication inhibitors
The present invention concerns mono- or di-substituted indole derivatives (I) which are useful to prevent or treat dengue viral infections and also relates to...
2017/0298016 PYRROLIC AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF
The present invention discloses a pyrrolic amide compound shown as a formula I, or crystal forms thereof, and pharmaceutically acceptable salts, hydrates or...
2017/0298015 PHOTOCHEMICAL REACTION DEVICE, PHOTOCHEMICAL REACTION METHOD USING SAME, AND LACTAM PRODUCTION METHOD USING...
Provided is a photochemical reaction device wherein two partitions formed from an optically transparent material are arranged apart from each other between a...
2017/0298014 SULFIDE ALKYL COMPOUNDS FOR HBV TREATMENT
The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to...
2017/0298013 2,2' -DIAMINO BIARYLS WITH TWO SECONDARY AMINES AND PRODUCTION THEREOF BY ELECTROCHEMICAL COUPLING
Novel 2,2'-diamino biaryls of formula (I), (II) and (III), wherein R1-R10, R1'-R10', X1-X3 and X1-X3' are defined in claim 1. The invention also relates to an...
2017/0298012 STEREOSELECTIVE PROCESS TO OBTAIN (Z)-5-CYCLYLOXY-2-[(E)-METHOXYIMINO]-3-METHYL-PENT-3-ENIC ACID METHYL ...
The present invention relates to a process for preparation of intermediates (Z,2E)-5-hydroxy-2-methoxyimino-N-methyl-pent-3-enamides from 4-substituted...
2017/0298011 ALPHA-AMINOAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
The present disclosure relates to an .alpha.-aminoamide derivative compound and a pharmaceutical composition containing the same. According to various...
2017/0298010 MULTIVALENT COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF BRAIN DAMAGE
The present invention relates to compounds of general formula (I) ##STR00001## and pharmaceutically acceptable salts thereof; wherein R1-R11, L, Z, Y, and Z are as...
2017/0298009 METHOD FOR THE MANUFACTURE OF N,N-DIALLKYLLACTAMIDE
A method for the manufacture of N,N-dialkyllactamide, whereby at least one of the compounds selected from the series made of alkyl lactate, lactide and...
2017/0298008 TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION
The present invention provides a process of producing a trifluoromethoxylated aryl or trifluoromethoxylated heteroaryl having the structure: ##STR00001## ...
2017/0298007 Preparation Of Thermoplastic Epoxidized Polymers And Thermosetting Materials From Triglycerides
A method i for forming an epoxidized polymer is provided. The method may include mixing an epoxidized plant oil with a synthetic epoxy resin and crosslinking...
2017/0298006 SUBSTITUTED 1,2-DIHYDROQUINOLINES WITH LOW CONTAMINANT LEVELS AND PROCESSES FOR PREPARING
Processes for preparing compositions comprising substituted 1,2-dihydroquinolines and having low or undetectable levels of substituted anilines, wherein the...
2017/0298005 CURABLE COMPOSITION FOR INKJET, AND METHOD FOR MANUFACTURING ELECTRONIC COMPONENT
Provided is a curable composition for inkjet which can have a prolonged pot life even under an environment in an inkjet device that is warmed to 50.degree. C....
2017/0298004 BACTERIAL TOPOISOMERASE INHIBITORS AND USE THEREOF
The present invention provides novel compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides...
2017/0298003 COUPLING OF DISTILLATIVE PURIFICATION WITH A PARTIAL CONDENSER FOR PRE-PURIFICATION OF ISOPHORONEDIAMINE
A process for fine purification of isophoronediamine (IPDA), including producing IPDA by aminating hydrogenation of isophorone nitrile in the presence of at...
2017/0298002 METHOD OF PRODUCING N-ALKYL POLYAMINES
In one embodiment, the invention presents a process for the preparation of N-alkyl polyamines that includes (i) the conversion of an amino alcohol to an...
2017/0298001 TREPROSTINIL DERIVATIVES AND COMPOSITIONS AND USES THEREOF
The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any...
2017/0298000 REDUCED FOULING PROCESS FOR THE PRODUCTION OF METHYL METHACRYLATE
Fouling of an MMA process is reduced by strategically removing an aqueous slip stream.
2017/0297999 METHOD FOR PRODUCING TRIPHENYLBUTENE DERIVATIVE
We provide a novel and useful process for preparing triphenyl-butene derivative. A process for the preparation of a compound represented by Formula (IV): ...
2017/0297998 METHOD FOR PRODUCING DIESTERS OF TEREPHTHALIC ACID WITH ENRICHMENT OF RECIRCULATED ALCOHOL
The present invention relates to a process for preparing a terephthalic diester by reacting terephthalic acid with at least one alcohol, wherein terephthalic...
2017/0297997 METHOD FOR PRODUCING DIESTERS OF TEREPHTHALIC ACID WITH A DEHYDRATION OF RECIRCULATED ALCOHOL
The present invention relates to a process for preparing a terephthalic diester by reacting terephthalic acid with at least one alcohol, wherein terephthalic...
2017/0297996 METHOD FOR PRODUCING DIESTERS OF TEREPHTHALIC ACID WITH CIRCULATION OF THE REACTION MIXTURE
The present invention relates to a process for preparing a terephthalic diester by reacting terephthalic acid with at least one alcohol, wherein terephthalic...
2017/0297995 METHODS OF SYNTHESIZING A PROSTACYCLIN ANALOG
The present invention provides processes for preparing a prostacyclin analogue of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R.sup.10...
2017/0297994 METHOD AND APPARATUS FOR MANUFACTURING CONTINUOUS ACRYLIC ACID THROUGH PROPANE PARTIAL OXIDATION REACTION
This invention relates to a method of continuously preparing acrylic acid and an apparatus using the same, the method including: (1) subjecting a feed...
2017/0297993 ORGANIC COMPOUNDS
A compound represented by the formula I ##STR00001## R.sub.1 is --(CHR.sub.4).sub.m--(CHR.sub.5).sub.n--(CHR.sub.6).sub.o--CHO, with R.sub.4, R.sub.5,...
2017/0297992 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS
A fragrance precursor of 3-(4-isobutyl-2-methyl phenyl)propanal, comprising at least an enamine and/or an aminal as reaction product of ...
2017/0297991 METHODS FOR SELECTIVE OXIDATION OF ALPHA TOCOTRIENOL IN THE PRESENCE OF NON-ALPHA TOCOTRIENOLS
A method of producing alpha-tocotrienol quinone or a stereoisomer thereof, the method comprising selective opening of alpha-tocotrienol chroman to...
2017/0297990 PROCESS FOR PRODUCING ALCOHOL ANALOGUE
Provided is a process for producing an optically active hydroxyaldehyde or aminohydroxyaldehyde. The process for producing an optically active hydroxyaldehyde...
2017/0297989 PROCESS FOR PRODUCING A MULTIFUNCTIONAL PRODUCT AND THE DEVICE FOR APPLYING SAID PROCESS
A process by which the raw material, a gas comprising mainly hydrogen, carbon monoxide and carbon dioxide, is introduced into a first reactor together with a...
2017/0297988 Efficient Catalytic Greenhouse Gas-Free Hydrogen and Aldehyde Formation from Alcohols
Catalytic preparation of hydrogen and aldehyde(s) from alcohols, including bioalcohols, without production of carbon monoxide or carbon dioxide.
2017/0297987 METHOD OF PRODUCING ALIPHATIC ALDEHYDE COMPOUND HAVING TERMINAL CONJUGATED DIENE STRUCTURE AND INTERMEDIATE...
Provided are a method for producing a terminal conjugated dienal compound without an oxidation reaction and a terminal hydroxyacetal compound useful as an...
2017/0297986 SYSTEMS AND METHODS FOR PRODUCING DIMETHYL ETHER FROM NATURAL GAS
Integrated methods and systems are disclosed for the production of dimethyl ether. The method may include reforming natural gas to syngas in a first reactor;...
2017/0297985 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL
The present methods treat neurofibromatosis by administering to a subject perillyl alcohol or iso-perillyl alcohol The present methods also treat ...
2017/0297984 ETHYNYLATION OF POLYUNSATURATED ALDEHYDES AND KETONES
The present invention relates to a catalytic process for the ethynylation of specific poly-unsaturated aldehydes and ketones.
2017/0297983 METHODS OF FORMING DIOL COMPOUNDS
Methods of forming a C.sub.4 to C.sub.7 diol compound, the methods including a first step of reacting a C.sub.4 to C.sub.7 dicarboxylic acid with hydrogen...
2017/0297982 AZEOTROPIC COMPOSITIONS OF HYDROGEN FLUORIDE AND Z-3,3,3-TRIFLUORO-1-CHLOROPROPENE
An azeotropic or quasi-azeotropic composition including hydrogen fluoride, Z-3,3,3-trifluoro-1-chloropropene and one or more (hydro)halocarbon compounds...
2017/0297981 PROCESS FOR THE PREPARATION OF HALO-SUBSTITUTED BENZENES
The invention relates to a process for the preparation of compound of formula (I) wherein R.sub.1 is halogen and R.sub.2 is halogen or hydrogen; comprising a)...
2017/0297979 EMBEDDED ALKANE DEHYDROGENATION SYSTEMS AND PROCESSES
Systems for dehydrogenating an alkane are provided. An exemplary system includes a furnace and further includes alkane heating chambers, regeneration mixture...
2017/0297978 FLUIDIZABLE ALKANE DEHYDROGENATION CATALYST
Fluidizable catalysts for oxygen-free oxidative dehydrogenation of alkanes to corresponding olefins. The catalysts contain 10-20% (by weight per total catalyst...
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