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Patent # Description
2017/0306407 MIRNAS AS NON-INVASIVE BIOMARKERS FOR INFLAMMATORY BOWEL DISEASE
The present invention relates to a method for diagnosis of Inflammatory Bowel Disease (IBD) based on the determination of expression profiles of miRNAs...
2017/0306406 DNA METHYLATION MARKERS FOR NEURODEVELOPMENTAL SYNDROMES
The present disclosure provides epigenetic signatures, comprising genomic CpG dinucleotide sequences, genes, and/or genomic regions, which are differentially...
2017/0306405 DNA METHYLATION STATUS AS A BIOMARKER OF ALCOHOL USE AND ABSTINENCE
This disclosure provides methods and materials for determining whether or not an individual is using alcohol, and also for determining whether or not the...
2017/0306404 HIGH THROUGHPUT SEQUENCING
The invention relates to a high throughput method for determining telomere length of mammalian chromosomal DNA; primers for use in said method; a kit...
2017/0306403 Molecular Diagnosis of FSHD By Epigenetic Signature
The present invention includes methods of determining whether an individual in need thereof has, or is at risk of developing, facioscapulohumeral muscular...
2017/0306402 SYSTEMS AND METHODS FOR CHARACTERIZATION OF MULTIPLE SCLEROSIS
Methods and systems to characterize multiple sclerosis (MS) in a subject, e.g., in a subject having a progressive form of MS are disclosed.
2017/0306401 METHODS FOR IDENTIFICATION AND PREDICTION OF MULTIPLE SCLEROSIS DISEASE AND THERAPY RESPONSE
Methods and compositions for diagnosing multiple sclerosis ("MS") in an individual or the predisposition or risk of MS, and for the prediction of the response...
2017/0306400 BIOMARKER FOR DIAGNOSIS OF AGING OR AMYOTROPHIA
Provided is a novel biomarker for the diagnosis of aging or amyotrophy. Provided are a method for determining the state of aging or amyotrophy, a method for...
2017/0306399 METHODS FOR CHARACTERIZING ALTERNATIVELY OR ABERRANTLY SPLICED MRNA ISOFORMS
The disclosure provides method and kits for characterizing spliced m RNA isoforms. The disclosure also provides methods of screening for mutations and...
2017/0306398 MUTANT PORES
The invention relates to mutant forms of Msp. The invention also relates to polynucleotide characterisation using Msp.
2017/0306397 alpha-Hemolysin Variants and Uses Thereof
Described herein are variants of alpha-hemolysin having at least one mutation, such as a mutation to a positive charge. In certain examples, the mutation is...
2017/0306396 ELECTRODES FOR BIOMOLECULAR SEQUENCING DEVICE, AND BIOMOLECULAR SEQUENCING DEVICE, METHOD, AND PROGRAM
The nano-gap electrode pair 12 is disposed so that a biomolecule joined to at least one or more types of a single molecule included in a sample passes an...
2017/0306395 MULTIPLEX METHYLATION-SPECIFIC AMPLIFICATION SYSTEMS AND METHODS
The present invention relates to systems and methods for performing multiplex amplification reactions. In particular, the present invention relates to...
2017/0306394 DEVICES AND METHODS FOR CONTROLLING REVERSIBLE CHEMICAL REACTIONS AT SOLID-LIQUID INTERFACES BY RAPID...
Devices and methods for controlling reversible chemical reactions at solid-liquid interfaces are disclosed. In particular, the invention relates to a method of...
2017/0306393 Method for Detecting Target Nucleic Acid
The disclosure of this Description includes: a step of preparing a solid-phase body provided with a detection probe having a predetermined nucleotide sequence;...
2017/0306392 RANDOM NUCLEOTIDE MUTATION FOR NUCLEOTIDE TEMPLATE COUNTING AND ASSEMBLY
A method for determining the number of nucleic acid molecules (NAMs) in a group of NAMs, comprising i) obtaining an amplified and mutagenized group of NAMs...
2017/0306391 METHODS AND TOOLS FOR ANALYZING HYBRIDIZATION
Provided herein are methods for determining the presence of a mutant of target polynucleotides in a sample solution by contacting the sample solution and a...
2017/0306390 Method and System for DNA Mixture Analysis
The present invention pertains to a process for automatically analyzing mixed DNA samples. Specifically, the process comprises the steps of obtaining a mixed...
2017/0306389 NOVEL MEASURING METHOD AND COMPOSITION USING KINASE
The present invention provides a measuring method for at least one of a kinase forward reaction substrate, a phosphorylated product thereof, and a precursor...
2017/0306388 Method for the Identification of Inhibitors and Activators of Thymidylate Kinases
Provided herein is a method of producing large amounts of the enzyme thymidylate kinase from multiple species for drug discovery purposes. Also provided herein...
2017/0306387 COMPOSITIONS AND METHODS FOR IDENTIFYING ENZYME AND TRANSPORT PROTEIN INHIBITORS
The invention is directed to compositions, e.g., cell-based and multiplexed platforms, to screen for small molecule drugs that inhibit enzymes such as...
2017/0306386 YEAST SCREENS FOR TREATMENT OF HUMAN DISEASE
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and...
2017/0306385 METHODS FOR DISCOVERING THERAPEUTICS THAT ALTER THE STABILITY OF TARGET PROTEINS
The present application relates, in some aspects, to screening methods to identify test compounds that stabilize or destabilize a protein of interest. The...
2017/0306384 KIT COMPRISING ATP-DIPHOSPHOHYDROLASE FOR DETECTING BACTERIAL ATP IN A SAMPLE
A kit for detecting bacterial ATP in a sample is provided. The kit comprises an aqueous composition having a pH of about 6.0 to 7.2. The aqueous composition...
2017/0306383 BIOSENSOR
According to one embodiment, a biosensor includes a substrate and a sensor matrix that is present in a two-dimensional region on the substrate. The sensor...
2017/0306382 3-Alpha-Hydroxysteroid Dehydrogenase Mutants and Process for the Preparation of Ursodeoxycholic Acid
The invention relates to novel 3-hydroxysteroid dehydrogenase mutants, to the sequences which code for these enzyme mutants, to processes for the preparation...
2017/0306381 CELL LINES
There is provided inter alia a process for stabilizing a eukaryotic cell line which expresses PylRS and tRNAPyl and which is suitable for incorporation of a...
2017/0306380 AMINO ACID DERIVATIVES
There are provided amino acid derivatives of formula V and VI as defined herein which are pyrrolysine analogs for use in bioconjugation processes.
2017/0306379 De-mannosylation of phosphorylated N-glycans
Methods for demannosylating phosphorylated N-glycans on a glycoprotein are described that use a mannosidase capable of hydrolyzing a terminal alpha-1,2 mannose...
2017/0306378 PROTEIN PRODUCTION METHOD
This invention relates to a method for producing a protein of interest, comprising introducing a protein expression vector which comprises a gene fragment a...
2017/0306377 STEVIOL GLYCOSIDE PRODUCTION
The present invention relates to a method for increasing the degree of glycosylation of a composition comprising steviol glycosides, which method comprises: ...
2017/0306376 Methods and Materials for Recombinant Production of Saffron Compounds
Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a zeaxanthin cleavage dioxygenase alone or in...
2017/0306374 PRODUCTION OF GLUCAN POLYMERS FROM ALTERNATE SUCROSE SOURCES
Reaction solutions are disclosed herein comprising water, incompletely refined sucrose, and a glucosyltransferase enzyme that synthesizes insoluble poly...
2017/0306373 Alpha (1,3) Fucosyltransferases For Use In The Production of Fucosylated Oligosaccharides
The invention relates to methods and compositions for the production of fucosylated oligosaccharides.
2017/0306372 METHOD OF PREPARING SUGAR SOLUTION
A method prepares a sugar solution from cellulose-containing biomass. The method includes step (1): a step of obtaining an endoxylanase hydrolysate by...
2017/0306371 METHOD FOR PRODUCING TREHANGELIN
An object of the present invention is to provide enzymes and a DNA encoding the enzymes that are involved in biosynthesis of trehangelin which has the...
2017/0306370 COMPOSITION FOR PREPARING TAGATOSE AND METHOD FOR PREPARING TAGATOSE FROM FRUCTOSE
The present invention relates to a composition for preparing tagatose, wherein the composition is used for preparing tagatose from fructose and contains a...
2017/0306369 Method for Surfactant enhanced Enzymatic Hydrolysis
A method for producing fermentable sugars from paper is described. The method comprises the steps of preparing an aqueous paper slurry, treating the paper...
2017/0306368 METHODS FOR THAXTOMIN PRODUCTION AND MODIFIED STREPTOMYCES WITH INCREASED THAXTOMIN PRODUCTION
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in some aspects,...
2017/0306367 METHOD FOR MANUFACTURING CIS-5-HYDROXY-L-PIPECOLIC ACID
A method for producing cis-5-hydroxy-L-pipecolic acid, the method comprising allowing a 2-oxoglutarate-dependent L-pipecolic acid hydroxylase to act on...
2017/0306366 USE OF INDUCIBLE PROMOTERS IN THE PRODUCTION OF METHIONINE
The present invention relates to use of inducible promoters in the production of methionine by fermentation. The present invention concerns a method for the...
2017/0306365 PROCESS FOR PRODUCING A PUFA-CONTAINING FEEDSTUFF BY EXTRUDING A PUFA-CONTAINING BIOMASS
In accordance with the invention, it was found, surprisingly, that a polyunsaturated fatty acids (PUFAs)-comprising biomass with other feedstuff components can...
2017/0306364 METHOD FOR THE ENRICHMENT OF MICROALGAE BIOMASS IN POLYUNSATURATED FATTY ACIDS
Process for enriching microalgal biomass, in particular of the genus Nannochloropsis, with different polyunsaturated fatty acids, primarily docosahexaenoic...
2017/0306363 METABOLIC ENGINEERING FOR ENHANCED SUCCINIC ACID BIOSYNTHESIS
Presented herein are biocatalysts and methods for the production of succinic acid from carbon sources. The biocatalysts include microbial cells that have been...
2017/0306362 BIOCATALYTIC METHODS TO CONVERT CYCLOHEXANE OXIDATION PROCESS WASTE STREAMS TO USEFUL PRODUCTS
The invention relates to methods for enriching monomer content in a cycloalkane oxidation process mixed organic waste stream. In particular, the methods...
2017/0306361 ENHANCED EFFICIENCY ETHANOL AND SUGAR CONVERSION PROCESSES
Overlay processes are disclosed for making ethanol that not only increase ethanol conversion but do so in a cost effective manner with a reduction in energy...
2017/0306360 METHOD FOR PRODUCING ALCOHOL BY USE OF A TRIPEPTIDYL PEPTIDASE
The present invention provides a method for producing an alcohol comprising: (a) admixing a tripeptidyl peptidase, predominantly having exopeptidase activity,...
2017/0306359 CONTINUOUS PROCESS FOR TREATING A LIGNOCELLULOSIC BIOMASS
It is disclosed a continuous process for soaking a ligno-cellulosic biomass stream in an extraction solution comprising water and dissolved water soluble...
2017/0306358 COMPOSITIONS AND METHODS FOR BIOLOGICAL PRODUCTION OF BUTANE-BASED COMPOUNDS FROM A C1 SUBSTRATE
The present disclosure relates to biosynthetic methods for producing propylene from C.sub.1 substrates (e.g., methane, methanol, carbon monoxide, syngas) and...
2017/0306357 PROCESS FOR OBTAINING A CEMENTITIOUS MINERAL SUBSTANCE
The invention relates to a method for obtaining a mineral substance from a base comprising mineral matter, the method comprising obtaining the base comprising...
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