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Patent # Description
2017/0304328 PHARMACEUTICAL COMPOSITION HAVING IMPROVED CONTENT UNIFORMITY
This present invention relates to pharmaceutical compositions comprising cyclophosphamide alone and/or in combination with one or more pharmaceutical active...
2017/0304327 CANNABINOID RECEPTOR MODULATORS
Provided are certain methods useful in the treatment of cancer comprising administering a compound of Formula Ia and pharmaceutical compositions thereof that...
2017/0304326 PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO DAMAGE
The purpose of the present invention is to identify a migratory factor that guides pluripotent stem cells (Muse cells) useful in new medical applications to...
2017/0304325 TREATMENT OF RHEUMATOID ARTHRITIS
A composition for treating chronic inflammation, including an antibiotic, a lipophilic potentiating agent, a guanosine analog antiviral agent, and Vitamin D in...
2017/0304324 METHOD FOR OBTAINING VITAMIN D2 FROM SHIITAKE MUSHROOMS
A method of obtaining vitamin D from shiitake includes a) adding ethanol to shiitake powder, followed by reflux extraction, to prepare a shiitake extract; and...
2017/0304323 CONTROLLED RELEASE AND TASTE MASKING ORAL PHARMACEUTICAL COMPOSITIONS
The invention relates to tablet comprising granules dispersed in at least one hydrophilic compound or matrix. The granules contain an active agent, at least...
2017/0304322 CONTROLLED RELEASE AND TASTE MASKING ORAL PHARMACEUTICAL COMPOSITIONS
The invention relates to tablet comprising granules dispersed in at least one hydrophilic compound or matrix. The granules contain an active agent, at least...
2017/0304321 NEUROACTIVE COMPOUNDS AND METHODS OF USE THEREOF
Methods for treating a subject suffering from a sterol synthesis disorder or a sterol deficiency disorder, e.g., Smith-Lemli-Opitz syndrome, the method...
2017/0304320 EXTENDED-RELEASE DRUG DELIVERY COMPOSITIONS
An extended-release drug delivery composition and method of administering the same is provided. The composition comprises microspheres loaded with a...
2017/0304319 DEXAMETHASONE ORAL FILM
The present invention relates to an oral film consisting essentially of dexamethasone and hydroxypropyl methylcellulose, wherein the concentration of...
2017/0304318 17A,21-DIESTERS OF CORTEXOLONE FOR USE IN THE TREATMENT OF TUMORS
The present invention provides certain cortexolone derivatives of formula (I) and the same for use as antitumor active ingredients for the curative or...
2017/0304317 DIETARY SUPPLEMENTS FOR MUSCLE GROWTH AND STRENGTH
A compound is provided for oral administration of dehydroepiandrosterone (DHEA) derivatives to a human so as to improve at least one of adrenal hormonal...
2017/0304316 Ophthalmic Solution
Disclosed herein an ophthalmic formulation comprises carbonic anhydrase inhibitor(s) alone, in an aqueous solution or a combination of two intraocular pressure...
2017/0304315 USE OF CDK9 AND BRD4 INHIBITORS TO INHIBIT INFLAMMATION
Provided are methods for the combined use of cyclin-dependent kinase 9 (CDK9) inhibitors and bromodomain containing 4 (BRD4) inhibitors to reduce, inhibit...
2017/0304314 DOSAGE REGIMENT OF FERRIC MALTOL
The present invention relates to a dosage regimen of ST10 (ferric maltol) for use in the treatment of patients suffering from iron deficiency with or without...
2017/0304313 Therapeutic Combination For The Treatment Of Cancer
This invention relates to a pharmaceutical combination comprising (a) an EGFR inhibitor and (b) a FGFR inhibitor, particularly for use in the treatment of a...
2017/0304312 2-Amino-6-Methyl-4,4a,5,6-Tetrahydropyrano[3,4-d][1,3]Thiazin-8a(8H)-yl-1,- 3-Thiazol-4-yl Amides
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds...
2017/0304311 Pharmaceutical Combinations
A pharmaceutical combination comprising: (a) a phosphatidylinositol-3-kinase inhibitor selected from ...
2017/0304310 METHODS AND COMPOSITIONS FOR THE INHIBITION OF PIN1
The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels.
2017/0304309 CAFFEINE FOR THE TREATMENT OF MYOTONIC DYSTROPHY TYPE 1 AND TYPE 2
The present invention relates to caffeine for use in the treatment of myotonic dystrophy type 1 and type 2. The present invention also relates to compositions...
2017/0304308 Compositions and Methods for the Delivery of Therapeutics
The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.
2017/0304307 TOFACITINIB ORALLY DISINTEGRATING TABLETS
The present invention relates to Orally Disintegrating Tablets (ODT) of Tofacitinib and its pharmaceutically acceptable salts and the process to produce the...
2017/0304306 SELECTIVE NaV1.7 INHIBITORS FOR THE TREATMENT OF DIABETES
Provided herein are methods for treating or preventing prediabetes or diabetes, or maintaining or lowering blood or plasma glucose or maintaining or lowering...
2017/0304305 QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF
The invention relates to quinazoline derivatives substituted by aniline which are represented by the below formula (I), pharmaceutical acceptable salts and...
2017/0304304 THERAPEUTIC COMPOUNDS
The invention provides a compound of formula I: ##STR00001## wherein X, Y, Z have any of the values defined in the specification or a salt thereof. The...
2017/0304303 Novel Pyrimidinyl-DiazoSpiro Compounds
The invention relates to spiro deriviatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium...
2017/0304302 Compounds for Treatment of Cancer
The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present...
2017/0304301 TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION
The present invention relates to methods for treating Neisseria gonorrhoeae infection which comprises administering to a subject in need thereof novel...
2017/0304300 HIF-2alpha INHIBITORS FOR TREATING IRON OVERLOAD DISORDERS
The present disclosure relates to HIF-2.alpha. inhibitors and methods of making and using them for treating iron overload disorders. Certain compounds were...
2017/0304299 OXAZOLINE AND ISOXAZOLINE DERIVATIVES AS CRAC MODULATORS
The present invention relates to compounds of Formula (I) along with processes for their preparation that are useful for treating, preventing and/or managing...
2017/0304298 COMPOSITIONS AND METHODS FOR INCREASING THE METABOLIC LIFETIME OF DEXTROMETHORPHAN AND RELATED PHARMACODYNAMIC...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
2017/0304297 IMMEDIATE RELEASE ABUSE DETERRENT TABLET
The invention relates to an abuse deterrent immediate release tablet.
2017/0304296 NOVEL PHARMACEUTICAL FORMULATION
The present invention is directed to a pharmaceutical composition comprising a pharmaceutically effective amount of guaifenesin, naproxen and at least one...
2017/0304295 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are...
2017/0304294 USE OF NALMEFENE IN NON-ALCOHOLIC STEATOHEPATITIS
The present invention relates to new medical uses of morphinans such as nalmefene and naltrexone and their related derivatives, pharmaceutical formulations...
2017/0304293 COORDINATED METABOLIC REPROGRAMMING IN RESPONSE TO PRODUCTIVE VIRAL INFECTIONS
The invention generally relates to methods of treating viral infections using known drugs and pharmaceutical compositions comprising same. More specifically,...
2017/0304292 Tetrahydroisoquinoline Derivatives
The present invention relates to tetrahydroisoquinoline derivatives according to formula (I), which are Positive Allosteric Modulators of D1 and accordingly of...
2017/0304291 METHODS OF TREATING CANCER PATIENTS WITH FARNESYLTRANSFERASE INHIBITORS
The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods of treating a...
2017/0304290 QUINOLINE DERIVATIVE AGAINST NON-SMALL CELL LUNG CANCER
The present application provides a quinoline derivative against non-small cell lung cancer. ...
2017/0304289 COMBINATIONS COMPRISING SIPONIMOD AND LAQUINIMOD FOR THE TREATMENT OF MULTIPLE SCLEROSIS
The present invention relates to combinations and pharmaceutical compositions comprising siponimod and laquinimod, and the use of said combinations and/or...
2017/0304288 Formulations of Methionine Aminopeptidase Inhibitors for Treating Infectious Diseases
Provided herein are formulations and co-solvent formulations and methods for treating an infectious disease utilizing the same. The formulations and co-solvent...
2017/0304287 PHARMACEUTICAL COMBINATION COMPOSITION COMPRISING COMPLEX FORMULATIONS OF IVACAFTOR AND LUMACAFTOR AND THEIR...
Disclosed herein is a pharmaceutical combination composition comprising stable complexes with controlled particle size, increased apparent solubility and...
2017/0304286 NEW INDICATION OF PAROXETINE PHARMACEUTICAL COMPOSITION FOR TREATING CANCER
A method for treating a cancer includes administering to a subject in need thereof a pharmaceutical composition containing a therapeutically effective amount...
2017/0304284 Therapeutic inhibitor for EBV-associated tumor with tailor responsive optical imaging
This invention provides a nucleus-permeable small-molecule inhibitor, L.sub.2P.sub.4 (where L.sub.2 is 4-(4-(Diethylamino)styryl)-N-carboxymethylpyridinium...
2017/0304283 COMPOUNDS AND COMPOUNDS FOR USE IN METHODS FOR TREATING DISEASES OR CONDITIONS MEDIATED BY PROTEIN DISULFIDE...
The invention provides compounds of formula (I) that inhibit PDI, for use in methods to treat or prevent a disease or condition in a subject that would benefit...
2017/0304282 FORMULATIONS OF AN LSD1 INHIBITOR
The present application relates to pharmaceutical formulations and dosage forms of a lysine specific demethylase-1 (LSD1) inhibitor, or a pharmaceutically...
2017/0304281 METHODS OF USING POTASSIUM CHANNEL INHIBITORS (BLOCKERS) FOR FLUID RESUSCITATION
Methods and pharmaceutical treatments of fluid resuscitation in which a selective potassium channel inhibitor is administered to a patient in a therapeutic...
2017/0304280 SYNERGISTIC COMBINATIONS STIMULATING THE EXPRESSION OF SIRTUIN 1
The invention discloses synergistic compositions stimulating the expression of Sirtuin comprising combinations of a first component selected from berberine and...
2017/0304279 PHOSPHOINOSITIDE 3-KINASE INHIBITOR WITH A ZINC BINDING MOIETY
The invention provides a compound of Formula I, ##STR00001## Pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment...
2017/0304278 HETEROARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE
The present application relates to novel heteroaryl-substituted imidazo[1,2-a]pyridines, to processes for preparation thereof, to the use thereof, alone or in...
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