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Patent # Description
2017/0304277 TETRAHYDROPYRAZOLOPYRIDINE DERIVATIVES AS GHRELIN RECEPTOR AGONISTS
The present invention relates to novel compounds of a formula (I) or a pharmaceutically acceptable salt or solvate thereof, processes for their preparation,...
2017/0304276 AN INHALABLE RAPAMYCIN FORMULATION FOR THE TREATMENT OF PULMONARY HYPERTENSION
The present invention relates to methods and compositions for the treatment and prophylaxis of pulmonary arterial hypertension (PAH) in a human subject in need...
2017/0304275 METHODS FOR DOSING AN ORALLY ACTIVE 1,2,4-OXADIAZOLE FOR NONSENSE MUTATION SUPPRESSION THERAPY
The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases...
2017/0304274 DYSLIPIDEMIA THERAPEUTIC AGENT
This invention provides a combination-drug composition and a combination use of pharmaceuticals for preventing and/or treating dyslipidemic conditions such as...
2017/0304273 DYSLIPIDEMIA THERAPEUTIC AGENT
This invention provides a combination-drug composition and a combination use of pharmaceuticals for preventing and/or treating dyslipidemic conditions such as...
2017/0304272 ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF
The present invention provides compounds of Formula I, ##STR00001## pharmaceutical compositions comprising these compounds and methods of using these compounds...
2017/0304271 ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF
The present invention provides compounds of Formula I, ##STR00001## pharmaceutical compositions comprising these compounds and methods of using these compounds...
2017/0304270 ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF
The present invention provides compounds of Formula I: ##STR00001## pharmaceutical compositions comprising these compounds and methods of using these compounds...
2017/0304269 METHOD FOR TREATING NEURODEGENERATIVE DISEASES
The present invention is directed to a method for treating a neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer disease,...
2017/0304268 OPIOID RECEPTOR MODULATOR DOSAGE FORMULATIONS
Abuse deterrent solid dosage formulations containing 5-({[2-Amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-- ...
2017/0304267 Use of an Acetylcholinesterase Inhibitor and Idalopirdine for Reducing Falls in Parkinson's Disease Patients
The present invention relates to the use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in patients suffering from a CNS disease, in...
2017/0304266 (3aR)-1,3a,8-Trimethyl-1 ,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl Phenylcarbamate and Methods of Treating...
The invention includes an amount of (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl phenylcarbamate for administering to a subject and...
2017/0304265 Paroxysmal Extreme Pain Disorder Treatment
The present invention is directed to the treatment of paroxysmal extreme pain disorder (PEPD) comprising administering to a subject in need thereof, a...
2017/0304264 Novel Erythromelalgia Treatment
The present invention is directed to the treatment of erythromelalgia comprising administering to a subject in need thereof, a therapeutically effective amount...
2017/0304263 ANTIOXIDATIVE STRESS COMPOSITIONS, METHODS OF PREPARING AND USES THEREOF
Antioxidative stress compositions, methods of using antioxidative stress composition and methods of preparing antioxidative stress composition compositions are...
2017/0304262 SGLT-2 INHIBITORS FOR TREATING METABOLIC DISORDERS IN PATIENTS WITH RENAL IMPAIRMENT OR CHRONIC KIDNEY DISEASE
The present invention relates to certain SGLT-2 inhibitors, such as ertugliflozin or a co-crystal or a pharmaceutically acceptable salt thereof, for treating...
2017/0304261 SILVESTROL, SILVESTROL ANALOGS AND USES THEREOF
Disclosed herein are treatment methods, vaccination methods, compositions, co-therapeutic methods, combination therapeutic compositions and kits comprising...
2017/0304260 ALTRENOGEST FORMULATION AND USES THEREOF FOR ESTRUS SYNCHRONISATION IN ANIMALS
The invention relates to a microsphere composition comprising (a) a microsphere material; and (b) a lipidic liquid formulation comprising (i) an effective...
2017/0304259 COMPOSITION
The present invention relates to a composition for use in the treatment of an intestinal tract disorder caused by a gluten-associated protein, said composition...
2017/0304258 NANOPARTICLE ISOFLAVONE COMPOSITIONS & METHODS OF MAKING AND USING THE SAME
The present invention is directed to formulations of genistein and methods for making and using the same. In particular embodiments, the formulations described...
2017/0304257 TOPICAL OILY FOAM COMPOSITIONS
Topical alcohol-free thermo labile oily foam composition comprising (i) at least one active pharmaceutical ingredient or ectoparasitic active ingredient;...
2017/0304256 TREATMENT OF CIRCADIAN RHYTHM DISORDERS
Embodiments of the invention relate to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light...
2017/0304255 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
Provided herein are compounds of formula (I) useful for the treatment of PPAR-delta related diseases (e.g. mitochondrial diseases, muscular diseases, vascular...
2017/0304254 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators...
2017/0304253 Laquinimod Combination Therapy For Treatment Of Multiple Sclerosis
The subject invention provides a method for treating a subject afflicted with a form of multiple sclerosis (MS) or presenting a clinically isolated syndrome...
2017/0304252 AZELAIC ACID ESTERS IN THE TREATMENT OF INSULIN RESISTANCE
A method of treating insulin resistance includes administering to a subject a pharmaceutical composition comprising diethyl azelate. For example, a method of...
2017/0304251 AVOCADO-DERIVED LIPIDS FOR USE IN TREATING LEUKEMIA
A method of treating a leukemia comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising a compound...
2017/0304250 Uses of Chlorogenic Acid in the Preparation of Medicaments for Treatment of Mesoglioma
The present invention provides uses of chlorogenic acid in the preparation of medicaments for treatment of mesoglioma. Chlorogenic acid according to the...
2017/0304249 EMULSION AND EMULSION PRECONCENTRATE COMPOSITIONS COMPRISING OMEGA-3 FATTY ACIDS AND USES THEREOF ARE DISCLOSED
Novel compositions comprising omega-3 fatty acids and uses thereof are disclosed.
2017/0304248 DIETARY EMULSION FORMULATIONS AND METHODS FOR USING THE SAME
Disclosed herein is a formulation that can take the form of an emulsion which contains total enteral or parenteral nutrition for a recipient subject. The...
2017/0304247 EICOSAPENTAENOIC ACID (EPA) FORMULATIONS
Provided herein are compositions comprising eicosapentaenoic acid (EPA) and polar lipids (e.g., glycolipids and phospholipids), and which do not contain any...
2017/0304246 SOLID PHARMACEUTICAL PREPARATION CONTAINING LEVOTHYROXINE
The invention relates to a solid pharmaceutical preparation comprising levothyroxine sodium, gelatine, citric acid and a filler. The solid pharmaceutical...
2017/0304245 COMPOUNDS FOR THE TREATMENT OF OBESITY AND METHODS OF USE THEREOF
Pentacyclic triterpene weight loss agents are provided herein. Also provided are pharmaceutical formulations containing a therapeutically effective amount of...
2017/0304244 COMPOSITION FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASES, CONTAINING RAMALIN
The present invention relates to a neurodegenerative disease treatment use, which is a novel use of Ramalin, and, more specifically, to a composition for...
2017/0304243 New Therapy for Transthyretin-Associated Amyloidosis
It is provided a catechol-O-methyltransferase (COMT) inhibitor for use in the prevention and/or treatment of transthyretin-associated amyloidosis. It is also...
2017/0304242 BACLOFEN FORMULATIONS AND METHODS FOR MAKING SAME
Methods for preparing sterilized baclofen solutions include adjusting the pH to below a desired pH, and steam sterilizing the solution with adjusted pH, which...
2017/0304241 PERK ACTIVATOR FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
The present invention relates to a novel method for the treatment and/or prophylaxis of a tau-mediated neurodegenerative disease and/or of a tau-mediated...
2017/0304240 NOVEL COMPOUNDS SUPPORTS HEMATOPOIETIC STEM CELLS AND RED BLOOD CELLS
The present disclosure relates to methods of using a compound to induce regeneration of hematopoietic stem cells or increase the recovery of red blood cells....
2017/0304239 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV)...
2017/0304238 COMPOSITION FOR REDUCING FREQUENCY OF URINATION, METHOD OF MAKING AND USE THEREOF
Pharmaceutical compositions for reducing frequency of urination are disclosed. The pharmaceutical compositions comprise one or more prostaglandin pathway...
2017/0304237 Necrosis Inhibitors
The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides,...
2017/0304236 ANTIALLERGIC AGENT
An object to be achieved by the present invention is to provide a novel antiallergic agent using, as an active ingredient, a compound that has heretofore not...
2017/0304235 LINEAR GUANIDINE DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF
The present invention relates to linear guanidine derivatives, methods of preparation, uses and pharmaceutical compositions thereof. The compounds of Formulas...
2017/0304234 EXTENDED RELEASE LIQUID COMPOSITIONS OF METFORMIN
The present invention relates to extended release liquid compositions of metformin. The extended release liquid compositions are in the form of suspensions or...
2017/0304233 METHODS OF TREATING NON-ALCOHOLIC STEATOHEPATITIS (NASH) USING CYSTEAMINE PRODUCTS
The disclosure relates, in general, to treatment of fatty liver disorders comprising administering compositions comprising cysteamine products. The disclosure...
2017/0304232 Endoxifen For Local Transdermal Therapy To The Breast
Disclosed are methods and topical formulations for treating and/or preventing cell proliferative diseases and disorders including breast cancer and ductal...
2017/0304231 METHODS OF DIAGNOSIS AND TREATMENT
A method for diagnosing a cardiac ischemic event and a kit for detecting biomarkers used in the method. Also provided is a method for treating a PPAR-related...
2017/0304230 COMPOSITIONS AND METHODS FOR INCREASING THE METABOLIC LIFETIME OF DEXTROMETHORPHAN AND RELATED PHARMACODYNAMIC...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
2017/0304229 COMPOSITIONS AND METHODS FOR INCREASING THE METABOLIC LIFETIME OF DEXTROMETHORPHAN AND RELATED PHARMACODYNAMIC...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
2017/0304228 NEW INDICATION OF CINACALCET HCL PHARMACEUTICAL COMPOSITION FOR TREATING CANCER
A method for treating a cancer includes administering to a subject in need thereof a pharmaceutical composition containing a therapeutically effective amount...
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