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Patent # Description
2017/0314060 DIGITAL POLYMERASE FIDELITY ASSAY
Methods of determining polymerase fidelity are provided. In one embodiment, the method comprises filling a gapped plasmid with a polymerase to form a...
2017/0314059 METHODS AND ARTICLES FOR DETECTING DEOXYRIBONUCLEASE ACTIVITY
The disclosure provides articles and methods useful for detecting a discrete source of DNase activity. DNase-producing microorganisms can be detected. The...
2017/0314058 Determination of Ligninases Activities by Nano-structure Initiator Mass Spectrometry
A method for rapid, high throughput screening of the activities of enzymes, especially ligninases and its enzyme cocktails, using nanostructure initiator mass...
2017/0314057 METHOD, DEVICE AND SYSTEM FOR TESTING DRUG SENSITIVITY
When bacteria growth is determined in the related art using an ATP method, the bacteria growth is determined, based on an increase or a decrease in live...
2017/0314056 METHOD OF USING NEAR INFRARED FLUORESCENT DYES FOR IMAGING AND TARGETING CANCERS
The present invention describes methods of identifying, detecting, imaging, isolating and locating cancer cells in a subject. The method involves the use of...
2017/0314055 ENZYMATIC ONE-POT REACTION FOR DOUBLE POLYPEPTIDE CONJUGATION IN A SINGLE STEP
Herein is reported a method for producing an enzymatic conjugation product of three polypeptides comprising the simultaneous incubation of i) a first...
2017/0314054 IDENTIFICATION OF TRANSGLUTAMINASE SUBSTRATES AND USES THEREFOR
According to one aspect, the present disclosure provides a method of identifying a substrate of a transglutaminase using a peptide array comprising a plurality...
2017/0314053 METHOD AND SYSTEM FOR THE PRODUCTION OF RECOMBINANT PROTEINS BY CELLS
A cassette sequence for the transformation of a host cell includes at least: a first nucleotide sequence encoding a peptide or protein of interest to be...
2017/0314052 A SUCROSE PHOSPHORYLASE FOR THE PRODUCTION OF KOJIBIOSE
The present invention relates to the production of the disaccharide kojibiose which is known to be a powerful prebiotic. The invention indeed discloses the...
2017/0314051 METHOD OF PRODUCING SUGAR SOLUTION AND XYLOOLIGOSACCHARIDE
A method of producing a sugar liquid and a xylooligosaccharide includes Steps (1) to (3): Step (1): hydrolyzing a cellulose-containing biomass with a...
2017/0314050 ENZYMATIC HYDROLYSIS OF DISACCHARIDES AND OLIGOSACCHARIDES USING ALPHA-GLUCOSIDASE ENZYMES
A method is disclosed for hydrolyzing an alpha-1,3 or alpha-1,6 glucosyl-glucose linkage in a saccharide (disaccharide or oligosaccharide). This method...
2017/0314049 Methods and Materials for Biosynthesis of Manoyl Oxide
The invention relates to recombinant microorganisms and methods for producing manoyl oxide.
2017/0314048 HETEROTROPHICALLY CULTIVATED RECOMBINANT MICROALGAE
Disclosed herein are methods of manufacturing renewable chemicals through the manufacture of novel triglyceride oils followed by chemical modification of the...
2017/0314047 METHOD FOR THE PRODUCTION OF ALKYL ESTERS
A method of producing biodiesel includes reacting at least one of brown grease and FOG with at least one enzyme, alcohol, and an aqueous solution to produce a...
2017/0314046 METHOD AND DEVICE FOR TREATING BIOMASS AND ORGANIC WASTE
The present invention provides a method for treatment of biomass material by fermentation, said method comprises a pre-treatment of the biomass material by...
2017/0314045 MICROBIAL PROCESSING OF GASES
The present invention relates to methods and apparatus for microbial conversion of carbon dioxide, carbon monoxide and hydrogen to methane, and to the...
2017/0314044 ADENOVIRUS CONSTRUCTS AND METHODS
This disclosure describes oncolytic adenovirus constructs and methods on using the constructs. Generally, the oncolytic constructs includes at least a partial...
2017/0314043 RECOMBINANT ARTERIVIRUS REPLICON SYSTEMS AND USES THEREOF
The present disclosure generally relates to viral-based expression systems suitable for the production of molecule of interests in recombinant host cells. The...
2017/0314042 GENETICALLY MODIFIED MSC AND THERAPEUTIC METHODS
This disclosure relates to vectors, isolated cells, compositions, and methods for the treatment of critical limb ischemia and associated disorders. One aspect...
2017/0314041 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF
The present invention provides, among other things, multimeric coding nucleic acids that exhibit superior stability for in vivo and in vitro use. In some...
2017/0314040 FUSARIUM CHITIN SYNTHASE GENE Chs3b AND THE USE THEREOF
The present invention discloses RNAi constructs derived from a Fusarium chitin synthase gene Chs3b, which has a nucleotide sequence as shown by SEQ ID NO: 1....
2017/0314039 PHYTOPHTHORA RESISTANT PLANTS BELONGING TO THE SOLANACEAE FAMILY
The present invention relates to a plant belonging to the Solanaceae family wherein said plant comprises a genetic trait providing Phytophthora resistance and...
2017/0314038 OPTIMIZED THIONIN PROTECTS PLANTS AGAINST BACTERIAL INFECTIONS
Two small proteins with anti-bacterial activity are generated and called optimized thionin and optimized pro-thionin. Optimized pro-thionin contains a signal...
2017/0314037 Isolated Novel Nucleic Acid and Protein Molecules from Corn and Methods of Using Those Molecules to Generate...
This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of...
2017/0314036 Methods for Monocot Plant Improvement
The invention provides methods and materials for increasing at least one of root biomass and above-ground biomass and in a Poaceae plant by expressing a PEAPOD...
2017/0314035 WHEAT WITH INCREASED RESISTANT STARCH LEVELS
A series of independent human-induced non-transgenic mutations found at one or more of the SBEII genes of wheat; wheat plants having these mutations in one or...
2017/0314034 WHEAT WITH INCREASED RESISTANT STARCH LEVELS
A series of independent human-induced non-transgenic mutations found at one or more of the SBEII genes of wheat; wheat plants having these mutations in one or...
2017/0314033 HERBICIDE-RESISTANT TARAXACUM KOK-SAGHYZ AND TARAXACUM BREVICORNICULATUM
The invention provides the genetically manipulated herbicide-resistant rubber producing dandelion plants and seed of said plants. Another aspect of the...
2017/0314032 Plastid Transformation of Maize
A method is provided for transforming monocotyledonous plants to express DNA sequences of interest from plant cell plastids. The method allows the ...
2017/0314031 COMPACT AND OPTIMIZED METABOLIC PATHWAY DESIGN IN PICHIA PASTORIS
The present invention relates to an optimized metabolic pathway design in P. pastoris. In particular, to a recombinant polycistronic expression construct for...
2017/0314030 BETA-CATENIN NUCLEIC ACIDS AND USES THEREOF
Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against CTNNB1. Also described herein include methods for treating...
2017/0314029 OLIGONUCLEOTIDE SEQUENCE FOR USE IN PATHWAY ENGINEERING
The present invention comprises a novel artificial oligonucleotide sequence which can initiate the transcription of a gene under various conditions at a high...
2017/0314028 MODULATORY POLYNUCLEOTIDES
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of modulatory polynucleotides.
2017/0314027 INCREASING ATOH1 LIFE TO DRIVE SENSORINEURAL HAIR CELL DIFFERENTIANTION
The present disclosure provides compositions and methods for treating subjects at risk for or with sensorineural hearing loss by modulating the rate of Atoh1...
2017/0314026 MODULATION OF PREKALLIKREIN (PKK) EXPRESSION
Disclosed herein are antisense compounds and methods for decreasing PKK mRNA and protein expression. Such methods, compounds, and compositions are useful to...
2017/0314025 MODIFIED TGF-BETA OLIGONUCLEOTIDE FOR USE IN A METHOD OF PREVENTING AND/OR TREATING AN OPHTHALMIC DISEASE
The invention refers to an oligonucleotide consisting of 10 to 20 nucleotides of selected regions of the TGF-beta1, TGF-beta2 or TGF-beta3 nucleic acid...
2017/0314024 DIRECT AND SELECTIVE INHIBITION OF MDM4 FOR TREATMENT OF CANCER
The present application relates to the field of cancer, particularly that of cancers with high MDM4 protein levels (such as melanoma, breast, colon or lung...
2017/0314023 MATRIPTASE INHIBITORS AND USES THEREOF AGAINST ORTHOMYXOVIRIDAE INFECTIONS
The present invention provides matriptase inhibitors and compositions for treating and preventing orthomyxovirus infections such as flue infections. The...
2017/0314022 COMBINATION LONG ACTING COMPOSITIONS AND METHODS FOR HEPATITIS C
The present Invention relates to pharmaceutical compositions useful in the treatment or prevention or cure of viral infections, such as HCV infections, and...
2017/0314021 AGENT FOR TREATING FIBROSIS OF THE INTESTINE
The present invention relates to a carrier for delivering a substance to extracellular matrix-producing cells in the intestine, the carrier containing a...
2017/0314020 MICRORNA-200 BASED APPROACHES FOR MODULATING BONE FORMATION INHIBITION AND BONE REGENERATION
In certain embodiments, the present invention provides the use of microRNA (miR)-200a and/or miR-200c to inhibit ossification and bone formation. In certain...
2017/0314019 MICRORNA COMPOSITIONS AND METHODS OF MAKING AND USING SAME
A method comprising administering to a subject a composition comprising an isolated microRNA having a sequence selected from the group consisting of miR-19a-3p...
2017/0314018 An LncRNA and oncolytic adenovirus, and application thereof
Provided are an LncRNA and oncolytic adenovirus, and application thereof. The oncolytic adenovirus is used as a carrier to express the LncRNA, so as to express...
2017/0314017 miRNA TRANSCRIPTOME METHODS AND COMPOSITIONS
Methods, polynucleotides, kits, and reaction mixtures are disclosed for the enriching of short polynucleotide molecules that have a length within a desired...
2017/0314016 METHOD FOR RGEN RNP DELIVERY USING 5'-PHOSPHATE REMOVED RNA
Provided are a composition for ribonucleoprotein delivery, comprising a guide RNA free of 5'-terminal phosphates, and a method for ribonucleoprotein delivery,...
2017/0314015 CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING SICKLE CELL DISEASE
CRISPR/CAS-related compositions and methods for treatment of Sickle Cell Disease (SCD) are disclosed.
2017/0314014 Methods for Genome Assembly, Haplotype Phasing, and Target Independent Nucleic Acid Detection
The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure provides methods for haplotype phasing and...
2017/0314013 SYSTEM FOR PRODUCTION OF ANTIBODIES AND THEIR DERIVATIVES
The present disclosure provides methods and compositions for the production of chimeric antibodies that specifically bind an antigen of interest.
2017/0314012 MULTI-CHAIN EUKARYOTIC DISPLAY VECTORS AND USES THEREOF
A eukaryotic expression vector capable of displaying a multi-chain polypeptide on the surface of a host cell is provided, such that the biological activity of...
2017/0314011 CLONING METHOD
The present invention relates to a method based on the use of restriction enzyme digestion and ligation via the cleavage sites, thereby to prepare two or more...
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