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Patent # Description
2017/0321292 COLD TREATMENT FOR IMPROVING THE LOAD-BEARING CAPACITY OF METALLIC COMPONENTS
A method for producing a metallic component, The method includes the method steps of first machining (103) the component and thereafter cooling (105) the...
2017/0321291 A METHOD FOR THE MANUFACTURE OF AN EFFICIENT STEEL DEOXIDIZER ALUMINUM MATRIX COMPOSITE MATERIAL
A method of manufacture to provide an efficient and economical steel deoxidizer aluminum matrix composite material that is near fully dense, free of brittle...
2017/0321290 DNA IMPURITIES IN A COMPOSITION COMPRISING A PARVOVIRAL VIRION
The current invention relates to nucleic acid impurities in a composition comprising a parvoviral vector. In particular, the current invention shows that DNA...
2017/0321289 NON-REPLICATIVE TRANSDUCTION PARTICLES AND TRANSDUCTION PARTICLE-BASED REPORTER SYSTEMS
Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The...
2017/0321288 Predicting Productivity In Early Cell Line Development
The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting...
2017/0321287 METHODS FOR MEASURING ENZYME ACTIVITY USEFUL IN DETERMINING CELL VIABILITY IN NON-PURIFIED SAMPLES
An assay kit of reagents including a nucleic acid capable of acting as substrate for polymerase microorganism activity useful in a method of detecting...
2017/0321286 DETECTION OF LUNG NEOPLASIA BY AMPLIFICATION OF RNA SEQUENCES
Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the...
2017/0321285 NLRC5 AS A BIOMARKER FOR CANCER PATIENTS AND A TARGET FOR CANCER THERAPY
The invention pertains to biomarkers for identifying a cancer that is likely or not likely to evade the immune system of a subject, thus, is likely or not...
2017/0321284 CLONAL HAEMATOPOIESIS
The present invention relates to clonal expansion of somatic cells in subjects, and acquired selective advantage of cell clones during the lifetime of a...
2017/0321283 METHODS OF DIAGNOSING CANCER AND OF PREDICTING RESPONSE OF CANCER TO DENDROGENIN A TREATMENT
The present invention relates to methods for the diagnosis and the treatment of cancer, in particular breast cancer. In particular, the present invention...
2017/0321282 IMPROVED TREATMENTS OF CANCER RESISTANT TO TAXOIDS
The present invention relates to improved treatments of cancer resistant to a molecule of the taxoid family. It also relates to methods for selecting a patient...
2017/0321281 METHODS AND COMPOSITIONS FOR TREATMENT OF GLIOBLASTOMA
Techniques for treating a subject with M-GBM and recurrent GBM are provided. Example methods include obtaining at least two M-GBM tumor samples from different...
2017/0321280 NANO-PLASMONIC MOLECULAR PROBES FOR PLASMONICS COUPLING INTERFERENCE
Plasmonics-active nanoprobes are provided for detection of target biomolecules including nucleic acids, proteins, and small molecules. The nucleic acids that...
2017/0321279 NON-INVASIVE DETECTION OF FETAL GENETIC TRAITS
Blood plasma of pregnant women contains fetal and (generally >90%) maternal circulatory extracellular DNA. Most of said fetal DNA contains .ltoreq.500 base...
2017/0321278 DETECTION AND TREATMENT OF POLYCYSTIC KIDNEY DISEASE
Compositions useful for examining the PKD1 gene are provided. In addition, methods for detecting mutations of the PKD1 gene, which can be associated with...
2017/0321277 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND MANAGEMENT OF DIABETES AND METABOLIC SYNDROME
Described herein are assays, methods, and devices for diagnosing/prognosing diabetes, metabolic syndrome, pre-diabetic state and/or the early-onset of diabetes...
2017/0321276 METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS
Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.
2017/0321275 Reagent for detecting cross contamination of PDX-model related with human and mouse, the kit comprising the...
The present application relates to a detection kit for genotypes capable of confirming cross contamination that may occur in a banking process of a...
2017/0321274 EPIGENETIC MARKERS OF PLURIPOTENCY
Epigenetic methods for assessing pluripotentcy of a cell population, such as a stem cell culture are provided. For example, pluripotency can be assessed by...
2017/0321273 METHODS AND COMPOSITIONS FOR NUCLEIC ACID AMPLIFICATION
Compositions that are used in nucleic acid amplification in vitro are disclosed, which include a target specific universal (TSU) promoter primer or promoter...
2017/0321272 CHEMICAL SENSING DEVICE
An apparatus with a transducer having a first output signal and arranged to receive an electrical input. The transducer switches the first output signal...
2017/0321271 COMBINATORIAL BARCODE SEQUENCES, AND RELATED SYSTEMS AND METHODS
A kit for use with a nucleic acid sequencing instrument can include a plurality of combinatorial barcodes sequences meeting the following criteria: each of the...
2017/0321270 NONINVASIVE PRENATAL DIAGNOSTIC METHODS
Prenatal genetic testing allows early detection of genetic disease in a fetus. Described herein are methods of detecting the presence or absence of a genetic...
2017/0321269 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES
The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of...
2017/0321267 DESIGN AND SYNTHESIS OF CLEAVABLE FLUORESCENT NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS
This invention provides novel azido linkers for deoxynucleotide analogues having a detectable marker attached thereto.
2017/0321266 ADAPTORS FOR NUCLEIC ACID CONSTRUCTS IN TRANSMEMBRANE SEQUENCING
The invention relates to adaptors for sequencing nucleic acids. The adaptors may be used to generate single stranded constructs of nucleic acid for sequencing...
2017/0321265 POROUS MATRIX COMPRISING NUCLEIC ACID PRIMER-CARBON MATERIAL COMPOSITES AND PCR USING THE SAME
A porous matrix according to the present disclosure, wherein a nucleic acid primer-carbon material composite in which one or more nucleic acid primer of a...
2017/0321264 METHOD FOR DETERMINING A PROPERTY OF A STARTING SAMPLE
A method is provided for determining a property of a starting sample, for example the amount of the nucleic acid (DNA) present therein.
2017/0321263 METHOD OF AMPLIFYING CIRCULAR DNA
The present invention provides a method for easily and exponentially amplifying circular DNA, particularly long chain circular DNA, in a cell-free system....
2017/0321262 Recombinase Polymerase Amplification
This disclosure describes related novel methods for Recombinase-Polymerase Amplification (RPA) of a target DNA that exploit the properties of recombinase and...
2017/0321261 METHOD FOR THE DETECTION OF CIRCULATING TUMOUR CELLS, BOTH CIRCULATING TUMOUR CELLS OF THE EPITHELIAL PHENOTYPE...
The present invention provides an in vitro method of detecting circulating tumour cells, circulating tumour cells of epithelial phenotype and circulating...
2017/0321260 MUTATION IDENTIFICATION METHOD
The present invention relates to a method for identifying the position of a genetic mutation and to the use of said method for simplifying the screening of...
2017/0321259 PROBES FOR IMPROVED MELT DISCRIMINATION AND MULTIPLEXING IN NUCLEIC ACID ASSAYS
Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of cleavable...
2017/0321258 DETECTION OF DRUG RESISTANT MYCOBAC TUBERCULOSIS
This invention relates to nucleic acids, reagents and methods for detecting Rifampicin-resistant Mycobacterium tuberculosis in a sample from a subject. In one...
2017/0321257 BACTERIAL PATHOGEN IDENTIFICATION BY HIGH RESOLUTION MELTING ANALYSIS
Methods and oligonucleotide reagents for identification of bacteria by high resolution melting (HRM) analysis are described. In particular, the invention...
2017/0321256 METHODS FOR DISTINGUISHING INFLAMMATORY BOWEL DISEASES USING MICROBIAL COMMUNITY SIGNATURES
The inventive subject matter relates broadly to novel techniques for identification and comparative analysis of sequence features in metagenomic whole-genome...
2017/0321255 INSTRUMENT FOR CASSETTE FOR SAMPLE PREPARATION
A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel...
2017/0321254 METHODS FOR GENERATING STABILIZED LYOPHILIZED MATERIALS
Lyophilized biological reagents, such as enzymes (e.g., PCR reagents) and antibodies, are provided that include a wax component. Thus, in some aspects, a...
2017/0321253 TARGET SEQUENCE ENRICHMENT
The present invention provides methods, systems, kits, and compositions for magnetically purifying target nucleic acid sequences from a sample using bait...
2017/0321252 CAPSULE ARRAY DEVICES AND METHODS OF USE
This disclosure provides microwell capsule array devices. The microwell capsule array devices are generally capable of performing one or more sample...
2017/0321251 METHODS OF IDENTIFYING MULTIPLE EPITOPES IN CELLS
The invention provides methods, compositions, kits and devices for the detection of target molecules. In some embodiments, the invention allows for multiplexed...
2017/0321250 Methods and Reagents for Reverse-Transcription Polymerase Chain Reaction
The present invention provides a method of amplifying an RNA molecule in a biological sample by reverse transcription PCR (RT-PCR), wherein the RT-PCR is...
2017/0321249 OPTICAL LENS SYSTEM AND METHOD FOR MICROFLUIDIC DEVICES
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one...
2017/0321248 METHODS AND PRODUCTS FOR QUANTIFYING RNA TRANSCRIPT VARIANTS
The present invention relates to the field of transcriptomics and provides a method for the controlled identification and/or quantification of transcript...
2017/0321247 CANCER MARKER AND CANCER DETERMINATION METHOD
The invention relates to a cancer marker, consisting of a portion of or all of the nucleotide sequence represented by SEQ ID NO: 1 in a FOXB2 gene derived from...
2017/0321246 QUANTIFICATION OF NON-REDUCING END GLYCAN RESIDUAL COMPOUNDS FOR DETERMINING THE PRESENCE, IDENTITY, OR...
Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
2017/0321245 Flash and Glow 1,2-Dioxetanes
Compounds having chemiluminescent flash and glow properties. Also disclosed are methods using the compounds to generate light, detect and/or quantify enzymes,...
2017/0321244 SYSTEMS AND METHODS FOR STERILITY TESTING OF RADIONUCLIDE GENERATOR COLUMN ASSEMBLIES
A method includes sterilizing a column assembly including a column having a parent radionuclide contained therein with a sterilizer. The method further...
2017/0321243 IMPROVED METHOD FOR DETERMINATION OF MICROORGANISMS
The present invention relates to determination of the microorganism content in material comprising cellulose within the pulp and paper industry. The material...
2017/0321242 TRANSFORMED CELLS THAT FERMENT PENTOSE SUGARS AND METHODS OF THEIR USE
The present invention relates to host cells transformed with a nucleic acid sequence encoding a eukaryotic xylose isomerase obtainable from an anaerobic...
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