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Patent # Description
2017/0321241 21-Hydroxylation of Steroids
Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the...
2017/0321240 GLYCOSYLATION MUTANTS FOR PRODUCING GALACTOSE-FREE AND FUCOSE-FREE POLYPEPTIDES
We describe a method of reducing batch-to-batch variation or increasing homogeneity between batches in the production of a recombinantly expressed polypeptide....
2017/0321239 CELL-FREE PROTEIN EXPRESSION USING ROLLING CIRCLE AMPLIFICATION PRODUCT
Methods for in vitro transcription and translation from an RCA product are provided. The methods comprise providing a double-stranded RCA product, wherein the...
2017/0321238 Recombinant Production of Steviol Glycosides
Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases...
2017/0321237 Improved Production of Glucose Syrups
The present invention relates to a method of making glucose syrup from liquefied starch, and to compositions useful therein.
2017/0321236 METHOD FOR THE MANUFACTURE OF BIO-PRODUCTS WITH A MODIFIED SUGAR PROFILE
The invention relates to a method for the production of a solid bio-product wherein at least 80% of the original indigestible oligosaccharide (raffmose,...
2017/0321235 TRANSFORMED FUNGUS HAVING ENHANCED ERGOTHIONEINE PRODUCTIVITY AND METHOD FOR PRODUCING ERGOTHIONEINE
The purpose of the present invention is to provide an organism having an ergothioneine productivity that is capable of easily producing ergothioneine within a...
2017/0321234 SYNTHESIS OF LONG-CHAIN POLYUNSATURATED FATTY ACIDS BY RECOMBINANT CELL
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and...
2017/0321233 PROCESSING BIOMASS
Biomass (e.g., plant biomass, animal biomass, microbial, and municipal waste biomass) is processed to produce useful products, such as food products and amino...
2017/0321232 CARBON CAPTURE IN FERMENTATION
The invention relates to a method for producing products by microbial fermentation. The method comprises first converting a feed stream containing methane to a...
2017/0321231 Surfactant-Improved Simultaneous Saccharification and Co-Fermentation Method for Lignocellulose
A surfactant-improved simultaneous saccharification and co-fermentation method for lignocelluloses in which a pretreated lignocellulose substrate is directly...
2017/0321230 Diterpene Synthases and Method for Producing Diterpenoids
Provided herein are diterpene synthases (diTPS) and methods for producing diterpenoids. Also provided herein are nucleic acid sequences encoding diTPS, diTPS...
2017/0321229 Alkenol Dehydratase Variants
Described are alkenol dehydratase variants having improved activity in catalyzing the conversion of prenol into isoprene, methods for the production of...
2017/0321228 Method for Enhancing Microbial Methane Produciton
A process for revitalization of the coal deposit for enhanced microbial gas production by exposing coal deposit to air oxidation. Water is removed from coal...
2017/0321227 Plant Activator Composition
A plant activator composition increases the concentration of terpenes a terpinoids in aromatic plant oils, and hence resulting in an increased concentration of...
2017/0321226 CRISPR ENABLED MULTIPLEXED GENOME ENGINEERING
Described herein are methods and vectors for rational, multiplexed manipulation of chromosomes within open reading frames (e.g., in protein libraries) or any...
2017/0321225 METHODS, SYSTEMS, AND COMPOSITIONS RELATING TO MiRNA-146a
Some embodiments comprise methods, systems, and compositions to promote, improve and/or increase neuronal differentiation, oligodendrocyte differentiation, or...
2017/0321224 Modified Sendai Virus Vaccine and Imaging Vector
The present invention relates to a Sendai virus or recombinant Sendai virus vector. In particular the present invention provides methods, vectors,...
2017/0321223 NUCLEIC ACID SEQUENCES ENCODING TRANSCRIPTION FACTORS REGULATING ALKALOID BIOSYNTHESIS AND THEIR USE IN...
Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway. In one embodiment,...
2017/0321222 YEAST CELLS EXPRESSING TAR DNA-BINDING PROTEIN 43 AND USES THEREFOR
Disclosed are yeast cells expressing TAR DNA-binding protein 43 (TDP-43) and methods of screening yeast cells to identify compounds that prevent or suppress...
2017/0321221 BIOPHARMACEUTICAL PRODUCTION METHOD
The present invention resides in a method for the manufacture of a disulphide-requiring biopharmaceutical having an element of at least tertiary structure...
2017/0321220 PRESENTATION OF BIOACTIVE PROTEINS
The invention provides a fusion protein comprising an antigen binding domain linked to a bacteriophage decoration (Dec) protein along with a polynucleotide...
2017/0321219 OLIGONUCLEOTIDE COMPOSITIONS WITH ENHANCED EFFICIENCY
The oligonucleotide compositions of the present invention make use of combinations of oligonucleotides. In one aspect, the invention features an...
2017/0321218 FACTOR XIA-SPECIFIC APTAMERS
The present disclosure concerns aptamers of formula (I) capable of specifically binding to Factor XIa. The aptamers can be used to prevent, treat or alleviate...
2017/0321217 ANTISENSE OLIGONUCLEOTIDE FOR SPLICING ADJUSTMENT OF MUTANT DOPA DECARBOXYLASE GENE AND USING METHOD THEREOF
This present invention discloses an antisense oligonucleotide for splicing adjustment of mutant dopa decarboxylase gene which is complementary to SEQ ID NO: 1....
2017/0321216 MODULATION OF AGPAT5 EXPRESSION
Provided herein are methods, compounds, and compositions for reducing expression of an AGPAT5 mRNA and protein in an animal. Also provided herein are methods,...
2017/0321215 ALBUMIN PRODUCTION AND CELL PROLIFERATION
The present invention provides short activating RNA molecules which up-regulate albumin production. The present invention also provides methods of...
2017/0321214 DEAD GUIDES FOR CRISPR TRANSCRIPTION FACTORS
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are...
2017/0321213 Compositions and Methods for Inhibiting Expression of Transthyretin
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression...
2017/0321212 SYSTEM FOR ISOLATING DNA MOLECULES
Systems and methods for isolating DNA molecules that can include the steps of: providing a transposon mutant collection, the transposon mutant collection being...
2017/0321211 Whole Genome Mapping by DNA Sequencing With Linked-Paired-End Library
The present invention relates to innovative means of generating sequence-linked DNA fragments and subsequent uses of such linked DNA fragments for de novo...
2017/0321210 METHOD FOR MODIFYING GENOME SEQUENCE TO INTRODUCE SPECIFIC MUTATION TO TARGETED DNA SEQUENCE BY BASE-REMOVAL...
The present invention provides a method of modifying a targeted site of a double stranded DNA, including a step of contacting a complex wherein a nucleic acid...
2017/0321209 METHOD FOR ISOLATING DNA
The present invention provides a method for the isolation of nucleic acid from microbial cells in an environmental sample. The method includes preparing a...
2017/0321208 THERAPEUTIC CELL WASHING, CONCENTRATION, AND SEPARATION UTILIZING ACOUSTOPHORESIS
Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the...
2017/0321207 Device and a Method for Immobilization of Proteins, Enzymes or Cells
Provided herein are a device and a method for preparation of immobilized proteins, enzymes or cells on a carrier to achieve the industrial batch production of...
2017/0321206 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF...
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements...
2017/0321205 UBIQUITIN VARIANT MODULATORS OF SCF E3 LIGASES AND THEIR USES
The invention provides ubiquitin variants that specifically bind to SCF E3 ligases, and use of these variants to modulate the activity of SCF E3 ligases.
2017/0321204 METHODS FOR EXTRACTING AND PURIFYING NON-DENATURED PROTEINS
Materials and methods for extracting and purifying proteins are provided. For example, the materials and methods provided herein can be used for extracting and...
2017/0321203 METHODS FOR EXTRACTING AND PURIFYING NON-DENATURED PROTEINS
Materials and methods for extracting and purifying proteins are provided. For example, the materials and methods provided herein can be used for extracting and...
2017/0321202 PENICILLIN-G ACYLASES
The present invention provides engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions...
2017/0321201 ENZYME-INHIBITOR COMPLEXES
The present invention concerns a method for selectively activating a thermostable hydrolase at a temperature above T1. The present invention provides...
2017/0321200 Polypeptides Having Endoglucanase Activity and Polynucleotides Encoding Same
The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also...
2017/0321199 ALICYCLOBACILLUS VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs,...
2017/0321198 NOVEL CRISPR ENZYMES AND SYSTEMS
The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or...
2017/0321197 Lipase Variants and Polynucleotides Encoding Same
The present invention relates to a variant of a parent lipase, which parent lipase has the amino acid sequence of SEQ ID NO: 2, wherein the variant has lipase...
2017/0321196 ANALYTICAL AND DIAGNOSTIC METHODS UTILIZING SHIGELLA FLEXNERI APYRASE
A method, comprising the steps of providing a sample containing contaminating nucleoside diphosphates and/or nucleoside triphosphates, such as ATP and/or ATP...
2017/0321195 POLYMERASES
Presented herein are methods and compositions for thermostable DNA polymerases that may be used to improve the PCR process and to improve the results obtained...
2017/0321194 MODULATION OF LIPID METABOLISM FOR PROTEIN PRODUCTION
The present disclosure features methods and compositions for modulating lipid metabolism to achieve improved production and quality of recombinant products,...
2017/0321193 VARIANT FORMS OF URATE OXIDASE AND USE THEREOF
Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including...
2017/0321192 Recombinant RNA Viruses and Uses Thereof
Described herein are modified RNA virus gene segments and nucleic acids encoding modified RNA virus gene segments. Also described herein are recombinant RNA...
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