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Patent # Description
2017/0326265 APPARATUS AND METHOD FOR DETECTING MOISTURE IN A VACUUM CHAMBER
A method of operating a sterilization system having a vacuum chamber for sterilizing instruments, the chamber connected to a reservoir of sterilant by a valve...
2017/0326264 COMPACT AIR CLEANER USING UV LED AND PHOTOCATALYTIC FILTER
Disclosed herein is an air cleaner which performs dust collection and sterilization as well as deodorization while having a small size enough to be fitted into...
2017/0326263 SCENTED ATTACHMENT FOR CONTAINERS
Aspects of the disclosure include an attachment for providing a scent to a container. The scented attachment may be configured for being associated with a...
2017/0326262 ULTRAVIOLET AND MISTING DISINFECTING UNIT
A disinfecting unit and method of operating the same includes a cabinet having a vertical axis, a first lamp coupled to the cabinet directing light in a...
2017/0326261 BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF
Disclosed are chelates resulting from the complexation of bifunctional do2pa derivatives ligands of formula (I), wherein the substituents R.sup.1, R.sup.1',...
2017/0326260 ANTIBODIES THAT BIND ACTIVATABLE ANTIBODIES AND METHODS OF USE THEREOF
The invention relates generally to antibodies and antigen-binding fragments thereof that bind activatable antibodies and/or conjugated activatable antibodies...
2017/0326259 STABILIZED RADIOLABELED ANTI-CD45 IMMUNOGLOBULIN COMPOSITIONS
Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The...
2017/0326258 CONTRAST AGENTS BASED ON LONG-LIVED NUCLEAR SINGLET STATES AND RELATED METHODS
Methods are described for preparing magnetic resonance imaging (MRI) and/or magnetic resonance spectroscopy contrast agents where the contrast agents are...
2017/0326257 SATIATION PEPTIDES FOR WEIGHT LOSS AND ALTERED TASTE SENSITIVITY
The present application provides methods and compositions for AAV-mediated delivery of PYY and Glucagon-like Peptide 1 or an analog thereof (e.g., Exendin-4)...
2017/0326256 RECOMBINANT PROMOTERS AND VECTORS FOR PROTEIN EXPRESSION IN LIVER AND USE THEREOF
Disclosed herein are recombinant viral vectors comprising a liver specific promotor in operable combination with a heterologous nucleic acid sequence encoding...
2017/0326255 SUCROSE ESTER BASED CATIONIC GENE VECTOR AND PREPARATION METHOD THEREOF
The invention provides a class of sucrose ester based cationic lipids and preparation method thereof. The vector prepared using the cationic lipid can be used...
2017/0326254 Efficient delivery of therapeutic molecules in vitro and in vivo
A chimeric molecule of one or more proteins or peptides fused, complexed or linked to one or more anionic molecules. Efficient in vitro and in vivo delivery is...
2017/0326253 PH-SENSITIVE PEPTIDES AND THEIR NANOPARTICLES FOR DRUG DELIVERY
A new nanoscale carrier made by one or more pH-sensitive peptides is provided for delivery of a biologically active substance. The peptides are composed of...
2017/0326252 Nanoparticles for Delivery of Agents to Glioblastoma Tumors
The present invention is, in general, directed to nanoparticles for the delivery of agents to glioblastoma tumors. More particularly, the present invention...
2017/0326251 METHOD OF SYNTHESIZING ANTIBODY DRUG CONJUGATES USING AFFINITY RESINS
Disclosed is a solid phase method of synthesizing biomolecule-drug-conjugates. In particular, this invention relates to a solid phase method of synthesizing...
2017/0326250 CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF
Disclosed herein are immunoconjugates comprising an inhibitor of Eg5 linked to an antigen binding moiety such as an antibody, that are useful for treating cell...
2017/0326249 ANTIBODY-DRUG CONJUGATE OF AN ANTI-GLYPICAN-3 ANTIBODY AND A TUBULYSIN ANALOG, PREPARATION AND USES
An antibody-drug conjugate having a structure represented by formula (I) ##STR00001## wherein m is 1, 2, 3, or 4 and Ab is an anti-glypican-3 antibody having ...
2017/0326248 ANTI-CD22 ANTIBODIES AND IMMUNOCONJUGATES
The invention provides anti-CD22 antibodies and immunoconjugates and methods of using the same.
2017/0326247 ANTIBODY-DRUG CONJUGATES OF TUBULYSIN ANALOGS WITH ENHANCED STABILITY
The drug component of an antibody-drug conjugate having a structure according to formula (II), where Ab, m, n, R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5...
2017/0326246 CONJUGATED MOLECULES COMPRISING A PEPTIDE DERIVED FROM THE CD4 RECEPTOR COUPLED TO AN ANIONIC POLYPEPTIDE FOR...
This invention relates to a conjugated molecule comprising a peptide derived from the CD4 receptor coupled to an organic molecule by means of a linker as well...
2017/0326245 Methods and Compositions Related To Annexin 1-Binding Compounds
Compositions and methods related to annexin 1-binding compounds. Also compositions comprising a moiety and a peptide comprising an amino acid sequence that can...
2017/0326244 BIOTIN COMPLEXES FOR TREATMENT AND DIAGNOSIS OF ALZHEIMER'S DISEASE
Described herein are compositions and methods for treating or imaging Alzheimer's disease (AD). The compositions comprise a biotin moiety and a siRNA moiety,...
2017/0326243 METHODS AND SYSTEMS FOR TREATING OR PREVENTING CANCER
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of cancer or other conditions. In some cases,...
2017/0326242 FILMOGENIC COMPOSITIONS FOR TOPICAL ANAESTHETIC BIOADHESIVES - TABS, FOR CONTROLLED RELEASE OF ACTIVE...
Filmogenic compositions are described for topical anaesthetic bioadhesives (TABs) comprising a) a xanthan biopolymer matrix selected from Xanthomonas species...
2017/0326241 WOUND HEALING USING TOPICAL SYSTEMS AND METHODS
The present invention generally relates to compositions and methods for topical or transdermal delivery and treatment of wounds and/or promoting wound healing....
2017/0326240 STABILIZED EFINACONAZOLE COMPOSITIONS
The present invention provides compositions containing efinaconazole, butylated hydroxytoluene, a salt of ethylenediaminetetraacetic acid, and optional citric...
2017/0326239 ARTIFICIAL BACTERIOPHAGE BASED ON CARBON NANOSTRUCTURES FOR SUPPLYING MEDICAMENTS
The invention relates to an artificial bacteriophage for supplying medicaments, nutrients, proteins, DNA/RNA or other type of molecules to bacteria and/or...
2017/0326238 CROSSLINKING OF CD22 BY EPRATUZUMAB TRIGGERS BCR SIGNALING AND CASPASE-DEPENDENT APOPTOSIS IN HEMATOPOIETIC...
Extensive crosslinking of CD22 by plate-immobilized epratuzumab induced intracellular changes in Daudi cells similar to ligating B-cell antigen receptor (BCR)...
2017/0326237 COSMETIC AND PHARMACEUTICAL AGENTS FOR TREATING WOUNDS AND/OR HEMORRHAGING OF THE SKIN, MUCOUS MEMBRANES OR THE...
The invention relates to an agent, in particular a cosmetic and/or pharmaceutical agent, containing an active composition and optionally an adhesion...
2017/0326235 COMBINATION TUMOR TREATMENT WITH DRUG-LOADED, BISPECIFIC LIGAND-TARGETED MINICELLS AND INTERFERON-GAMMA
Compositions and methods are provided for cancer treatments. The methodology entails, for instance, administering to a cancer patient a first composition...
2017/0326234 COMBINATION THERAPIES
The present invention provides combination therapy methods of treating a proliferative disease (such as cancer) comprising a first therapy comprising...
2017/0326233 CONJUGATES INCLUDING AN ANTIBODY MOIETY, A POLYPEPTIDE THAT TRAVERSES THE BLOOD-BRAIN BARRIER, AND A CYTOTOXIN
The present invention relates to antibody-polypeptide-cytotoxin conjugates and methods of making, packaging, and using the conjugates. The polypeptide can be a...
2017/0326232 INTRATUMORAL ADMINISTRATION OF PARTICLES CONTAINING A TOLL-LIKE RECEPTOR 9 AGONIST AND A TUMOR ANTIGEN FOR...
The present disclosure relates to methods for treating cancer by intratumoral delivery of particles containing a Toll-like receptor 9 agonist (TLR9) and a...
2017/0326231 EPITOPE OF HEPATITIS B VIRUS SURFACE ANTIGEN AND BINDING MOLECULE SPECIFICALLY BINDING TO SAME FOR NEUTRALIZING...
The present invention relates to an epitope specific to hepatitis B virus surface antigen and a binding molecule binding to the same for neutralizing hepatitis...
2017/0326230 STABLE LIQUID VACCINIA VIRUS FORMULATIONS
The present invention relates to liquid formulations of poxvirus, in particular vaccinia virus, stable during storage. Such stable liquid formulations comprise...
2017/0326229 SWARM IMMUNIZATION WITH 54 ENVELOPES FROM CH505
In certain aspects the invention provides HIV-1 immunogens, including envelopes (CH505) and selections therefrom, and methods for swami immunizations using...
2017/0326228 RECOMBINANT MODIFIED VACCINIA VIRUS ANKARA (MVA) RESPIRATORY SYNCYTIAL VIRUS (RSV) VACCINE
Provided herein are recombinant modified vaccinia virus Ankara (MVA) strains as improved vaccines against infection with Respiratory Syncytial Virus (RSV...
2017/0326227 INFLUENZA VIRUS REASSORTMENT
New influenza donor strains for the production of reassortant influenza A viruses are provided.
2017/0326226 COMPOSITION COMPRISING ANTIGENS AND A MUCOSAL ADJUVANT AND A METHOD FOR USING
The majority of the mortality observed in young pigs occurs between three and five weeks post-weaning for S. suis infections and between four and six weeks...
2017/0326225 EBOLAVIRUS AND MARBURGVIRUS VACCINES
The present invention relates to an mRNA sequence, comprising a coding region, encoding at least one antigenic peptide or protein derived from the glycoprotein...
2017/0326224 HUMAN PAPILLOMA VIRUS CONSTRUCTS
Embodiments of the present invention provide compositions and methods for recombinantly generating tagless constructs of proteins or peptides. In certain...
2017/0326223 NOVEL SURFACE EXPOSED HAEMOPHILUS INFLUENZAE PROTEIN (PROTEIN E; pE)
The present invention relates to a surface exposed protein (protein E; pE), a virulence factor, which can be detected in Haemophilus influenzae, having an...
2017/0326222 NON-LIPIDATED VARIANTS OF NEISSERIA MENINGITIDIS ORF2086 ANTIGENS
The present invention relates to compositions including an isolated non-pyruvylated non-lipidated ORF2086 polypeptide, and methods thereof. In an exemplary...
2017/0326221 Detoxification method for lipopolysaccharide (LPS) or lipid A of Gram-negative bacteria
The invention relates to a method of detoxifying a lipopolysaccharide (LPS) or a lipid A from a Gram-negative bacterium, which comprises mixing the LPS or the...
2017/0326220 MENINGITIS B VACCINE
Compositions, including vaccine compositions, are provided comprising outer membrane vesicles (OMVs) from N. meningitidis B (MenB). Also provided are methods...
2017/0326219 Vaccine for Falciparum Malaria
The invention provides compositions and methods for preventing or reducing the severity of malaria.
2017/0326218 PEPTIDE MIXTURE
There is disclosed a peptide mixture suitable for eliciting an immune response. It comprises a first and a second peptide, each corresponding to a fragment of...
2017/0326217 NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS INCLUDING NEURONAL AND BRAIN TUMORS
A method of treating a patient who has brain cancer includes administering to said patient a composition containing a population of activated T cells that...
2017/0326216 Immunotherapy against melanoma and other cancers
A method of treating a patient who has melanoma includes administering to said patient a composition containing a population of activated T cells that...
2017/0326215 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST PROSTATE CANCER AND OTHER CANCERS
A method of treating a patient who has liver cancer (HCC), breast cancer (BRCA), melanoma, and/or uterine cancer includes administering to said patient a...
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