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Patent # Description
2017/0333441 COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS
The present invention relates to methods for treating a microbial infection comprising treating the infected tissue with a composition comprising a quinolone...
2017/0333440 TRICYCLIC LACTAMS FOR USE IN HSPC-SPARING TREATMENTS FOR RB-POSITIVE ABNORMAL CELLULAR PROLIFERATION
This invention is in the area of tricyclic lactam compounds for and methods of treating selected Rb-positive cancers and other Rb-positive abnormal cellular...
2017/0333439 APILIMOD FOR USE IN THE TREATMENT OF MELANOMA
The present invention relates to methods for treating melanoma with apilimod and related compositions and methods.
2017/0333438 CRYSTALLINE FORMS OF (2R,5S,13AR)-8-HYDROXY-7,9-DIOXO-N-(2,4,6-TRIFLUOROBENZYL)-2,3,4,5,7,9,13- ...
The present invention relates to crystalline forms and co-crystals of (2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13- ...
2017/0333437 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES
The present invention provides compounds of Formula A: ##STR00001## or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the...
2017/0333436 HCK AS A THERAPEUTIC TARGET IN MYD88 MUTATED DISEASES
Methods of treatment of conditions or diseases associated with myeloid differentiation primary response (MYD88) protein using a selective HCK inhibitor are...
2017/0333435 SUBSTITUTED IMIDAZO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
The invention provides substituted imidazo.left brkt-top.1,5-a.right brkt-bot.pyrimidines and related organic compounds, compositions containing such...
2017/0333434 ADMINISTRATION OF UBIQUITIN-ACTIVATING ENZYME INHIBITOR AND RADIATION
Disclosed are methods for the treatment of cancer in patients in need of such treatment. The methods comprise administering to such a patient an ...
2017/0333433 QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF
The invention relates to quinazoline derivatives substituted by aniline which are represented by the below formula (I), pharmaceutical acceptable salts and...
2017/0333432 Detection and treatment of excessive hair shedding
The present invention relates to a method of treating or preventing hair loss or excessive hair shedding in a subject by administering to a subject an oral...
2017/0333431 Combined Hair Loss Inhibition Treatment
A hair growth formulation includes minoxidil and foeniculum vulgare, atriplex nummularia extract, or a combination of foeniculum vulgare and atriplex...
2017/0333430 COMBINATION THERAPY WITH GLUTAMINASE INHIBITORS
The invention relates to methods of treating cancer, myeloproliferative diseases, or immunological or neurological diseases with a combination of a glutaminase...
2017/0333429 1,3,4-Thiadiazole Compounds and Their Use in Treating Cancer
A compound of Formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof, is described. Q can be pyridazin-3-yl, 6-fluoropyridazin-3-yl; R.sup.1...
2017/0333428 Methods for Treating HCV
The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as...
2017/0333427 MULTI-DRUG THERAPIES FOR TUBERCULOSIS TREATMENT
The present invention is directed to methods of treating tuberculosis by providing a pharmaceutically effective amount of a combination of drug compounds.
2017/0333426 1,2,4-Triazolo [4,3-A] Pyridine Derivatives And Their Use For The Treatment Of Prevention Of Neurological And...
The present invention relates to methods of treating various central nervous system disorders using novel triazolo[4,3-a]pyridine derivatives of Formula (I) ...
2017/0333425 TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM
A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic...
2017/0333424 Amorphous Vortioxetine Hydrobromide
The present invention relates to a pharmaceutical composition comprising amorphous vortioxetine hydrobromide, a process for the preparation thereof, use...
2017/0333423 PHARMACEUTICAL COMPOSITIONS COMPRISING DEXTROMETHORPHAN AND QUINIDINE FOR THE TREATMENT OF AGITATION IN DEMENTIA
This disclosure provides pharmaceutical compositions comprising dextromethorphan in combination with quinidine, and methods for treating agitation and/or...
2017/0333422 Morphinan Derivatives for the Treatment of Drug Overdose
The instant application relates to morphinan derivatives of Formula I with sustained effectiveness in treating drug toxicity and overdose: ##STR00001##
2017/0333421 Population Pharmacokinetics of Liposomal Irinotecan
Nal-IRI is a liposomal formulation of irinotecan with a longer half-life (t.sub.1/2), higher plasma total irinotecan (tIRI), and lower SN-38 maximum...
2017/0333420 TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD
Disclosed is a method for treating an ocular inflammatory disease (OID), e.g., uveitis or conjunctivitis, comprising periodic administration of a ...
2017/0333419 NOVEL ANTI-INFLAMMATORY AGENTS
Disclosed are methods of regulating interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1) and methods of treating and/or preventing...
2017/0333418 TREATMENT OF MULTIPLE SCLEROSIS WITH COMBINATION OF LAQUINIMOD AND FINGOLIMOD
This invention provides a method of treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering...
2017/0333417 SALTS AND COMPOSITIONS USEFUL FOR TREATING DISEASE
The invention provides a combination or salt of lipoic acid and a compound of formula (I): The combinations and salts are useful for treating diabetes.
2017/0333416 METHODS AND DEVICES FOR THE TREATMENT OF OCULAR DISEASES IN HUMAN SUBJECTS
Methods and devices are provided for targeted non-surgical administration of a drug formulation to the suprachoroidal space (SCS) of the eye of a human subject...
2017/0333415 Method of Treating Substance Addictions
A pharmaceutical composition containing isomyosmine or a pharmaceutically acceptable salt thereof is administered to an individual in need thereof for treating...
2017/0333414 NOVEL OXAZOLIDINONE DERIVATIVES
The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an...
2017/0333413 ENHANCEMENT OF TUMOR RESPONSE TO CHEMOTHERAPY BY ACTIVATION OF THE ASMASE/CERAMIDE PATHWAY THROUGH TIMED...
Disclosed is a method for enhancing tumor response to chemotherapy, the method comprising administering a short-acting anti-angiogenic agent (AAA) capable of...
2017/0333412 METHOD FOR TREATING LYMPHEDEMA
The disclosure relates to the field of lymphedema therapy, more specifically, to a new pharmacological strategy to rescue the failed lymph pump system that can...
2017/0333411 PIRFENIDONE TREATMENT FOR PATIENTS WITH ATYPICAL LIVER FUNCTION
Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone...
2017/0333410 Dermal Pharmaceutical Compositions of 1-Methyl-2',6'-Pipecoloxylidide and Method of Use
The present invention is directed to therapeutic pharmaceutical compositions of 1-Methyl-2', 6'-pipecoloxylidide or it pharmaceutically acceptable salts for...
2017/0333409 1H-PYRAZOLO[3,4-B]PYRIDINES AND THERAPEUTIC USES THEREOF
Provided herein are compounds according to Formulas (I) or (II) and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in...
2017/0333408 APILIMOD FOR USE IN THE TREATMENT OF RENAL CANCER
The present disclosure relates to methods for treating renal cancer with apilimod and related compositions and methods.
2017/0333407 METHOD FOR TREATING UNDERACTIVE BLADDER SYNDROME
Disclosed are nonlimiting embodiments comprising novel methods for treating underactive bladder in a subject, including administering an effective amount of a...
2017/0333406 THERAPEUTIC COMPOUNDS AND USES THEREOF
The present invention relates to compounds of formula (I) or formula (II): ##STR00001## and to salts thereof, wherein R.sup.1-R.sup.4 of formula (I) and ...
2017/0333405 CONVERGENT AND ENANTIOSELECTIVE TOTAL SYNTHESIS OF COMMUNESIN ANALOGS
A highly convergent biomimetic synthesis of a complex polycyclic scaffold has been successfully implemented. From these efforts, compounds having a structure...
2017/0333404 IMPROVED FORMULATIONS OF VEMURAFENIB AND METHODS OF MAKING THE SAME
The disclosure provides for improved pharmaceutical compositions containing vemurafenib and methods of manufacturing the same. In particular, the compositions...
2017/0333403 THERAPEUTIC AGENTS FOR INNER EAR HEARING IMPAIRMENT
An object of the present invention is to provide novel apoptosis inhibitors and therapeutic agents for inner ear hearing impairment. As a pharmaceutical agent...
2017/0333402 MEDICINE FOR IMPROVING STATE OF PREGNANCY, AND USE THEREOF
A medicine for improving the state of pregnancy, which comprises a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof as...
2017/0333401 ITE FOR CANCER INTERVENTION AND ERADICATION
A method of cancer intervention or eradication by administering an effective amount of an endogenous ligand for the aryl hydrocarbon (Ah) receptor (AhR) named...
2017/0333400 TOPICAL FORMULATIONS OF BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
The present invention relates to topical formulations of biaryl heterocyclic compounds and methods of use thereof for treating acne and other skin infections...
2017/0333399 Isoxazole Derivatives as FXR Agonists and Methods of Use Thereof
The present invention provides compounds of Formula I: ##STR00001## and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these...
2017/0333398 HETEROCYCLIC DERIVATIVE HAVING AMPK-ACTIVATING ACTIVITY
A compound represented by formula: ##STR00001## or its pharmaceutically acceptable salt, wherein L is NR.sup.2R.sup.3, SR.sup.7, SO.sub.2R.sup.8, substituted or...
2017/0333397 PARASITICIDAL COMPOSITIONS COMPRISING FIPRONIL AT HIGH CONCENTRATIONS
The invention provides for spot-on formulations comprising fipronil in a high concentration for the treatment or prophylaxis of parasites of mammals and birds,...
2017/0333396 COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA
The invention provides preparations, formulations, kits and other products of manufacture (e.g., blister packs) comprising combinations of beneficial...
2017/0333395 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of...
2017/0333394 VAGINAL DELIVERY SYSTEMS CONTAINING SELECTIVE ESTROGEN RECEPTOR MODULATOR (SERM) AND USES THEREOF
The present disclosure provides pharmaceutical compositions that include one or more selective estrogen receptor modulator(s) (SERM(s), e.g., Lasofoxifene) and...
2017/0333393 INJECTABLE ANTIOXIDANT FORMULATION FOR INTRAVENOUS USE OF SODIUM ASCORBATE IN HIGH DOSAGE, N-ACETYL CYSTEINE,...
The invention refers to an injectable antioxidant formulation for intravenous use comprising sodium ascorbate in high dosage as a first antioxidant agent,...
2017/0333392 VITAMIN C AND VITAMIN K COMPOUND FOR TREATING PANCREATIC CANCER
Provided herein is a method of treating, preventing, or alleviating one or more symptoms of pancreatic cancer in a subject, comprising administering to the...
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