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Patent # Description
2017/0340740 LONG-ACTING POLYMERIC DELIVERY SYSTEMS COMPRISING OLANZAPINE AND A 5-HT3 RECEPTOR ANTAGONIST
Compositions comprised of olanzapine and a 5-HT3 receptor antagonist and a polyorthoester polymer are provided to provide extended release of the active...
2017/0340739 PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular...
2017/0340738 STABLE ACIDIC INSULIN FORMULATIONS
While the present invention is described herein with reference to illustrated embodiments, it should be understood that the invention is not limited hereto....
2017/0340737 INTERLEUKIN -13 BINDING PROTEINS
The present invention encompasses IL-13 binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized...
2017/0340736 PHOTOACTIVATABLE CAGED TAMOXIFEN AND TAMOXIFEN DERIVATIVE MOLECULES AND METHODS OF USE THEREOF
Provided herein are compositions containing photoactivatable caged tamoxifen and tamoxifen derivative molecules. Also provided are kits containing one of these...
2017/0340735 Anti-TIGIT Antigen-Binding Proteins and Methods of Use Thereof
Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also...
2017/0340734 HUMAN MONOCLONAL ANTIBODIES AGAINST AXL
The present disclosure provides human monoclonal antibodies and antibody-drug conjugates against AXL and their use for the treatment of cancer.
2017/0340733 COMBINATION THERAPIES
Combination therapies are disclosed. The combination therapies can be used to treat or prevent cancerous conditions and/or disorders.
2017/0340732 POLYMERIC IgA-TYPE RECOMBINANT ANTIBODY AND USE THEREOF
Provided are: a polymeric IgA-type recombinant antibody; a medicine containing this polymeric IgA-type recombinant antibody as an active ingredient; a method...
2017/0340731 NON-SPECIFIC DELAYED-TYPE HYPERSENSITIVITY RESPONSE TO TREAT HERPES SIMPLEX VIRUS INFECTION
A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type...
2017/0340730 CONTRUCTS FOR ENHANCING IMMUNE RESPONSES
Chimeric protein constructs including a herpesvirus glycoprotein D (gD) and a heterologous polypeptide that interact with herpes virus entry mediator (HVEM)...
2017/0340729 COMPOSITION COMPRISING PEDV ANTIGENS AND METHODS FOR MAKING AND USING THE COMPOSITION
Disclosed herein are embodiments of an immunogenic composition for porcine epidemic diarrhea virus, and a method for making the immunogenic composition. Also...
2017/0340728 Human Antibodies to Middle East Respiratory Syndrome - Coronavirus Spike Protein
The present invention provides monoclonal antibodies that bind to the Middle East Respiratory Syndrome--Coronavirus (MERS-CoV) spike protein, and methods of...
2017/0340727 A Rabies Composition Comprising Pika Adjuvant
The present disclosure provides a rabies composition comprising IPRV and PIKA adjuvant, and the pharmaceutical use thereof. The present disclosure also...
2017/0340726 GENE-MODIFIED MEASLES VIRUS FOR TUMOR TREATMENT USE
It is an object of the present invention to provide a medicament or a pharmaceutical composition, which is effective for the treatment of various cancers. ...
2017/0340725 COMBINATION PIV3/HMPV RNA VACCINES
The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines and combination vaccines, as well as methods of using the vaccines and compositions...
2017/0340724 ZIKA VIRUS RNA VACCINES
The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines...
2017/0340723 Process for Ready-to-Use PCV2/M.HYO Combination Vaccine
The present invention describes a process for the preparation of an antigen composition, which antigen composition can be used to prepare a ready-to-use...
2017/0340722 Novel immunization agents and methods of use
The present invention relates to a vaccine composition comprising an effective amount of a replication-competent controlled recombinant virus. Further...
2017/0340721 METHODS AND COMPOSITIONS FOR ENHANCING IMMUNE RESPONSES
Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is...
2017/0340720 COMPOSITIONS FOR IMMUNISING AGAINST STAPHYLOCOCCUS AUREUS
An effective Staphylococcus aureus vaccine may require several antigenic components, and so various combinations of S. aureus antigens are identified for use...
2017/0340718 NOVEL POLYSACCHARIDE AND USES THEREOF
Provided herein is a novel E. coli O polysaccharide, O25B. Also provided herein are prokaryotic host cells containing enzymes (e.g., glycosyltransferases) used...
2017/0340717 MSI-SPECIFIC FRAMESHIFT PEPTIDES (FSP) FOR PREVENTION AND TREATMENT OF CANCER
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific...
2017/0340716 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ASTHMA
The present invention provides compounds and methods for treating or preventing pulmonary diseases include COPD and asthma. In particular, the present...
2017/0340715 Materials and Methods Useful For Treating Glioblastoma
The present invention provides compositions and methods useful for treating cancers such as glioblastoma. SapC-DOPS was found to be synergistically effective...
2017/0340714 Compositions for Treating Pathological Calcification Conditions, and Methods Using Same
The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological...
2017/0340713 Compositions for Treating Pathological Calcification Conditions, and Methods Using Same
The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological...
2017/0340712 CAMKK1 AS A NOVEL REGENERATIVE THERAPEUTIC
Disclosed herein are methods of treating an ischemic or inflammatory condition in an organ or tissue of a patient comprising inducing an increase of the level...
2017/0340711 Articular Cartilage Mimetics
A scaffold for promoting cartilage formation is provided that includes a crosslinked electrospun fiber, wherein the crosslinked electrospun fiber consists...
2017/0340710 USE OF HEPCIDIN AS A REGULATOR OF IRON HOMEOSTASIS
The invention concerns the use of hepcidin for the diagnosis and therapy of disorders of iron homeostasis. Hepcidin can be used in the treatment of disorders...
2017/0340709 METHODS OF TREATMENT USING STEM CELL MOBILIZERS
The present invention relates to the field of stem cells. In one aspect, the present invention provides methods of treating a subject with acute liver injury...
2017/0340708 PROTEINACEOUS HETERODIMER AND USE THEREOF
The present disclosure provides proteinaceous heterodimers, pharmaceutical compositions, medicaments and/or kits comprising the proteinaceous heterodimers,...
2017/0340707 System and Method for Multiphasic Release of Growth Factors
A system for multiphasic delivery of at least one growth factor at a treatment site comprises a delivery vehicle for releasing at least one growth factor in an...
2017/0340706 LOCALLY RELEASED GROWTH FACTORS TO MEDIATE MOTOR RECOVERY AFTER STROKE
Methods of improving recovery of a mammal after an ischemic event (e.g., stroke) are provided. In various embodiments the methods involve administering a...
2017/0340705 Cell
The present invention provides a cell which co-expresses a first chimeric antigen receptor (CAR) and second CAR at the cell surface, each CAR comprising an...
2017/0340704 Cell
The present invention provides a cell which co-expresses a first chimeric antigen receptor (CAR) and second CAR at the cell surface, each CAR comprising an...
2017/0340703 TEAR LIPOCALIN MUTEINS BINDING IL-4 R ALPHA
The present invention relates to novel muteins derived from human tear lipocalin, which bind to IL 4 receptor alpha. The sequences of the muteins comprise...
2017/0340702 METHODS FOR DIAGNOSING AND TREATING SYSTEMIC LUPUS ERYTHEMATOSUS
Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as...
2017/0340701 CELL-PERMEABLE PEPTIDE SYSTEM FOR TREATING DISEASES CAUSED BY GLUTAMATE EXCITOTOXICITY
Peptide system including at least one peptide blocking the presynaptic release of glutamate. The peptide has the sequence SEQ ID NO 5: ...
2017/0340700 USE OF AN ANTIMICROBIAL PEPTIDE TP4 IN TREATING A CANCER
The preset invention relates to a new approach for treating a cancer, particularly a malignant tumor, a multidrug-resistant (MDR) cancer, a recurrent cancer or...
2017/0340699 Adenovirus AD36 E4ORF1 Protein For Prevention and Treatment of Non-Alcoholic Fatty Liver Disease
This invention generally relates to methods for treating or preventing the symptoms of non-alcoholic fatty liver disease, methods for reducing excessive fat...
2017/0340698 CYCLIC PEPTIDE SPECIFICALLY BINDING TO APOPTOTIC CELLS AND USE THEREOF
Provided is a cyclic peptide (cyclo [Cys-Gln-Arg-Pro-Pro-Arg-Cys] peptide) comprised of the amino acid sequence of SEQ ID NO: 2; and a composition for...
2017/0340697 SELECTIVE NOX-1 INHIBITOR PEPTIDES AND USES THEREOF
The present invention relates to novel peptides, compositions and methods for the prevention and/or treatment of pathological conditions and diseases...
2017/0340696 CHEMOTHERAPEUTIC COMBINATIONS OF CATIONIC ANTIMICROBIAL PEPTIDES AND CHEMOTHERAPEUTICS
The present invention provides a compound, preferably a peptide, having the following characteristics: a) consisting of 9 amino acids in a linear arrangement;...
2017/0340695 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY
The disclosure relates to methods for treating a subject suffering from hyperalgesia caused by drug-induced neuropathy by administering to the subject an...
2017/0340694 COMPOSITION FOR PROMOTING METALLOTHIONEIN PRODUCTION
The present disclosure relates to a composition to aid in heavy metal detox. Metallothioneins (MT) are a family of cysteine-rich enzymes in the body that help...
2017/0340693 DISLODGEMENT AND RELEASE OF HSC USING ALPHA 9 INTEGRIN ANTAGONIST AND CXCR4 ANTAGONIST
Haematopoietic stem cell mobilization is a process whereby haematopoietic stem cells are stimulated out of the bone marrow space. Before HSC can mobilize, they...
2017/0340692 COMPOSITION FOR LYMPH DRAINAGE
The present invention relates to a mixture of active ingredients consisting of Taraxacum officinalis, Fagopyrum esculentum, Ruscus aculeatus, Solidago...
2017/0340691 An Antimicrobial Composition
The present invention provides an antimicrobial composition comprising at least one garlic extract and one or more of a bioflavonoid and/or an organic acid as...
2017/0340690 METHOD FOR IMPROVING INTESTINAL HEALTH USING EXTRACTS OF CODONOPSIS LANCEOLATA
Disclosed is a method for improving intestinal microflora, which includes administering an extract of Codonopsis lanceolata of an amount effective for...
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