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Patent # Description
2017/0340639 PHARMACEUTICAL COMPOSITION OF PEMETREXED
The present invention relates to pharmaceutical composition comprising pemetrexed, a ready to use injection comprising pemetrexed. Liquid composition of...
2017/0340638 STABLE PHARMACEUTICAL COMPOSITION COMPRISING PEMETREXED OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
Provided is a composition of a ready-to-use injectable solution comprising pemetrexed or pharmaceutically acceptable salts thereof, containing pemetrexed;...
2017/0340636 COMPOSITIONS AND METHODS FOR INHIBITION OF AUTOPHAGY
The present invention concerns compounds and their use to treat cell proliferative disorders including tumor growth and metastasis. Compounds of the present...
2017/0340635 COMBINATION OF A 6-OXO-1,6-DIHYDRO-PYRIDAZINE DERIVATIVE HAVING ANTI-CANCER ACTIVITY WITH A QUINAZOLINE DERIVATIVE
A pharmaceutical composition of 3-(1-{3-[5-(1-Methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo- -1,6-dihydro-pyridazin-3-yl)-benzonitrile or a...
2017/0340634 Trk-INHIBITING COMPOUND
The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for...
2017/0340633 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA
Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3K.delta.) activity, and methods of treating diseases, such as disorders of immunity and...
2017/0340632 Bromocriptine Formulations
The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The...
2017/0340631 BTK INHIBITORS
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts or...
2017/0340630 BENZENESULFONAMIDE DERIVATIVES OF QUINOXALINE, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN METHODS...
Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of using these chemical entities, e.g., for treatment of cancer are...
2017/0340629 MASITINIB COMBINATION FOR USE IN TREATING BREAST CANCER
Disclosed is a method for treating breast cancer in a subject in need thereof, including administering to the subject a therapeutically effective amount of a...
2017/0340628 PROTEIN PHOSPHATASE 2A INHIBITORS FOR TREATING MYELODYSPLASTIC SYNDROMES
Disclosed are methods for treating a myelodysplastic syndrome (MDS) in a subject that involves administering to the subject a therapeutically effective amount...
2017/0340627 PHARMACEUTICAL COMPOSITIONS
Pharmaceutical compositions are provided which comprise effective amounts of an analgesic to treat a subject, including to reduce or eliminate an adverse...
2017/0340626 OXYCODONE FORMULATIONS
The invention is directed to sustained release formulations containing oxycodone or a pharmaceutically acceptable salt thereof which provide a mean...
2017/0340625 COMPOSITION AND METHOD FOR TREATING SKIN CONDITIONS
Compositions and methods for treatment of conditions affecting skin and/or mucosal surfaces of a subject that make use of an imidazoquinoline compound and a...
2017/0340624 Liposomes Useful for Drug Delivery
The present invention provides liposome compositions containing substituted ammonium and/or polyanion, and optionally with a desired therapeutic or imaging...
2017/0340623 COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID...
The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart...
2017/0340622 METHOD OF DETECTING CANCER STEM CELL, METHOD OFSCREENING CANCER STEM CELL, AND METHOD OF INHIBITING CANCERSTEM CELL
An object of the present invention is to provide a cancer cell inhibitory drug, particularly a cancer stem-cell inhibitory drug, or a cancer stem-cell...
2017/0340621 SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED GASTROINTESTINAL DISORDERS
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof (Formula (I)) in which m, n, W, X, Y, Z, R.sup.1,...
2017/0340620 SUBLINGUAL OPIOID FORMULATIONS CONTAINING NALOXONE
Sublingual formulations containing an opioid, preferably, fentanyl or a pharmaceutically acceptable salt or ester thereof, naloxone or a pharmaceutically...
2017/0340619 METHODS OF TREATING BEHAVIORAL SYNDROMES USING PIPRADROL
Methods of treating behavioral syndromes by administering a pharmaceutical composition of pipradrol or a pharmaceutically acceptable salt thereof are provided....
2017/0340618 2-Amino-5,5-Difluoro-6-(Fluoromethyl)-6-Phenyl-3,4,5,6-Tetrahydropyridines as BACE1 Inhibitors
The present invention is directed to compounds of Formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to...
2017/0340617 PYRIDONE DERIVATIVES AS REARRANGED DURING TRANSFECTION (RET) KINASE INHIBITORS
This invention relates to novel compounds which are inhibitors of the Rearranged during Transfection (RET) kinase, to pharmaceutical compositions containing...
2017/0340616 AMINOESTER DERIVATIVES
Compounds of formula (I), defined herein, are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for the...
2017/0340615 COMPOSITIONS, METHODS AND KITS FOR REDUCING LIPID LEVELS
Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of...
2017/0340614 Compositions and Methods of Treating Muscular Dystrophy with Thromboxane-A2 Receptor Antagonists
The present invention is directed to methods of treating and/or ameliorating muscular dystrophy and/or treating cardiomyopathy in muscular dystrophy patients...
2017/0340613 Novel Imidazole-Based Heterocyclic Compounds
The present invention relates to novel compounds of formula (I) suitable e.g. as therapeutic agents for use in the treatment of mammalian disease and in...
2017/0340612 TREATMENT FOR CUTANEOUS T CELL LYMPHOMA
The present invention provides method for treating a patient with cutaneous T cell lymphoma (CTCL). Generally, the methods include administering to the patient...
2017/0340611 NOVEL COMPOUNDS
Pyrazolone derivatives of formula (I) defined herein exhibit human neutrophil elastase inhibitory properties and are useful for the treatment of diseases or...
2017/0340610 RORgammaT INHIBITORS
The present invention relates to compounds according to Formula (I) or a pharmaceutically acceptable salt or solvate thereof. Such compounds can be used in the...
2017/0340609 ANTIMICROBIAL AGENTS AND THE METHOD OF SYNTHESIZING THE ANTIMICROBIAL AGENTS
New 1,3-dipenyl pyrazole derived azomethines and N-aryl amines have been synthesized. These anti-MRSA agents combat MRSA and other infections. These azomethine...
2017/0340608 Compounds and Compositions That Bind and Stabilize Transthyretin and Their Use for Inhibiting Transthyretin...
Disclosed herein are compounds and compositions thereof which find use in increasing stability of proteins particularly proteins that tend to misfold and form...
2017/0340607 ANTIFUNGAL AGENTS
The invention provides a pyrrole compound, which compound is (a) 2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidin-2-yl)- ...
2017/0340606 METHODS OF TREATING MUSCULAR DYSTROPHY
Disclosed herein are .alpha.7.beta.1 integrin modulatory agents and methods of using such to treat conditions associated with decreased .alpha.7.beta.1...
2017/0340605 THERAPEUTIC COMPOUNDS AND USES THEREOF
The present invention relates to compounds of formula (I): ##STR00001## and to salts thereof, wherein R.sup.1, R.sup.2, and Q have any of the values defined in...
2017/0340604 THERAPEUTIC COMPOUNDS AND USES THEREOF
The present invention relates to compounds of formula (I): ##STR00001## and to salts thereof, wherein R.sup.1, R.sup.2, R.sup.c, and R.sup.d have any of the...
2017/0340603 COMPOSITIONS AND METHODS FOR SKIN CARE
Compositions and methods are for disclosed for treating a skin condition that results from reactive oxygen species production in skin of a subject, including...
2017/0340602 COMPOUNDS AND FORMS OF TREATMENT FOR FEMALE SEXUAL DISORDERS
The invention provides safe and efficacious treatments for Female Sexual Disorders, genitopelvic pain/penetration disorders; vulvovaginal atrophy, ...
2017/0340601 Composition for Prevention or Treatment of Cutaneous Disorder
The present invention relates to a pharmaceutical composition or medical device comprising a fucoidan and at least one compound of formula A or B: ##STR00001## ...
2017/0340600 COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or...
2017/0340599 BREAST CANCER THERAPY BASED ON HORMONE RECEPTOR STATUS WITH NANOPARTICLES COMPRISING TAXANE
The present invention relates to methods and kits for the treatment of breast cancer based on hormone receptor status of progesterone receptor and estrogen...
2017/0340598 Method of Reducing Uric Acid with Fucoxanthin-Containing Composition
The present invention provides a method of reducing uric acid in a subject in need thereof, comprising administering to the subject a composition comprising an...
2017/0340597 LONG ACTING PHARMACEUTICAL COMPOSITION OF PROTEASE INHIBITOR
Disclosed herein is a long acting pharmaceutical composition for treating or preventing human immunodeficiency virus (HIV) infection. The pharmaceutical...
2017/0340596 TREATMENT FOR OBESITY
The present invention relates to a method for treating or preventing obesity in a subject in need thereof, comprising administering to the subject a...
2017/0340595 Compositions and Methods for Treating Autism Spectrum Disorders
The instant disclosure features, among other things, compositions and methods for treating an autism spectrum disorder in a human. The compositions comprise an...
2017/0340594 PHARMACEUTICAL COMPOSITIONS FOR TREATING ACNE
The present application relates to pharmaceutical compositions comprising retinoic acid or its derivatives such as isotretinoin and processes for preparing...
2017/0340593 MEDICAMENTS FOR SLOWING PARKINSON'S DISEASE
Opicapone, levodopa and an AADC inhibitor are described for use in slowing the progression of Parkinson's Disease.
2017/0340592 Controlled Release Dosage Form
The present invention provides a simple and improved dose form that is capable of providing a controlled release of GABA.sub.B receptor agonist contained in...
2017/0340591 ALPHA-CELL RE-GENERATION COMBINED WITH CONVERSION TO BETA CELLS
The present invention relates to methods of generating a population of beta cells from a population of alpha cells, by contacting said population of alpha...
2017/0340590 AQUEOUS ANTIMICROBIAL COMPOSITION
A gel useful in reducing bacterial colonization in or around the area of a wound can be provided by combining at least one PEG with an aqueous composition...
2017/0340589 Treatment of intrahepatic cholestatic diseases
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
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