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Patent # Description
2017/0348356 MICROVESICLES (MVS) DERIVED FROM ADULT STEM CELLS FOR USE IN THE THERAPEUTIC TREATMENT OF A TUMOR DISEASE
The invention is in the field of therapeutic treatment of tumors. The inventors have found that microvesicles derived from adult stem cells exert a remarkable...
2017/0348355 LYOPHILIZED PLATELET LYSATES
The present disclosure is drawn to compositions and methods of making and using lyophilized platelet lysates. Specifically, a method of preparing a composition...
2017/0348354 LYOPHILIZED PLATELET LYSATES
The present disclosure is drawn to compositions and methods of making and using lyophilized platelet lysates. Specifically, a method of preparing a composition...
2017/0348353 FLOWABLE TISSUE MATRICES
Disclosed herein are flowable tissue matrix compositions comprising small pieces of partially or completely decellularized tissue suspended in a gelatinized...
2017/0348352 Zinc Phosphate Complex
A soluble zinc polyphosphate complex made by combining ingredients which include an inorganic zinc salt and a plurality of long chain polyphosphates having 6...
2017/0348351 DRUG BASED ON MAGHEMITE FOR SIMULTANEOUS REDUCTION OF GASTROINTESTINAL SODIUM RESORPTION AND PHOSPHATE RESORPTION
The invention includes a substance based on nanocrystalline maghemite having a crystal size of between 0.5 and 4 nm, which is defined by a proportion of...
2017/0348350 Novel Gold-Based Nanocrystals for Medical Treatments and Electrochemical Manufacturing Processes Therefor
The present invention relates to novel gold nanocrystals and nanocrystal shape distributions that have surfaces that are substantially free from organic...
2017/0348349 Modulation of Amyloid Beta Toxicity and Processing By Xenon Gas
Disclosed are the unique and unexpected findings that xenon gas possesses the ability to directly inhibited amyloid beta associated toxicity, inhibit...
2017/0348347 AGENT FOR IMPROVING OCULAR SUBJECTIVE SYMPTOMS AND METHOD THEREOF
Provided is an agent for improving human ocular subjective symptoms containing hyaluronic acid having an aminoalkyl cinnamate covalently bonded thereto.
2017/0348346 COMBINATION THERAPIES FOR INNER EAR SENSORY HAIR CELL REGENERATION/REPLACEMENT
The present disclosure relates to compositions and methods for the regeneration and/or restoration of hair cells utilizing a composition or an agent that...
2017/0348345 Combination Therapy For Cancer
A method of treating brain cancer in an immune-competent human patient by administering ternozolornide to the immune-competent human patient, the improvement...
2017/0348344 AQUEOUS OPHTHALMIC SOLUTION
Provided is an aqueous ophthalmic solution comprising diquafosol or a salt thereof at a concentration of 0.1% to 10% (w/v) and a chlorhexidine at a...
2017/0348343 METHODS OF TREATING HEPATITIS E VIRAL INFECTION
Disclosed herein are methods of treating a hepatitis E viral infection comprising administering to a human subject in need thereof a therapeutically effective...
2017/0348342 COMPOSITIONS AND METHODS FOR TREATING HEPATITIS C VIRUS
Disclosed herein are a composition and unit dosage form for the treatment of hepatitis C virus (HCV) infection comprising GS-7977 and at least one ...
2017/0348341 Metronomic Oral Gemcitabine for Cancer Therapy
The disclosure relates to compositions and methods for treatment, such as inducing regression or inhibiting growth, of tumors in a patient such as a human. Use...
2017/0348340 NEW C-GLYCOSYLPOLYPHENOL ANTIDIABETIC AGENTS, EFFECT ON GLUCOSE TOLERANCE AND INTERACTION WITH BETA-AMYLOID....
The present invention concerns the antidiabetic activity of compounds type A, namely of 8-.beta.-D-glucosylgenistein, which is not toxic to eukaryotic cells...
2017/0348339 COMPOSITIONS AND METHOD OF USE OF A-TYPE PROCYANIDINS
The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing A-type procyanidins, and methods of...
2017/0348338 TREATMENT OF INFLAMMATORY CONDITIONS BY MODULATION OF HYALURONAN AND HYALURONIDASE ACTIVITY
The present invention describes compositions and related methods and kits for treating a variety of inflammatory conditions and infections. The therapeutic...
2017/0348337 MULTIFUNCTIONAL MEMBRANE-ACTIVE AMINOGLYCOSIDE-PEPTIDE CONJUGATES
Compositions and methods are disclosed that relate to aminoglycoside-linker-peptide (P-L-A) conjugates having unexpectedly advantageous dual-function...
2017/0348336 METHOD OF TREATING MELANOMA USING AN INHIBITOR OF AN ATYPICAL PROTEIN KINASE C
The invention pertains to a method of treating melanoma by administering to a subject in need thereof, a composition comprising a therapeutically effective...
2017/0348335 Physiologically Balanced Injectable Formulations of Fosnetupitant
Injectable dosages and formulations of fosnetupitant and pharmaceutically acceptable salts thereof are provided that are efficacious, chemically stable and...
2017/0348334 PROCESSES FOR THE PREPARATION OF AMORPHOUS TENOFOVIR ALAFENAMIDE HEMIFUMARATE AND A PREMIX THEREOF
An amorphous form of tenofovir alafenamide hemifumarate and process for the preparation of the same. A premix of amorphous tenofovir alafenamide hemifumarate...
2017/0348333 DRY POWDER FORMULATIONS FOR INHALATION
A respirable dry powder can include acetylsalicylic acid in particles having a mass median aerodynamic diameter (MMAD) within a range of about 0.5 .mu.m to...
2017/0348332 SALICYLATE COMPOUND COMPOSITION
A liquid composition contains a salicylate compound (e.g. aspirin), glycerin triacetate, saccharin. The salicylate compound is soluble in the composition,...
2017/0348331 METHODS AND COMPOSITIONS FOR MODULATING SEROTONIN LEVELS
The present application in one aspect provides methods and compositions that are fine-tuned to modulate brain and peripheral serotonin levels, which in turn...
2017/0348330 ANTIVIRAL COMPOUND AND ANALOGUES THEREOF FOR TREATMENT OR PREVENTION OF FLAVIVIRUS DENGUE/ZIKA INFECTIONS
The present invention provides for an antiviral compound and analogues thereof for treatment or prevention of Flavivirus Dengue/Zika infections. In general the...
2017/0348329 Combination Drug Therapy
A novel combination comprising the 17 .alpha.-hydroxylase/C17,20 lyase inhibitor, (3.beta.)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol or a pharmaceutically...
2017/0348328 Abiraterone Acetate Formulation and Methods of Use
Pharmaceutical compositions, including unit dosage forms, comprising abiraterone acetate and methods for producing and using such compositions are described.
2017/0348327 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF
Described herein are methods of treating tremor, e.g., essential tremor; depression, e.g., postpostum depression; and anxiety disorder, the method comprising...
2017/0348326 NEUROACTIVE STEROID FORMULATIONS AND METHODS OF TREATING CNS DISORDERS
Formulations of comprising a neuroactive steroid, e.g., allopregnanolone; and optionally a cyclodextrin, e.g., a .beta.-cyclodextrin, e.g., a sulfo butyl ether...
2017/0348325 OXYTOCIN RECEPTOR ANTAGONIST THERAPY IN THE LUTEAL PHASE FOR IMPLANTATION AND PREGNANCY IN WOMEN UNDERGOING...
The present invention relates to the use of an oxytocin receptor antagonist in females undergoing embryo transfer as part of an assisted reproductive...
2017/0348324 DERIVATIVES OF BETULIN
The present invention relates to compounds characterized by having a structure according to the following Formula I: ##STR00001## , or a pharmaceutically...
2017/0348323 METHODS AND MEDICAL USES
There is provided a method of treatment of hypersomnolence comprising administering the steroidal compound ...
2017/0348322 BK Channels as Non-Genomic Estrogen Targets for Overactive Bladder
Using BK Channels as non-genomic estrogen targets in order to alleviate overactive bladder.
2017/0348321 Wafer Comprising Steroid Hormones
The invention relates to a pharmaceutical composition in the form of a system in film form for transmucosal administration of steroid hormones. An...
2017/0348320 IMIDAZOLOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASE
Compounds, compositions and methods are provided for modulating the activity of receptor kinases and for the treatment, prevention, or amelioration of one or...
2017/0348319 4-OXO-3,4-DIHYDRO-1,2,3-BENZOTRIAZINE MODULATORS OF GPR139
The present invention provides a method for treating a disease, disorder or condition associated with GPR139 using compounds of formula 1: ##STR00001## which are...
2017/0348318 N,6-BIS(ARYL OR HETEROARYL)-1,3,5-TRIAZINE-2,4-DIAMINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT...
Provided are compounds of formula (I), Wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl....
2017/0348317 Treatment of Solid Tumours
A cell permeable iron chelator, optionally in combination with an autophagy inhibiting agent, is used for treating a solid cancer tumour in a person. A...
2017/0348316 ANIMAL AND HUMAN ANTI-MALARIAL AGENTS
Provided herein are Purine Comounds of Formula (I) ##STR00001## or pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof,...
2017/0348315 ANIMAL AND HUMAN ANTI-TRYPANOSOMONAL AND ANTI-LEISHMANIA AGENTS
Provided herein are Aminopurine compounds of Formula I: ##STR00001## or pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof,...
2017/0348314 COMBINATION THERAPIES
Provided herein are pharmaceutical compositions comprising a phosphatidylinositol 3-kinase inhibitor, or pharmaceutically acceptable form thereof, in...
2017/0348313 SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS
Compounds of the general formula): ##STR00001## processes for the preparation of these compounds, compositions containing these compounds, and the uses of these...
2017/0348312 TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF
A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or...
2017/0348311 TOPICAL FORMULATIONS OF PDE-4 INHIBITORS AND THEIR METHODS OF USE
Embodiments herein are directed to topical formulations of a compound represented by the formula (I), salt, metabolite, prodrug, or hydrate thereof along with...
2017/0348310 SERINE/THREONINE KINASE INHIBITORS
Compounds of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of...
2017/0348309 BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the...
2017/0348308 CONTROLLED RELEASE STERILE INJECTABLE ARIPIPRAZOLE FORMULATON AND METHOD
A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle...
2017/0348307 METHODS AND COMPOSITIONS FOR KILLING SENESCENT CELLS AND FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic...
2017/0348306 METHODS OF TREATING CANCER
This invention relates to methods of treating cancer in a subject in need thereof, e.g., in a human in need thereof, comprising determining at least one of the...
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