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Patent # Description
2017/0349924 METHOD OF PRODUCING LIQUID COMPOSITIONS
The present invention relates to methods of processing mixtures comprising .beta.-glucans and polysaccharides.
2017/0349923 PLUG FLOW HYDROLYSIS REACTOR AND PROCESS OF USING SAME
Provided herein is a process for hydrolyzing a cellulosic feedstock to produce sugar. The process comprises introducing a pretreated cellulosic slurry to an...
2017/0349922 COMPOSITIONS AND METHODS RELATED TO BETA-GLUCOSIDASE
The present compositions and methods relate to a beta-glucosidase from Glomerella graminicola, polynucleotides encoding the beta-glucosidase, and methods of...
2017/0349921 SYNTHESIS OF LONG-CHAIN POLYUNSATURATED FATTY ACIDS BY RECOMBINANT CELL
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and...
2017/0349920 NOVEL PICHIA KUDRIAVZEVII NG7 MICROORGANISM AND USES THEREOF
The present invention relates to: a novel Pichia kudriavzevii microorganism NG7 showing heat resistance and acid resistance; a composition, for producing...
2017/0349919 MICRO-ORGANISM FOR THE PRODUCTION OF STEREO-SPECIFIC S, S-2,3-BUTANEDIOL
The invention relates to a genetically modified lactic acid bacterium capable of producing (S,S)-2,3-butanediol stereo specifically from glucose under aerobic...
2017/0349918 ENZYMATIC METHODS FOR ISOBUTANOL PRODUCTION
The present invention relates to a process of producing isobutanol, including: mixing water, lactate, an enzyme mixture including at least one enzyme, at least...
2017/0349917 HIGHLY EFFICIENT ETHANOL-FERMENTATIVE YEAST
An object of the present invention is to obtain a fermentative yeast having a highly efficient ethanol production without introducing a foreign gene. A further...
2017/0349916 ADDITIVE FOR BIOETHANOL FERMENTATION PROCESS AND METHOD FOR PRODUCING BIOETHANOL
There is provided an additive for a bioethanol fermentation process comprising a polyoxyalkylene compound (A) having a Griffin's HLB value in the range of 0 to...
2017/0349915 CRISPR HYBRID DNA/RNA POLYNUCLEOTIDES AND METHODS OF USE
The present disclosure provides DNA-guided CRISPR systems; polynucleotides comprising DNA, RNA and mixtures thereof for use with CRISPR systems; and methods of...
2017/0349914 DELIVERY, USE AND THERAPEUTIC APPLICATIONS OF CRISPR SYSTEMS AND COMPOSITIONS FOR GENOME EDITING AS TO...
The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of...
2017/0349913 USING PROGRAMMABLE DNA BINDING PROTEINS TO ENHANCE TARGETED GENOME MODIFICATION
Compositions and methods for using programmable DNA binding proteins to increase the efficiency and/or specificity of targeted genome modification or to...
2017/0349912 SYSTEMS AND METHODS FOR CELL TRANSDUCTION
Systems and methods are disclosed herein for use in transducing, activating, and otherwise treating cells. Cells are introduced into an inner layer of a...
2017/0349911 CNS TARGETING AAV VECTORS AND METHODS OF USE THEREOF
The invention in some aspects relates to recombinant adeno-associated viruses useful for targeting transgenes to CNS tissue, and compositions comprising the...
2017/0349910 WOODY PLANTS HAVING IMPROVED GROWTH PROPERTIES
The invention relates to a method for producing a genetically modified woody plant with improved growth properties (in terms of biomass and/or wood density) as...
2017/0349909 Modulation of Expression of Acyltransferases to Modify Hydroxycinnamic Acid Content
The invention provides methods of engineering plants to modulate hydroxycinnamic acid content. The invention additionally provides compositions and methods...
2017/0349908 MODULATING THE LEVEL OF COMPONENTS WITHIN PLANTS
Materials and methods for identifying lignin regulatory region-regulatory protein associations are disclosed. Materials and methods for modulating lignin...
2017/0349907 Methods to Monitor Post-Translational Gene Silencing Activity in Plant Tissues/Cell Types Relevant for Pathogen...
The invention relates to transgenic plants comprising an inverted-repeat construct which triggers post-transcriptional gene silencing of an endogenous visual...
2017/0349906 EXPRESSION CONSTRUCTS AND METHODS OF GENETICALLY ENGINEERING METHYLOTROPHIC YEAST
Methods and materials for genetically engineering methylotrophic yeast are provided.
2017/0349905 GENOME EDITING WITH SPLIT CAS9 EXPRESSED FROM TWO VECTORS
The present invention relates to a method for regulating gene expression, comprising introducing into a cell each of a recombinant vector which expresses a...
2017/0349904 Methods and Compositions for Selecting siRNA of Improved Functionality
Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize...
2017/0349903 siRNA COMPOSITIONS THAT SPECIFICALLY DOWNREGULATE EXPRESSION OF A VARIANT OF THE PNPLA3 GENE AND METHODS OF USE...
The invention provides siRNA compositions that specifically downregulates expression of a variant of the PNPLA3 gene and methods of use thereof for treating a...
2017/0349902 SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR INHIBITING TGF-BETA1 EXPRESSION
The invention provides a single-stranded nucleic acid molecule of (A) or (B) containing a TGF-.beta.1 gene expression inhibitory sequence. The single-stranded...
2017/0349901 HEPATITIS D VIRUS (HDV) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the hepatitis D virus (HDV) genome, and methods of using such RNAi...
2017/0349900 HEPATITIS B VIRUS (HBV) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the hepatitis B virus (HBV) genome, and methods of using such RNAi...
2017/0349899 FUNGAL CHROMOSOME-END KNOCKOFF STRATEGY
Non-toxigenic fungal strains, and methods of making and use thereof, are provided and have utility as endophytes in forage crops, and as strains that can...
2017/0349898 IMMUNOMODULATION BY CONTROLLING ELR+ PROINFLAMMATORY CHEMOKINE LEVELS WITH THE LONG NON-CODING RNA UMLILO
The present invention relates to methods for modulating the production of ELR+ proinflammatory chemokines in a subject or a cell using either UMLILO IncRNA...
2017/0349897 COMPOSITIONS FOR MODULATING C9ORF72 EXPRESSION
Disclosed herein are compositions and methods for reducing expression of C9ORF72 mRNA and protein in an animal. Such methods are useful to treat, prevent,...
2017/0349896 POLY OLIGOMER COMPOUND WITH BIOCLEAVABLE CONJUGATES
The invention relates to the field of oligonucleotide therapeutics, and in particular to poly oligo oligonucleotides conjugates where two or more antisense...
2017/0349895 NUCLEASE-RESISTANT DNA ANALOGUES
The present invention provides stable, nuclease-resistant TNA, TNA-DNA and TNA-RNA oligonucleotides, wherein the oligonucleotides are completely resistant to...
2017/0349894 ESCORTED AND FUNCTIONALIZED GUIDES FOR CRISPR-CAS SYSTEMS
The present invention generally relates to CRISPR systems or complexes, such as those with an escorted guide RNA.
2017/0349893 METHOD AND REAGENT FOR CONSTRUCTING NUCLEIC ACID DOUBLE-LINKER SINGLE-STRAND CYCLICAL LIBRARY
A method and reagent for constructing a nucleic acid double-joint single-strand cyclical library. The method comprises: breaking a nucleic acid into nucleic...
2017/0349892 Propiconazole resistant mutants of Chlorella Species
The present disclosure relates to propiconazole resistant mutants of Chlorella sp. having Accession No. CCAP 211/133. The propiconazole resistant mutants of...
2017/0349891 Universal Platform for Genetic Code Expansion
Methods and compositions are described for selecting and identifying orthogonal aminoacyl synthetase-tRNA pairs and their use to incorporate unnatural amino...
2017/0349890 PROTEASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding...
2017/0349889 CRYSTAL STRUCTURE OF HUMAN FOUR-PHOSPHATE ADAPTOR PROTEIN 2 GLYCOLIPID TRANSFER PROTEIN LIKE DOMAIN
In some embodiments, the present invention provides method of identifying compounds that bind to phosphoinositol 4-phosphate adaptor protein-2 (FAPP2),...
2017/0349888 PROCESS FOR THE PRODUCTION OF CELLULOLYTIC AND/OR HEMICELLULOLYTIC ENZYMES
The process for the production of cellulolytic and/or hemicellulolytic enzymes by a cellulolytic and/or hemicellulolytic microorganism according to the present...
2017/0349887 Alpha-Amylases and Polynucleotides Encoding Same
The present disclosure relates to isolated polypeptides having alpha-amylase activity, polynucleotides encoding the polypeptides, nucleic acid constructs,...
2017/0349886 LIGAND BINDING MOLECULES AND USES THEREOF
The present invention is directed to polynucleotides that encode VEGFR-3 ligand binding molecules and uses thereof to modulate angiogenesis and/or ...
2017/0349885 PROTEIN COMPLEX CAPABLE OF CATALYZING ASYMMETRIC OXIDATION REACTION AND METHOD FOR PRODUCING SAME
Provided are: a protein complex capable of selectively and asymmetrically oxidizing an enantiomer of a secondary alcohol without adding a coenzyme and having...
2017/0349884 Production of Differentiated Enteroendocrine Cells and Insulin Producing Cells
A population of enteroendocrine cells (EEC) is obtained from a mammalian post-natal cell population, such as a population including post-natal stem cells, by...
2017/0349883 MATURE CARDIAC MUSCLE CELL MARKER
From a cell population containing cardiomyocytes, the cardiomyocytes are extracted using a marker(s) specific to cardiomyocytes, that is, at least one marker...
2017/0349882 CELL CULTURE SUBSTRATE FOR TRAIT INDUCTION CONTROL OF MACROPHAGE AND METHOD OF CONTROLLING TRAIT OF MACROPHAGE
Provided is a cell culture substrate for trait induction control of a macrophage, which has a pattern of unevenness on a surface to which a cell adheres, the...
2017/0349881 TRAIT INDUCTION METHOD OF UNDIFFERENTIATED CELLS
A trait induction method of undifferentiated cells is provided, including: culturing undifferentiated cells on abase material which has an uneven pattern on...
2017/0349880 ADOPTIVE IMMUNOTHERAPY FOR TREATING CANCER
The present invention provides methods for producing and/or expanding tumor-infiltrating lymphocytes (TILs) that can be used in adoptive immunotherapy in...
2017/0349879 METHOD FOR CULTURING NORMAL CELLS AND ODONTOMA CELLS CONTAINED IN ORAL TISSUE
The present invention provides a method for culturing odontoma cells or normal cells, wherein these cells are cultured in the presence of a Rho kinase inhibitor.
2017/0349878 CELL CULTURE MEDIA
A cell culture medium comprising adenosine triphosphate; a carrier protein; cholesterol, linoleic acid, and lipoic acid; glutathione; at least one nucleotide...
2017/0349877 CELL CULTURE SUBSTRATE FOR TRAIT INDUCTION OF NERVE CELL, METHOD OF CONTROLLING TRAIT OF NERVE CELL, METHOD OF...
Provided is a cell culture substrate for trait induction of a nerve cell, which has a pattern of unevenness on a surface to which a cell adheres, the width of...
2017/0349876 BIOACTIVE BOROPHOSPHATE GLASSES
A borophosphate glass composition including B.sub.2O.sub.3, P.sub.2O.sub.5, and CaO, and optionally a source additive selected from: Li.sub.2O, Na.sub.2O,...
2017/0349875 Cell Separation Devices, Systems, and Methods
Disclosed herein are cell separation devices, methods and systems, as well as compositions and reagents for use in cell separation methods.
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