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Patent # Description
2017/0349571 POSITIVE ALLOSTERIC MODULATORS OF HUMAN MELANOCORTIN-4 RECEPTOR
Disclosed herein are positive allosteric modulators of melanocortin receptor and methods of using such modulators.
2017/0349570 NEW SUBSTITUTED INDAZOLES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SAID...
The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment...
2017/0349569 Novel Process for Making Compounds for Use in the Treatment of Cancer
Disclosed herein is a process of making a compound of formula I ##STR00001## The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
2017/0349568 2-MORPHOLIN-4,6-DISUBSTITUTED PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF
Disclosed is a 2-morpholin-4,6-disubstituted pyrimidine derivative as shown in formula (1) below, and a pharmaceutically acceptable salt, solvate, stereoisomer...
2017/0349567 Halogenated S-(perfluoroalkyl)dibenzothiophenium salt and its production methods
Halogenated S-(perfluoroalkyl)dibenzothiophenium salt represented by the following general formula (I): ##STR00001## This compound is a new, reactive, and...
2017/0349566 AN EFFICIENT PROCESS FOR THE SYNTHESIS OF ALKOXY SUBSTITUTED BENZALDEHYDES
The present invention relates to the synthesis of alkoxy substituted benzaldehydes obtained from the corresponding alkoxy substituted benzenes. Alkoxy...
2017/0349565 ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES
The disclosure relates to special orthoformic acid esters of formula (I), as defined herein, which can be used as thermally labile and acid-labile fragrance...
2017/0349564 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, PATTERN...
A compound represented by the following formula (1): ##STR00001## wherein each X independently represents an oxygen atom or a sulfur atom, or non-crosslinking,...
2017/0349563 FORMATION OF CHROMANES BASED ON INTERMOLECULAR REACTION OF ALKYNES WITH DIMETHYLFURAN IN THE PRESENCE OF...
The present invention relates to a method of preparing chromanes from 2,5-dimethylfuran and substituted alkynes comprising an long chain unsaturated alkyl...
2017/0349562 USE OF SMALL MOLECULE INHIBITORS TARGETING EYA TYROSINE PHOSPHATASE
Inhibitors of EYA tyrosine phosphatase are provided herein, as well as pharmaceutical compositions and methods relating thereto.
2017/0349561 SYNTHESIS OF NOVEL IONIC LIQUIDS FROM LIGNIN-DERIVED COMPOUNDS
Methods and compositions are provided for synthesizing ionic liquids from lignin. Methods and compositions are also provided for treating lignin with ionic...
2017/0349560 14-HYDROXY-DOCOSAHEXAENOIC ACID COMPOUNDS
The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogues, their preparation, isolation, identification, purification and uses thereof.
2017/0349559 5-HT2B Antagonists
The invention provides novel compounds and compositions comprising a 5-HT.sub.2B antagonist of formula I: ##STR00001## and related methods for treating a person...
2017/0349558 SUBSTITUTED TRIAZOLES AND METHODS RELATING THERETO
Substituted 1,2,3-triazole compounds are disclosed which have utility in the treatment of a variety of neurological disorders. The compounds provided herein...
2017/0349557 HETEROCYCLIC SUBSTITUTED 2-AMINO QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS
This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use...
2017/0349556 INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic...
2017/0349555 INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic...
2017/0349554 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE
This invention relates to the use sigma-2 receptor antagonists, and of pharmaceutical compositions comprising such compounds, in methods for inhibiting...
2017/0349553 SMALL- MOLECULE INHIBITORS TARGETING G-PROTEIN-COUPLED RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS
Provided are inhibitors of Rho GTPase activation, and, in particular, compounds that inhibit RhoA activation by an RhoGEF. Also provided are related...
2017/0349552 Treatment of Amyotrophic Lateral Sclerosis
The present invention relates to the identification of compounds and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral...
2017/0349551 N-(4-HYDROXY-4-METHYL-CYCLOHEXYL)-4-PHENYL-BENZENESULFONAMIDE AND ...
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted...
2017/0349550 ACTIVE COMPOUND COMBINATIONS
The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a difluoromethyl-nicotinic...
2017/0349549 PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-CHLORO-6-(SUBSTITUTED)PICOLINATES
4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a 3,3-dialkoxyprop-1-yne and a substituted...
2017/0349548 P21-ACTIVATED KINASE INHIBITOR
The present invention addresses the problem of providing an inhibitor which has an excellent inhibitory activity on a p21-activated kinase. The present...
2017/0349547 CONDUCTING REACTIONS IN LEIDENFROST-LEVITATED DROPLETS
The invention generally relates to conducting reactions in Leidenfrost-levitated droplets.
2017/0349546 Light-Activated Two-Component Protein Binding Matrix
A binding pair for chromatographic separation or purification of a molecule of interest, where one binding member of the pair is an isomerizable organic...
2017/0349545 METHOD FOR PRODUCING NITROGEN-CONTAINING PENTAFLUOROSULFANYLBENZENE COMPOUND
A method for producing a nitrogen-containing pentafluorosulfanylbenzene compound of formula (2a) or (2b): ##STR00001## (wherein R.sup.1 a hydrogen atom or a...
2017/0349544 Ethynylbenzene Derivatives
Disclosed are compounds of formulae (I), (II), and (II)I: and pharmaceutically acceptable salts thereof, wherein the variables, R, R.sub.1, R.sub.2, R.sub.3,...
2017/0349543 CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS
The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas: ...
2017/0349542 ZERO EMISSION UREA PROCESS AND PLANT
Disclosed is a method for the production of urea allowing a substantial reduction, even down to zero, of the continuous emission of ammonia conventionally...
2017/0349541 METHODS FOR TREATING FIBROMYALGIA SYNDROME
The invention is directed to a method of treating fibromyalgia syndrome in a subject, comprising administering a therapeutically effective amount of a...
2017/0349539 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC SUBSTANCE
The present invention relates to: a polymerizable compound represented by a formula (I); a polymerizable composition comprising the polymerizable compound and...
2017/0349538 Blood Brain Barrier-Penetrating Oximes for Cholinesterase Reactivation
The invention describes pharmaceutical agents capable of crossing the blood brain barrier to protect against organophosphate pesticides and nerve agents or...
2017/0349537 INHIBITORS OF LYSINE GINGIPAIN
The present invention relates generally to therapeutics targeting the bacterium Porphyromonas gingivalis, including its protease Lysine gingipain (Kgp), and...
2017/0349536 Natural Oil Derivatives Including (Meth)acrylate Functional Groups
A compound has Structure I: ##STR00001## where R.sub.1 and R.sub.2 independently are C.sub.2-C.sub.12 alkyl groups, R.sub.3 and R.sub.3' independently are H or...
2017/0349535 MATERIALS AND METHODS FOR THE SELECTIVE RECOVERY OF MONOVALENT PRODUCTS FROM AQUEOUS SOLUTIONS USING CONTINUOUS...
This document describes a process for the high purity and high concentration recovery of monovalent products via continuous ion exchange from aqueous solution...
2017/0349534 A NOVEL PROCESS FOR CHIRAL RESOLUTION OF HIGHLY PURE (6R)-6-(DIMETHYLAMINO)-4,4-DIPHENYL-HEPTANONE FROM RACEMIC...
The present invention discloses an improved process for preparing pure (6R)-6-(dimethylamino)-4,4-diphenyl-3-heptanone and its hydrochloride salt.
2017/0349533 STABLE SOLID FORMS OF ENCLOMIPHENE AND ENCLOMIPHENE CITRATE
The present invention refers to new solid forms of Enclomiphene citrate and Enclomiphene base, processes for preparing thereof and uses.
2017/0349532 CATIONIC LIPID
The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I) (wherein: R.sup.1 and...
2017/0349531 Dibasic Esters and the Use Thereof in Plasticizer Compositions
Dibasic esters (diesters) and their use in plasticizer compositions are generally disclosed. In some embodiments, the diesters are branched-chain esters of...
2017/0349530 METHOD AND APPARATUS FOR PURIFICATION OF DIMETHYL CARBONATE USING PERVAPORATION
An apparatus for separating dimethyl carbonate using pervaporation includes: an atmospheric distillation column and a high pressure distillation column...
2017/0349529 Method to Prepare Phenolics from Biomass
The present invention is directed to a method for preparing a final phenolic product from biomass comprising the steps of providing a furanic compound...
2017/0349528 PROCESS FOR PRODUCING ETHYL ESTERS OF POLYUNSATURATED FATTY ACIDS
The present invention relates to a process for producing ethyl esters of polyunsaturated fatty acids, comprising transesterifying triacylglycerols in extracted...
2017/0349527 PROCESS FOR PRODUCING ETHYL ESTERS OF POLYUNSATURATED FATTY ACIDS
The present invention relates to a process for producing ethyl esters of polyunsaturated fatty acids, comprising transesterifying triacylglycerols in extracted...
2017/0349526 PROCESS FOR PRODUCING ETHYL ESTERS OF POLYUNSATURATED FATTY ACIDS
The present invention relates to a process for producing ethyl esters of polyunsaturated fatty acids, comprising transesterifying triacylglycerols in extracted...
2017/0349525 LACTYLATE PURIFICATION PROCESS
A method for separation of fatty acid from a mixture having fatty acid, the corresponding acyl lactylate and lactic acid, method having steps of: a) providing...
2017/0349524 Cycloalkane oxidation catalysts and method to produce alcohols and ketones
The present invention concerns a method of oxidizing a cycloalkane to form a product mixture containing a corresponding alcohol and ketone, said method...
2017/0349523 Methods for the Production of Alpha,Beta-Unsaturated Carboxylic Acids and Salts Thereof
Processes for producing an .alpha.,.beta.-unsaturated carboxylic acid, such as acrylic acid, or a salt thereof, using solid promoters are disclosed. The solid...
2017/0349522 PROCESSES FOR PRODUCING AN ACETIC ACID PRODUCT HAVING LOW BUTYL ACETATE CONTENT
A process for producing an acetic acid product having low butyl acetate content via a carbonylation reaction. The carbonylation reaction is carried out at a...
2017/0349521 METHOD FOR PRODUCING ACETIC ACID
A method produces acetic acid and includes a reaction step, a first purification step, a second purification step, and a third purification step. In the...
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