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Patent # Description
2017/0354729 VACCINE COMPOSITIONS CONTAINING MODIFIED ZIKA VIRUS ANTIGENS
The present disclosure relates to vaccine compositions that comprise a Zika virus antigen and an adjuvant. The present disclosure also provides methods for...
2017/0354728 ANTIGEN SPECIFIC MULTI EPITOPE-BASED ANTI-INFECTIVE VACCINES
The invention provides peptide vaccines comprising the signal peptide domain of selected target antigens of intracellular pathogens. The peptide vaccines of...
2017/0354727 MODULATION OF REPLICATIVE FITNESS BY DEOPTIMIZATION OF SYNONYMOUS CODONS
Methods of producing a pathogen with reduced replicative fitness are disclosed, as are attenuated pathogens produced using the methods. In particular examples,...
2017/0354726 CANCER PEPTIDE VACCINE
A composition for treating cancer, comprising 6 to 13 peptides derived from tumor antigens, wherein the composition is used in the manner that antibodies to...
2017/0354725 COMBINATORIAL ANDROGEN DEPRIVATION WITH AN ANDROGEN RECEPTOR VACCINE
It is disclosed herein methods of treating prostate cancer comprising administering to the subject the combination of androgen deprivation therapy (ADT) and a...
2017/0354724 COMPOSITIONS AND METHODS FOR IMPROVED CAR-T CELL THERAPIES
The present invention relates to the preparation and use in recipients of CAR-T cell-derived effector cells which are modified to limit their proliferation...
2017/0354723 COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION
The present invention relates to compositions and methods for cell transplantation. In particular, the present invention provides a composition with...
2017/0354722 COMPOSITIONS AND METHODS FOR TREATING POST-OPERATIVE COMPLICATIONS OF CARDIOPULMONARY SURGERY
Compositions and methods for treating damage inflicted by use of a cardio-pulmonary bypass (CPB) machine, particularly excessive bleeding and multi organ...
2017/0354721 WOUND HEALING COMPOUND
The invention presented is an injectable wound healing compound that includes at least one antibiotic, a hemostatic agent, and an injectable flowable matrix....
2017/0354720 Novel Class of Therapeutic Protein Based Molecules
The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides...
2017/0354719 Compositions and Methods for Treating Pathological Calcification and Ossification
The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological...
2017/0354718 FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN
The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in...
2017/0354717 METHODS AND MEANS FOR DETERMINING TREATMENT OF SUBJECTS WITH EXOGENOUS SOMATOTROPIN
Described are methods for determining whether a subject has been treated with exogenous somatotropin. The disclosure further relates to kits for determining...
2017/0354716 Novel Polymeric hGH Prodrugs
The present invention relates to a polymeric human growth hormone prodrug and dry, liquid and reconstituted pharmaceutical formulations comprising said...
2017/0354715 TREATMENT OF THROMBOCYTOPENIA USING ORALLY ADMINISTERED INTERFERON
An interferon composition is provided for enhancing the platelet count, reducing the recurrence rate of hepatitis, and/or improving the social function of...
2017/0354714 ANTI-OBESITY AND ANTI-DIABETIC EFFECTS OF ANGIOPOIETIN-LIKE 4 (ANGPTL4) FIBRINOGEN-LIKE DOMAIN
Angiopoietin-like 4 (Angpt14) is a secreted protein that inhibits lipoprotein lipase (LPL) activity and promotes lipolysis in adipocytes. The present methods...
2017/0354713 FGF21 Derivatives and Uses Thereof
The invention relates to a derivative of a FGF21 protein having a cysteine residue at a position corresponding to position 167, 169, 170, 171, 172, 173, 174,...
2017/0354712 BPI AND ITS CONGENERS AS RADIATION MITIGATORS AND RADIATION PROTECTORS
Described herein is a method of mitigating, in a subject (individual), tissue injury resulting from exposure to radiation (accidental/unintentional or...
2017/0354711 HIGH DENSITY LIPOPROTEIN NANOPARTICLES FOR INFLAMMATION
The invention in aspects relates to methods of treating sepsis using HDL-NP. The methods include the use of nanoparticles having a core and a lipid based shell...
2017/0354710 METHODS OF USING GAP JUNCTIONS AS THERAPEUTIC TARGETS FOR THE TREATMENT OF DEGENERATIVE DISORDERS OF THE RETINA
The disclosure provides methods of treating a condition of the retina by administering an inhibitor of connexin 36 and/or an inhibitor of connexin 45 to a...
2017/0354709 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE...
The present invention relates to methods and pharmaceutical compositions for the treatment of acute exacerbation of chronic obstructive pulmonary disease. In...
2017/0354708 PEPTIDE CONGENERS WITH POLYMER EXCIPIENTS
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2017/0354707 CHEMICAL REPROGRAMMING OF HUMAN GLIAL CELLS INTO NEURONS FOR BRAIN AND SPINAL CORD REPAIR
Provided are methods and compositions from reprogramming human glial cells into human neurons. The reprogramming is achieved using combinations of compounds...
2017/0354706 HYBRID PROTEINACEOUS MOLECULE CAPABLE OF INHIBITING AT LEAST ONE ANTIBIOTIC AND PHARMACEUTICAL COMPOSITION...
The invention relates to a hybrid proteinaceous molecule comprising at least two proteins capable of inhibiting the activity of at least one antibiotic, the...
2017/0354705 HAND SANITIZER COMPOSITION AND METHOD OF MANUFACTURE
A hand sanitizing composition and a method of manufacture, wherein the composition includes a solvent from about 78% to about 96% by weight sufficient to...
2017/0354704 BIOLOGICALLY-ACTIVE TOMATO COMPOSITION HAVING REDUCED AMOUNT OF LYCOPENE
The present invention provides a composition comprising lycopene, one or both of phytoene and phytofluene, and phytosterols, wherein the concentration of...
2017/0354703 ANTI-GOUT COMPOSITION CONTAINING MIXED EXTRACT OF CHRYSANTHEMUM INDICUM AND CINNAMOMUM CASSIA AS ACTIVE INGREDIENT
An anti-gout composition including the mixed extract of Chrysanthemum indicum and Cinnamomum cassia as an active ingredient shows substantially greater...
2017/0354702 DRUG CONTAINING THYME AND PRIMROSE OR THYME AND IVY AS A PDE-4 INHIBITOR
The invention relates to an extract from thyme (Thymus L.) in combination with primrose (Primula veris) or ivy (Hedera helix) for use as PDE-4 inhibitor in the...
2017/0354700 CHINESE MEDICINAL COMPOSITION FOR PREVENTING OR TREATING CARDIOVASCULAR AND CEREBROVASCULAR DISEASES OR...
Disclosed are a Chinese medicinal composition for preventing or treating cardiovascular and cerebrovascular diseases and/or dementia, and a preparation method...
2017/0354699 EUGLENA LYSATE COMPOSITION
A composition includes a Euglena lysate and cellular components and residual media remaining from a fermentation process that produced a Euglena biomass and...
2017/0354698 METHOD OF PRODUCING A EUGLENA LYSATE
A method for producing a Euglena lysate includes growing a biomass from genus Euglena organisms, dewatering the grown biomass, lysing the biomass, and drying...
2017/0354697 TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTION
Provided herein are compositions and methods for the treatment or prevention of pathogenic infections.
2017/0354696 INFANT FORMULA WITH RRR-ALPHA-TOCOPHEROL, 2'-FUCOSYLLACTOSE, AND A PROBIOTIC
Infant formulas that include a combination of RRR-alpha-tocopherol, 2'-fucosyllactose, and at least one probiotic from the Lactobacillus or the Bifidobacterium...
2017/0354695 COMPOSITIONS COMPRISING BACTERIAL STRAINS
The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
2017/0354694 KRILL OIL PREPARATIONS WITH OPTIMAL MINERAL AND METAL COMPOSITION, LOW IMPURITIES AND LOW AND STABLE TMA LEVELS
A Krill oil preparation including a reduced amount of trimethylamine of 5 mgN/100 g or less, or more than 700 ppm by weight of endogenous calcium and/or less...
2017/0354693 CELL-BASED COMPOSITION AND USE THEREOF FOR TREATMENT OF MACULAR OEDEMA AND DEGENERATION
A method for the treatment of macular oedema and degeneration in a subject by administering to said subject an effective amount of a cell-based composition...
2017/0354692 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS
Formulations of human amniotic fluid and methods of use thereof for treatment of lung disorders, and/or injuries have been developed. The formulations are...
2017/0354691 CO-ENCAPSULATION OF LIVE CELLS WITH OXYGEN-GENERATING PARTICLES
Microcapsules are described that comprise (a) a liquid aqueous or hydrogel core; (b) a semipermeable membrane surrounding said core; (c) live animal cells...
2017/0354690 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved...
2017/0354689 SYSTEMS FOR CHARACTERIZATION OF THE CONTENTS OF THE LARGE INTESTINE AND TREATMENT OF CONDITIONS OF THE LARGE...
Systems are provided which analyze the large intestine contents and utilize acoustic signals detected during delivery of water into the large intestine and...
2017/0354688 THERAPEUTIC EFFECTS OF NURR1 AND FOXA2 IN INFLAMMATORY NEUROLOGIC DISORDERS BY M1-TO-M2 POLARIZATION OF GLIAL CELLS
A therapeutic effect of Nurr1 and Foxa2 in inflammatory neurologic disorders by M1-to-M2 polarization of glial cells is provided. Specifically, a method of...
2017/0354687 ISOLATED LIVER STEM CELLS
A method of treating liver-based inborn, metabolic deficiencies is disclosed by treatment of an individual, such as a patient suffering from liver-based...
2017/0354686 ADIPOSE DERIVED IMMUNOMODULATORY CELLS FOR IMMUNOTHERAPY OF RECURRENT SPONTANEOUS ABORTIONS
Disclosed are means of treating spontaneous abortion utilizing cellular populations derived from autologous adipose tissue. In one embodiment the invention...
2017/0354685 CELL-BASED COMPOSITION AND USE THEREOF FOR TREATMENT OF VERNAL KERATOCONJUNCTIVITIS
A method for the treatment of vernal keratoconjunctivitis in a subject by administering to said subject an effective amount of a cell-based composition...
2017/0354684 COMPOSITIONS FOR BIOLOGICAL SYSTEMS AND METHODS FOR PREPARING AND USING THE SAME
A method for performing a therapy in a subject includes providing a composition including a solution having a first volume and including a low pH fluid base...
2017/0354683 COMPOSITIONS FOR BIOLOGICAL SYSTEMS AND METHODS FOR PREPARING AND USING THE SAME
A composition for influencing biological growth includes a solution having a first volume and having low pH fluid base including dextrose, and albumin, wherein...
2017/0354682 Chimeric Protein
The present invention provides a chimeric protein having the formula: Casp-Ht1-Ht2 wherein Casp is a caspase domain; Ht1 is a first heterodimerization domain;...
2017/0354681 T CELL-BASED IMMUNOTHERAPEUTICS
The present invention provides compositions and methods for immunotherapy in human. The invention includes a B cell receptor like complex expressed in T cells...
2017/0354680 COMPOSITIONS CONTAINING ARSENIC AND THEIR USE IN METHODS OF TREATMENT
A pharmaceutical composition is provided comprising a highly soluble arsenic carbonate and/or bicarbonate compound and which is useful in the treatment of a...
2017/0354679 Mixture of processed salt and sugar in the manufacture of a medicament employed for treating Lax vegina...
The mixture of processed salt and sugar in the manufacture of a medicament employed for treating lax vagina syndrome or colpoxerosis disease in a mammal....
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