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Patent # | Description |
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2017/0354729 |
VACCINE COMPOSITIONS CONTAINING MODIFIED ZIKA VIRUS ANTIGENS The present disclosure relates to vaccine compositions that comprise a Zika virus antigen and an adjuvant. The present disclosure also provides methods for... |
2017/0354728 |
ANTIGEN SPECIFIC MULTI EPITOPE-BASED ANTI-INFECTIVE VACCINES The invention provides peptide vaccines comprising the signal peptide domain of selected target antigens of intracellular pathogens. The peptide vaccines of... |
2017/0354727 |
MODULATION OF REPLICATIVE FITNESS BY DEOPTIMIZATION OF SYNONYMOUS CODONS Methods of producing a pathogen with reduced replicative fitness are disclosed, as are attenuated pathogens produced using the methods. In particular examples,... |
2017/0354726 |
CANCER PEPTIDE VACCINE A composition for treating cancer, comprising 6 to 13 peptides derived from tumor antigens, wherein the composition is used in the manner that antibodies to... |
2017/0354725 |
COMBINATORIAL ANDROGEN DEPRIVATION WITH AN ANDROGEN RECEPTOR VACCINE It is disclosed herein methods of treating prostate cancer comprising administering to the subject the combination of androgen deprivation therapy (ADT) and a... |
2017/0354724 |
COMPOSITIONS AND METHODS FOR IMPROVED CAR-T CELL THERAPIES The present invention relates to the preparation and use in recipients of CAR-T cell-derived effector cells which are modified to limit their proliferation... |
2017/0354723 |
COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION The present invention relates to compositions and methods for cell transplantation. In particular, the present invention provides a composition with... |
2017/0354722 |
COMPOSITIONS AND METHODS FOR TREATING POST-OPERATIVE COMPLICATIONS OF
CARDIOPULMONARY SURGERY Compositions and methods for treating damage inflicted by use of a cardio-pulmonary bypass (CPB) machine, particularly excessive bleeding and multi organ... |
2017/0354721 |
WOUND HEALING COMPOUND The invention presented is an injectable wound healing compound that includes at least one antibiotic, a hemostatic agent, and an injectable flowable matrix.... |
2017/0354720 |
Novel Class of Therapeutic Protein Based Molecules The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides... |
2017/0354719 |
Compositions and Methods for Treating Pathological Calcification and
Ossification The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological... |
2017/0354718 |
FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in... |
2017/0354717 |
METHODS AND MEANS FOR DETERMINING TREATMENT OF SUBJECTS WITH EXOGENOUS
SOMATOTROPIN Described are methods for determining whether a subject has been treated with exogenous somatotropin. The disclosure further relates to kits for determining... |
2017/0354716 |
Novel Polymeric hGH Prodrugs The present invention relates to a polymeric human growth hormone prodrug and dry, liquid and reconstituted pharmaceutical formulations comprising said... |
2017/0354715 |
TREATMENT OF THROMBOCYTOPENIA USING ORALLY ADMINISTERED INTERFERON An interferon composition is provided for enhancing the platelet count, reducing the recurrence rate of hepatitis, and/or improving the social function of... |
2017/0354714 |
ANTI-OBESITY AND ANTI-DIABETIC EFFECTS OF ANGIOPOIETIN-LIKE 4 (ANGPTL4)
FIBRINOGEN-LIKE DOMAIN Angiopoietin-like 4 (Angpt14) is a secreted protein that inhibits lipoprotein lipase (LPL) activity and promotes lipolysis in adipocytes. The present methods... |
2017/0354713 |
FGF21 Derivatives and Uses Thereof The invention relates to a derivative of a FGF21 protein having a cysteine residue at a position corresponding to position 167, 169, 170, 171, 172, 173, 174,... |
2017/0354712 |
BPI AND ITS CONGENERS AS RADIATION MITIGATORS AND RADIATION PROTECTORS Described herein is a method of mitigating, in a subject (individual), tissue injury resulting from exposure to radiation (accidental/unintentional or... |
2017/0354711 |
HIGH DENSITY LIPOPROTEIN NANOPARTICLES FOR INFLAMMATION The invention in aspects relates to methods of treating sepsis using HDL-NP. The methods include the use of nanoparticles having a core and a lipid based shell... |
2017/0354710 |
METHODS OF USING GAP JUNCTIONS AS THERAPEUTIC TARGETS FOR THE TREATMENT OF
DEGENERATIVE DISORDERS OF THE RETINA The disclosure provides methods of treating a condition of the retina by administering an inhibitor of connexin 36 and/or an inhibitor of connexin 45 to a... |
2017/0354709 |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACUTE
EXACERBATIONS OF CHRONIC OBSTRUCTIVE... The present invention relates to methods and pharmaceutical compositions for the treatment of acute exacerbation of chronic obstructive pulmonary disease. In... |
2017/0354708 |
PEPTIDE CONGENERS WITH POLYMER EXCIPIENTS Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time... |
2017/0354707 |
CHEMICAL REPROGRAMMING OF HUMAN GLIAL CELLS INTO NEURONS FOR BRAIN AND
SPINAL CORD REPAIR Provided are methods and compositions from reprogramming human glial cells into human neurons. The reprogramming is achieved using combinations of compounds... |
2017/0354706 |
HYBRID PROTEINACEOUS MOLECULE CAPABLE OF INHIBITING AT LEAST ONE
ANTIBIOTIC AND PHARMACEUTICAL COMPOSITION... The invention relates to a hybrid proteinaceous molecule comprising at least two proteins capable of inhibiting the activity of at least one antibiotic, the... |
2017/0354705 |
HAND SANITIZER COMPOSITION AND METHOD OF MANUFACTURE A hand sanitizing composition and a method of manufacture, wherein the composition includes a solvent from about 78% to about 96% by weight sufficient to... |
2017/0354704 |
BIOLOGICALLY-ACTIVE TOMATO COMPOSITION HAVING REDUCED AMOUNT OF LYCOPENE The present invention provides a composition comprising lycopene, one or both of phytoene and phytofluene, and phytosterols, wherein the concentration of... |
2017/0354703 |
ANTI-GOUT COMPOSITION CONTAINING MIXED EXTRACT OF CHRYSANTHEMUM INDICUM
AND CINNAMOMUM CASSIA AS ACTIVE INGREDIENT An anti-gout composition including the mixed extract of Chrysanthemum indicum and Cinnamomum cassia as an active ingredient shows substantially greater... |
2017/0354702 |
DRUG CONTAINING THYME AND PRIMROSE OR THYME AND IVY AS A PDE-4 INHIBITOR The invention relates to an extract from thyme (Thymus L.) in combination with primrose (Primula veris) or ivy (Hedera helix) for use as PDE-4 inhibitor in the... |
2017/0354700 |
CHINESE MEDICINAL COMPOSITION FOR PREVENTING OR TREATING CARDIOVASCULAR
AND CEREBROVASCULAR DISEASES OR... Disclosed are a Chinese medicinal composition for preventing or treating cardiovascular and cerebrovascular diseases and/or dementia, and a preparation method... |
2017/0354699 |
EUGLENA LYSATE COMPOSITION A composition includes a Euglena lysate and cellular components and residual media remaining from a fermentation process that produced a Euglena biomass and... |
2017/0354698 |
METHOD OF PRODUCING A EUGLENA LYSATE A method for producing a Euglena lysate includes growing a biomass from genus Euglena organisms, dewatering the grown biomass, lysing the biomass, and drying... |
2017/0354697 |
TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTION Provided herein are compositions and methods for the treatment or prevention of pathogenic infections. |
2017/0354696 |
INFANT FORMULA WITH RRR-ALPHA-TOCOPHEROL, 2'-FUCOSYLLACTOSE, AND A
PROBIOTIC Infant formulas that include a combination of RRR-alpha-tocopherol, 2'-fucosyllactose, and at least one probiotic from the Lactobacillus or the Bifidobacterium... |
2017/0354695 |
COMPOSITIONS COMPRISING BACTERIAL STRAINS The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases. |
2017/0354694 |
KRILL OIL PREPARATIONS WITH OPTIMAL MINERAL AND METAL COMPOSITION, LOW
IMPURITIES AND LOW AND STABLE TMA LEVELS A Krill oil preparation including a reduced amount of trimethylamine of 5 mgN/100 g or less, or more than 700 ppm by weight of endogenous calcium and/or less... |
2017/0354693 |
CELL-BASED COMPOSITION AND USE THEREOF FOR TREATMENT OF MACULAR OEDEMA AND
DEGENERATION A method for the treatment of macular oedema and degeneration in a subject by administering to said subject an effective amount of a cell-based composition... |
2017/0354692 |
AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS Formulations of human amniotic fluid and methods of use thereof for treatment of lung disorders, and/or injuries have been developed. The formulations are... |
2017/0354691 |
CO-ENCAPSULATION OF LIVE CELLS WITH OXYGEN-GENERATING PARTICLES Microcapsules are described that comprise (a) a liquid aqueous or hydrogel core; (b) a semipermeable membrane surrounding said core; (c) live animal cells... |
2017/0354690 |
DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved... |
2017/0354689 |
SYSTEMS FOR CHARACTERIZATION OF THE CONTENTS OF THE LARGE INTESTINE AND
TREATMENT OF CONDITIONS OF THE LARGE... Systems are provided which analyze the large intestine contents and utilize acoustic signals detected during delivery of water into the large intestine and... |
2017/0354688 |
THERAPEUTIC EFFECTS OF NURR1 AND FOXA2 IN INFLAMMATORY NEUROLOGIC
DISORDERS BY M1-TO-M2 POLARIZATION OF GLIAL CELLS A therapeutic effect of Nurr1 and Foxa2 in inflammatory neurologic disorders by M1-to-M2 polarization of glial cells is provided. Specifically, a method of... |
2017/0354687 |
ISOLATED LIVER STEM CELLS A method of treating liver-based inborn, metabolic deficiencies is disclosed by treatment of an individual, such as a patient suffering from liver-based... |
2017/0354686 |
ADIPOSE DERIVED IMMUNOMODULATORY CELLS FOR IMMUNOTHERAPY OF RECURRENT
SPONTANEOUS ABORTIONS Disclosed are means of treating spontaneous abortion utilizing cellular populations derived from autologous adipose tissue. In one embodiment the invention... |
2017/0354685 |
CELL-BASED COMPOSITION AND USE THEREOF FOR TREATMENT OF VERNAL
KERATOCONJUNCTIVITIS A method for the treatment of vernal keratoconjunctivitis in a subject by administering to said subject an effective amount of a cell-based composition... |
2017/0354684 |
COMPOSITIONS FOR BIOLOGICAL SYSTEMS AND METHODS FOR PREPARING AND USING
THE SAME A method for performing a therapy in a subject includes providing a composition including a solution having a first volume and including a low pH fluid base... |
2017/0354683 |
COMPOSITIONS FOR BIOLOGICAL SYSTEMS AND METHODS FOR PREPARING AND USING
THE SAME A composition for influencing biological growth includes a solution having a first volume and having low pH fluid base including dextrose, and albumin, wherein... |
2017/0354682 |
Chimeric Protein The present invention provides a chimeric protein having the formula: Casp-Ht1-Ht2 wherein Casp is a caspase domain; Ht1 is a first heterodimerization domain;... |
2017/0354681 |
T CELL-BASED IMMUNOTHERAPEUTICS The present invention provides compositions and methods for immunotherapy in human. The invention includes a B cell receptor like complex expressed in T cells... |
2017/0354680 |
COMPOSITIONS CONTAINING ARSENIC AND THEIR USE IN METHODS OF TREATMENT A pharmaceutical composition is provided comprising a highly soluble arsenic carbonate and/or bicarbonate compound and which is useful in the treatment of a... |
2017/0354679 |
Mixture of processed salt and sugar in the manufacture of a medicament
employed for treating Lax vegina... The mixture of processed salt and sugar in the manufacture of a medicament employed for treating lax vagina syndrome or colpoxerosis disease in a mammal.... |