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Patent # Description
2017/0356045 GENES AND POLYMORPHISMS ASSOCIATED WITH AMD
There is provided a method of screening for susceptibility to complement dysregulation in an individual, the method including screening for the presence or...
2017/0356044 POLYMER CO-LOCATION IN SURFACE-ATTACHED BIOPOLYMERS AND ARRAYS OF BIOPOLYMERS
Embodiments of the present invention provide substrates having controllably co-located polymers of different sequences. Methods are provided that allow the...
2017/0356043 ACTIVITY-DEPENDENT GENE PAIRS AS THERAPEUTIC TARGETS AND METHODS AND DEVICES TO IDENTIFY THE SAME
Activity-dependent gene pairs as therapeutic targets and methods and devices to identify the same are provided. The methods and devices allow ...
2017/0356042 METHOD FOR HIGH-THROUGHPUT AFLP-BASED POLYMORPHISM DETECTION
The invention relates to a method for the high throughput discovery, detection and genotyping of one or more genetic markers in one or more samples, comprising...
2017/0356041 Methods and Compositions for Enriching Compositions for Polymerase Enzyme Complexes
The present invention provides methods, compositions, and systems for enriching compositions for polymerase enzyme complexes. In particular, the methods,...
2017/0356040 MANIPULATION OF MICROPARTICLES IN MICROFLUIDIC SYSTEMS
An array of transportable particle sets is used in a microfluidic device for performing chemical reactions in the microfluidic device. The microfluidic device...
2017/0356039 Vesicular linker and uses thereof in nucleic acid library construction and sequencing
Provided are a vesicular linker and a single-chain cyclic library constructed by using the linker. The library can be used for RNA sequencing and other...
2017/0356038 METHOD AND APPARATUS FOR THE ANALYSIS AND IDENTIFICATION OF MOLECULES
An apparatus and method for performing analysis and identification of molecules have been presented. In one embodiment, a portable molecule analyzer includes a...
2017/0356037 MUTANT PORES
The invention relates to mutant forms of Msp. The invention also relates to polynucleotide characterisation using Msp.
2017/0356036 METHODS AND DEVICES FOR DIGITAL PCR
Methods of conducting a nucleic acid reaction, including methods for performing digital PCR using a "droplet-in-oil" technology, may include at least partially...
2017/0356035 THREE-DIMENSIONAL POLYMER NETWORKS WITH CHANNELS SITUATED THEREIN
The disclosure provides three-dimensional crosslinked polymer networks comprising one or more channels extending from the surface and/or near the surface of...
2017/0356034 ASSAYS FOR RESISTANCE TO ECHINOCANDIN-CLASS DRUGS
Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate...
2017/0356033 CLAMPING PROBE
A method in which a mutant gene present in a gene pool mixedly with a large number of wild-type genes can be simply, inexpensively and sensitively detected is...
2017/0356031 COMPOSITIONS AND METHODS FOR THE DETECTION OF NUCLEIC ACIDS
The present invention provides methods for detecting a target nucleic acid in a sample by, for example, incubating the target nucleic acid with a detection...
2017/0356030 COMPOSITIONS, SYSTEMS, AND METHODS FOR DETECTING THE PRESENCE OF POLYMER SUBUNITS USING CHEMILUMINESCENCE
Under one aspect, a composition includes a substrate; a first polynucleotide coupled to the substrate; a second polynucleotide hybridized to the first...
2017/0356029 MICROBIOME MARKERS AND THERAPIES FOR AUTISM SPECTRUM DISORDERS
The present disclosure provides for characterization of normal flora and identifying biomarkers in the gut of healthy, neurotypical subjects. Aspect of the...
2017/0356028 BACTERIAL EPIGENOMIC ANALYSIS
Provided herein are systems and methods for determining the epigenetic sequences and signatures of bacteria, methods of characterizing bacteria based thereon,...
2017/0356027 CAPSULE ARRAY DEVICES AND METHODS OF USE
This disclosure provides microwell capsule array devices. The microwell capsule array devices are generally capable of performing one or more sample...
2017/0356026 Methods for RT-PCR comprising an anionic polymer
The present invention is directed to methods for the generation of nucleic acids from an RNA template and further nucleic acid replication. Specifically, the...
2017/0356025 INTERNAL CONTROL PROBES FOR IMPROVING PCR ASSAY PERFORMANCE
The present invention relates to methods for improving multiplex real-time PCR assays by the use of an internal control probe labeled with Quasar 705.
2017/0356024 BIOPHYSICAL PLATFORM FOR DRUG DEVELOPMENT BASED ON ENERGY LANDSCAPE
In one aspect, the present invention provides a method of selecting or identifying an agent that inhibits a target protein having an active site. In another...
2017/0356023 USE OF eRF1 MUTANTS IN UNNATURAL AMINO ACID INCORPORATION
The invention relates to a method for incorporating an unnatural amino acid into a protein of interest in a eukaryotic cell, said method comprising the steps...
2017/0356022 METHOD FOR STABILIZING PROTEINS
The present disclosure features methods and compositions for increasing the amount of products of cellular metabolism, e.g., proteins, by lowering the...
2017/0356021 Fiber-Containing Carbohydrate Composition
A food product comprises an oligosaccharide composition that is digestion resistant or slowly digestible. The oligosaccharide composition can be produced by a...
2017/0356020 METHOD OF FORMING A PURIFIED BETA-1,3,-GLUCAN
A method for producing a purified beta-1,3-glucan includes growing a biomass from genus Euglena organism and dewatering the grown biomass. The biomass is lysed...
2017/0356019 METHODS AND SYSTEMS USING FTIR FOR PLANT TRAIT DETECTION AND TRAIT INTROGRESSION
Provided are methods and/or systems having advantages of cost effective, time saving, and informative user-friendly characteristics to accomplish trait...
2017/0356018 METHOD OF MAKING LIPIDS WITH IMPROVED COLD FLOW PROPERTIES
Provided herein are methods of producing oils with reduced saturated fatty acids. The methods include culturing oil-producing microorganisms in a fermentation...
2017/0356017 TRANSFORMANT AND ITS PRODUCTION PROCESS, AND METHOD FOR PRODUCING LACTIC ACID
Provided is a transformant which can produce lactic acid with a high productivity without requiring neutralization with an alkali and is excellent in both of...
2017/0356016 MODIFIED MICROORGANISMS AND METHODS FOR PRODUCTION OF USEFUL PRODUCTS
Non-naturally occurring microbial organisms and related methods, processes and materials are for microbial organisms that include a genetic modification which...
2017/0356015 METHOD FOR PRETREATING WOOD DUST AND METHOD FOR MANUFACTURING BIOALCOHOL
A method for pretreating a wood dust includes conducting a structurally damaged step and an alkali treatment step. In the structurally damaged step, the wood...
2017/0356014 MULTI-ENZYME CONJUGATE, METHOD FOR PREPARING THE SAME AND METHOD FOR PREPARING ORGANIC COMPOUND USING THE SAME
The present disclosure relates to a multi-enzyme conjugate, a method for preparing the same and a method for preparing an organic compound using the same. More...
2017/0356013 Causative genes conferring acetic acid tolerance in yeast
The present invention relates to genes conferring acetic acid tolerance in yeast. More specifically, the invention relates to the use of DOT5, preferably in...
2017/0356012 FERMENTATION CONTROL FOR OPTIMIZATION OF SYNGAS UTILIZATION
Controlling the gas inlet flow rate and energy input to a fermentation reactor to maximize conversion of syngas by maximizing uptake of hydrogen into a medium...
2017/0356011 Delivery Across Cell Plasma Membranes
Delivering a payload across a plasma membrane of a cell includes providing a population of cells and contacting the population of cells with a volume of an...
2017/0356010 METHODS AND COMPOSITIONS FOR TRANSDUCING LYMPHOCYTES AND REGULATING THE ACTIVITY THEREOF
The present disclosure provides methods for genetically modifying lymphocytes and methods for performing adoptive cellular therapy that include transducing T...
2017/0356009 GENOME-MODIFIED RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS
Provided herein are recombinant adeno-associated virus (rAAV) nucleic acid vectors that comprise one or more modifications within at least one inverted...
2017/0356008 Further Improved AAV Vectors Produced in Insect Cells
The present invention relates to the production of adeno-associated viral vectors in insect cells. The insect cells therefore comprise a first nucleotide...
2017/0356007 EXPRESSION VECTORS COMPRISING CHIMERIC CYTOMEGALOVIRUS PROMOTER AND ENHANCER SEQUENCES
The present invention relates to expression vectors for the heterologous expression of a nucleic acid sequence of interest in mammalian cells, the vectors...
2017/0356006 OPTIMIZED EXPRESSION CASSETTE FOR EXPRESSING A POLYPEPTIDE WITH HIGH YIELD
The present invention is based on the finding that the combination of a specific 5'UTR polynucleotide sequence (see SEQ ID NO 1) and the hCD33 secretory leader...
2017/0356005 NON-VIRAL IPSCS INDUCING COMPOSITION AND KITS
The present invention relates to a non-viral iPSCs induction composition and the kits thereof. Specifically, it comprises a recombinant plasmid, and the...
2017/0356004 MULTIPLE VIRUS RESISTANCE IN PLANTS
The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present...
2017/0356003 METHOD FOR SCREENING OF GENES CONFERRING INCREASED TOLERANCE TO HERBICIDES
The present invention relates to a method for identifying a polynucleotide encoding a polypeptide which confers herbicide tolerance to a plant by measuring...
2017/0356002 METHODS FOR PROMOTING PLANT HEALTH USING FREE ENZYMES AND MICROORGANISMS THAT OVEREXPRESS ENZYMES
Methods for stimulating plant growth and/or promoting plant health using free enzymes or recombinant microorganisms that overexpress enzymes are provided....
2017/0356001 TRANSGENIC PLANTS WITH ENGINEERED REDOX SENSITIVE MODULATION OF PHOTOSYNTHETIC ANTENNA COMPLEX PIGMENTS AND...
Embodiments of the present invention provide for a transgenic plan, methods of making and DNA constructs for use in the transgenic plant which transgenic plant...
2017/0356000 METHODS FOR THE IMPROVEMENT OF PRODUCT YIELD AND PRODUCTION IN A MICROORGANISM THROUGH THE ADDITION OF...
The present invention provides for novel metabolic pathways to reduce or eliminate glycerol production and increase product formation. More specifically, the...
2017/0355999 METHODS AND COMPOSITIONS FOR REGULATION OF TRANSGENE EXPRESSION
Nucleases and methods of using these nucleases for expressing a transgene from a safe harbor locus in a secretory tissue, and clones and animals derived...
2017/0355998 Methods and Compositions for Treating Autoimmune Disorders by Targeting Kv1.3 Ion Channels with Functionalized...
Synthesis and pharmaceutical compositions of antibody-functionalized nanovesicles encapsulating ion channel knockout siRNA, and methods of treating autoimmune...
2017/0355997 METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS
The invention features therapeutic compositions comprising agents useful for the treatment or prevention of pruritis, and methods useful for identifying such...
2017/0355996 TREATMENT OF RNASE H1 RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO RNASE H1
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of RNase H1, in particular, by targeting natural...
2017/0355995 TREATMENT OF FIBROBLAST GROWTH FACTOR 21 (FGF21) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT...
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Fibroblast growth factor 21 (FGF21), in...
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