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| Patent # | Description |
|---|---|
| 2017/0369478 |
1,3-DIHYDROIMIDAZOLE-2-THIONE DERIVATIVES AS INHIBITORS OF
DOPAMINE-BETA-HYDROXYLASE Compounds of formula I and a method for their preparation are described, where R.sub.1, R.sub.2 and R.sub.3 are the same or different and signify hydrogens,... |
| 2017/0369477 |
1,3-Dihydroimidazole-2-Thione Derivatives for Use in the Treatment of
Pulmonary Arterial Hypertension and Lung... The present invention relates to compounds of formula I: ##STR00001## for use in treating pulmonary arterial hypertension and associated conditions, where... |
| 2017/0369476 |
2,4-DIAMINO-PYRIMIDINE COMPOUNDS AND METHOD FOR MAKING AND USING THE
COMPOUNDS Compounds within the scope of the present invention have a Formula 1 ##STR00001## or a salt or prodrug thereof, where ring A is selected from cycloaliphatic;... |
| 2017/0369475 |
Flibanserin Hydrate The present invention relates to a hydrate of flibanserin, a process for its preparation and to a pharmaceutical composition comprising the hydrate. The... |
| 2017/0369474 |
COMPOUNDS, COMPOSITIONS AND METHODS OF USE Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases,... |
| 2017/0369473 |
PYRROLIDINE DERIVATIVES AS ANGIOTENSIN II TYPE 2 ANTAGONISTS The invention relates to heterocyclic angiotensin II type 2 (AT.sub.2) receptor antagonists of formula (I), and pharmaceutically acceptable salts thereof, ((I)... |
| 2017/0369472 |
MAP KINASE MODULATORS AND USES THEREOF The invention provides for novel MAP kinase inhibitors and compositions comprising the same. In some embodiments, the MAP kinase inhibitors are p38.alpha. MAP... |
| 2017/0369471 |
5-SUBSTITUTED QUINAZOLINONE DERIVATIVES AND COMPOSITIONS COMPRISING AND
METHODS OF USING THE SAME Provided are 5-substituted quinazolinone compounds, for example, of formula (I), and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers,... |
| 2017/0369470 |
Cyclic Compounds and Uses Thereof The invention generally relates to substituted benzothiophenyl, substituted benzothiazolyl, substituted indolyl and substituted benzoimidazolyl compounds and,... |
| 2017/0369469 |
COMPOUNDS, COMPOSITIONS AND METHODS The disclosed subject matter provides certain polymorphic forms of Compound (I) as well as pharmaceutical compositions comprising Compound (I) or such... |
| 2017/0369468 |
ANTHROPOD REPELLENT CHEMICALS Compositions and methods for repelling arthropods. The compositions include a carrier and an arthropod repelling compound, which can be a compound discovered... |
| 2017/0369467 |
Process for the Preparation of N-Monosubstituted beta-Amino Alcohols A process is disclosed for the preparation of a compound of formula ##STR00001## and/or an addition salt of a proton acid, wherein R.sup.1 and R.sup.2 ... |
| 2017/0369466 |
3-[(BENZO[D][1,3]DIOXOLAN-4-YL)-OXY]-3-ARYLPROPYLAMINE TYPE COMPOUNDS AND
APPLICATIONS THEREOF The present invention relates to 3-[(benzo[d][1,3]dioxolan-4-yl)-oxy]-3-arylpropylamine compounds of formula I or pharmaceutically acceptable salts thereof and... |
| 2017/0369465 |
SOOTHING PRO-PHEROMONAL COMPOSITION FOR MAMMALS The invention relates to a compound of general formula (I) (in configuration Z or E) and to pro-pheromonal compositions and formulations comprising said... |
| 2017/0369464 |
Process for Producing 4-Azidosulfonylphthalic Anhydride The present disclosure provides a process for the production of 4-azidosulfonylphthalic anhydride. In an embodiment, a process is provided and includes... |
| 2017/0369463 |
ESTERIFICATION OF 2,5-FURAN-DICARBOXYLIC ACID A method of making a furan dicarboxylate by means of reacting 2,5-furan dicarboxylic acid (FDCA) with an alcohol or mixture of alcohols in a ... |
| 2017/0369462 |
Modulation of Bacterial Quorum Sensing with Synthetic Ligands The present invention provides compounds and methods for modulation of the quorum sensing of bacteria. In an embodiment, the compounds of the present invention... |
| 2017/0369461 |
PROFLAVOR DELIVERY POWDERS Provided herein are formulations of plated powders of acetaldehyde precursors. Also provided herein are methods of making and using the powders. |
| 2017/0369460 |
CARRIER TREATMENT TO IMPROVE CATALYTIC PERFORMANCE OF AN ETHYLENE OXIDE
CATALYST A method for lowering the sodium content of different carriers which may have different physical properties as well as varying degrees of sodium is provided.... |
| 2017/0369459 |
THIADIAZOLYL - OXIMINOACETIC ACID DERIVATIVE COMPOUNDS Thiadiazolyl-oximinoacetic acid derivatives have been synthesized, which are useful in the manufacture of cephalosporin antibiotic compounds. Compound (1)... |
| 2017/0369458 |
METHOD FOR PREVENTION OF PREMATURE POLYMERIZATION The present invention relates to a method for prevention of premature polymerization during the preparation, purification, transportation and storage of a... |
| 2017/0369457 |
Antibacterial Compounds The present invention relates to the following compounds for use in the treatment of a bacterial infection ##STR00001## wherein the integers are as defined in... |
| 2017/0369456 |
SYNTHESIS OF CYCLOPHANES FOR A SELF-ASSEMBLY REACTION Disclosed herein is a novel method for preparing cyclophanes, comprising forming a disulfide cyclophane by contacting a linker moiety which includes two or... |
| 2017/0369455 |
COMBINATION OF UV ABSORBER AND PIGMENT FOR PROTECTION OF SUBSTRATES FROM
UV/VIS-RADIATION A coating composition, which contains one or more compounds (A) according to formula (I) and a pigment (B) having a minimum integrated transmittance within the... |
| 2017/0369454 |
18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS The present technology is directed to compounds, intermediates thereof, compositions thereof, medicaments thereof, and methods related to the imaging of... |
| 2017/0369453 |
PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF The present disclosure relates generally to derivatives of pyrrolobenzodiazepines and antibody-drug conjugates thereof and to methods of using these conjugates... |
| 2017/0369452 |
Catalysis of Diketopiperazine Synthesis Provided is a method for the synthesis of N-protected bis-3,6-[4-aminobutyl]-2,5-diketopiperazine including the step of heating a solution of .epsilon.-amino... |
| 2017/0369451 |
METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES The present disclosure is directed to improved methods useful for the preparation of, for example, ... |
| 2017/0369450 |
ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials. |
| 2017/0369449 |
KINASE INHIBITORS FOR THE TREATMENT OF DISEASE The invention relates to compounds and their use in the treatment of disease. Novel irreversible inhibitors of wild-type and mutant forms of EGFR, FGFR, ALK,... |
| 2017/0369448 |
COMPOUNDS FOR AFFINITY CHROMATOGRAPHY AND FOR EXTENDING THE HALF-LIFE OF A
THERAPEUTIC AGENT Compounds useful for affinity chromatography as presented, more particularly for use in affinity chromatography to purify serum albumin, especially human serum... |
| 2017/0369447 |
COMPOUNDS USEFUL AS MODULATORS OF TRPM8 The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species... |
| 2017/0369446 |
MONOCYCLIC HETEROARYL COMPOUNDS This invention relates to compounds of the general formula: ##STR00001## in which the variable groups are as defined herein, and to their preparation and use. |
| 2017/0369445 |
a-KETOACYLIC ISONIAZID COMPOUNDS, PROCESS FOR PRODUCING SAID COMPOUNDS,
USE OF THE COMPOUNDS IN THE TREATMENT... The instant invention relates to compounds of formula I ##STR00001## wherein: R is selected from H, Me or Cl, and R' is selected from: H, NH.sub.2,... |
| 2017/0369444 |
INHIBITORS OF HISTONE DEMETHYLASES Compounds of the form in which Q is selected from --COOH--CH.dbd.NR.sup.12, --W, --CH.sub.2NHR.sup.13, --CH=0 and --CH(OR.sup.17).sub.2 capable of modulating... |
| 2017/0369443 |
FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF Described herein are compounds that are LOXL2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such... |
| 2017/0369442 |
METHOD FOR PREPARING 4-CYANOPIPERIDINE HYDROCHLORIDE The present invention describes a novel method for preparing 4-cyanopiperidine hydrochloride. |
| 2017/0369441 |
PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS Provided herein are compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat diseases or disorders... |
| 2017/0369440 |
PROCESS FOR THE PRODUCTION OF
2-[4-(CYCLOPROPANECARBONYL)PHENYL]-2-METHYL-PROPANENITRILE A new process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile is described. This compound can be used for the production of... |
| 2017/0369439 |
CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC
LIGHT-EMITTING DEVICE INCLUDING THE... A condensed cyclic compound represented by Formula 1: ##STR00001## wherein in Formula 1 groups and variables are the same as described in the specification. |
| 2017/0369438 |
METHOD FOR PRODUCING PYRROLE DERIVATIVE, AND INTERMEDIATE THEREOF The present invention provides a method for producing an atropisomer of a pyrrole derivative having excellent mineralocorticoid receptor antagonistic activity,... |
| 2017/0369437 |
Process for Preparing Alpha-Carboxamide Pyrrolidine Derivatives The invention relates to a novel process for preparing .alpha.-carboxamide pyrrolidine derivatives, in particular (2S, ... |
| 2017/0369436 |
METHODS FOR IMPROVED PRODUCTION OF VITAMINS D2 AND D3 It is an object of the present invention to provide methods for producing vitamin D that gives improved yields and reduced side product contamination. In... |
| 2017/0369435 |
COMPOUNDS FOR THE TREATMENT OF MTOR PATHWAY RELATED DISEASES The present invention relates to compounds for the treatment of mTOR (mammalian Target Of Rapamycin) pathway related diseases. Specifically, the present... |
| 2017/0369434 |
HYDROXY METHIONINE ANALOG FORMULATIONS SUITABLE FOR SPECIALTY CHEMICAL
APPLICATIONS Formulations comprising hydroxy methionine analog and having low levels of sulfate ions and bisulfate salts, processes for preparing the formulations,... |
| 2017/0369433 |
Beta Lactamase Inhibitors A compound which is a thienolate of formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein R.sup.1, R.sup.3, Ring A1, n and Ring A2 are as... |
| 2017/0369432 |
PREPOLYMERS EXHIBITING RAPID DEVELOPMENT OF PHYSICAL PROPERTIES Hydroxyl-containing bis(alkenyl) ethers can be incorporated into the backbone of polythioether prepolymers and can be used as curing agents in thiol-terminated... |
| 2017/0369431 |
HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE The present disclosure is directed dye compounds containing a hydrazinyl substituent and optionally, one or more negatively charged groups, such as sulfonate,... |
| 2017/0369430 |
OXYGENATED AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID
AND CARBOXYLIC ACID DERIVATIVES AND... The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphoric acid and carboxylic acid derivatives, in particular the... |
| 2017/0369429 |
METHOD FOR PREPARING HIGH-PURITY SULFONAMIDE COMPOUND, AND INTERMEDIATE OF
SULFONAMIDE COMPOUND The present invention discloses a method for preparing a high-purity sulfonamide compound and an intermediate of the sulfonamide compound. The method comprises... |
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