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Patent # Description
2017/0368212 ANTI-BACTERIAL LIGHT DELIVERY SYSTEM AND METHOD FOR DISINFECTING A SURFACE
A light delivery system and method are provided to promote a photochemical reaction for disinfecting a surface. The system includes a light source and a light...
2017/0368211 HEAT TREATMENT OF A NANOFIBRILLAR CELLULOSE HYDROGEL
The invention relates to a method for treating a nanofibrillar cellulose hydrogel, wherein the method comprises the steps of: providing a nanofibrillar...
2017/0368210 BACTERICIDAL LIGHT SOURCE WITH HIGH QUALITY OF LIGHT
A light source for emitting emitted light having an SPD comprising: (a) a plurality of light emitters including at least one violet solid-state emitter; (b) at...
2017/0368209 POSITRON EMISSION CAPSULE FOR IMAGE-GUIDED PROTON THERAPY
Multi-modal imaging capsule for image-guided proton beam therapy, consisting of a biocompatible polymer layer, .sup.18O-enriched water, and a contrast agent....
2017/0368208 CANCER IMAGING AGENT
The present disclosure relates to imaging agent formulations, methods for preparing imaging agent formulations and methods for using the same. The present...
2017/0368207 SELF-ASSEMBLED NANOSTRUCTURE AND METHOD FOR PREPARING THE SAME
A self-assembled nanostructure including an amphiphilic chitosan and a contrast agent compound is provided. The contrast agent compound is grafted to the...
2017/0368206 CURABLE COMPOSITION AND METHOD FOR IMPLANTATION
A biocompatible curable composition and a method of detecting a border of a tumor, a tissue of interest, or both including injecting the biocompatible curable...
2017/0368205 SYSTEM AND METHOD FOR ENHANCED MASS SPECTROMETRY IMAGING
Various embodiments are described herein for a system and a method for identifying a region of interest in tissue using mass spectrometry. An agent...
2017/0368204 POLYMER MICROBUBBLES AS X-RAY DARK FIELD CONTRAST AGENTS
The present invention discloses compositions and methods for clinical imaging. In particular, these compositions and methods provide improvements to...
2017/0368203 Compositions For Enhancing Transport Of Molecules Into Cells
Compositions and methods for enhancing delivery of molecules, e.g. biological agents, into cells are described. The composition is a conjugate of the...
2017/0368202 OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO
The present invention provides methods and compositions based on optical sensor conjugates that are useful for detecting reactive oxygen, reactive nitrogen, or...
2017/0368201 SCALABLE MANUFACTURING PROCESS TO PRODUCE RECOMBINANT LENTIVIRAL VECTORS IN SERUM-FREE SUSPENSION CELL CULTURE...
Methods for preparing highly purified rLV vector formulations at the scale needed to meet anticipated demand for human gene therapy are provided.
2017/0368200 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA...
2017/0368199 Methods and Compositions for Treating Dystroglycanopathy Disorders
The invention relates to synthetic polynucleotides encoding fukutin related protein (FKRP). The invention further relates to nucleic acid constructs comprising...
2017/0368198 OPTIMIZED MINI-DYSTROPHIN GENES AND EXPRESSION CASSETTES AND THEIR USE
This invention relates to polynucleotides encoding mini-dystrophin proteins, viral vectors comprising the same, and methods of using the same for delivery of...
2017/0368197 Pharmaceutical Composition Comprising Amorphous Lenalidomide
The present invention relates to a pharmaceutical composition comprising an inclusion complex of amorphous lenalidomide, or a pharmaceutically acceptable salt...
2017/0368196 BI-FUNCTIONAL ALLOSTERIC PROTEIN-DRUG MOLECULES FOR TARGETED THERAPY
Disclosed herein, is a bi-functional allosteric protein-drug molecule comprising a targeting moiety, one or more biological binding domains, and one or more...
2017/0368195 ANTI-DLL3 ANTIBODY DRUG CONJUGATES
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
2017/0368194 CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
Provided are methods relating to the use of CDP-therapeutic agent conjugates for the treatment of a disease or disorder, e.g., autoimmune disease, inflammatory...
2017/0368193 NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE
The invention relates to materials and methods of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein comprising...
2017/0368192 LUMINAL VESSEL COATING FOR ARTERIOVENOUS FISTULA
This disclosure provides a method for improving maturation of an arteriovenous fistula (AVF) in a patient in need of hemodialysis, which method entails...
2017/0368191 LOW MOLECULAR WEIGHT POLYETHYLENE GLYCOL DRUG CONJUGATES HAVING IMPROVED DRUG BIOLOGICAL ACTIVITY
Provided are polyethylene glycol drug conjugates of general formula (I), (II) or (III) and pharmaceutical compositions and a use thereof. The conjugates are...
2017/0368190 Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same
The present invention relates, in part, to a biocompatible hydrophobic-core carrier comprising a carrier, and a plurality of hydrophobic groups covalently...
2017/0368189 CNP PRODRUGS
The present invention relates to prodrugs of C-type natriuretic peptide (CNP), pharmaceutical compositions comprising such CNP prodrugs and their uses. In an...
2017/0368188 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS
The invention relates to novel compounds for use in the treatment or prophylaxis of cancers and other proliferative conditions that are for example...
2017/0368187 GLYCEROPHOSPHOLIPIDS FOR THE IMPROVEMENT OF COGNITIVE FUNCTIONS
The invention described herein provides a preparation comprising a non-mammalian derived mixture of serine glycerophospholipid conjugates with a specific...
2017/0368186 JASMONATE DERIVATIVES AND COMPOSITIONS THEREOF
The disclosure describes jasmonate conjugates and nanocarried and/or microcarried jasmonate conjugates and pharmaceutical compositions thereof, as well as use...
2017/0368185 METHOD OF PREPARING DENDRITIC DRUGS
Synthetic design of drug-incorporated novel dendrimer structures for quantitatively controlled drug delivery. The dendritic drugs have better control and thus...
2017/0368184 SELF-EMULSIFYING COMPOSITION OF OMEGA-3 FATTY ACID
A self-emulsifying composition contains: 70 to 90% by weight of at least one compound selected from the group consisting of .omega.3 polyunsaturated fatty...
2017/0368183 TISSUE REPAIR SYSTEM
An implant for promoting accelerated wound healing. The implant comprises a non-flocculating fiber material, admixed with a settable fluid. The fiber component...
2017/0368182 Pharmaceutical Semi-Solid Gels with Entrapped Calcium Phosphate Nanoparticles
The present disclose generally provides pharmaceutical semi-solid hydrogels with entrapped calcium phosphate Comparison of Fitted Curves with Log Time for...
2017/0368181 Polymeric Nanoparticle
In a first aspect, the invention provides a polymeric nanoparticle comprising at least one polycationic polymer; at least one polyanionic polymer; and a...
2017/0368180 METHODS OF PROMOTING NERVOUS SYSTEM REGENERATION
The invention includes a composition comprising an astrocyte comprising aligned and elongated astrocyte processes resulting from ex vivo machine-driven,...
2017/0368179 SILICONE ACRYLATE COMPOSITIONS AND METHODS OF PREPARING THE SAME
Silicone acrylate copolymer composition, namely, silicone resin-acrylate copolymers and methods of preparing the same. The silicone acrylate composition may...
2017/0368178 ADSORPTION OF FLUORINATED ANESTHETICS WITHIN THE PORES OF MOLECULAR CRYSTALS
A method of delivering or sequestering anesthetic agents by adsorption of such agents by porous partially fluorinated compounds which display high weight...
2017/0368177 NOVEL PEG DERIVATIVE
Provided is a new therapeutic agent for a malignant tumor, which is highly safe, sustains an antitumor effect, and can improve the means for administration and...
2017/0368176 NON-TOXIC TOPICAL ANESTHETIC OPHTHALMIC COMPOSITIONS
Compositions and methods for prolonging the local anesthetic effect of site 1 sodium channel blockers and local anesthetics with minimal or reduced toxicity...
2017/0368175 PHARMACEUTICAL FORMULATION COMPRISING ANTI-EGFR ANTIBODY
The present invention provides a pharmaceutical formulation comprising an anti-epidermal growth factor receptor (EGFR) antibody. The pharmaceutical formulation...
2017/0368174 PHARMACEUTICAL PRODUCTS AND STABLE LIQUID COMPOSITIONS OF IL-17 ANTIBODIES
The disclosure is directed to pharmaceutical products and stable liquid compositions of IL-17 antibodies and antigen-binding fragments thereof, e.g., AIN457...
2017/0368173 CANCER TREATMENT COMBINATIONS
There are provided, inter alia, compositions and methods for treatment of cancer. The methods include administering to a subject in need a therapeutically...
2017/0368172 USE OF ANTI-PD-1 ANTIBODY IN COMBINATION WITH ANTI-CD27 ANTIBODY IN CANCER TREATMENT
This disclosure provides methods for treating cancer in a subject comprising administering to the subject an anti-PD-1 antibody and an anti-CD27 antibody. In...
2017/0368171 Diagnostics and Therapeutics for Diseases Associated With G-Protein Coupled Receptor AdipoR2 (AdipoR2)
The invention provides human AdipoR2 which is associated with the cardiovascular diseases, dermatological diseases, gastroenterological diseases, cancer,...
2017/0368170 SELF-BUFFERING PROTEIN FORMULATIONS
The invention herein described, provides, among other things, self-buffering protein formulations. Particularly, the invention provides self-buffering...
2017/0368169 MULTISPECIFIC AND MULTIFUNCTIONAL MOLECULES AND USES THEREOF
Multispecific molecules that include i) a tumor-targeting moiety; and one, two or all of: (ii) an immune cell engager (e.g., chosen from an NK cell engager, a...
2017/0368168 ANTI-TIM-3 ANTIBODIES AND METHODS OF USE THEREOF
The instant disclosure provides antibodies that specifically bind to TIM-3 (e.g., human TIM-3) and antagonize TIM-3 function. Also provided are pharmaceutical...
2017/0368167 COMPOSITIONS AND METHODS RELATED TO NEUROLOGICAL DISORDERS
The present technology relates to compositions comprising inulin particles for use in the enhancement of immune responses to neuronal self-antigens for...
2017/0368166 Tissue Targeted Antigenic Activation of the Immune Response to Treat Cancers
The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one...
2017/0368165 RECOMBINANT INFLUENZA VIRUS VACCINES FOR INFLUENZA AND RESPIRATORY SYNCYTIAL VIRUS
Disclosed are recombinant chimeric influenza virus vaccines and live attenuated influenza virus (LAIV) vaccines expressing foreign (RSV) neutralizing epitopes...
2017/0368164 SYNERGISTIC CO-ADMINISTRATION OF COMPUTATIONALLY OPTIMIZED BROADLY REACTIVE ANTIGENS FOR H1N1 INFLUENZA
The present invention provides co-administration (for example, immunogenic cocktail compositions and/or prime-boost regimens) of computationally optimized H1N1...
2017/0368163 METHODS AND COMPOSITIONS FOR INHIBITING POLYOMAVIRUS-ASSOCIATED PATHOLOGY
Disclosed herein are methods of eliciting an immune response against a polyomavirus (for example, BKV serotype I (BKV-I), BKV serotype II (BKV-II), BKV...
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