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Patent # Description
2017/0368060 Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders
The present invention provides a heterocyclic compound represented by the general formula (1): The compound of the present invention has a wide treatment...
2017/0368059 USE OF LEVOCETIRIZINE AND MONTELUKAST IN THE TREATMENT OF ANAPHYLAXIS
The embodiments described herein include methods and formulations for treating anaphylaxis and related acute allergic reactions. The methods and formulations...
2017/0368058 POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE
The invention provides compositions and methods for the treatment or prevention of pain. The invention provides constructs whereby hydrolysis of the construct...
2017/0368057 PROCESS OF MAKING STABLE ABUSE-DETERRENT ORAL FORMULATIONS
The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to...
2017/0368056 METHODS FOR TREATING PANCREATIC CANCER USING COMBINATION THERAPIES COMPRISING LIPOSOMAL IRINOTECAN
Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional...
2017/0368055 METHODS FOR TREATING INFECTIONS
The present invention relates to methods for treating, preventing, or reducing the risk of microbial infections while minimizing adverse gastrointestinal...
2017/0368054 Treatment of Glaucoma Using Laquinimod
The subject invention provides a method of treating a subject afflicted with glaucoma, suffering from retinal ganglion cell (RGC) loss or damage, or elevated...
2017/0368053 TREATMENT OF LUPUS NEPHRITIS USING LAQUINIMOD
This invention provides a method of treating a subject afflicted with active lupus nephritis comprising periodically administering to the subject an amount of...
2017/0368052 CRYSTAL FORMS OF APOMORPHINE AND USES THEREOF
The present invention provides solid crystalline forms of apomorphine free base or a hydrate, solvate, or co-crystals thereof. Such crystalline forms may be...
2017/0368051 2-PHENETHENYLTETRAHYDRO ISOQUINOLINES USEFUL AS ANTI-HIV COMPOUNDS
This invention provides, among other things, tetrahydroisoquinolines useful for treating viral infections, pharmaceutical formulations containing such...
2017/0368050 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MAST CELL-INDUCED VASCULAR LEAKAGE
Disclosed herein are methods of diagnosing and treating infectious disease characterized by a pathology that involves hemorrhaging or pathological vascular...
2017/0368049 COMPOSITE CAPSULES COMPRISING RALOXIFENE, AND VITAMIN D OR ITS DERIVATIVES
A composite capsule and a method of preparing the same are provided. The composite capsule includes: a raloxifene separate layer including raloxifene or a...
2017/0368048 Pharmaceutical Composition Comprising Amorphous Lenalidomide
The present invention relates to a pharmaceutical composition comprising an amorphous adsorbate of lenalidomide, or a pharmaceutically acceptable salt thereof,...
2017/0368047 Immunomodulation by IAP Inhibitors
The present invention is directed to immune adjuvants containing IAP inhibitors, including Smac mimetics. The invention further provides pharmaceutical...
2017/0368046 COMPOSITIONS AND METHODS FOR TREATING PELVIC PAIN AND OTHER CONDITIONS
Methods are provided for treating conditions including chronic pelvic pain, in which there are palpable trigger points of local areas of muscle restriction and...
2017/0368045 COMPOSITIONS, METHODS, AND KITS FOR REGULATING METABOLISM
The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that...
2017/0368044 PIM KINASE INHIBITOR COMBINATIONS
The present invention relates to a Pim kinase inhibitor compound that can be used alone or in a pharmaceutical combination. One such combination comprises (a)...
2017/0368043 METHOD OF TREATING PANCREATIC CANCER
The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or...
2017/0368042 Dosage Suspensions Of Active Pharmaceutical Ingredients
Methods for preparing suspensions of active pharmaceutical ingredients for ensuing drug delivery. The suspension may include a mixture of a relatively low...
2017/0368041 METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OX- ...
Methods of treating, preventing or managing antecedent hematologic disorders, such as myelodysplastic syndrome, including chronic myelomonocytic leukemia are...
2017/0368040 Processes for Preparing Dolutegravir and Cabotegravir and Analogues Thereof
The present invention relates to processes for preparing substances with antiviral activity, in particular the integrase inhibitors dolutegravir and...
2017/0368039 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound...
2017/0368038 AZABICYCLOOCTANE DERIVATIVES AS FXR AGONISTS FOR USE IN THE TREATMENT OF LIVER AND GASTROINTESTINAL DISEASES
The invention provides methods for modulating the activity of farnesoid X receptors (FXRs) using compounds of Formula (I) or (II). In particular, the invention...
2017/0368037 PHARMACEUTICAL COMPOSITION FOR PROMOTION OF FIBRINOLYSIS
It is intended to provide a novel pharmaceutical composition that can promote fibrinolysis. The present invention provides a pharmaceutical composition for the...
2017/0368036 AR+ BREAST CANCER TREATMENT METHODS
A method for treating AR+ breast cancer in a subject comprising administering to the subject an AR agonist (e.g., SARMs such as RAD140), or in combination with...
2017/0368035 5,5-Bicyclic Oxazole Orexin Receptor Antagonists
The present invention is directed to 5,5-bicyclic oxazole compounds which are antagonists of orexin receptors. The present invention is also directed to uses...
2017/0368034 THIOTRIAZOLE COMPOUND AND ITS USE IN PARASITIC PROTOZOAL INFECTIONS
The present invention relates to a compound of Formula (I) or tautomers thereof having pharmacological activity, processes for its preparation, pharmaceutical...
2017/0368033 AFFINITY BASED DRUG RELEASE FORMULATIONS
The present application describes a two-step drug delivery formulation comprising a high affinity interaction between a drug conjugate and a compound, followed...
2017/0368032 Imidazole-Based Antimicrobial Agents
The present invention relates to novel therapeutic agents suitable for use in the treatment of mammalian disease and in particular to novel therapeutic agents...
2017/0368031 SOLID DISPERSION FORMULATIONS OF ANTIVIRAL COMPOUNDS
The present disclosure is directed to solid dispersion formulations comprising an NS5A inhibitor compound, elbasvir (dimethyl N,N'-([(6S)-6-phenylindolo [1,2-...
2017/0368030 Dihydropyrazoles
Novel dihydropyrazole derivatives of formula (I) ##STR00001## wherein L, R, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, X.sup.1, X.sup.2, X.sup.3, X.sup.4, Y, m...
2017/0368029 N-METHYL-N-(1-PHENYL-2-(1-PYRROLIDINYL)ETHYL)-2-AMINOPHENYLACETAMIDE DERIVATIVES AGONISTS FOR THE KAPPA OPIOID...
Compounds and pharmaceutically acceptable salts and solvates thereof are described. The compounds relate to and/or have application(s) in (among others) the...
2017/0368028 N-BENZOATE GROUP SUBSTITUTED BENZOPYRROLINE-2-ONE DERIVATIVE AND USE THEREOF
Disclosed are a compound, a stereisomer and a tautomer thereof, a pharmaceutically acceptable salt thereof, and a solvate or a prodrug thereof, which can be...
2017/0368027 NUTRITIONAL COMPOSITION USEFUL IN THE TREATMENT OF IBD PATIENTS
Compositions and methods are provided that are useful in the treatment of inflammatory bowel disease (IBD) patients. The Compositions and methods are suitable...
2017/0368026 PROMOTION OF HEALING OF INTESTINAL MUCOSA USING PROLINE, SERINE AND THREONINE
Methods and compositions are provided that use proline, serine and threonine to promote healing of the intestinal mucosa. A therapeutically effective amount of...
2017/0368025 COMBINATION OF CANAGLIFLOZIN AND PROBENECID FOR THE TREAMENT OF HYPERURICEMIA
The present invention is directed to methods for treating hyperuricemia and related disorders, comprising co-therapy with canagliflozin and probenecid.
2017/0368024 Compositions and Methods for Treating Glaucoma
Compositions and methods for treating glaucoma by restoring the filtration capabilities of the endothelial lining of Schlemm's canal are provided. More...
2017/0368023 SUBLINGUAL SPRAY FORMULATION COMPRISING DIHYDROARTEMESININ
The invention provides pharmaceutical compositions for the treatment of neoplastic diseases, fluke infestations and Lyme disease, comprising compounds capable...
2017/0368022 LIQUID CARBON DIOXIDE BOTANICAL EXTRACTION SYSTEM
A process is disclosed for extracting cannabinoids from plant materials. The process comprises providing a pressurizable extraction vessel having a rotatable...
2017/0368021 MEDICATED PRODUCE
Methods and products of processes result in novel medicated food items including produce items. Cannabinoids from marijuana plants, including THC, CBD and CBC...
2017/0368020 Oral compositions delivering therapeutically effective amounts of cannabinoids
Oral compositions provide delivery of cannabinoids to a subject. The oral compare chewable, fast- or slow-dissolving once placed in the mouth of a subject.
2017/0368019 CRYSTAL FORMS OF SCUTELLARIN AGLYCONE AND PREPARATION THEREOF
The invention belongs to the field of medicine and chemical industry, and particularly relates to multiple crystal forms of scutellarin aglycone and...
2017/0368018 USE OF ELLAGIC ACID DIHYDRATE IN PHARMACEUTICAL FORMULATIONS TO REGULATE BLOOD GLUCOSE LEVELS
The present invention relates generally to pharmaceutical compositions and methods of use that include an ellagic acid dihydrate compound that assists in...
2017/0368017 ANTIBACTERIAL COMPOUNDS
The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
2017/0368016 METHOD FOR REVERSING, PREVENTING, DELAYING OR STABILIZING SOFT TISSUE CALCIFICATION
The present invention provides methods of treating soft tissue calcification in a subject, comprising a step of administering to said subject an effective...
2017/0368015 NOVEL COMPOUND AND ANTIVIRAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT
An object of the invention is to provide a compound that can be utilized as an antiviral agent, in particular as an anti-RNA viral agent, and especially as an...
2017/0368014 CRYSTALLINE FORMS OF (N, N-DIETHYLCARBAMOYL)METHYL METHYL (2E)BUT-2-ENE-1,4-DIOATE, METHODS OF SYNTHESIS AND USE
Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate....
2017/0368013 Methods of Treating Multiple Sclerosis
Provided herein are methods of treating multiple sclerosis with a fumarate, wherein the fumarate is a dialkyl fumarate, a monoalkyl fumarate, a combination of...
2017/0368012 COMPOSITIONS, METHOD, AND KITS FOR TREATING PULMONARY CONDITIONS
Compositions, methods, and kits useful for treating pulmonary conditions are provided herein. Such compositions can contain synergizing amounts of a...
2017/0368011 ISOPRENYL COMPOUNDS AND METHODS THEREOF
Among other things, the present invention provides novel isoprenyl compounds capable of effectively modulating inflammatory responses and pharmaceutical,...
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