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Patent # Description
2017/0368010 NEPRILYSIN INHIBITORS
In one aspect, the invention relates to compounds having the formula: ##STR00001## where R.sup.1-R.sup.6, a, b, and Z are as defined in the specification, or a...
2017/0368009 METHOD FOR THE PREPARATION OF N-ACETYL CYSTEINE AMIDE
The present application discloses an efficient process for the preparation of N-acetyl-L-cysteine amide (NACA) starting with N-acetyl-L-cysteine.
2017/0368008 BOLUS DOSE OF HYDROXYCITRIC ACID WITH GLYCEROL
A method of delivering a daily dose of hydroxycitric acid in the form of a salt as a single bolus that is as effective or more so than the same amount of...
2017/0368007 USE OF 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES FOR TREATING LIVER DISORDERS
The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular...
2017/0368006 USE OF TAURINE IN PREVENTION AND/OR TREATMENT OF DISEASES INDUCED BY VIRUSES OF GENUS CORONAVIRUS AND/OR GENUS...
The present invention provides use of taurine in prevention and/or treatment of diseases induced by viruses of genus coronavirus and/or genus rotavirus, for...
2017/0368005 DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL
The present technology is directed to compounds, compositions, medicaments, and methods related to the treatment of cancers expressing PSMA. The compounds are...
2017/0368004 COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID...
The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart...
2017/0368003 SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF
This invention is directed to pyrrole, pyrazole, imidazole, triazole, and morpholine based selective androgen receptor degrader (SARD) compounds including...
2017/0368002 INKT CELL MODULATORS AND METHODS OF USING THE SAME
Disclosed herein are .alpha.-galactosylceramide (.alpha.-GalCer) analogs and compositions thereof, methods of activating invariant Natural Killer T (iNKT)...
2017/0368001 Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P...
2017/0368000 Intranasal Formulation of Epinephrine for the Treatment of Anaphylaxis
This invention relates to pharmaceutical compositions of epinephrine for delivery to the nasal mucosa and methods of treating a subject in acute severe...
2017/0367999 TOPICAL DAPSONE AND DAPSONE/ADAPALENE COMPOSITIONS AND METHODS FOR USE THEREOF
Dapsone and dapsone/adapalene compositions can be useful for treating a variety of dermatological conditions. The compositions of this disclosure include...
2017/0367998 SMALL MOLECULE THERAPEUTIC COMPOUNDS TARGETING THIOESTERASE DEFICIENCY DISORDERS AND METHODS OF USING THE SAME
The invention provides methods of inhibiting the development or progression of a thioesterase deficiency disorder in a mammal by the administration of a...
2017/0367997 THERAPEUTIC AGENT FOR CANCER
To provide a therapeutic agent for cancer having a higher therapeutic effect. A therapeutic agent for cancer, containing: at least one selected from the group...
2017/0367996 Use Of Xanthophyll Carotenoids To Improve Visual Performance And Neural Efficiency
In one embodiment, the invention provides a method of enhancing a subject's macular pigment optical density, the method comprising administering to the subject...
2017/0367995 TREATMENT OF EARLY STAGE PARKINSON'S DISEASE WITH A HYDROXYTYROSOL-CONTAINING POLYPHENOL FORMULATION
The invention provides a method for treating a subject suffering from early stage Parkinson's disease with a pharmaceutical formulation containing an olive...
2017/0367994 TRANSDERMAL PREPARATION
The present invention provides transdermal absorption preparation having a support, and a drug-containing adhesive layer formed on the support, wherein a...
2017/0367993 FILM PREPARATION
The present invention addresses the problem of providing a film preparation that enables large quantities of medicinal products to be blended thereinto. The...
2017/0367992 DRUG DELIVERY SYSTEM FOR DELIVERY OF ACID SENSITIVITY DRUGS
The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which...
2017/0367991 TISSUE THICKNESS COMPENSATOR CONFIGURED TO REDISTRIBUTE COMPRESSIVE FORCES
A tissue thickness compensator may generally comprise a compressible core comprising a plurality of movable particles, and a wrap surrounding the compressible...
2017/0367990 USE OF NANOPARTICLES COATED WITH RED BLOOD CELL MEMBRANES TO ENABLE BLOOD TRANSFUSION
The present invention relates to methods, combinations and pharmaceutical compositions for supplying a blood source from a donor source with a mis-matched...
2017/0367989 NANOPARTICLES FOR LIPID HOMEOSTASIS
Nanoparticles include a polymeric core and a high density lipoprotein (HDL) component where the ratio by weight of the HDL component to the polymeric core is...
2017/0367988 LIPID NANOPARTICLES COMPRISING LIPOPHILIC ANTI-INFLAMMATORY AGENTS AND METHODS OF USE THEREOF
Disclosed herein are lipid nanoparticles comprising a lipid phase and at least one lipophilic anti-inflammatory agent, and pharmaceutical compositions...
2017/0367987 Formulations and Methods for Attenuating Respiratory Depression Induced by Opioid Overdose
The invention relates to compositions and methods for attenuating opioid induced respiratory depression. Such compositions comprise opioids and sequestered...
2017/0367986 CONTROLLED RELEASE FROM PARTICLES ENCAPSULATED BY MOLECULAR LAYER DEPOSITION
The invention provides a slow-release material comprising particles, wherein the particles comprise a core comprising an active component and a multilayer...
2017/0367985 Enteric Film Coating Compositions, Method of Coating, and Coated Forms
A food safe, plant based, water soluble, dry powder formulation and an aqueous enteric coating solution made therefrom, that is used for providing an enteric...
2017/0367984 CONTROLLED RELEASE OF CAFFEINE
The present invention relates to an edible composition having a lipid continuous phase and self-assembled structures, the composition comprising oil,...
2017/0367982 HIGH DENSITY LIPOPROTEIN FUNCTIONALIZED MAGNETIC NANOSTRUCTURES
Provided herein are compositions and methods for diagnosis and treatment of early-stage atherosclerotic plaques and reduction of plaques in arteries. In...
2017/0367981 BIOMIMETIC DRUG DELIVERY OF AN IMMUNOMODULATORY AGENT FOR THE TREATMENT OF OCULAR CONDITIONS
A method for treating an ocular disorder in a subject comprising administering a therapeutic agent-loaded carrier to an ocular site of the subject in need...
2017/0367980 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY
Nano-sized particles are provided comprising at least one multi-headed amphiphilic compound, in which at least one headgroup of said multi-headed amphiphilic...
2017/0367979 METHODS OF TREATING ARTHRITIS
The present invention provides methods of treating arthritis. A sustained release composition comprising liposomes and one or more therapeutic agent or a...
2017/0367978 AQUEOUS TOPICAL DRUG FORMULATION WITH CONTROLLED RELEASE AND INCREASED STABILITY
This invention provides a topical drug formulation and methods for the preparation thereof. This invention further provides the use of said drug formulation in...
2017/0367977 AQUEOUS COMPOSITION
A technique is provided for reducing the discoloration of an aqueous composition containing a halogenated isoquinoline derivative during high-temperature...
2017/0367976 Pharmaceutical Capsules For Medication Adherence Monitoring And Methods Of Forming The Same
Provided according to embodiments of the invention pharmaceutical capsules that include a capsule body and a capsule cap, wherein the capsule cap envelops an...
2017/0367975 PHARMACEUTICAL TABLET FOR USE IN ADMINISTERING ONE OR MORE PHARMACEUTICALLY ACTIVE INGREDIENTS
A pharmaceutical tablet for use in administering one or more pharmaceutically active ingredients, comprising a polymer system, the one or more pharmaceutically...
2017/0367974 Polymer Implants For Treatment Of Metabolic Disorders
Implantable devices including a biocompatible matrix configured for long term location in adipose tissue and a biologically active agent that can be carried by...
2017/0367973 COMPOSITIONS COMPRISING MACROMOLECULAR ASSEMBLIES OF LIPID AND SURFACTANT
A composition comprising lipid and surfactant, characterised in that the surfactant has an HLB number of less than 20 and in that the lipid and surfactant are...
2017/0367972 Formulations and Methods of Treatment for Treating Nail Fungal Infections
The present invention relates to methods and compositions for the treatment of infections of the nails, in particular the treatment of onychomycosis.
2017/0367971 NOVEL PROPELLANT CONTAINING PREPARATIONS FOR TIOTROPIUM
The present invention relates to a novel propellant-gas-containing medicament composition based on tiotropium 1, processes for the preparation thereof and the...
2017/0367970 ALLERGEN DOSAGE FORM
The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, ...
2017/0367969 PALONOSETRON ORAL TRANSMUCOSAL FILM OR PATCH
The present invention provides a pharmaceutical composition for delivering palonosetron through the buccal mucosa or sublingual mucosa. The pharmaceutical...
2017/0367968 Topical Formulations Containing Palm Pollen
Compositions are provided that include date palm pollen or an extract thereof. The compositions may be formulated for topical use in methods of treatment or...
2017/0367967 ALKALIZING DELIVERY SYSTEM FOR PROMOTING AN OPTIMAL ORAL SALIVARY pH
An alkalizing delivery system for promoting healthier saliva is provided. The alkalizing delivery system may take many portable forms that include a saliva...
2017/0367966 DISPERSION OF POLYMER PARTICLES IN A NON-AQUEOUS MEDIUM AND COSMETIC USE THEREOF
The invention relates to a dispersion of polymer particles stabilized with a stabilizer in a nonaqueous medium containing at least one hydrocarbon-based oil,...
2017/0367965 USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN...
The present invention relates to the cosmetic use as a skin refreshing agent of the combination of at least one associative nonionic polyether polyurethane and...
2017/0367964 POLYLACTIC ACID-CONTAINING AQUEOUS DISPERSION
Provided is a polylactic-acid-containing aqueous dispersion capable of forming a transparent film at room temperature. A polylactic-acid-containing aqueous...
2017/0367963 AMPHIPHILIC SUSPENSION AND STABILITY AGENT FOR ANTIDANDRUFF HAIR CARE COMPOSITIONS
A hair care composition comprising: i) at least one crosslinked nonionic amphiphilic suspending polymer; ii) at least one anionic surfactant; iii) at least one...
2017/0367962 HAIR COMPOSITION
A rinse off hair treatment composition comprising; a. a pressure sensitive adhesive emulsion comprising one or more pressure sensitive polymer, wherein the...
2017/0367961 COSMETIC EMULSIONS
Cosmetic emulsions are disclosed that can remain stable even with relatively high salt based cosmetic astringent content. In one aspect, an emulsion can...
2017/0367960 WATER-BASED COSMETIC
A water-based cosmetic including: agar having a weight average molecular weight of 10,000 to 60,000 (component (A)); xanthan gum (component (B)); and a...
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