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Patent # Description
2018/0016609 A Process for the Preparation of Nucleic Acid by Means of 3'-O-Azidomethyl Nucleotide Triphosphate
The invention relates to a method of nucleic acid synthesis comprising the use of 3'-O-azidomethyl blocked nucleotide triphosphates which comprises the step of...
2018/0016608 A STRAIN FOR PRODUCTION OF GLUCOSAMINE BY MICROBIAL FERMENTATION, AND ITS METHODS
This Invention relates to, for production of N-acetyl-D-glucosamine and D-glucosamine by microbial fermentation: A nongenetic recombinant strain, preserved in...
2018/0016607 CONTROLLING THE PRETREATMENT OF A SOFTWOOD STARTING MATERIAL
The present invention relates to a method for pretreating a softwood starting material comprising the following steps: a) pretreating the softwood starting...
2018/0016606 Methods of Degrading or Hydrolyzing a Polysaccharide
The invention provides a method of degrading or hydrolyzing a polysaccharide, preferably cellulose or chitin, comprising contacting said polysaccharide with...
2018/0016605 BIOMASS OF THE MICROALGAE SCHIZOCHYTRIUM MANGROVEI AND METHOD FOR PREPARING SAME
The invention concerns a strain of Shizochytrium mangrovei filed on 22 Nov. 2012 with the CNCM as number 1-4702 having the ability to produce a high quantity...
2018/0016604 PROCESS FOR PRODUCING ITACONIC ACID UNDER ANAEROBIC CONDITIONS
The present invention relates to a method for the production of itaconic acid, which method comprises fermenting a recombinant cell capable of producing...
2018/0016603 PRODUCTION OF ARABITOL
A method for producing arabitol may include providing a fermentation culture having a microorganism and a carbon source; allowing the microorganism to ferment...
2018/0016602 SYSTEM AND PROCESS FOR ADDING PRE-FERMENTATION SEPARATED NON-FERMENTABLES TO A POST-FERMENTATION STREAM
A system and process is disclosed for adding pre-fermentation separated non-fermentables, e.g., fiber, germ/oil, and/or protein, to a post-fermentation stream...
2018/0016601 Methods for Modulating Genome Editing
Provided herein are methods and kits for modulating genome editing of target DNA. The invention includes using small molecules that enhance or repress...
2018/0016600 RETROVIRAL TRANSDUCTION USING POLOXAMERS
The present invention relates to a method for transducing a target cell, the method comprising the step of contacting a target cell with a retroviral vector...
2018/0016599 Recombinant Cytomegalovirus Vectors As Vaccines For Tuberculosis
The present disclosure provides cytomegalovirus vectors encoding fusion proteins comprising Mycobacterium tuberculosis (Mtb) antigens, nucleic acid molecules...
2018/0016598 Simian Adenoviruses SAdV-43, -45, -46, -47, -48, -49, and -50, and Uses Thereof
A recombinant vector comprises simian adenovirus 43, 45, 46, 47, 48, 49 or 50 sequences and a heterologous gene under the control of regulatory sequences. A...
2018/0016597 Method for Producing Polyploidized Megakaryocyte and Platelets
An object of the present invention is to provide a method of promoting polyploidization of megakaryocytes and thereby producing highly polyploidized...
2018/0016596 NUCLEIC ACID CONSTRUCTS, PLANTS COMPRISING SAME AND USES THEREOF IN ENHANCING PLANT PEST RESISTANCE AND...
Nucleic acid constructs encoding Geraniol Synthase (GS), Geraniol Reductase (GR), Geraniol Dehydrogenase (GD), and/or Citral Reductase (CR) and plants...
2018/0016595 TOBACCO MOSAIC VIRUS RESISTANT N'AU GENE AND CLONING METHODS AND APPLICATIONS THEREOF
The invention relates to the isolation and the cloning and breeding application of a tobacco mosaic virus (TMV) resistant N'au gene. The invention discloses...
2018/0016594 A GENE CAPABLE OF ENHANCING SALICYLIC ACID-INDUCED CELL DEATH IN A PLANT CELL AND CONTRIBUTING TO RESISTANCE TO...
The Applicant has identified a novel DON-responsive orphan gene (ENST1--SEQ ID NO: 1), and its promoter, which features DON-responsive elements, which can be...
2018/0016593 HERBICIDE-RESISTANT SUNFLOWER PLANTS, POLYNUCLEOTIDES ENCODING HERBICIDE-RESISTANT ACETOHYDROXYACID SYNTHASE...
Herbicide-resistant sunflower plants, isolated polynucleotides that encode herbicide-resistant and wild-type acetohydroxyacid synthase large subunit 1 (AHASL1)...
2018/0016592 Modulating Laccase Enzyme to Regulate Cell Wall Biosynthesis and Recalcitrance in Plants
This disclosure provides genetically modified plants having desirable levels of sugar release and syringyl/guaiacyl (S/G) ratio; methods of genetically...
2018/0016591 ELITE EVENT CANOLA NS-B50027-4
The present embodiments relate to elite event NS-B50027-4, seeds and oils obtained from NS-B50027-4, progeny derived from NS-B50027-4, the genetic and...
2018/0016590 INBRED TRANSGENIC CANOLA LINE NS-B50027-4 AND SEEDS THEREOF
The present embodiments relate to inbred transgenic canola line NS-B50027-4; seeds and oils obtained from NS-B50027-4; and progeny derived from NS-B50027-4. In...
2018/0016589 METHOD FOR CONDUCTING SITE-SPECIFIC MODIFICATION ON ENTIRE PLANT VIA GENE TRANSIENT EXPRESSION
The present invention discloses a method for site-directed modification of whole plant through gene transient expression. The method as provided for conducting...
2018/0016588 YEAST CELLS EXPRESSING AMYLOID BETA AND USES THEREFOR
Disclosed are yeast cells expressing a polypeptide comprising a signal sequence and a human amyloid beta protein. Also disclosed are methods of screening yeast...
2018/0016587 METHOD TO IMPROVE LACTOCOCCUS PRESERVATION
Lactococcus lactis strains with improved preservation characteristics, and improved acid and bile salt tolerance are disclosed. More specifically, a L. lactis...
2018/0016586 L-ARABINOSE ASSIMILATION PATHWAY AND USES THEREOF
The present invention relates to a new L-arabinose assimilation pathway and uses thereof. In particular, the present invention relates to polypeptides...
2018/0016585 METHOD FOR IMPROVING HETEROLOGOUS SYNTHESIS OF ESCHERICHIA COLI INTO POLYKETIDES AND USE OF SAME
The present invention relates to a method for improving the heterologous synthesis of a polyketide by E. coli and use thereof. The yield of the polyketide...
2018/0016584 METHODS AND COMPOSITIONS FOR UNSILENCING IMPRINTED GENES
The present invention provides methods and compositions for inducing expression of Ube3a in a cell by contacting the cell with a topoisomerase inhibitor....
2018/0016583 COMPOSITIONS AND METHODS FOR SILENCING HEPATITIS B VIRUS GENE EXPRESSION
The present invention provides compositions comprising therapeutic nucleic acids such as siRNA that target Hepatitis B virus (HBV) gene expression, lipid...
2018/0016582 DNA APTAMER BINDING TO NON-SMALL CELL LUNG CANCER CELLS (H1975)
The objective of the present invention is to provide a novel DNA aptamer useful for the diagnosis, treatment, and prevention of metastasis, and the like, of...
2018/0016581 NUCLEIC ACID COMPOUNDS FOR BINDING GROWTH DIFFERENTIATION FACTOR 8
Described herein are aptamers capable of binding to growth differentiation factor 8 (GDF8) protein; compositions comprising a GDF8 binding aptamer; and methods...
2018/0016580 MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD
Using a morpholino nucleotide wherein 5'-hydroxy group or a hydroxy group present on the substituent of the 5'-hydroxy group is protected by a protecting group...
2018/0016579 METHODS FOR THE TREATMENT OF LEBER CONGENITAL AMAUROSIS
The present invention relates to a method for treating a Leber congenital amaurosis in a patient harbouring the mutation c.2991+1655 A>G in the CEP290 gene,...
2018/0016578 METHODS AND AGENTS TO INCREASE THERAPEUTIC DYSTROPHIN EXPRESSION IN MUSCLE
Agents and methods for increasing dystrophin protein expression in muscle through blocking of specific microRNAs and microRNA binding sites on the dystrophin...
2018/0016577 TREATMENT OF FACIOSCAPULOHUMERAL DYSTROPHY
The present invention relates to nucleic acids, compositions and methods for the treatment of facioscapulohumeral dystrophy.
2018/0016576 Novel Therapeutic Agent for Septicemia, and a Method for Screening for Same
The present invention provides a therapeutic agent for sepsis and/or septic shock and a method for screening for the therapeutic agent. The present invention...
2018/0016575 LNA Gapmer Oligonucleotides Comprising Chiral Phosphorothioate Linkages
The present relates to LNA gapmer antisense oligonucleotides which comprise stereodefined phosphoramidite linkages. The use of stereodefined phosphoramidite...
2018/0016574 EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY
Antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon 44 skipping are described.
2018/0016573 BIOMOLECULE ISOLATION
Methods, devices and systems for handling sample liquids, encapsulating liquids and magnetic particles are disclosed.
2018/0016572 COMPOSITIONS AND METHODS FOR DETECTING NUCLEIC ACID REGIONS
Provided are methods, compositions, reagents, kits that are useful for detecting a specific nucleic acid region in genome with high efficiency and high...
2018/0016571 TRANSPOSASE COMPOSITIONS FOR REDUCTION OF INSERTION BIAS
Presented herein are methods and compositions for tagmentation of nucleic acids. The methods are useful for generating tagged DNA fragments that are...
2018/0016570 SYSTEM FOR GENERATING HIGH CONCENTRATION FACTORS FOR LOW CELL DENSITY SUSPENSIONS
Acoustophoretic devices and methods for concentrating targeted biological cells in a reduced volume using multi-dimensional acoustic standing waves are...
2018/0016569 Nanocaged Enzymes with Enhanced Catalytic Activity and Increased Stability
The present disclosure describes a nanoparticle comprising a three dimensional DNA nanocage and a payload biological macromolecule, and methods of assembly...
2018/0016568 ENGINEERED PHENYLALANINE AMMONIA LYASE POLYPEPTIDES
The present invention provides engineered phenylalanine ammonia-lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the...
2018/0016567 METHOD FOR PREPARATION OF THROMBIN
The present invention is directed to methods for the production of thrombin from a source of prothrombin using a given BaSO.sub.4 reagent as an adsorbent of...
2018/0016566 DETERGENT COMPOSITION COMPRISING PROTEASE AND AMYLASE VARIANTS
The present invention relates to detergent compositions comprising protease variants and alpha-amylases or variants thereof. Furthermore, the present invention...
2018/0016565 MANNANASE AND USE THEREOF
A novel mannanase. A polypeptide having a specific amino acid sequence such as the amino acid represented by SEQ ID NO:2 exhibits a mannanase activity....
2018/0016564 ALPHA-GALACTOSIDASE A FROM MATERIAL CONTAINING CONTAMINANT HOST CELL PROTEINS
Disclosed is a method for production of recombinant human alpha-galactosidase A (rh alpha-Gal A) in a large scale, with a high purity. The method comprises the...
2018/0016563 ALPHA-GLUCOSIDASE, COMPOSITIONS & METHODS
The present disclosure relates to polypeptides having alpha-glucosidase activity isolated, derived or derivable from Rasamsonia or engineered polypeptides...
2018/0016562 ANCESTRAL PROTEINS
The invention provides a method tar increasing the stability and/or activity of a polypeptide at low pH and/or elevated temperatures The invention farther...
2018/0016561 ROTAVIRUS-LIKE PARTICLE PRODUCTION IN PLANTS
A method of producing a rotavirus-like particle (RLP) in a plant is provided. The method comprises expressing within a host or host cell for example a plant,...
2018/0016560 NOVEL INFLUENZA VIRUS
The present invention provides a novel influenza virus wherein both the NS and the PB1 gene segments are modified and wherein the PB1-F2 open reading frame is...
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