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Patent # Description
2018/0016255 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing...
A medicament or pharmaceutical composition for the treatment of exacerbations of asthma and chronic obstructive pulmonary disease, which is a compound having...
2018/0016254 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing...
A medicament or pharmaceutical composition for the treatment of a respiratory tract disease, which is a compound having the following formula: ##STR00001## ...
2018/0016253 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing...
Biologically active glutarimide derivatives of the following formula: ##STR00001## or a pharmaceutically acceptable salt thereof.
2018/0016252 SOMATOSTATIN MODULATORS AND USES THEREOF
Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such...
2018/0016251 NEW BENZIMIDAZOLE DERIVATIVES AS ANTIHISTAMINE AGENTS
The invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, a method of synthesis of said compounds,...
2018/0016250 DIFUNCTIONAL MONOMER COMPOUNDS CONTAINING CLICKABLE PENDANT FURYL GROUP AND POLYMERS THEREFROM
The present invention discloses novel difunctional monomers compound containing pendant clickable furyl group of formula (I), process for the preparation and...
2018/0016249 Methods of Treating an Overweight or Obese Subject
The disclosure herein generally relates to methods of treating an overweight or obese condition, and overweight- or obesity-related conditions. In one...
2018/0016248 EPOXIDATION PROCESS
A method for producing ethylene oxide comprising: a) providing one or more feed components, wherein the one or more feed components contains at least ethylene...
2018/0016247 CYCLIC PROTEIN TYROSINE KINASE INHIBITORS
Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of...
2018/0016246 PROCESS FOR PREPARATION OF POLYMORPHIC FORM OF MIRABEGRON
The present invention is directed to process for preparation of .alpha.-form crystal of Mirabegron, ...
2018/0016245 METHODS FOR TREATING VASCULAR LEAK SYNDROME
Disclosed are methods for treating Vascular Leak Syndrome. Further disclosed are methods for treating vascular leakage due to inflammatory diseases, inter...
2018/0016244 DEUTERIUM-SUBSTITUTED OXADIAZOLES
Described are deuterated modulators of S1P1 receptors, pharmaceutical compositions thereof, and methods of use thereof. ##STR00001##
2018/0016243 HUMAN HELICASE DDX3 INHIBITORS AS THERAPEUTIC AGENTS
The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for...
2018/0016242 2,4-DIOXO-QUINAZOLINE-6-SULFONAMIDE DERIVATIVES AS INHIBITORS OF PARG
The present invention relates to compounds of formula I that function as inhibitors of PARG (Poly ADP-ribose glycohydrolase) enzyme activity wherein R.sub.1a,...
2018/0016241 IMPROVED PROCESS FOR PREPARING STATIN PRECURSOR
The present invention relates to a process for preparing a statin precursor, which process comprises a first reaction step, wherein a ...
2018/0016240 SUBSTITUTED PYRIDAZINE CARBOXAMIDE COMPOUNDS
The new pyridazine derivatives have unexpected drug properties as inhibitors of protein kinases especially against ALK and are useful in treating disorders...
2018/0016239 SUBSTITUTED PYRAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
The present invention relates to compounds according to Formula (I-1) and pharmaceutically acceptable salts thereof. Such compounds can be used in the...
2018/0016238 PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS
The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.
2018/0016237 Morphan And Morphinan Analogues, And Methods Of Use
The present application relates to analogues of morphan and morphinan, compositions thereof, and methods for treating a disease or condition comprising...
2018/0016236 PYRIDIC KETONE DERIVATIVES, METHOD OF PREPARING SAME, AND PHARMACEUTICAL APPLICATION THEREOF
Compounds for the preparation of pyridone derivatives are provided. In particular, compounds of formula (IA) are provided, wherein the variable groups are as...
2018/0016235 PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS
The invention relates to pyridone amide compounds of formula I and I' or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: ...
2018/0016234 HERBICIDAL PHENYLPYRIDINES
The present invention relates to phenylpyridines of formula (I) ##STR00001## wherein the variables are defined according to the description, processes and...
2018/0016233 PHOTOSTABLE COMPOUNDS, ABSORBING COMPOUNDS AND USES THEREOF
The present invention describes compounds and uses thereof in applications relating to absorption of electromagnetic energy. Preferred compounds are double...
2018/0016232 SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES
Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic...
2018/0016231 METHOD FOR PREPARING STRUCTURED DIRECTING AGENT
Provided is a method for preparing a structure directing agent (SDA) for crystalline molecular sieve synthesis comprising the steps of (a) hydrolyzing analkyl...
2018/0016230 Salts of Prostaglandin Analog Intermediates
The present invention relates to crystalline 1-adamantanamine salts, and polymorphic forms thereof, of prostaglandin analog intermediates of formula 3a, 4a and...
2018/0016229 USE OF ISOTHIOCYANATE FUNCTIONAL SURFACTANTS AS NRF2 INDUCERS TO TREAT EPIDERMOLYSIS BULLOSA SIMPLEX AND...
The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application...
2018/0016228 PROCESSES FOR THE CONVERGENT SYNTHESIS OF CALICHEAMICIN DERIVATIVES
This invention describes processes for the convergent synthesis of calicheamicin derivatives, and similar analogs using bifunctional and trifunctional linker...
2018/0016227 PROCESS FOR THE SYNTHESIS OF DIFLUOROMETHYL ETHER-BASED COMPOUNDS
The present application relates to a novel process for the preparation of difluoromethyl ether-based derivatives from, for example, aliphatic and aromatic...
2018/0016226 4-AZIDOBUTYLAMINES AND PROCESSES FOR PREPARING
Neat 4-azidobutylamine and sails of 4-azidobutylamine and processes for producing the same are described herein. Amines represent a large class of organic...
2018/0016225 TETRACYCLINE COMPOUNDS HAVING TARGET THERAPEUTIC ACTIVITIES
Methods and compounds for treating diseases with tetracycline compounds having a target therapeutic activity are described.
2018/0016224 PREPARATION OF CHIRAL AMIDES AND AMINES
This invention provides a convenient method for converting oximes into enamides. The process does not require the use of metallic reagents. Accordingly, it...
2018/0016223 FLUORINE-CONTAINING ETHER MONOCARBOXYLIC ACID AMINOALKYL ESTER AND A METHOD FOR PRODUCING THE SAME
A fluorine-containing ether monocarboxylic acid aminoalkyl ester represented by the general formula: ...
2018/0016222 TREPROSTINIL DERIVATIVES AND COMPOSITIONS AND USES THEREOF
The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any...
2018/0016221 SPIROFURANONE COMPOUNDS, DERIVATIVES THEREOF AND PROCESSES FOR THEIR PREPARATION
The present invention provides compounds comprising fused tricyclic backbone structure and processes for their preparation. The invention further provides...
2018/0016220 IRON (III) CITRATE, SUBSTANTIALLY FREE OF BETA-IRON HYDROXIDE OXIDE
This invention provides a method for producing high-purity iron(III) citrate substantially free of beta-iron hydroxide oxide, high-purity iron(III) citrate...
2018/0016219 PROCESS FOR PRODUCTION OF ACRYLIC ACID
Provided are integrated processes for the conversion of beta propiolactone to acrylic acid. Systems for the production of acrylic acid are also provided.
2018/0016218 CATALYTIC MEMBRANE REACTOR FOR DIMETHYL ETHER SYNTHESIS FROM CARBON DIOXIDE AND HYDROGEN
Methods and systems or devices for synthesis of dimethyl ether (DME) from carbon dioxide and hydrogen are provided. A high surface area hollow fiber catalytic...
2018/0016217 METHODS FOR PREPARING GLYCEROL TERT-BUTYL ETHERS
Methods for generating glycerol tert-butyl ethers include reacting isobutylene and glycerol in the presence of a catalyst and a co-solvent cum co-reactant to...
2018/0016216 DECARBOXYLATION OF CANNABIDIOLIC ACID IN HEMP BIOMASS & HEMP EXTRACT
Provided is a decarboxylating carboxylic acids of cannabinoids in hemp extract or hemp biomass in which the hemp extract or hemp biomass is heated to a...
2018/0016215 Butanol Purification
Provided are methods for removing one or more components from a butanol based composition. The methods comprise providing a butanol based composition...
2018/0016214 ONE VESSEL PROCESS FOR MAKING 1,2-PROPANEDIOL FROM A HIGH FRUCTOSE FEEDSTOCK
A process is described for directly converting a high fructose feedstock to a product mixture including one or more lower polyols in which 1,2-propanediol is...
2018/0016213 METHOD FOR STORING TETRAFLUOROPROPENE AND CONTAINER FOR STORING TETRAFLUOROPROPENE
To provide a method for stably storing tetrafluoropropene filled in a container for e.g. storage or transportation, without occurrence of reaction such as...
2018/0016212 AEROSOL COMPOSITIONS CONTAINING FLUORINE SUBSTITUTED OLEFINS AND METHODS AND SYSTEMS USING SAME
Various compositions, including particularly aerosol compositions, containing fluorinated olefins, including particularly tetra- and penta-fluoropropenes, in a...
2018/0016211 PROCESS FOR THE PREPARATION OF BENZONORBORNENES
The present invention relates to a novel a process for the preparation of 9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-ylamine which process...
2018/0016210 COMPOUND BED DESIGN WITH ADDITIONAL REGENERATION STEPS FOR REMOVAL OF VARIOUS SULFUR SPECIES FROM LIGHTER...
A process is provided to remove impurities including water, mercaptans, carbonyl sulfide and hydrogen sulfide from hydrocarbon streams containing from 100 to...
2018/0016209 METHOD AND APPARATUS FOR SEPARATING ALKYL AROMATIC HYDROCARBON
A method for separating an alkyl aromatic hydrocarbon, the method having a step of adding a first diluent and an extractant having a superacid to a mixture...
2018/0016208 METHOD FOR PRODUCING CONJUGATED DIOLEFIN
A method for producing a conjugated diolefin is configured as follows. A monoolefin having four or more carbon atoms is fed from a monoolefin feed nozzle(s)...
2018/0016207 Treatment of Aromatic Alkylation Feedstock
In a process and system for treatment of feed stocks comprising alkylating agent and metal salts, the metal salts are removed from the feedstock by an...
2018/0016206 ETHYLENE TETRAMERIZATION CATALYST SYSTEM AND METHOD FOR PREPARING 1-OCTENE USING THE SAME
Disclosed herein is a method of preparing 1-octene at high activity and high selectivity while stably maintaining reaction activity by tetramerizing ethylene...
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