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Patent # Description
2018/0022713 HETEROARYL COMPOUNDS AND USES THEREOF
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
2018/0022712 NEGATIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 3
Described are negative allosteric modulators of metabotropic glutamate receptor 3 (mGlu3), pharmaceutical compositions including the compounds, and methods of...
2018/0022711 NOVEL CRYSTAL FORMS OF THE MONOSODIUM SALT OF FORAMSULFURON
The present invention relates to a novel crystal form of the monosodium salt of foramsulfuron, a method for preparing this crystal form, use thereof in...
2018/0022710 ISOTOPOLOGUES OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRI- ...
Provided herein are isotopologues of Compound A, which are enriched with isotopes such as, for example, deuterium. Pharmaceutical compositions comprising the...
2018/0022709 Compositions and Methods for Treating Toxoplasmosis, Cryptosporidiosis, and Other Apicomplexan Protozoan...
Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment...
2018/0022708 PROCESSES FOR PREPARING ASK1 INHIBITORS
The present disclosure provides processes for the preparation of a compound of formula: ##STR00001## which exhibits apoptosis signal-regulating kinase ("ASK1")...
2018/0022707 THERAPEUTIC COMPOUNDS AND USES THEREOF
The present invention relates to compounds useful as inhibitors of one or more histone demethylses, such as KDM2b. The invention also provides pharmaceutically...
2018/0022706 CANNABINOID RECEPTOR MEDIATING COMPOUNDS
A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a CB.sub.1 receptor mediating scaffold conjugated to (ii) a second...
2018/0022705 CANNABINOID RECEPTOR MEDIATING COMPOUNDS
A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a CB.sub.1 receptor mediating scaffold conjugated to (ii) a second...
2018/0022704 PROCESS FOR THE PREPARATION OF HISTAMINE H3 RECEPTOR MODULATORS
The present invention is directed to novel processes for the preparation of histamine H3 receptor modulators, in the treatment of for example, cognitive...
2018/0022703 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN...
An herbicidal composition containing (a) a pyridine or pyrimidine carboxylic acid component and (b) a second cereal or rice herbicide component provides...
2018/0022702 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS
Provided herein are compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat diseases or disorders...
2018/0022701 4-HETEROARYL SUBSTITUTED BENZOIC ACID COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
The present invention relates to compounds according to Formula I (Formula I), and pharmaceutically acceptable salts or solvates thereof. Such compounds can be...
2018/0022700 COMPOUND CONTAINING INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF
Disclosed are a compound as shown by the following formula 1, and a pharmaceutically acceptable salt, an ester, a hydrate and an organic solvate thereof. In...
2018/0022699 ARYL SUBSTITUTED INDOLES AND THE USE THEREOF
The invention relates to aryl and heteroaryl substituted compounds of Formula (I), and pharmaceutically acceptable salts, prodrugs, or solvates thereof,...
2018/0022698 NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA
Methods of treatment useful in the inducement or maintenance of anesthesia in a subject are provided. The methods comprise administering to a subject in need...
2018/0022697 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME
Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the...
2018/0022696 NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS
The present invention relates to novel N-acyl-diarysulfonamides acting as inhibitors of bacterial aminoacyl-tRNA synthetase. These can be used as medicines or...
2018/0022695 GLUCAGON ANTAGONISTS
Provided herein are compounds, including enantiomerically pure forms thereof, and pharmaceutically acceptable salts or co-crystals and prodrugs thereof which...
2018/0022694 PROCESS FOR FLUORINATION OF SULPHONYL HALIDE COMPOUNDS
The present disclosure relates to the preparation of a compound of formula (I) comprising an --SO.sub.2F function, R--SO.sub.2F, by reacting a compound of...
2018/0022693 COMPOUNDS
The present invention describes compounds and uses thereof in applications relating to absorption of electromagnetic energy. Preferred compounds are double...
2018/0022692 METHOD FOR PRODUCING 2-AMINOETHYLMETHACRYLATE HYDROCHLORIDE
Provided is a method for producing 2-aminoethyl methacrylate hydrochloride that, according to one embodiment, includes a step (A) for reacting a ketimine...
2018/0022691 High Purity Ethylenediamine for Semiconductor Applications
Ethylenediamine (EDA) compositions and methods for making the EDA that is suitable for use in thin-film semiconductor processing applications, are disclosed....
2018/0022690 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF NEP INHIBITORS
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril....
2018/0022689 Alkyl Aromatic Hydroalkylation For The Production of Plasticizers
Provided are compounds of the following: ##STR00001## wherein R.sub.1 is a saturated or unsaturated cyclic hydrocarbon optionally substituted with an alkyl...
2018/0022688 COMPOUND, AND SEPARATION METHOD, SYNTHESIS METHOD AND USE THEREOF
The invention relates to new compounds as well as a separation method, a synthetic method and use thereof. It is demonstrated by an assay on activity that the...
2018/0022687 METHOD FOR PREPARING DI- OR TRICARBOXYLIC ESTERS BY ALKOXYCARBONYLATION OF DIENES HAVING CONJUGATED DOUBLE BONDS
The invention relates to a method comprising the method steps of: a) initially charging a diene having two conjugated double bonds; b) adding a phosphine...
2018/0022686 PROCESS FOR THE ALKOXYCARBONYLATION OF OLEFINS IN A MEDIUM HAVING A LOW BRONSTED ACID CONCENTRATION
Process comprising the following process steps: a) introducing an ethylenically unsaturated compound; b) adding a ligand-metal complex comprising Pd and a...
2018/0022685 PROCESS FOR THE ALKOXYCARBONYLATION OF ETHERS
The invention relates to a process comprising the following process steps: a) introducing an ether having 3 to 30 carbon atoms; b) adding a phosphine ligand...
2018/0022684 PROCESS FOR THE PREPARATION OF ESTERS BY MEANS OF CARBONYLATION OF ETHERS
The invention relates to a process comprising the process steps of: a) initially charging an ether having from 3 to 30 carbon atoms; b) adding a phosphine...
2018/0022683 METHOD FOR PREPARING SUBSTITUTED ALKYL CYCLOALKANONES
The present invention relates to a method for producing a substituted alkyl cycloalkanone of formula (I), having the alkylation of a cycloalkanone of formula...
2018/0022682 METHOD FOR ESTERIFICATION OF A DIOL USING A REACTIVE DISTILLATION
The invention relates to a conversion method that is fed with a diol feedstock that comprises at least 90% by weight of diol and a carboxylic acid feedstock...
2018/0022681 A NOVEL PROCESS FOR THE PREPARATION OF HYDROXYL FUNCTIONAL ESTERS AND POLYESTERS THEREFROM
The present invention relates to a novel process for the preparation of a linear monomer alkyl lactyl lactate by a simple esterification reaction of acid with...
2018/0022680 METHOD FOR PRODUCING ACRYLIC ACID
The objective of the present invention is to provide a method for efficiently producing acrylic acid while troubles not only in a waste oil handling after...
2018/0022679 HETEROGENEOUS METAL-FREE CATALYST
The inventive concepts disclosed and/or claimed herein relate generally to catalysts and, more particularly, but not by way of limitation, to a heterogeneous,...
2018/0022678 METHOD FOR CATALYTIC GENERATION OF FORMIC ACID AT AN OXYGEN PARTIAL PRESSURE BELOW 1 BAR AND REGENERATION OF...
The invention relates to a method for the catalytic generation of formic acid at an oxygen partial pressure below 1 bar and regeneration of the catalyst used...
2018/0022677 DISTILLATION PROCESS FOR PRODUCTION OF ACRYLIC ACID
Provided are integrated processes for the conversion of beta propiolactone to acrylic acid. Systems for the production of acrylic acid are also provided.
2018/0022676 SINGLE-STEP CONVERSION OF N-BUTYRALDEHYDE TO 2-ETHYLHEXANAL
Disclosed is a method of making and using a titania supported palladium catalyst for the single step synthesis of 2-ethylhexanal from a feed of ...
2018/0022675 PRODUCTION METHOD FOR INCLUSION COMPOUND
A method for producing a thermodynamically more stable clathrate compound including at least one compound selected from the group consisting of ...
2018/0022673 PROCESS FOR CONVERTING METHANOL TO HYDROCARBONS SUITABLE FOR USE AS GASOLINE OR BLENDSTOCK
The present application relates to a process for production of hydrocarbons comprising the steps of converting a feed stream comprising alcohols, ethers or...
2018/0022672 HEAT TRANSFER COMPOSITIONS, METHODS AND SYSTEMS
Various compositons, including particularly aerosol compositions, containing fluorinated olefins, including particularly tetra- and penta-fluorpropenes, in a...
2018/0022671 CHROMIA BASED FLUORINATION CATALYST
A chromia-based fluorination catalyst comprising at least one additional metal selected from zinc, nickel, aluminium and magnesium in which from 0.1 to 8.0% by...
2018/0022670 METHOD FOR EMULSION REMOVAL IN AMINE REMOVAL UNIT
A method for removal of an organic amine from a hydrocarbon stream includes mixing the hydrocarbon stream including the amine with an aqueous inorganic acid in...
2018/0022669 Process for Xylenes Isomerization
A process for the isomerization of a para-xylene depleted, meta-xylene rich stream under at least partially liquid phase conditions using ZSM-23 with an...
2018/0022668 HYDROGENATION METHOD
The present subject matter relates generally to methods for treating an organic feed. More specifically, the present subject matter relates to methods for...
2018/0022667 Hydrocarbon Dehydrocyclization in the Presence of Carbon Dioxide
The invention relates to converting non-aromatic hydrocarbon in the presence of CO.sub.2 to produce aromatic hydrocarbon. CO.sub.2 methanation using molecular...
2018/0022666 OLIGOMERIZATION OF ETHYLENE TO LIQUID TRANSPORTATION FUELS WITH POST SYNTHESIS TREATED ZSM-5 CATALYST
A process for post synthesis treatment of ZSM-5 catalyst for converting ethylene to liquid fuel products providing substantially improved catalyst life. The...
2018/0022665 OLIGOMERIZATION OF ETHYLENE TO LIQUID TRANSPORTATION FUELS WITH POST SYNTHESIS TREATED ZSM-5 CATALYST
A process for post synthesis treatment of ZSM-5 catalyst for converting ethylene to liquid fuel products providing substantially improved catalyst life. The...
2018/0022664 OLIGOMERIZATION OF ETHYLENE TO LIQUID TRANSPORTATION FUELS WITH POST SYNTHESIS TREATED ZSM-5 CATALYST
A process for post synthesis treatment of ZSM-5 catalyst for converting ethylene to liquid fuel products providing substantially improved catalyst life. The...
2018/0022663 REACTIVE BURNING RATE ACCELERATORS, SOLID ENERGETIC MATERIALS COMPRISING THE SAME, AND METHODS OF USING THE SAME
A reactive burning rate accelerator is provided that is configured to be at least partially embedded in a solid energetic material and comprises at least one...
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