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Patent # Description
2018/0023117 METHOD FOR LYOPHILIZATION OF COMPOSITION FOR MULTIPLE TARGET NUCLEIC ACID SEQUENCE AMPLIFICATION REACTION
The present invention relates to a method for lyophilizing a composition for multiple target nucleic acid sequence amplification reaction and a lyophilizate...
2018/0023116 METHOD FOR PREPARING SINGLE-STRANDED DNA PRODUCT
The purpose of the present invention is to provide the technique of a method for preparing a highly precise single-stranded DNA that makes it possible to...
2018/0023115 Nanopore Detection of Target Polynucleotides From Sample Background
Disclosed herein are methods and compositions for detection of target polynucleotides in a mixed sample by amplification of the target polynucleotide and...
2018/0023114 Labile Linkers for Biomarker Detection
Disclosed herein are methods and compositions for electronic detection and/or quantification of enzymes or enzymatic activity in a sample using a pore system.
2018/0023113 Acyl-CoA Dehydrogenases Micro/Nano Enzyme Assay
Provided herein are methods of measuring acyl-CoA dehydrogenase activity in a biological sample in a multiwell microplate setting.
2018/0023112 HIGH RESOLUTION SYSTEMS, KITS, APPARATUS, AND METHODS USING MAGNETIC BEADS FOR HIGH THROUGHPUT MICROBIOLOGY...
A method of transferring material from a first microfabricated device to a second microfabricated device. At least one magnetic bead is loaded into at least...
2018/0023111 APPARATUS FOR CHARACTERIZING BIOLOGICAL OBJECTS
In order to quantitatively characterize biological objects, for example individual cells, a stimulus is applied to a biological object (8) in a contactless...
2018/0023110 METHOD FOR PREPARING FUNCTIONAL POLYPEPTIDE THROUGH MULTIMODE ULTRASONIC ENHANCING ENZYMOLYSIS
The invention is about methods for preparing functional polypeptide by multi-mode ultrasound enhancement on enzymolysis, and it relates to the field of...
2018/0023109 ASSAY AND OTHER REACTIONS INVOLVING DROPLETS
The present invention generally relates to droplets and/or emulsions, such as multiple emulsions. In some cases, the droplets and/or emulsions may be used in...
2018/0023108 NOVEL USE
The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of...
2018/0023107 METHODS FOR MITIGATING THE INHIBITORY EFFECTS OF LIGNIN AND SOLUBLE PHENOLICS FOR ENZYMATIC CONVERSION OF CELLULOSE
Disclosed herein are methods for improving ethanol production from biomass sources by blocking cellulose from binding to lignin.
2018/0023106 IN-SITU BIOSTIMULATION OF THE HYDROLYSIS OF ORGANIC MATTER FOR OPTIMIZING THE ENERGY RECOVERY THEREFROM
Some embodiments are directed to a process for the treatment of organic waste which couples in situ biostimulation to produce hydrolytic enzymes and hydrolysis...
2018/0023105 Genetically Modified Cell and Process for Use of Said Cell
The present invention relates to the field of biotransformation of furanic compounds. More particular the present invention relates to novel genetically...
2018/0023104 MATERIALS AND METHODS FOR DIRECTING CARBON FLUX AND INCREASED PRODUCTION OF CARBON BASED CHEMICALS
This disclosure relates to genome-scale attenuation or knockout strategies for directing carbon flux to certain carbon based building blocks within the...
2018/0023103 METHODS AND MATERIALS FOR BIOSYNTHESIZING MULTIFUNCTIONAL, MULTIVARIATE MOLECULES VIA CARBON CHAIN MODIFICATION
This document describes biochemical pathways for producing a difunctional product having an odd number of carbon atoms in vitro or in a recombinant host, or...
2018/0023102 MATERIALS AND METHODS UTILIZING BIOTIN PRODUCING MUTANT HOSTS FOR THE PRODUCTION OF 7-CARBON CHEMICALS
Disclosed are methods for regulating biosynthesis of at least one of pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine,...
2018/0023101 MICROORGANISMS AND METHODS FOR THE CO-PRODUCTION OF ETHYLENE GLYCOL AND THREE CARBON COMPOUNDS
The present application relates to recombinant microorganisms useful in the biosynthesis of monoethylene glycol (MEG) and one or more three-carbon compounds...
2018/0023100 INCREASED ETHANOL PRODUCTION BY THERMOPHILIC MICROORGANISMS WITH DELETION OF INDIVIDUAL HFS HYDROGENASE SUBUNITS
Disclosed are methods for engineering bacteria, for example, Thermoanaerobacterium saccharolyticum, that convert biomass to ethanol at high yield by deleting a...
2018/0023099 PROCESSES FOR PRODUCING FERMENTATION PRODUCTS
The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and...
2018/0023098 NUCLEIC ACID, FUSION PROTEIN, RECOMBINED CELL, AND ISOPRENE OR CYCLIC TERPENE PRODUCTION METHOD
Provided is a nucleic acid encoding a fusion protein, the fusion protein including a first protein selected from the group consisting of isoprene synthase and...
2018/0023097 METHODS OF PRODUCING FOUR CARBON MOLECULES
Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, ...
2018/0023096 A CRISPR-CAS SYSTEM FOR A LIPOLYTIC YEAST HOST CELL
The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention relates to a CRISPR-CAS system for a...
2018/0023095 DATA LOGGING DEVICE
A device and a method to sense changes in the environment and log the sensed changes.
2018/0023094 RECOMBINANT AAV VARIANTS AND USES THEREOF
The disclosure in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the disclosure...
2018/0023093 PEPPER HYBRID DR2179PB AND PARENTS THEREOF
The invention provides seed and plants of pepper hybrid DR2179PB and the parent lines thereof. The invention thus relates to the plants, seeds and tissue...
2018/0023092 FLAGELLIN-SENSING 3 ('FLS3') PROTEIN AND METHODS OF USE
One aspect of the present invention relates to a nucleic acid construct that includes a nucleic acid molecule that encodes FLAGELLIN-SENSING 3 ("FLS3")...
2018/0023091 METHOD FOR INDUCING TARGETED MEIOTIC RECOMBINATIONS
The present invention relates to a fusion protein comprising a Cas9 domain and a Spo11 domain, as well as the use of this protein to induce targeted meiotic...
2018/0023090 METHODS FOR PLANT TRANSFORMATION USING SPECTINOMYCIN SELECTION
The present invention relates to methods and compositions for transforming soybean, corn, cotton, or canola explants using spectinomycin as a selective agent...
2018/0023089 Methods for Dynamic Vector Assembly of DNA Cloning Vector Plasmids
A method for using cloning vector plasmids to produce DNA molecules, such as transgenes, in a single cloning step. The transgenes can be used for the purpose...
2018/0023088 MATERIALS AND METHODS FOR THE BIOSYNTHESIS OF SEVEN CARBON CHEMICALS IN THE PRESENCE OF METHANOL OXIDATION
This disclosure describes methods for regulating the biosynthesis of pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine,...
2018/0023087 Screening Method For Compound Having Obesity Preventive Or Therapeutic Activity
To provide a screening method for a substance having an anti-obesity action and an anti-obesity drug. A screening method including: a step for contacting a...
2018/0023086 Compositions and Methods for Inhibiting Gene Expression of Factor XII
RNA interference (RNAi) triggers for inhibiting the expression of Factor XII (F12) gene through the mechanism of RNA interference are described. Pharmaceutical...
2018/0023085 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE
The invention provides novel immune regulatory oligonucleotides (IRO) as antagonist of TLRs and methods of use thereof. These IROs have unique sequences that...
2018/0023084 Disulfide-Containing Alkyne Linking Agents
Described are improved disulfide-containing alkyne linking agents having have branched disulfides. The improved linking agents exhibit improved stability. The...
2018/0023083 DOUBLE STRAND RNA AS MOLECULAR BIOPESTICIDES FOR RNA INTERFERENCE THROUGH FEEDING IN THE HEMIPTERAN INVASIVE...
The present disclosure provides compositions and methods of delivering double strand ribonucleic acid (dsRNA) to control the insect pest, the brown marmorated...
2018/0023082 VARIANT RNAi
Provided herein are RNAi molecules including a first strand containing a guide sequence and a second strand comprising a non-guide sequence where the non-guide...
2018/0023081 LNA OLIGONUCLEOTIDES WITH ALTERNATING FLANKS
The present invention relates to LNA oligomers having two flanks, wherein one or both flanks comprise alternating LNA and DNA nucleosides.
2018/0023080 Long Non-Coding RNA For The Treatment Of Endothelial Dysfunction
The present invention associates multiplelong non-coding RNA (lncRNA) with key functions of endothelial cells. The lncRNA of the present invention are...
2018/0023079 Circular RNA For The Diagnosis Of Cardiovascular And Inflammatory Diseases
The present invention associates multiple circular (circRNA) with key functions of endothelial cells. The present invention provides circRNA transcripts that...
2018/0023078 Oligonucleotide Sequences Targeting Transcription FactorTSC22D4 for the Treatment of Insulin Resistance
The present invention relates to oligonucleotide inhibitors of the TSC22D4 activity or expression and their uses for the prevention, treatment, and/or...
2018/0023077 COMPOSITIONS FOR MODULATING EXPRESSION OF C9ORF72 ANTISENSE TRANSCRIPT
Disclosed herein are compositions and methods for reducing expression of C9ORF72 antisense transcript in an animal with C9ORF72 antisense transcript specific...
2018/0023076 DOUBLE STRAND RNA DELIVERY SYSTEM FOR PLANT-SAP-FEEDING INSECTS
The present disclosure provides compositions and methods of delivering double strand ribonucleic acid (dsRNA) to insects that penetrate plant tissues to feed...
2018/0023075 COMPOSITIONS AND METHODS FOR ENHANCING HOMOLOGOUS RECOMBINATION
The present disclosure generally relates to compositions and methods for improving the efficiency of homologous recombination. In particular, the disclosure...
2018/0023074 LONG NUCLEIC ACID SEQUENCES CONTAINING VARIABLE REGIONS
This invention pertains to improved methods for the synthesis of long, double stranded nucleic acid sequences containing difficult to clone or variable regions.
2018/0023073 ALDOLASE, ALDOLASE MUTANT, AND METHOD AND COMPOSITION FOR PRODUCING TAGATOSE BY USING SAME
There are provided aldolase, an aldolase mutant, a method for producing tagatose, and a composition for producing tagatose using the same. The technical...
2018/0023072 BETA-LACTAMASES WITH IMPROVED PROPERTIES FOR THERAPY
This invention relates to, in part, compositions of beta-lactamases and methods of using these enzymes in, for example, gastrointestinal tract (GI tract)...
2018/0023071 PEPTIDES DERIVED FROM HUMAN PCSK9 CATALYTIC DOMAIN AND USES THEREOF FOR PROMOTING LDL-R ACTIVITY
The present invention provides compositions comprising an isolated or purified therapeutically effective hPCSK9 polypeptide derived from the hPCSK9 catalytic...
2018/0023070 CYSTEINE PROTEASE
The present invention relates to a novel polypeptide which displays IgG cysteine protease activity, and in vivo and ex vivo uses thereof. Uses of the...
2018/0023069 PROTEASE VARIANTS HAVING AN IMPROVED WASHING PERFORMANCE
The disclosure relates to proteases, the amino acid sequence of which has been modified in particular with regard to the use thereof in detergents and cleaning...
2018/0023068 NOVEL METALLOPROTEASES
Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods...
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