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Patent # Description
2018/0028563 COMBINATION THERAPIES FOR BLADDER CANCER
The disclosure provides drug combinations and methods for treating human bladder cancer. The drug combination may include mitomycin, or an analogue thereof,...
2018/0028562 METHODS OF TREATING OR PREVENTING INFLAMMATION AND HYPERSENSITIVITY WITH OXIDATIVE REDUCTIVE POTENTIAL WATER...
Provided is a method for preventing or treating inflammation and associated states (e.g. infection, hypersensitivity, pain) by administering a therapeutically...
2018/0028561 METHOD FOR PREPARING A LIPOSOMAL REHYDRATION SALT FORMULATION
A liposomal rehydration salt formulation comprising phosphatidylcholine liposomes, salts, water, and a percentage inclusion ratio of salts (salts retained...
2018/0028560 SELENIUM-CONTAINING COMPOSITIONS AND USES THEREOF
The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent...
2018/0028559 SELENIUM-CONTAINING COMPOSITIONS AND USES THEREOF
The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent...
2018/0028558 THERAPEUTIC POLYSACCHARIDE MIDI-GAGR AND RELATED MATERIALS AND METHODS
Described herein are materials and methods useful for the treatment of neurodegenerative disorders as well as bone disorders in a subject. Materials described...
2018/0028557 HYBRID OLIGONUCLEOTIDES AND USES THEREOF
Provided herein are hybrid oligonucleotides comprising a region that promotes cleavage of a nucleic acid and a region that protects a nucleic acid from...
2018/0028556 METHODS OF TREATING OPTIC DISORDERS
The present invention relates to methods for treating optic disorders or for reducing or alleviating the signs, symptoms, or pathological conditions related to...
2018/0028555 2'-METHOXY SUBSTITUTED OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN GENE MODULATIONS
Compositions comprising first and second oligomers are provided wherein at least a portion of the first oligomer is capable of hybridizing with at least a...
2018/0028554 Oligomers Having Bicyclic Scaffold Moeities
The current invention provides oligomers with improved characteristics that enhance clinical applicability for treating, ameliorating, preventing a disorder or...
2018/0028553 USE OF STING AGONIST AS CANCER TREATMENT
Methods and compositions for treating cancer by intratumorally administering a stimulator of interferon genes (STING) agonist are disclosed herein.
2018/0028552 COMBINATION THERAPY FOR TREATING CANCER
The present disclosure relates to a combination of an inhibitor of human histone methyltransferase DOT1L, such as EPZ-5676 or salts thereof, and one or more...
2018/0028551 Treatment of Diseases Using Combination of Ultraviolet Blood Irradiation and Antibiotics
A method of and composition for treating a patient having Mycobacterium avium complex (MAC), and in one embodiment Mycobacterium avium subspecies ...
2018/0028549 PHARMACEUTICAL COMPOSITIONS
The lyophilized solid pharmaceutical compositions comprising a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof...
2018/0028548 PHARMACEUTICAL COMPOSITIONS
The stable pharmaceutical compositions comprising a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof are...
2018/0028547 COMPOUND FROM THE AVERMECTIN FAMILY FOR TREATING AND/OR PREVENTING FOLLICULITIS
A compound from the avermectin family is described for use in treating and/or preventing folliculitis caused by anti-cancer agents and more particularly by...
2018/0028546 COMPOUNDS AND COMPOSITIONS FOR IMPROVING POWER OUTPUT AND OXYGEN EFFICIENCY
The present invention provides the use of a compound of formula I, and compositions comprising such a compound, for improving power output and/or oxygen...
2018/0028545 PHOSPHOLIPID COMPOSITIONS
Compositions involving a modified egg yolk extract for use as an effective anti-cancer agent are described. The modified egg yolk extract involves specific...
2018/0028544 NERIDRONIC ACID FOR TREATING COMPLEX REGIONAL PAIN SYNDROME
Oral dosage forms of osteoclast inhibitors, such as neridronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
2018/0028543 HYPOLIPIDEMIC COMPOSITION AND USE THEREOF
A composition has ornithine, aspartic acid and vitamin B6, and it is used in preparation of hypolipidemic drugs, health-care products, foods or food additives.
2018/0028542 PHARMACEUTICAL DELIVERY SYSTEMS FOR HYDROPHOBIC DRUGS AND COMPOSITIONS COMPRISING SAME
A drug delivery system for oral administration of hydrophobic drugs with enhanced and extended absorption and improved pharmacokinetics is provided. In one...
2018/0028541 CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS...
The present disclosure relates to methods for treating bronchiectasis, for example, non-cystic fibrosis bronchiectasis with compositions comprising an...
2018/0028540 ANTI-VIRAL COMPOSITIONS CONTAINING PIKFYVE INHIBITORS AND USE THEREOF
The present invention relates to compositions containing a PIKfyve inhibitor, preferably apilimod, APY0201 or YM-201636, most preferably apilimod, for use in...
2018/0028539 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
Provided are crystalline forms of 2-Methyl-1-[(4-[6-(trifluoromethyl) pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-- ...
2018/0028538 NOVEL COMPOSITION FOR TREATMENT OF ESSENTIAL THROMBOCYTHEMIA
The present invention relates to a novel pharmaceutical composition free of gastric coating comprising anagrelide hydrochloride in combination with a non-pH...
2018/0028537 Novel Formulations of a Bruton's Tyrosine Kinase Inhibitor
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pi- ...
2018/0028536 INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS
A novel therapeutic drug for malignant tumors, cancer stem cells, or fibrosis is obtained. A therapeutic drug for malignant tumors or cancer stem cells is used...
2018/0028535 3-HYDROXYPYRIMIDINE-2,4-DIONE-5-CARBOXAMIDES AS POTENT INHIBITORS OF HIV
Various embodiments described herein are directed to compounds of formula (I), (II), (III) or (IV) for use as potent inhibitors of HIV integrase and for...
2018/0028534 SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRI- ...
Provided herein are formulations, processes, solid forms and methods of use relating to ...
2018/0028533 Medicinal solution to be continuously or pulse-delivered to the eye for treating ophthalmological...
The present invention relates generally to a medicinal solution, and more particularly to a medicinal solution which is to be continuously or pulse-delivered...
2018/0028532 AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS
The present invention provides a compound of Formula (I) or a salt thereof; ##STR00001## and therapeutic uses of these compounds. The present invention further ...
2018/0028531 USE OF PLINABULIN IN COMBINATION WITH IMMUNE CHECKPOINT INHIBITORS
Disclosed herein are compositions comprising Plinabulin and one or more immune checkpoint inhibitor for treating cancer. Some embodiments relate to methods of...
2018/0028530 Role of N-2-Hydroxy-Ethyl-Piperazine-N'-2-Ethane Sulfonic Acid (HEPES) in Pain Control and Reversal of...
Compositions and therapeutic uses of HEPES and derivatives in the treatment of pain associated with cancers and side-effects including post-chemotherapy...
2018/0028529 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITIONS OF OPIOIDS AND OTHER DRUGS
An abuse-deterrent pharmaceutical composition has been developed to reduce the likelihood of improper administration of drugs, especially drugs such as...
2018/0028528 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITIONS OF OPIOIDS AND OTHER DRUGS
An abuse-deterrent pharmaceutical composition has been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opiods....
2018/0028527 ABUSE DETERRENT COMPOSITIONS AND METHODS OF MAKING SAME
This invention relates a therapeutic pharmaceutical composition comprising: a mixture including an opioid; polyethylene oxide in an amount of about 3 to about...
2018/0028526 NALMEFENE FOR REDUCTION OF ALCOHOL CONSUMPTION IN SPECIFIC TARGET POPULATIONS
The present invention relates to nalmefene for use in the reduction of alcohol consumption in a patient with alcohol dependence who has a high drinking risk...
2018/0028525 COMPOSITIONS AND METHODS FOR ACHIEVING SUSTAINED THERAPEUTIC DRUG CONCENTRATIONS IN A SUBJECT
Provided herein are compounds and methods for achieving a sustained therapeutic effect of small molecule anti-cancer agents when administered in vivo. ...
2018/0028524 PREPARATION AND ANTI-HSV-1 APPLICATION OF QUINOLINONE DERIVATIVES
Provided herein are quinolinone derivatives and their uses as antiviral drugs, for example, for treatment of HSV-1 infection. Also provided herein are...
2018/0028523 ALKALOIDS AND THEIR PREPARATION AND APPLICATION AS ANTI-HSV-1 AGENTS
The present invention provides alkaloids with formula I, II, III, IV, or V and their pharmaceutically acceptable salts, their preparation and their uses as...
2018/0028522 QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF VIRAL INFECTION
The present invention relates to a quinoline derivative of formula (I) or anyone of its pharmaceutically acceptable salt, or anyone of its metabolites, for use...
2018/0028521 Methods of Treating Prostate Cancer
Disclosed are methods of treating prostate cancer by administering niraparib to a human in need thereof.
2018/0028520 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
The present disclosure provides, inter alia, methods and pharmaceutical compositions for treating or ameliorating amyotrophic lateral sclerosis (ALS). Among...
2018/0028519 Use of Flecainide as an Anti-Connexin Agent and Method for Potentiating the Effects of a Psychotropic Drug
The present invention relates to the use of flecainide as an anti-connexin agent. This anti-connexin agent is advantageously used to potentiate the therapeutic...
2018/0028518 Heterocyclic Compounds and Methods of Use
This disclosure provides compounds and methods of using those compounds to treat liver fibrosis, including liver fibrosis which is a precursor to, is...
2018/0028517 BENZIMIDAZOLE SULFIDE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF TUBERCULOSIS
The present invention relates to the use of benzimidazole sulfide derivatives and prodrugs thereof in the treatment and/or prevention of tuberculosis.
2018/0028516 METHODS AND DEVICES FOR THE TREATMENT OF OCULAR DISEASES IN HUMAN SUBJECTS
Methods and devices are provided for targeted non-surgical administration of a drug formulation to the suprachoroidal space (SCS) of the eye of a human subject...
2018/0028515 PYRIDINONE COMPOUND AND USE THEREOF
The present invention provides a compound capable of being used as an active ingredient of an anti-cancer agent. To provide an anti-cancer agent with few side...
2018/0028514 Compositions and Methods for Treatment of Edema
Provided are pharmaceutical compositions and methods of treating or preventing edema, using an anti-T cell agent, an anti-TGF-.beta. agent, or an...
2018/0028513 METHODS FOR TREATING AN IMPAIRMENT IN GAIT AND/OR BALANCE IN PATIENTS WITH MULTIPLE SCLEROSIS USING AN...
Disclosed herein is use of one or more aminopyridines in methods and compositions for treatment of impairments in gait or balance in patients with multiple...
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