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Patent # Description
2018/0036295 METHODS FOR TREATING PROTEINOPATHIES
This disclosure relates to a method of treating a proteinopathy in a subject, the method comprising administering to the subject an effective amount of a...
2018/0036294 9H-PYRIMIDO [4,5-B] INDOLES AS BET BROMODOMAIN INHIBITORS
The present disclosure provides substituted 9H-pyrimido [4,5-b] indoles and 5H-pyrido [4,3-b] indoles and related analogs represented by Formula I and the...
2018/0036293 CERTAIN PROTEIN KINASE INHIBITORS
Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
2018/0036292 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BACTERIAL INFECTIONS
The methods of treating bacterial infection by administering a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof...
2018/0036291 Penicillin Retard Composition For Intramuscular Injection
The present invention is directed to an injection syringe comprising an injectable composition, the composition comprising a penicillin, salt or prodrug...
2018/0036290 RILUZOLE PRODRUGS AND THEIR USE
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain...
2018/0036289 COBICISTAT FOR USE IN CANCER TREATMENTS
The disclosure describes methods for and compositions for treatment of patients having cancers expressing CYP3A enzymes by co-administration of cobicistat with...
2018/0036288 PHARMACEUTICAL COMPOSITION CONTAINING MIRABEGRON
To provide: (1) a modified release liquid (suspension) containing mirabegron, (2) a ready-to-suspend pharmaceutical composition containing mirabegron, and (3)...
2018/0036287 BENZOTHIAZOLE AND BENZOTHIOPHENE COMPOUNDS
The present invention provides benzothiazole compounds or benzothiophene compounds of Formula I having the structure: wherein X.sup.1, X.sup.2, X.sup.3,...
2018/0036286 BIS-CYCLIC GUANIDINE COMPOUND COMPOSITIONS, METHODS OF USE AND TREATMENT THEREOF
The present disclosure provides compositions including a bis-cyclic guanidine compound, pharmaceutical compositions including a bis-cyclic guanidine compound,...
2018/0036285 METHODS AND COMPOSITIONS FOR REVERSING DISRUPTION OF THE GLYCOCALYX, INFLAMMATION, AND OXIDATIVE DAMAGE
A composition for treating multiple disease causes including a glycocalyx restoring and maintaining compound. A method of treating multiple disease causes, by...
2018/0036284 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY
Biologically active compounds that can be used as photosensitizers for diagnostic and therapeutic applications, particularly for PDT of cancer, infections and...
2018/0036283 INDOLE-BASED THERAPEUTICS
Provided herein are indole-2-carboxamide compounds useful for the treatment of non-tuberculosis bacterial infections. Exemplary compounds provided herein are...
2018/0036282 STABILIZED STATIN FORMULATIONS
The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
2018/0036281 PHARMACEUTICAL FOR PROPHYLAXIS OR TREATMENT OF HYPERTENSION
A pharmaceutical for the prophylaxis or treatment of hypertension or a disease derived from hypertension. The pharmaceutical is characterized by comprising (i)...
2018/0036280 PHARMACEUTICAL COMBINATION COMPRISING METFORMIN AND DIHYDROQUERCETIN AND ITS USE FOR THE TREATMENT OF CANCER
Provided is a novel medicament capable of reducing the side effects of metformin or a pharmaceutically acceptable salt thereof and useful as an anti-malignant...
2018/0036279 MULTIVITAMIN CAPABLE OF BENEFICIAL GENE REGULATION THROUGH MICRORNA (MIRNA)
The present invention includes compositions and methods for modifying the expression of microRNAs comprising: one or more plant secondary metabolites capable...
2018/0036278 CPC DISTRIBUTION CHROMATOGRAPHY OF CANNABINOIDS
The invention relates to cannabinoids and their isolation and purification and to obtaining them by means of centrifugal partition chromatography.
2018/0036277 C14-HYDROXYL ESTERIFIED AMINO ACID DERIVATIVE OF TRIPTOLIDE, AND PREPARATION METHOD AND USE THEREOF
The present invention belongs to the field of natural medicines and medicinal chemistry, and relates to novel esterified amino acid derivatives of triptolide...
2018/0036276 COMBINATION COMPRISING N-ACETYL-L-CYSTEINE AND ITS USE
A combination of N-acetyl-L-cysteine, selenium in the form of selenomethionine and melatonin, and a medical product or pharmaceutical composition comprising...
2018/0036275 COMBINATION OF A RETINOID AND A DIOL AND POLYUNSATURATED FATTY ACID ESTER
The present invention concerns a combination of a retinoid and a diol and polyunsaturated fatty acid ester, a dermatological or dermocosmetic composition...
2018/0036274 USE OF MEDIUM CHAIN TRIGLYCERIDES FOR THE TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES...
Methods and compositions for treating or preventing, the occurrence of senile dementia of the Alzheimer's type, or other conditions arising from reduced...
2018/0036273 APPLICATION OF CHLOROGENIC ACID IN PREPARING MEDICINES FOR TREATING MELANOMA AND MEDICINES FOR TREATING MELANOMA
The present invention provides an application of chlorogenic acid in preparing medicines for treating melanoma and a pharmaceutical composition comprising...
2018/0036272 PHARMACEUTICAL COMPOSITIONS COMPRISING DGLA AND USE OF SAME
The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions...
2018/0036271 Diagnostic Assay and Treatment for Preeclampsia
Described is a method of diagnosis or prognosis of preeclampsia in a pregnant subject, comprising providing a sample from a pregnant subject and measuring the...
2018/0036270 A METHOD OF PROTECTING AGAINST CARBONYL STRESS INDUCED ISCHEMIA-REPERFUSION INJURY IN THE DIABETIC BRAIN VIA...
A method for one of preventing and minimizing diabetes pathology in a mammal, comprising administering to the mammal an effective amount of N-acetylcysteine...
2018/0036269 Topical Pharmaceutical Formulation
Herein described is a topical composition for application of an NSAID, the composition comprising a solution or suspension of the NSAID as active ingredient in...
2018/0036268 Treatment of intrahepatic cholestatic diseases
Treatment of intrahepatic cholestatic diseases by therapy with MBX-8025 or an MBX-8025 salt.
2018/0036267 COMPOSITIONS CONTAINING BENZOATE COMPOUND AND TANNIC ACID FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS
Compositions (e.g., pharmaceutical compositions or nutraceutical compositions) comprising a benzoate compound and an excipient, wherein the excipient is tannic...
2018/0036266 ANTIVIRAL COMPOSITIONS AND METHODS FOR INACTIVATING NON-ENVELOPED VIRUSES USING ALKYL 2-HYDROXYCARBOXYLIC ACIDS
The present invention is directed to antiviral compositions that provide efficacy against non-envelope viruses such as noroviruses. The antiviral compositions...
2018/0036265 Use of 2,5-Dihydroxybenzene Derivatives for Treating Dermatitis
The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate,...
2018/0036264 TARGETING LIVER NUCLEAR RECEPTORS AS A TREATMENT FOR WILSON DISEASE
The present invention relates to the field of Wilson Disease. More specifically, the present invention provides methods and compositions useful for treating...
2018/0036263 STABILIZED FORMULATION OF TRIAMCINOLONE ACETONIDE
A stabilized formulation of triamcinolone acetonide in a bioadhesive base material is provided. The present invention further includes a method of producing a...
2018/0036262 CHEMICALLY MODIFIED CURCUMINS FOR USE IN THE PRODUCTION OF LIPOXINS
A method of increasing production of one or more lipoxins in a subject in need thereof comprising administering to the subject an amount of a compound having...
2018/0036261 Multi-Step Connective Tissue Stabilization Method and Stabilized Tissue Formed Thereby
A multi-step stabilization method for connective tissue is described. Stabilized tissues can exhibit increased resistance to degradation due to enzyme...
2018/0036260 DIMETHOXYPHENYL INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2
Described are dimethoxyphenyl inhibitors of VMAT2, pharmaceutical compositions thereof, and methods of use thereof.
2018/0036259 NO DONORS FOR THE TREATMENT OF IMPAIRED TISSUE PERFUSION
A method for treatment of prophylaxis of a chronic disease or condition associated with impaired tissue or organ perfusion, comprising administering an...
2018/0036258 ACTIVE SUBSTANCES AND COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID ACTIVE SUBSTANCES FOR THE CARE OF...
Licochalcone A and/or plant extracts or microbiologically obtained extracts with an active content of Licochalcone A or cosmetic or dermatological preparations...
2018/0036257 ZEAXANTHIN FOR TUMOR TREATMENT
A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a...
2018/0036256 INTERACTION OF METHYLATED LSD1 AND CHD1, A COMPOUND INHIBITING THIS INTERACTION FOR USE IN THERAPY, AND A...
Disclosed in the present application are: (i) a compound inhibiting the interaction between LSD1me2 and CHD1 for use in therapy, (ii) a compound inhibiting the...
2018/0036255 GEL PATCH
A method for producing a gel patch comprising an adhesive mass layer on a backing fabric, comprising a step of applying a composition comprising a ...
2018/0036254 NOVEL RNAi MOLECULE DELIVERY PLATFORM BASED ON SINGLE-siRNA AND shRNA NANOCAPSULES
Novel siRNA and shRNA nanocapsules and delivery methods are disclosed herein. These siRNA and shRNA nanocapsules and delivery methods are highly robust and...
2018/0036253 Dosator Apparatus for Filling a Capsule with Dry Powder
The invention relates to a dosator which comprises a tapered elongate cavity; a stationary plunger disposed within the cavity; a removable mesh screen disposed...
2018/0036252 PHARMACEUTICAL SOFT GELATIN CAPSULE DOSAGE FORM WITH MODIFIED GUAR GUM
A pharmaceutical soft gelatin capsule dosage form that includes (a) a shell that includes gelatin; and (b) a fill that includes at least one active ingredient,...
2018/0036251 PHARMACEUTICAL DOSAGE FORM FOR APPLICATION TO MUCOUS MEMBRANES
The present invention relates to a pharmaceutical dosage form for application to a mucous membrane, in particular to a buccal, intestinal, rectal or vaginal...
2018/0036250 SOLID PREPARATION
Provided is a solid preparation showing improved stability of N-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyr- ...
2018/0036249 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER
The present invention pertains to a pharmaceutical composition comprising the compound of the formula (I) in a high concentration and at least one ...
2018/0036248 CURCUMIN SOLID LIPID PARTICLES AND METHODS FOR THEIR PREPARATION AND USE
Solid lipid particles comprising a lipid hydrophobic matrix and from about 5 wt. % to about 30 wt. % of curcumin, and methods of making and treatment thereof.
2018/0036247 Pharmaceutical Compositions
Disclosed herein are pharmaceutical powder compositions, methods of making such compositions, and uses thereof.
2018/0036246 PHARMACEUTICAL COMPOSITIONS OF GOSERELIN SUSTAINED RELEASE MICROSPHERES
A composition of goserelin sustained release microspheres is provided. The microspheres comprise goserelin, at least one poly (lactide-co-glycolide) and...
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